I taksaa calcium control tu secret mastermind: Parathyroid Hormone (PTH) chungchang i zir dawn nia.

Kan taksa chhungah hian chemical messenger te tak te, hmuh theih loh, hrisel taka awm turin hna thawk kan nei vek a. Chutiang thuchah pakhat chu parathyroid hormone a ni. A awlsam zawngin sawi ila, he hormone hian kan thisena calcium awm zat a control a ni. Engvangin nge a pawimawh em em? A chhan chu kan nerve, muscle leh thinlung hnathawh that nan calcium hi a pawimawh hle a ni.

He parathyroid hormone (Parathyroid Hormone - PTH) hi kan parathyroid glands siam a ni. Chungte chu kan kawr chhungah, thyroid gland hnung lamah a awm a. Gland te tak te tak tak pali an ni. An hna ber chu kan thisena calcium awm zat control hi a ni . Ruh chhunga calcium awm hi a ni lo va, thisen a calcium awm hi a ni tih hre reng ang che. Tin, he PTH hian thisen leh ruh chhunga mineral phosphorus leh hormone vitamin D te control nan a pui bawk.

Engtin nge parathyroid hormone (PTH) hian hna a thawh?

Okay, tunah chuan he parathyroid hormone (PTH) hnathawh dan hi han en ila. I thisena calcium level a tlahniam chuan parathyroid glands te hian PTH an tichhuak thin. Sensor ang mai a ni. He PTH hian a kal a, kan taksa hmun engemaw zat a nghawng a, calcium level a ti sang leh ta a ni.

• Ruh: A hmasa berin kan ruhte hi signal tlem pek a ni a, ‘Thisenah calcium tlem tal chhuah tir rawh’ tih a ni. Tichuan ruh atanga calcium tlem te te chu thisenah an dah lut leh thin. Hei hian ruh a tichak lo lo, a chhan chu hei hi controlled process a nih vang a ni.
• Kidney: Pahnihnaah chuan kan kal (kidney) a nghawng a ni. Pakhat chu kal hian active vitamin D siam a pui a, chu chu calcitriol an ti a ni. He calcitriol hian taksain kan ei leh in atanga calcium a lakluh theih nan a pui thin. Thil dang chu kal (kidney) te hnenah ‘calcium chu taksaah vawng reng la, zun nen chhuah tir suh’ tiin a hrilh a ni. Tichuan calcium chu a bo lo ang.
• Small Intestine: Pathumnaah chuan, a hmaa kan sawi tawh ang khan vitamin D (Calcitriol) hian kan small intestine-ah signal a thawn a, kan ei leh in atanga calcium tam zawk hip lut turin signal a thawn a.

Chutiang chuan PTH hian taksa peng hrang hrang a nghawng avangin thisena calcium level chu a level dik takah a awm theih nan hna a thawk a ni. Hei hi mechanism mak tak a ni lo maw?

Engtin nge kan taksa hian PTH level a control?

Engtin nge kan taksa hian he PTH level hi a control? Thil mak tak maiin a thleng bawk. Feedback loop an ti a ni. A awlsam zawngin thisena calcium a tlahniam chuan parathyroid glands te chu an tichak a, PTH an chhuah tir thin. Thisen a calcium a pun chuan glands te chu ‘tunah chuan PTH siam tawh lo rawh, a tawk tawh’ tiin signal a pe thin. Chuvangin chutiang chuan control a ni. In chhunga motor pakhat, tui tank chhunga tui a tlem laiin a on a, tank a khat laiin a off ang mai a ni.

Mahse, a chang chuan kan parathyroid glands-ah harsatna a awm chuan he feedback loop hian hna a thawk tha lo thei a, PTH tam lutuk emaw, tlem lutuk emaw a siam thei a ni. Chutah chuan harsatna chu a intan ta a ni.

PTH level tihbuai a nih chuan eng natna nge lo awm thei?

Tunah chuan parathyroid hormone (PTH) level a tihbuai chuan eng hriselna dinhmun nge lo awm thei tih i lo en ang u.

PTH level a san chuan eng nge thleng ang? (Hyperparathyroidism) tih a ni.

PTH level a san lutuk chuan hyperparathyroidism kan ti thin. Tichuan thil pawimawh pahnih a thleng ta a:

• Thisen a calcium level a sang chho zel a . Hei hi hypercalcemia an ti a.
• Thisen a phosphorus level a tlahniam a . Hei hi hypophosphatemia an ti a.

Ngaihtuah teh, PTH hian ruh atanga thisenah calcium a chhuah chhunzawm zel a, kal (kidney)-in calcium a chhuah loh nan a titawp a, ei tur atanga a lakluh tam zawk bawk... chutah chuan thisen chu calcium-in a khat ta a ni lawm ni? Hei hi pipe a inkhar a, tui a luang chhuak ang mai a ni.

Hetiang dinhmun hi a chhan hrang hrang a awm thei a, chungte chu:

• Parathyroid Adenoma: Hei hi cancer a ni lo, mahse he tumor hian gland hian PTH a siam tam lutuk a. Hei hi a chhan tam ber a ni.
• Parathyroid Hyperplasia: Gland palite hi an lian vek a, hormone tam zawk an siam chhuak vek a.
• Kidney Disease: He natna hi a bik takin hun rei tak chhunga kal natna nei te tan a awm thei a ni. A chhan chu kal (kidney)-in hna a thawh that loh chuan vitamin D siamchhuahna a tlahniam a, phosphorus chhuahna pawh a tlahniam bawk. Hei hian parathyroid glands te chu PTH tam zawk siam turin a tichak a ni.
• Parathyroid Cancer: Hei hi a tlem hle a, mahse a thleng thei.

PTH level a tlahniam chuan eng nge thleng ang? (Hypoparathyroidism) tih a ni.

PTH level a hniam chuan hypoparathyroidism an ti a ni. Tichuan a kalh zawngin a thleng ta a ni:

• Thisena calcium level hniam. Hei hi hypocalcemia an ti a.
• Thisen a phosphorus level a sang chho zel a . Hei hi hyperphosphatemia an ti a.

Hypoparathyroidism hi a awm ve lo. A tam zawk (75%) chu kawng surgery neih laiin parathyroid glands accident-a tihchhiat emaw, lakchhuah emaw avanga lo awm a ni a, a bik takin thyroid surgery-ah a ni. Tin, genetic condition thenkhat leh autoimmune condition – taksa immune system-in a cell a beih natna vang pawh a ni thei bawk.

Engtin nge i PTH level a dik lo tih i hriat theih ang? Eng nge a lan chhuah dan?

Kan sawi tawh ang khan PTH hian thisen a calcium awm zat a control ber a ni. Chuvangin PTH level hniam emaw sang emaw a awm thin symptoms te hi a takah chuan thisena calcium level hniam emaw sang emaw symptoms a ni. Eng nge an nih i en ang u.

Thisena calcium tlahniam (Hypocalcemia) chhinchhiahna: 1.1.

Hetiang thil hi i hre mai thei:

• Brain fog emaw, buaina emaw. I lu chu vur in a khuh ang maiin a awm thei.
• Vun a vawt a, nail a chhe awlsam a, sam a tla chhuak bawk.
• Muscle cramps, a bik takin ke leh kut ah.
• I hmui, kut zungtang emaw keah emaw tingling.
• Lungkhamna leh lungngaihna ang chi thil pawh a thleng thei bawk.
• A nasat chuan seizures a awm thei.

Ngaihtuah teh, Niluka chuan a kut zungtang chu a hrual nghal vek a, a hmui vel chu a rawn ri chhuak a, a ke ruh sa chu a sen tan ta a ni. A rilru a hah hle mai. Doctor a pan meuh chuan a thisena calcium level a tlahniam tih a hre ta a, a chhan chu hypoparathyroidism a ni.

Thisen calcium sang (Hypercalcemia) chhinchhiahna: 1.1.

Hetiang symptoms hian thisenah calcium a tam tih a tilang thei:

• Ka chau hle tih ka hria, chakna nei lo ang maiin (Fatigue). Eng ang pawhin mu mah ila, hahna chu a reh lo niin a lang.
• Lu na.
• Joint na leh ruh na.
• Zun tam zawk mamawh leh tuihal lutuk.
• Thil chi hrang hrang, pum na, luak chhuak, luak chhuak, leh ril\am te.
• Thil ngaihtuah harsa a ni a, hriatrengna a tlahniam a, rilru a buai bawk.
• A nasat chuan kal (kidney stone) leh heartbeat mumal lo (irregular heartbeat) a awm thei.

Entirnan, Uncle Saman-a chuan ni engemaw zat chu a chau hle a, a ruhte pawh a na hle bawk. A tuihal reng a, bathroom kal a ngai a ni. Doctor-in a check chuan a thisen calcium a sang deuh tih an hrilh a. Hyperparathyroidism a nei a ni.

Heng symptoms te hi i neih chuan, i thisen calcium level a hniam emaw a sang emaw ang tih i hriat chuan doctor i pan ngei tur a ni . Chu chu theihnghilh suh. Hengte hi ngaihthah tur symptom tha tak a ni lo.

PTH level hi engtin nge kan check ang?

I doctor chuan i parathyroid hormone level chu thisen test awlsam tak hmangin a enfiah thei ang . Doctor leh lab-te chuan he test hi “PTH, intact” tiin an sawi thin. Tin, i thisena calcium, phosphorus leh vitamin D awm zat an enfiah tlangpui bawk a, chu chuan thlalak kimchang tak a hmu thei a ni.

PTH level hrang hranga normal value te chu engte nge ni?

PTH thisen test pangngaiah chuan hrisel level chu milliliter khatah picogram 15 leh 65 inkar a ni (pg/mL) . Picogram chu gram tluklehdingawn khat a ni. Chu chu a tlem lutuk hian kan taksaah hian he hna pawimawh tak hi a thawk tihna a ni.

Mahse thil pakhat hriat reng tur chu heng normal value te hi lab hrang hrangah hian a danglam deuh thei a ni. Chuvangin, i thisen test report-ah chuan chu lab atana normal range chu i en reng tur a ni.

PTH test i neih chuan i doctor chu a result dik taka hrilhfiahtu tur a ni ang. I calcium level nen a khaikhin ang a, test belh a ngai em tih a hrilh ang che.

Chuti a nih chuan, heng zawng zawng atang hian eng thil nge kan hriat reng tur?

Parathyroid Hormone (PTH) hi hormone pawimawh tak a ni a, kan thisena calcium awm zat chiang takin a control thei a ni. He calcium level hi kan nervous system, muscle leh thinlung hrisel taka hnathawhna atan a pawimawh hle.

Hypercalcemia (thisen calcium sang) emaw hypocalcemia (thisen calcium tlem) emaw symptoms i neih chuan taksa ruh lama harsatna, rilru hnathawh dan inthlak danglam, hah lutuk, ruh na te i neih chuan tihkhawtlai lova damdawi lam pan a pawimawh. Heng dinhmunte hi a awm reng chuan kal, thinlung leh ruhte a tichhia thei a ni.

I doctor chuan i parathyroid hormone level hi a chhan a nih leh nih loh hriat nan test awlsam tlemte a kalpui thei ang. Chutiang a nih chuan enkawlna an tan nghal thei a ni. A chang chuan heng harsatnate hi damdawi hmanga enkawl theih a ni a, a chang chuan surgery tenau tak tak hmanga enkawl theih a ni bawk. Chuvangin, i taksa enkawl a, a signal pekte hriatthiam a, chutianga tih chu hrisel taka awm theihna kawng tha ber a ni.

` Parathyroid hormone, PTH, calcium, hyperparathyroidism, hypoparathyroidism, hypercalcemia, hypocalcemia