Cancer enkawlna neih hi thil harsa tak a ni thei tih kan hria. I doctor-in damdawi thar a sawi hian zawhna a lo lang fo thin. Vawiin hian chutiang cancer dona damdawi bik pakhat, Aldesleukin chungchang kan sawi dawn a ni. A chang chuan IL-2 an ti bawk. He damdawi hi eng nge a nih, eng nge a tih, leh i ei huna i hriat tur te han thlir ila.
Aldesleukin hi eng damdawi nge a nih?
A awlsam zawngin Aldase hi cancer damdawi a ni. Mahse, chemotherapy damdawi kan hriat fo ang kha a ni lo. A nihna takah chuan immunotherapy a ni . Chu chu cancer cell-te chu direct-a tihlum ai chuan, nangmah ngeiin i taksa hriselna a tichak a, cancer cell-te do tûrin chakna a pe tihna a ni . Kan taksa chhunga "sipai" (immune cells) te training a, hmêlma cancer an tih do tura tirh ang mai a ni.
He damdawi (brand name: Proleukin) hi a bik takin:
- Renal cell cancer na lo emaw advanced emaw tan chuan .
- Advanced melanoma tan chuan, vun cancer na tak a ni.
A then phei chuan cancer chi dang tan pawh doctor ten he damdawi hi an rawt thei bawk.
Enkawl tan hmaa doctor hnena hrilh tur pawimawh ber berte
He enkawlna hi i tan a tha em tih i rel hmain i doctor hnenah i hriselna chanchin kimchang i hriattir hmasak phawt a pawimawh. A hnuaia dinhmunte hi hrilh ngei ang che, a bik takin:
- Thisen lama harsatna (e.g. thisen zam harsatna, thisen tlakchhamna) i neih chuan.
- I chau emaw i chau emaw i tih reng chuan .
- I taksaah khawsik emaw, hri kai theihna dang emaw i neih tawh chuan.
- Lung, lung, kal leh thin natna eng emaw i neih chuan.
- Immune system lama harsatna dang i neih chuan .
- Rilru natna (e.g. depression) i neih emaw, damdawi i ei emaw a nih chuan.
- Tun hmain organ transplant i lo nei tawh a nih chuan .
- Seizures i neih chuan .
- Pum lama harsatna emaw, chaw ei kawng natna emaw i neih chuan.
- Thyroid lama harsatna i neih chuan .
- Aldesleukin emaw, damdawi dang emaw, ei tur emaw, dye dang emaw allergy i neih chuan .
- Naupai i nih chuan, naupai tum i nih chuan, nu hnute pe lai i nih chuan .
He information hi i himna atan a pawimawh hle a, a chhan chu he information atang hian doctor in i tana enkawlna tha ber leh him ber tur a rel ang.
Engtin nge he damdawi hi pek i nih ang?
Hei hi damdawi in lama hruai theih a ni lo. Aldase hi damdawi in emaw, clinic emaw-ah pek a ni a, doctor leh nurse-te enkawlna hnuaiah pek a ni . A tlangpuiin vein (intravenous emaw IV emaw) chhunga injection angin pek thin a ni. A chang chuan vun hnuaia injection (subcutaneous injection) angin pek theih a ni bawk.
He enkawlna hi damdawi inah pek a nih avangin dose pakhat hloh emaw, overdose emaw lak a ngai lo. Medical team hian nasa takin an enkawl ang.
Accident-a overdose i ei nia i hriat chuan doctor emaw nurse emaw hnenah hriattir nghal rawh. Eng emergency-ah pawh damdawi in Emergency Treatment Unit (ETU) -ah i kal thei a, poisoning lama harsatna i neih chuan Colombo National Hospital-a National Poisons Information Center-ah i call thei bawk.
Damdawi dang i ei laiah fimkhur rawh.
Aldesleukin i ei dawnin i damdawi ei tur dang zawng zawng chu doctor hnenah hrilh vek a pawimawh. Damdawi thenkhat chuan he enkawlna nen hian an inzawm thei a ni. Chuvangin, i la tur a ni:
- Cancer dona damdawi dang (e.g. doxorubicin, methotrexate) .
- Antibiotics, a bik takin aminoglycosides te hi a ni
- Thisen sang damdawi (e.g. beta blockers) .
- Rilru hriselna damdawi (depression, lungkhamna tan) .
- Steroid chi hrang hrang (e.g. prednisone, cortisone) .
- Natna tidamtu, a bik takin NSAID (e.g. ibuprofen, naproxen) te
- Mut theihna damdawi
- Immunosuppressive damdawi dang interferon alfa te pawh a awm bawk
He list bakah hian i doctor hnenah vitamin eng emaw, herbal supplement i ei te, leh zu i in emaw, zu i in emaw te hrilh theihnghilh suh .
Enkawl laia ngaihven bik tur thil
- Continuous monitoring: He enkawlna hun chhung zawng hian doctor leh nurse te chuan uluk takin an enkawl ang che.
- Thisen test: I enkawlna kal zel dan enfiah tur leh side effects hriat hmasak nan thisen test neih fo a ngai dawn a ni.
- Infection laka invenna: He damdawi hian taksain natna a do theihna chu hun eng emaw chen a ti tlem thei a ni. Chuvangin,Khawsik emaw, flu emaw vei te lakah inthiarfihlim tum ang che. Damdawi i ei laiin khawsik emaw, natna hrik i neih chuan mahni invenna nei lo la, doctor hnenah hriattir nghal rawh.
- Harsatna tlangpui: He damdawi ei lai hian tlem a nuam lo emaw, natna emaw a awm hi thil pangngai a ni. Hei hi enkawlnaah hian a tel ve a ni. Mahse, symptom thar emaw, harsatna i neih chuan doctor hnenah hrilh rawh.
Damdawi hian eng side effect nge a neih theih?
Damdawi dang ang bawkin aldesleukin hian side effect a nei thei a ni. Chung zinga ṭhenkhat chu damdawi lam pan vat a ngai a, ṭhenkhat erawh chu a na lo hle thung.
| Side effects awm thei chu doctor/nurse hnenah hriattir nghal tur a ni | |
|---|---|
| Symptom a ni | Hrilhfiahna |
| Allergy na tak a nei | Vun vun rawng, hnim hring, hmai, hmui emaw lei emaw a hring. |
| Thâwk harsa | Thâwk harsa, rilru atanga wheezing sound lo chhuak. |
| Lung lam harsatna a awm | Chhuak na, thinlung thawk chak emaw, mumal lo emaw. |
| Rilru lam inthlak danglamna | Buaina, rilru hah, lungkham, thil tak tak ni lo hmuh leh hriat (hallucinations). |
| Kidney lama harsatna nei | Zun a tlahniam, zun dum emaw, a sen emaw a awm. |
| Liver lama harsatna a awm | Mit leh vun a sen (yellowing) thin. |
| Symptom na tak dang a awm bawk | Luak chhuak nasa, mutthilh, thisen chhuak emaw, hliam emaw, taksa (a bik takin hmai leh ke) hring, hah lutuk, luak chhuak, khawsik, khawsik, kawr na. |
| Thil pawi lo tlangpui, mahse a awm reng chuan doctor hnenah hriattir tur a ni | |
|---|---|
| Bloating (ril\am) 1.1. | Luhai |
| Mutthilh theih lohna | Chaw chakna |
| Kawngkhar natna | Pum natna |
He list-a tarlan loh symptom danglam dang i neih chuan i doctor emaw nurse emaw hnenah pawh hrilh la.
Take-Home Thuchah a ni
- Aldesleukin/IL-2 hi damdawi bik a ni a, cancer cell direct-a tihlum ai chuan, mahni taksa immune system tichaktu hmanga cancer dona atana puitu a ni.
- He enkawlna hi damdawi inah pek a ni a, damdawi lam enkawlna hnuaiah pek a ni a, chuvangin a hman dan tur emaw, damdawi vawn reng tur emaw ngaihtuah a ngai lo.
- Enkawlna i tan hmain i doctor hnenah natna dang i neih leh i damdawi ei tur (vitamin leh herbs te pawh tel) te hrilh hmasa phawt ang che.
- Enkawl laiin side effect na tak tak i neih chuan khawsik, thawk harsa, rilru na, emaw, a hring nasa emaw i neih chuan medical staff te hriattir nghal rawh.
- He enkawlna hi a harsa thei hle a, mahse nangmah chauh i ni lo. I medical team te chuan tanpui turin an inpeih reng a ni. Zawhna leh ngaihtuahna eng emaw an neih chuan sawipui hlau suh.
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