Nangmah emaw, i fa emaw pawh nise, i doctor-in damdawi Alpelisib (brand name: Vijoice) tih chu ei tan turin a hrilh tawh mai thei. Chutiang damdawi bik hming i hriat chuan i rilruah zawhna tam tak a lo lang thin a, chu chu "Hei hian eng nge a tih?", "Engtin nge ka ei ang?", "Eng fimkhur tur nge?" Chuvangin hlau suh. Vawiin hian he damdawi Alpelisib an tih hi chiang tak leh awlsam takin kan sawi dawn a ni.
Alpelisib hi eng damdawi nge ni?
A awlsam zawngin sawi ila, Alpelisib hi taksaa cell thenkhat, a pangngai lo, control theih loha lo thanglian zel tur control tu damdawi a ni. He damdawi hi a bik takin taksa peng thenkhat (entir nan, kut, ke, emaw tissue thenkhat) PIK3CA tih gene-a mutation avanga lian lutuk a nih thinna enkawlna atan hman a ni. He dinhmun hi PIK3CA-related overgrowth spectrum (PROS) kan ti a ni. He damdawi hian chu cell than dan pangngai lo tipungtu signaling pathway chu a block a, chu chuan natna chu a control thei a ni.
I doctor chuan damdawi lam thil dang atan pawh hei hi a pe thei a, chuvangin zawhna i neih chuan i doctor nen sawiho rawh.
Damdawi ei tan hmaa doctor hnena i hrilh tur thilte
I himna tur leh damdawi atanga hlawkna tam ber i hmuh theih nan Alpelisib i ei hmain i doctor hnenah he thu hi hrilh hmasak a pawimawh.
- Zunthlum i neih chuan: Zunthlum i vei tawh emaw, thisen sugar level sang emaw i neih tawh chuan min hrilh ang che.
- Lung natna: Lung natna eng emaw i neih chuan, Asthma emaw Pneumonia emaw.
- Allergy: Alpelisib emaw damdawi dang emaw, ei tur emaw, dye dang emaw allergy i neih chuan doctor hnenah hrilh ngei ang che.
- Naupai: Naupai, nau pai tum emaw, naupai nia rinhlelhna tlemte pawh nei emaw i nih chuan.
- Nu hnute petu i nih chuan: Nausen hnute i pe a nih chuan.
Chung thilte chu doctor-in a hriat chian hunah chuan i tan a inhmeh ber tur enkawlna tur ruahmanna siam chu a awlsam zawk ang.
Engtin chiah nge he damdawi hi ka hman ang?
He damdawi hman dan tur dik tak zawm a pawimawh hle.
- Doctor-in a sawi angin damdawi chu ei la, nitin hun inangah ei rawh .
- He tablet hi cut emaw chew emaw suh . Tablet chu tui nen a pumin ei rawh.
- Damdawi hi chaw ei rualin ei a tha ber .
- I doctor-in chawlhsan tura a tih hma loh chuan damdawi hi ei chhunzawm zel ang che. I rilru a hahdam viau pawhin chawlhsan thut suh.
Pill chu ei harsa a nih chuan engtin nge tih ang?
Mi thenkhat, a bik takin naupang te hian damdawi ei harsa an ti thin. Chutiang a nih chuan, tih dan tur chu hetiang hi a ni:
1. Tablet chu glass-ah tui ounces 2-4 (60-120 ml vel) dah la.
2. Minute 5 vel hnuah tablet chu spoon fai tak hmangin uluk takin chil la, tuiah a hmin hma chu hrual tha rawh.
3. He mixture hi in nghal rawh.
4. Tichuan, glass khatah tui tablespoon 2-3 vel dah belh la, glass chhunga damdawi awm zawng zawng chu silfai la, chu chu in rawh. Hei hi damdawi pakhat mah a bo loh nan ti rawh.
Pawimawh: He damdawi hi naupang kum 2 chunglam tan pawh special case thenkhatah pek thin a ni. Mahse, hei hi i doctor chauhvin a rel thei ang. Chuvang chuan he damdawi hi naupang hnenah i pe dawn a nih chuan doctor thupek hi uluk takin zawm tur a ni.
Damdawi ka ei tam lutuk (overdose) chuan engtin nge ni ang?
He damdawi hi i ei tam lutuk nia i hriat chuan tihkhawtlai suh. Colombo National Hospital a National Poisons Information Center ah phone nghal rawh . A nih loh leh damdawi in hnai ber Emergency Treatment Unit (ETU)-ah kal rawh.
Damdawi dose pakhat i ei loh chuan engtin nge i tih?
Dose i ei theihnghilh chuan i hriatreng veleh ei nghal rawh. Mahse, i hriatreng hunah i dose leh tur thleng darkar 9 aia rei lo (i.e., darkar 9 aia rei a tlai) a nih chuan missed dose chu skip rawh. Dose dang chu a hun ruatah ei mai rawh. Dose hloh tawh chu vawi khatah vawi hnih ei ngai suh.
He damdawi nena inzawm thei damdawi dang (Drug Interactions) .
Damdawi thenkhat i ei hian Alpelisib nen an inzawm thei a, a thatna emaw, a side effect emaw a nghawng thei bawk. Chuvangin, a hnuaia damdawi emaw, supplement dang emaw, vitamin emaw, herbal remedies emaw i ei a nih chuan i doctor hnenah hrilh rawh.
- Epilepsy damdawi hman \henkhat: Entirnan, `(Carbamazepine)`, `(Phenobarbital)`, `(Phenytoin)`.
- `Cyclosporine` tih a ni
- `Eltrombopag` tih a ni
- `Enzalutamide` tih a ni
- `Mitotane` tih a ni
- `Rifampin` (TB natna damdawi) .
- `St. John’s Wort` (rilru hriselna atana thinghnah damdawi) .
- `Sulfasalazine` tih a ni
- `Warfarin` (thisen zawrh loh nan damdawi pek thin) .
He list hi a kim lo a, chuvangin i damdawi ei zawng zawng hi doctor hnenah hriattir vek a tha ber.
Damdawi i ei dawna i fimkhur bik tur thilte
- Damdawi lam enfiah fo: I natna lan chhuah dan a tha lehzual em tih hriat nan doctor hnenah zawt fo thin ang che. Thisen test tul (thisen hnathawh) chu skip suh.
- Vun natna nasa tak: Mi thenkhat chuan he damdawi hi an ei tan atanga kar engemaw zat hnuah pawh vun natna nasa tak an nei thei.Khawsik emaw, khawsik emaw ang chi symptoms te nen rash i neih chuan doctor hnenah hrilh nghal rawh. Heng rashes te hi a sen emaw, purple emaw a lo ni thei a, chutah chuan blister leh peel a ni thei. A nih loh leh i hmai, hmui, kawr emaw, i kawrfual emaw-ah vun sen a awm tih i hriat chuan lymph node hring hring nen i hmu a nih chuan doctor ko nghal rawh.
- Luak chhuak nasa tak leh tui tlakchhamna: Luak chhuak nasa tak, luak chhuak, emaw, thawk hah lutuk i neih chuan i doctor hnenah hrilh rawh . He damdawi ei lai hian i taksa atanga tui tam lutuk (dehydration) hloh hi a hlauhawm thei hle.
- Thisen thlum sang (Hyperglycemia): He damdawi hian thisen thlum a tisang thei. Hetiang hlauhawmna hi zunthlum vei tawhte tan chuan a sang zawk a ni. I doctor hnenah a tlangpui aia tuihal i tih chuan, i zun tam zawk a nih chuan, i chau danglam deuh a nih chuan, a nih loh leh i mit a fiah lo a nih chuan i doctor hnenah hrilh rawh .
- Kawng vawt: Kawng vawt i tawng thei. Hei hi sugar-free gum chewing leh tui tam tak in ang chi thilte hian a thunun thei a ni. Mahse, harsatna a awm reng emaw, a nasat emaw chuan doctor hnenah hrilh rawh.
Naupai chungchanga vaukhânna pawimawh tak: He damdawi ei lai leh damdawi ei chawlhsan hnu kar khat chhung chu naupai kim loh tur. Mipa pawhin he damdawi ei lai leh damdawi an ei zawh hnu kar khat chhung chu fa neih loh tur a ni. He damdawi hian nausen piang lai tan harsatna nasa tak a thlen thei a ni. Hemi chungchang hi doctor zawt la. Tin, he damdawi hi i ei lai leh damdawi i ei zawh hnu kar khat chhung chu nau hnute pek loh tur a ni.
Damdawi avanga side effect lo awm thei
| Side effect a awm thei | Description leh tih tur |
|---|---|
| Side effects te chu doctor hnenah hriattir nghal tur a ni | |
| Allergy natna a awm thei | Vun vun rawng, hnim hring, hmai, hmui, lei emaw kawr emaw a hring. |
| Diarrhea na tak a awm | A tawp theih loh flatulence. |
| Thisen thlum sang (Hyperglycemia) 1.1. | Tuihâl lutuk, zun tam, hah lutuk, mit hmuh fiah lo. |
| Lung hliam a awm | Thâwk harsa, khuh, thisen chhuak phlegm, rilru na, khawsik. |
| Vun natna khirh tak tak | Vun a sen, a hring, a hring (ka chhungah pawh). |
| I doctor hnena hrilh tur thilte chu a awm reng emaw, a buaithlak emaw a nih chuan | |
| Vun a vawt | Vun a vawt |
| Lu na | Lu na |
| Sam tlakchhamna | Sam tlakchhamna |
| Kawng emaw, kawr emaw a na | Natna, sen, emaw, ka chhung emaw, kawchhung emaw chhunga hliam awm |
Engtin nge i damdawi hi him taka i vawn reng?
- Naupang leh ran vulh lakah hla takah dah rawh.
- 20 leh 25 degree Celsius (68-77 Fahrenheit) inkar temperature-ah dah la, chu chu room temperature pangngai a ni.
- Damdawi expired hman loh tur.
- Damdawi hman loh emaw, hun tawp tawh emaw i paih dawnin, a label-ah chuan paih chhuah a him em tih enfiah thin ang che. Ringhlel i neih chuan doctor zawt rawh. Thlawhna atana him a nih chuan, pill chu bottle atang chuan la chhuakin, coffee ground hman tawh, lei, emaw, ui bawlhhlawh ang chi thil nen chawhpawlh la, bag emaw, bawm emaw, khar nghet takah dah la, bawlhhlawh bawmah paih rawh.
Take-Home Thuchah a ni
- Alpelisib hi damdawi bik a nih avangin doctor-in a sawi ang chiah chiah, a hun takah ei fo thin ang che.
- Damdawi dang i ei lai leh i damdawi ei tan hmain i doctor hnenah hrilh hmasa phawt ang che.
- Vun natna nasa tak (khawsik, vun, blisters) leh thisen sugar sang chhinchhiahna (tuihal tam lutuk, zun tam lutuk) te chu fimkhur fo ang che. Thil i hriat chuan doctor hnenah hrilh nghal rawh.
- He damdawi ei lai leh ei zawh hnu kar khat chhung chu naupai kim loh a pawimawh hle.
- He damdawi hi i tan chauh a ni. Midang hnenah share ngai suh.
- Damdawi chungchanga zawhna, ngaihtuahna leh rinhlelhna i neih chuan lo chhut la, i doctor nen direct in inbiakna nei rawh.
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