Lu na i nei fo em? I luak chhuak em? A nih loh leh, i hriatrengna chu a tlahniam zauh zauh ang maiin i hria em, a nih loh leh i thusawi laiin i thusawi chu a hlim lo deuh niin i hria em? Heng thilte hi chhan pangngai vangin thleng thei mah se, a tlem berah chuan thluaka natna lan chhuahna (symptoms) a ni thei. Chuvangin vawiin hian thluak leh ruhroa lo awm tumor chi khat, ‘Astrocytoma’ an tih chungchang kan sawi dawn a ni. Ngaihtuah buai suh, hemi chungchang hi awlsam takin i hrethiam vek ang u.
A awlsam zawngin Astrocytoma chu eng nge ni?
Astrocytoma hi kan central nervous system (CNS) -a lo awm thei a ni a, chu chu thluaka awm a ni ber a, mahse a chang chuan ruhroah a awm thung. Heng tumor te hi kan thluaka arsi ang chi cell chi khat bik ‘astrocyte’ an tih atanga lo piang chhuak a ni. Heng astrocyte cells te hi cell chi khat an ni a, thluaka nerve cell dangte tanpuitu hna thawkin, an chawm a, a venghim bawk. Heng cell te hi thunun theih loha an lo thang lian tan hian astrocytoma tumor a lo awm thin.
A pawimawh ber chu heng Astrocytomas zawng zawng hi cancer an ni vek lo. Ṭhenkhat chu benign tumor an ni. Mahse thenkhat chu cancer (malignant) an ni thei bawk.
Astrocytoma hi thluaka natna chi khat, glioma an tih chu a tam ber a ni.
Astrocytoma chi hrang hrang leh grade hrang hrang a awm em?
Ni e, World Health Organization (WHO) chuan Astrocytoma tumor te hi an than chak dan leh a chhehvel tissue-a an darh theih dan a zirin main grade pali (Grades 1-4) ah a then a. Pawl 1 hi a na lo ber a, pawl 4 hi a na ber leh a darh chak ber a ni.
Hengte hi dawhkan hmangin i hrethiam ang u.
| Pawl | Thuziak leh chi hrang hrang |
|---|---|
| Pawl 1 (Cancer nei lo) 1.1. | Hengte hi benign tumor an ni a, an thang zawi hle a, an darh lo. Surgery hmanga lak chhuah vek a nih chuan enkawlna dang (radiation emaw chemotherapy emaw) a ngai tawh lo tlangpui.
|
| Pawl 2 (Cancer natna) 1.1. | Hengte hi cancer natna hrik an ni. An chhehvel thluak tissue-ah an darh duh hle. Chuvangin, surgery ringawt pawh hi inenkawlna atan a tawk lo mai thei. |
| Pawl 3 (Cancer natna vei) . | Hengte hi grade 2 aiin tumor nasa zawk leh thang chak zawk an ni a, a tam zawkah chuan grade 2 tumor te hi hun kal zelah hetiang dinhmunah hian an kal thei a ni. Surgery ringawt pawh hian a tidam thei lo. Radiation leh chemotherapy hi a ngai tak zet a ni. |
| Pawl 4 (Cancer natna vei) . | Chungte chu glioblastoma an ti bawk . Hei hi astrocytoma chi hrang hrang zingah chuan a na ber, a lo thang chak ber leh a na ber a ni. Puitling zingah thluak cancer chi khat a ni ber bawk. |
He natna hi tuin nge vei tam ber?
Astrocytoma hi kum eng pawhah a lo awm thei a, mahse grade hrang hrang hi kum hrang hrangah a tam zawk.
- Pawl 1: Naupang leh puitling tleirawl zingah a awm fo.
- Grade 2: Puitling kum 20 leh 60 inkar ah a tam ber.
- Pawl 3: Puitling kum 30 leh 60 inkar ah a awm fo.
- Grade 4 (Glioblastoma): Puitling kum 50 leh 80 inkar zingah a awm fo.
Mipa hian astrocytomas na tak (grade 3 leh 4) an nei tlem zawk.
Hei hi eng symptoms nge ni?
Symptoms chu tumor lian leh te leh thluaka a awmnaah a innghat a ni. Thluak peng hrang hrangin kan taksaa hnathawh hrang hrang a thunun avangin, chu tumor chuan chu hmun chu pressure a siam chuan chu peng nena inzawm symptoms chu a lang chhuak thin.
Heng a lan chhuah dan tlangpui thenkhat chu hetiang hi a ni.
| Symptom a ni | Hrilhfiahna |
|---|---|
| Lu na | Zingkar harh veleh lu na tak, natna tidamtu pangngai pawhin a chhang lo. |
| Nausea leh luak chhuak | Chhan bik nei lovin nausea leh vomiting. |
| Seizures a awm thin | Nun chhunga a vawi khatna atana seizure neih. |
| Rilru leh nungchang inthlak danglamna | Hriatrengna hloh, ngaihtuahna seng harsa, mize danglam (thinrim, lungngaih), leh buaina. |
| Taksa lama harsatna | Mit lama harsatna (blurred vision, double vision), tawng harsa (aphasia), taksa sir khata bengchheng emaw chak lo emaw, kal harsat. |
Heng symptoms pakhat emaw, a aia tam emaw a zawna i neih chuan a rang thei ang bera doctor pan rawh.
Astrocytoma hi engte nge ni?
Dik tak chuan astrocytoma tam zawk hi a chhan dik tak chu hriat a la ni lo . Anni hi a chang chuan a thleng fo a, a chhan hriat theih loh. Mahse, zirchiangtute’n an hmuhchhuah risk factor pahnih a awm.
1. Radiation Exposure: Lu-ah, a bik takin naupang laiin, cancer dang tan radiation therapy hmangin naupan laiah astrocytoma vei theihna a tipung thei a ni.
2. Genetic Condition awm lo tak tak:Genetic condition hmuh tur awm lo, inherited genetic condition thenkhat chuan astrocytoma vei theihna a tipung thei a ni. Entirnan:
- Li-Fraumeni natna a ni
- Neurofibromatosis chi khat (NF1) a awm thin.
- Tuberous sclerosis natna a ni
- Turcot natna a ni
Engtin nge natna hi kan hriat theih ang?
Doctor i pan hunah i symptoms te ngun takin a ngaithla hmasa ang a, a enfiah hmasa ang che, a bik takin neurological exam.
Chumi hnuah chuan thluak chhung lam en turin test eng emaw zat nei turin refer i ni mai thei.
- MRI (Magnetic Resonance Imaging) scan: Hei hi thluaka natna hrik hriat chian dan tha ber leh chiang ber a ni.
- CT (Computed Tomography) Scan: He test hi MRI tih theih loh hunah (e.g., pacemaker dah a nih chuan) tih a ni.
He scan hian thluaka thil danglam tak a hmuh chuan biopsy an ti a, chu chu eng tumor chi nge tih chiang takin an hre thei a ni. Hei hian tumor chi hrang hrang surgery hmanga lakchhuah a, microscope hmanga enfiah a ngai a ni. A châng chuan, he tissue hi surgery (resection) ang chiah hian lak a ni a, chu chuan tumor chu a paih chhuak vek a ni.
Enkawlnate chu engte nge ni?
Enkawlna hi thil engemaw zat atanga teh a ni a, chung zingah chuan tumor chi (grade) te, a lian leh te, thluaka a awmna te, i kum te, leh i hriselna zawng zawng te pawh a tel. Neurologist, neurosurgeon leh oncologist te hian enkawl dan tur tha ber tur an siam tlangpui thin.
Enkawl dan tlangpui chu:
1. Surgery tih a ni
A theih phawt chuan surgery hi enkawlna hmasa ber a ni. Hei hian thatna pawimawh tak tak engemaw zat a nei a:
- Tissue sample lak theih a ni a, tumor chi dik tak hriat theih a ni.
- A theih ang anga tumor chu paih chhuakin thluaka pressure i tihziaawm thei.
- Symptoms lo chhuak te chu a reh thei a ni.
Grade 1 astrocytoma tumor te chu surgery hmanga paih vek theih a nih chuan natna hi a dam kim thei a ni.
2. Adjuvant Therapies hmanga enkawlna (Adjuvant Therapies) te
A nasat (grade 2, 3, 4)-ah chuan operation hnua cancer cell la awm zawng zawng tihchhiat nan enkawlna dang pek belh a ngai a ni.
- Radiation Therapy: Cancer cells tihchhiat nan high-energy rays (X-ray ang chi) hman a ni.
- Chemotherapy: Cancer cells thattu emaw, an thanlenna titawp thei damdawi pek. Hemi atan hian `Temozolomide (TMZ)` hi damdawi hman tlanglawn tak a ni.
- Tumor-treating fields: Hei hi hmanraw bik, helmet ang maia bun a ni. Electric field a tihchhuah hian cancer cell te than dan a thunun a ni. Hei hi glioblastoma (grade 4) tan chuan a tha thei ang.
- Bevacizumab hmanga damdawi hman tur:Hei hi vaccine a ni. Tumor-a thisen pe chhuaktu thisen kalna kawng siam a titawp a, tumor thanna tur a control a ni.
He natna hi eng prognosis nge ni?
Natna dam leh damchhuahna rate hi thil engemaw zatah a innghat a ni.
- Tumor grade: Grade a san chuan a natna hi a na zual thei.
- Surgery hmanga lak chhuah theih zat: Tumor tam zawk lakchhuah theih a nih chuan a result a tha zawk ang.
- Kum: Tleirawl zawkte hian result tha zawk an hmu tlangpui.
- Hriselna dinhmun pum pui: Natna hmuhchhuah a nih hunah damlo hriselna dinhmun a tha a pawimawh.
Atlangpuiin,
- Pawl 1: Zai hnu kum 10 aia rei dam theihna a awm.
- Pawl 2: Kum 5 aia tam.
- Pawl 3: Kum 2 leh kum 5 inkar.
- Pawl 4 (Glioblastoma): A tlangpuiin kum khat vel a ni.
Pawimawh: Hengte hi mipui tam tak data atanga average value chauh a ni tih hre reng ang che. Chûngte chu i mimal dinhmun a zirin a danglam thei a ni. Chuvangin, i dinhmun dik ber hriat duh chuan doctor rawn la a tha ber.
Take-Home Thuchah a ni
- Astrocytoma hi tumor chi khat a ni a, thluak emaw, ruhro emaw a awm a ni. Cancer nei leh cancer nei lo chi hrang hrang a awm.
- Hengte hi an nasat dan azirin pawl 1 atanga 4 thlenga then an ni. Grade 1 hi a na lo ber a, grade 4 (Glioblastoma) hi a na ber a ni.
- Lu na fo, luak chhuak, seizure, leh hriatrengna hloh te ang chi symptoms te chu ngaihthah suh. Hengte hi a awm reng chuan doctor pan nghal tur a ni.
- Surgery, radiation therapy, chemotherapy te hi a enkawl dan ber a ni.
- Brain tumor chungchang hriat chu hlauhawm tak ni thei mah se, enkawlna dik leh damdawi lam thurawn i pek chuan i natna lan chhuah dante chu i thunun thei a, i nun chu i kalpui thei a ni. I medical team te chuan tanpui turin an inpeih reng a ni.
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