Nangmah emaw, i chhungte zingah emaw doctor-in thisen tihthianghlimna damdawi a pe tawh em? "Thisen tithianghlimtu" tih hi i hre tawh mai thei. Heng damdawi te hian thisen a ti thim tak tak lo va, thisen zam (clotting process) a control mai a ni. Vawiin hian damdawi class pawimawh tak, Factor Xa Inhibitors tih chu kan sawi dawn a ni.
A awlsam zawngin, heng Factor Xa Inhibitor te hi engte nge ni?
Factor Xa Inhibitors hi damdawi chi khat a ni a, kan thisen zam lutuk tur venna a ni. Doctor te chuan ``Direct Oral Anticoagulants - DOACs'' tiin an sawi thin. A awlsam zawngin sawi ila, hengte hi thisen zam tur venna damdawi an ni. Thisen zam lo awm tawh enkawl nan an hmang a, chubakah nakin lawka thisen zam a awm loh nan hun rei tak enkawlna atan an hmang bawk.
He category-a tel damdawi chi hrang hrang lian tak tak a awm a.
| Ruihhlo Hming | Point bikte chu |
|---|---|
| Apixaban a ni | A hman tlanglawn chi. |
| Rivaroxaban a ni | A hman tlanglawn chi dang. |
| Edoxaban a ni | Damdawi lam thurawn pekna atana hman thin. |
| Fondaparinux a ni | Hei hi pill ni lovin, injection intravenous a pek a ni. |
Hengte hi eng ang damdawi lam dinhmun atan nge hman?
Heng damdawi te hi chhan hrang hrang avangin pek theih a ni a, a bik takin:
- Stroke hlauhawmna tihziaawm: A bik takin atrial fibrillation nei tan, thinlung atria-a heartbeat mumal lo nei tan.
- Vein-a thisen zam (Venous Thrombosis) awm theihna a tihziaawm.
- Lung leh thisen kalna lam natna nei, coronary artery disease leh peripheral artery disease nei te zingah cardiovascular events awm theihna tihziaawm.
- Vein thuk takah thisen zam (Deep Vein Thrombosis - DVT) enkawl. Hei hi keah a awm tlangpui.
- Lung chhunga thisen zam (Pulmonary Embolism - PE) enkawl.
- Venous thromboembolism (VTE) enkawl tur a ni.
He damdawi hi tuin nge ei tur?
Mi thenkhat chuan heng damdawi te hi thisen zam an neih tawh avangin an ei thin. Mi dangte tan chuan thisen zam vei an hlauhawm avangin doctor-te chuan invenna atan an pe thin.
Mi pakhatin total hip replacement a nei tawh ang tih han ngaihtuah teh. Surgery zawhah hian khumah rei vak lo i awm a ngai a, chuvangin i ke vein-a thisen kal chu a tlahniam a, thisen zam theihna a tipung a ni. Chutah chuan doctor ten heng damdawi te hi an rawn pe thin. Khup thlak hnuah pawh pek an ni bawk.
Damdawi hlui Warfarin leh he damdawi thar hi eng nge an danglamna?
Factor Xa Inhibitors lo chhuah hma khan thisen zam venna atana hman tlanglawn ber chu ``Warfarin.`` Warfarin hi damdawi tha tak a ni a, kum tam tak chhung chu hman a ni tawh a.
Mahse hei hi a danglamna ber chu a ni : Warfarin ei thin chuan damdawi dose a thawk tha em tih hriat nan thisen test (INR test) neih fo a ngai a ni . He test hi kar khatah vawi hnih tih theih a ni a, thla khatah vawi khat tih theih a ni bawk.
Mahse Factor Xa Inhibitors ei thin chuan heng thisen test fo hi a ngai lo tlangpui. Nitin a prescribed dose ei hi a tawk. Hei hi damlo tan chuan awlsamna ropui tak a ni.
He damdawi hian taksaah engtin nge hna a thawh?
Hei hi hriatthiam a awl hle mai. Kan taksaa thisen zam (blood clot) siam dan hi factory-a assembly line angin han ngaihtuah teh. Step tam tak inzawmkhawm a awm a.
He production line-ah hian "Factor Xa" hi hnathawk pawimawh tak a ni. A tel lo chuan a dawt leh turah kan kal thei lo. Chuvangin, he Factor Xa Inhibitor damdawi hmanga kan tih chu chu hnathawk (chu chu protein) "Factor Xa" tia koh chu hnathawh lohna tura tihtawp hi a ni. Tichuan production line chu a chanve vel a tawp a, chu chu thisen zam chu a lo awm tawh lo tihna a ni. A awlsam hle mai, a dik em?
He damdawi hi eng chen nge ka ei a ngaih?
He damdawi hi i pek chhan hian eng chen nge i ei tur tih a hril ang. I doctor chuan hei hi a hrilhfiah ang che. Hei hi eng chen nge a daih dawn tih chu a ni tlangpui.
| Condition/A chhan | Damdawi ei hun chhung average |
|---|---|
| Thinlung thawk mumal lo (Atrial Fibrillation) . | Nun chhung zawngin vawi tam tak. |
| Thisen zam (VTE) . | Thla 3 atanga thla 6 chhung a ni. |
| Kea thisen zam (DVT) emaw lung (PE) emaw . | Thla 6 vel a ni. |
| Khup thlak surgery hnuah | Ni 12 vel a ni. |
| Hip thlak surgery hnuah | Ni 35 vel a ni. |
Risk leh side effect lian ber berte chu engte nge ni?
Heng damdawi te hi a hlauhawm ber chu thisen chhuah tam lutuk hi a ni . Hei hi thil pangngai a ni a, a chhan chu heng damdawi te hian a tum ber chu thisen zam tihtawp hi a ni. Chumi awmzia chu hliam tenau tak pawh hian a tlangpui aia tlemin thisen a chhuah tam thei tihna a ni. A hlauhawm ber chu thluak chhungah emaw, chaw ei kawngah emaw thisen chhuah hi a ni.
A pawimawh ber chu he damdawi hman lai hian accident leh hliam tuar lo turin a theih ang anga fimkhur hi a ni.
Side effect dangte chu:
- Taksaah awlsam taka hliam (bruising) a awm.
- Vun a hring chhuak.
Heng damdawi te nghawng tidanglam thei tur `(Andexanet Alfa)` ang chi damdawi bik awm mahse, a man to a, damdawi in tinah a awm lo mai thei. Chuvangin fimkhur a tha ber.
Fimkhur tura i tih theih thilte
- Huana hnathawh hunah kutkawr leh pheikhawk bun tur a ni.
- Thil hriam tak tak, chemte leh scissors hman hunah fimkhur hle ang che.
- Bladed razor hmang lovin electric razor hmang zawk rawh.
- I in chhunga slip leh fall hlauhawm (e.g. loose rugs) awm thei te chu hre reng ang che. An hnen atanga accident thlen theihna tur tihtlem.
Doctor hmuh nghal hun tur
A hnuaia symptoms te hi i neih chuan doctor ko nghal rawh. Thil engemaw takah chuan damdawi in hnai ber Emergency Department (ETU) pan a pawimawh .
- Thisen chhuak nasa tak, tihtawp theih loh (e.g. hnar, hmui, hliam atanga chhuak).
- Tlu emaw, lu-a vuak na tak emaw (pawn lam thisen chhuak lo pawh ni se).
- Lu na nasa tak emaw, rilru na emaw.
- Thâwk harsa.
- Vunah hian a danglam bik hle.
Heng damdawi te hian mi tam tak chu thisen test fo thinna atanga chhuah tir a ni a, Warfarin ei thin damlote hman thin ang chi hi a ni. Mahse, heng damdawi te hi mi zawng zawng tan a tha lo. Chuvangin i doctor nen inbia la, eng damdawi nge i tana tha ber tih rel rawh. Eng damdawi pawh ei la, i doctor thupek dik tak zawm a pawimawh a, i hriatthiam loh thil a awm a nih chuan chiang zawka dil a pawimawh.
Take-Home Thuchah a ni
- Factor Xa inhibitor hi thisen zam hlauhawm tak siam tur venna atana hmanraw pawimawh tak a ni.
- Dose dik tak, a hun takah, i doctor-in a tih angin ei fo ang che. Damdawi ei kha bansan ngai suh la, nangmah chauhin a dose pawh thlak ngai suh.
- He damdawi hian a thatna lian tak chu Warfarin angin thisen test fo a ngai lo.
- A hlauhawm ber chu thisen chhuah a nih avangin hliam tuar lo turin fimkhur fo ang che.
- Thisen chhuah dan pangngai lo, lu na na tak, rilru na, emaw, tlu avanga lu hliam emaw a awm chuan damdawi lam pan nghal emaw, damdawi in hnai ber Emergency Department (ETU) pan emaw a ni ang.
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