I thinlung electrical system-ah harsatna a awm em? Long QT Syndrome (LQTS) chungchang hi han sawi ila.

Thinlung electrical system chungchang hi i hre tawh em? Kan thinlung hian machine te tak te ang maiin hna a thawk a. Electrical system a nei a, chu chuan heartbeat a control a ni. A châng chuan, he electrical system-ah hian danglamna tenau tak tak a awm thei bawk. Chutiang inthlak danglamna pakhat chu Long QT Syndrome, a nih loh leh `(Long QT Syndrome - LQTS)` an ti a. Ngaihtuah buai suh, he thu hi awlsam takin sawi ila.

Long QT Syndrome hi eng nge ni? A awlsam zawngin...

I thinlung vawi khat a na hnuah, battery recharging ang maia a thawk leh theih nan "chawlhna" tlem a mamawh tih han ngaihtuah teh. "Recharge" emaw recharge emaw hun chhung hi a tlangpui aia rei deuh a ni a, chu chu long QT syndrome kan tih chu a ni.

ECG i neih tawh chuan, chu chu thinlung electrical activity enfiahna test a ni a, a then chu QT interval an tih a awm a. Hei hian i thinlung hnuai lam, ventricles tia koh te chu eng chen nge a contract a, chutah chuan a relax a, a nih loh leh ka sawi tawh ang khan "recharge" a nih theih nan hun rei tak a mamawh tih a tilang a ni.

Kan thinlung electrical activity hi electric charged particle te tak te `ions` an tih te hian a pui thin. Hei hi sodium, calcium, potassium, leh chloride te ang ion te hian an thawhhlawk hle. Heng ion te hi thinlung cell chhungah hian kawng bik `ion channels` an tih hmangin an lut leh chhuak thin. Tunah chuan he `(Long QT Syndrome)`-ah hian heng ion channel-te hi harsatna a awm emaw, a tlakchham emaw a ni. Tichuan thinlung chu "recharging" ah a tlai ta a ni. QT interval a rei chuan heart rhythm disorder hlauhawm tak, `Torsades de Pointes` an tih, nunna atana hlauhawm tak a awm theihna a sang hle.

Long QT Syndrome chi hrang hrang a awm em?

Ni e, chi hnih a awm. Pakhat chu inherited , chu chu genes hmanga inthlunzawm tihna a ni. The other is acquired , chu chu thil dang, damdawi thenkhat avanga lo awm tihna a ni.

Pianpui chi hrang hrang: 1.1.

Hengte hi ka sawi tawh `ion channels`-a genetic defects vang a ni ber.

• Ion channel abnormalities: Hei hi a tam ber chi a ni. `LQT1, LQT2, LQT3, LQT4, LQT5` te hi chi hrang hrang a awm a. Chungte chu ion channel chi hrang hrang inrawlh dan azirin an thliar hrang a ni. Nakin lawka thinlung natna vei theihna hi a chi hrang hrangah a inang lo thei.
• Jervell leh Lange-Nielsen Syndrome: Hetiang dinhmunah hian nu leh pa pahnih hian gene pangngai lo chu an keng thei a, mahse symptom an nei lo mai thei. Hei hi thil awm lo tak a ni. Nu leh pa pahnih hian gene hi an keng tel a rinawm loh avangin naupang tin hian rochun theihna chance 25% an nei a ni. Hetiang syndrome vei te hi bengchheng lo piang an ni thei.
• Romano-Ward Syndrome natna vei te hi:Hetiang a nih chuan nu leh pa pakhat hian ``Long QT Syndrome'' a nei tlangpui a, pakhat zawk chuan a nei lo. Naupang tin hian he gene danglam tak hi an rochun theihna chance 50% an nei vek a ni. Hetiang a nih chuan hriatna hi thil pangngai a ni.
• Timothy Syndrome: Hei pawh hi a tlem hle bawk. Thinlung chauh ni lovin, taksa peng dangte pawh a nghawng thei a ni.

Hetiang dinhmun hi engtiang chiahin nge a awm?

Long QT Syndrome hi a takah chuan thil awm lo tak a ni . Entirnan, United States-ah chuan mi 2,000 zinga pakhat velin he natna hi an vei nia chhut a ni.

Long QT Syndrome natna lan chhuah dan chu engte nge ni?

Hengte hi a symptom hmuh fo thinte chu a ni:

• Syncope: Thil hriatna hloh nghal mai.
• Seizures: Mi thenkhat chuan seizures an nei thei.
• Cardiac arrest: Hei hi a hlauhawm hle.
• Thihna thut:

Heng symptoms te hi a hmaa ka sawi tawh `Torsades de Pointes` tia koh heart rhythm disorder hlauhawm tak a lo awm hian a lo lang thin. Hetih lai hian thinlung hian thisen a pump tha thei lo. Thluak hian thisen a dawn tawk loh chuan muthilh leh seizure ang chi thil a awm thin. Hetiang natna hi a awm chhunzawm zel chuan thihna rapthlak tak a thleng thei a ni. Mahse, heart rate chu a pangngaia a lo kir leh chuan a symptoms te chu a reh ta a ni.

Symptoms hi a lan tam ber chu:

• Exercise i tih laiin (a nih loh leh exercise i tih hnu minute engemaw zat).
• During strong emotional stimulation , a bik takin hlauthawng emaw, mangang emaw a nih chuan.
• Mut lai emaw, harh nghal mai emaw pawhin .

Pawimawh tak chu Long QT Syndrome vei zinga 50% thlengin symptoms an nei ngai lo mai thei . Tin, mi sawm zinga pakhat vel tan chuan cardiac arrest hi he natna chhinchhiahna hmasa ber a ni. Hei hi enkawl vat loh chuan thihna thlen thei a ni.

A lan chhuah dan hi puitling tirh lamah a intan tlangpui . Symptoms i neih chuan a lo lang leh thei. Kum 30 an tlin hmaa symptoms hi a lang tam ber a, mahse mi thenkhat chuan kum 50 leh a chunglam ah symptoms an nei thei.

Eng thilin nge Long QT Syndrome hi a thlen?

Ka sawi tawh ang khan, hei hi i nu leh pate hnen atanga rochun (congenital) emaw, damdawi thenkhat avanga i neih emaw theih a ni . Long QT Syndrome ah hian i ion channels te gene code ah thil danglam tak a awm a. Heng ion channel pangngai lo te hian i heart rate recovery phase a tikhawtlai a ni. Hei hian nunna atana hlauhawm arrhythmia a thlen thei a ni.

Damdawi thenkhat hian an ion channel-a predisposition engemaw tak nei te chu ``Long QT Syndrome'' a thlen thei a ni. An hre lo pawh a ni mai thei, mahse chutiang damdawi an ei lai chuan ``Long QT'' a lo awm thin.

Acquired long QT syndrome thlen thei damdawi te:

• Ṭhenkhat `Antiarrhythmics` (thinlung rit lam natna damdawi) .
• Antidepressant thenkhat
• Diuretics ( zun tamna damdawi) thenkhat .
• Antibiotics thenkhat
• Serotonin receptor inhibitor emaw antagonist emaw a awm thei
• Histamine receptor dotu a ni

Acquired long QT syndrome thlentu dangte chu:

• Poison chi thenkhat
• Anorexia nervosa (rilru natna, anorexia nena inzawm) .
• Ṭhenkhat `bradyarrhythmias` (thinlung chak lo tak tak) .
• Taksaah hian calcium, magnesium, potassium a tlem
• I nervous system a hliam

He natna hi tute nge vei theihna chance sang zawk?

A hnuaia mite hi ``Long QT Syndrome`` vei theihna chance sang zawk an ni:

• Naupang pian tirh atanga bengngawng tan.
• Naupang leh thalai chhungkaw chanchin sawifiah theih loha thih thut emaw, muhil (syncope) emaw nei te.
• Thisen chhungte ``Long QT Syndrome`` nei tan.
• `Cardiomyopathy` (thinlung ruh natna) emaw pianpui thinlung natna nei tan.
• Damdawi lam thil dang avanga taksaa electrolyte thenkhat awm tlem te tan.
• Thinlung chhunga ion channel tichhe thei damdawi ei thinte tan.

Long QT Syndrome pawh ka test tur em ni?

Long QT Syndrome hi genetic condition a ni a, thlah khat atanga thlah dangah a kai darh thei a ni. I chhungte zinga pakhat (nu leh pa, unau, fate) zinga pakhatin Long QT Syndrome a neih chuan genetic screening neih hi a tha hle ang

First-degree chhungte (unau, nu leh pa, leh fate) zawng zawngte chuan ECG an nei vek tur a ni. Chhungkaw history-a seizures emaw fainting nei tawh tan pawh he test hi neih a pawimawh hle.

A hmasa ber atan chuan i chhungte hian he natna hi an nei tih doctor hriattir hi a ni. I thinlung enfiah nân test ṭûl tak tak a ti ngei ang. Chu test-te chuan he natna hi i nei tih a nemnghet a nih chuan Long QT Syndrome hre chiang tak cardiologist i pan tur a ni.

Long QT Syndrome hian eng harsatna nge a thlen?

``Long QT Syndrome`` hian ka sawi tawh ``Torsades de Pointes`` tih hming pu nunna atana hlauhawm arrhythmia a thlen thei a ni. Hei hian thihna rapthlak tak pawh a thlen thei a ni.

Engtin nge Long QT Syndrome hi hriat theih?

Doctor ten Long QT Syndrome hi ECG test awlsam tak hmangin an hre thei a ni. He natna hi hriat chian nan ECG-a QT interval an teh thin. I QT interval chu millisecond 450 aia rei a nih chuan Long QT Syndrome i nei thei.

I doctor chuan heng thilte hi a zawt ang che:

• Chhungkaw zingah ``Long QT Syndrome'' vei an awm em?
• Chhungkaw chanchin sawifiah loha muhil, rilru hahna, emaw, thinlung lam harsatna emaw a awm em?
• A bîk takin exercise i neih laiin i rilru a buai a, i rilru a buai a, i rilru a buai ngai em?

Long QT Syndrome hriat theihna atan eng test nge hman thin?

ECG bakah hian heng test te hi tih theih a ni bawk:

• Thisen test a ni.
• Genetic testing neih a ni.
• Exercise stress test neih a ni.
• Ambulatory monitor: Hei hian ni engemaw zat chhung chu i thinlung hnathawh dan a enfiah thin.

Engtin nge Long QT Syndrome hi enkawl a nih?

Long QT Syndrome avanga natna lan chhuah dan control thei leh thihna rapthlak tak venna tur damdawi, device emaw surgery emaw a awm. Heng enkawlnate hian natna hi a tidam kim thei lo nain, thinlung thawk dan pangngai lo lakah a venghim thei che a ni.

Damdawi chi hrang hrang

Long QT Syndrome vei tam tak (symptom nei lo pawhin) beta-blocker, nadolol ang chi hi an ei thin. Damdawi dangte hian i QT interval a ti tawi thei a, i electrolyte level a ti tha thei bawk. I doctor chuan eng damdawi nge i tana tha ber tih a hrilh ang che.

Device hrang hrang te

``Long QT Syndrome'' vei thenkhat pawhin heng ang device hi an mamawh thei bawk:

• Implantable Cardioverter Defibrillator (ICD): Implantable cardioverter defibrillator (ICD) hi cardiac arrest nei tawh emaw, beta-blocker hmanga enkawl ni mahse symptomatic la nei emaw tan dah theih a ni. He device hian nunna atana hlauhawm arrhythmias a hmuchhuak a, automatic-in thinlungah shock a thlen a, chu chuan thihna rapthlak tak a veng thei a ni.
• Pacemaker: He device hian heart rates hniam tak tak nei te chu a pui thin.

Inzai

Long QT Syndrome vei thenkhat chu Left Cardiac Sympathetic Denervation (LCSD) emaw sympathectomy emaw tih a ngai mai thei. Hei hi minimally invasive procedure a ni a, i sympathetic nervous system-a nerve thenkhat chu lakchhuah a ni.

Enkawlna avanga harsatna/side effects awmte chu engte nge ni?

Side effect emaw complication emaw awm thei chu i enkawlna chi hrang hrangah a innghat a ni.

• Beta-blocker hmanga siam a ni:
• Thisen sang hniam.
• Luak chhuak thei.
• Lu na .
• Chau.
• ICD (Cardioverter Defibrillator dah theihna):
• Device tihsual a awm.
• Lung a tlakbuak.
• Thisen chhuak.
• Infection awm thei te.
• Pacemaker hmangtu:
• Lung a tlakbuak.
• Thisen chhuak.
• Infection awm thei te.
• Device tihsual a awm.
• LCSD (Left Cardiac Sympathetic Nerve tihziaawmna operation):
• Horner natna a ni.
• Lung a tlakbuak.
• Hmai sen emaw, thawk hah emaw.

Long QT Syndrome hi a veng thei ang em?

I nu leh pa hnen atanga i rochun chuan i dang thei lovang. Mahse, rochun lo tan chuan a hnuah acquired (long QT syndrome) thlentu condition te hi i veng thei ang. Entirnan, damdawi thenkhatah fimkhur hle ang che.

Long QT Syndrome ka neih chuan eng nge thleng ang?

Enkawlna dik tak pek a nih chuan , ``Long QT Syndrome`` vei te thihna rate hi 1% vel a ni. Enkawlna tel lo chuan dinhmun a chhe hle. Symptoms nei zinga 21% vel chu enkawlna dawng lote chu syncope an neih tan atanga kum khat chhungin an thi thin.

Mahse hre reng ang che, ``Long QT Syndrome'' vei te hian nun pumhlum an hmang thei . Nau an pai thei a, fa an hring thei bawk.

Long QT Syndrome hi eng chen nge a awm?

Inherited Long QT Syndrome hi dam chhung zawnga natna a ni. Mahse, hun kal zelah symptoms leh complication awm theihna a tlahniam thei.

Engtin nge ka in enkawl ang?

Long QT Syndrome hian nitin nun kawng tam tak a nghawng thei a ni. Thil engemaw i tih hmain doctor rawn hmasa phawt tur a ni.

Thawm leh stress

Long QT Syndrome vei thenkhat chu thawm ri nasa tak emaw, emotional stress emaw hian a nghawng thei a ni. I chhehvela thawm leh lungkham zawng zawng i thunun theih loh laiin, tihtlem i tum thei a ni.

• I thiante leh chhungte hrilh la, rang taka kaihthawh che chu a him lo tih hrilh rawh.
• Vawi khata alarm ri nasa tak ri ai chuan ri nuam tak nei alarm hmang zawk ang che.
• I tithinur thei thil ri ring tak takte chu tihhniam rawh.

Insawizawi

Long QT Syndrome chi thenkhat chuan exercise lamah harsatna a thlen tam zawk. I doctor chuan eng thiltih nge i tana a remchang tih a hrilh ang che, chu chu i gene pangngai lo chi hrang hrang a zirin a ni. Exercise hian thihna thlen thei arrhythmias a thlen theih avangin, competitive sports khelh i tum hmain i doctor nen inbiakna neih hmasak phawt tur a ni. Infiamna khelh i tum a nih chuan himna atana fimkhurna engemaw zat i neih a ngai mai thei.

``Long QT Syndrome'' vei thenkhat tan chuan tui chawi hi a hlauhawm thei hle. Tui chawi laiin i muhil a nih chuan tuiah i pil thei a ni.

Damdawi chi hrang hrang

Damdawi tam tak hian QT interval a ti rei thei hle. Heng damdawi te hian ``Long QT Syndrome`` nei te chu a nei lo te aiin a nghawng nasa zawk thei a ni. ``Long QT Syndrome`` i neih chuan a hnuaia mi ang hian i ti tur a ni:

• I doctor zawng zawng hnenah ``Long QT Syndrome'' i nei tih hrilh rawh.
• Damdawi dang damdawi i ei hmain i doctor nen inbiakna nei hmasa phawt ang che.
• Doctor nen inbiakna nei lovin over-the-counter (OTC) damdawi (plain aspirin emaw paracetamol emaw tih loh chu) ei loh tur a ni.

``Long QT Syndrome'' i neih chuan heng damdawi chi hrang hrangte hian a nghawng thei che a ni:

• Antihistamines (allergy natna damdawi) .
• Antidepressants (depression damdawi) 1.1.
• Rilru lam harsatna nei damdawi
• Lung natna damdawi
• `Antibiotics` tih a ni
• Antifungals a ni
• `Antivirals` tih a ni
• Intestinal natna damdawi
• Anticonvulsants a ni
• Diuretics ( zun tamna damdawi) .
• Thisen sang damdawi
• Migraine natna damdawi
• Cholesterol tihhniamna damdawi

Engtikah nge ka doctor ka hmuh ang?

I natna lan chhuah tirh leh chumi hnuah kum khatah vawi khat tal doctor i pan tur a ni. Electrophysiologist hi a tha ber a ni.

I fain ``Long QT Syndrome'' a neih chuan kum khatah vawi khat aia tam doctor i pan tur a ni a, tuna an rih zawng ang chiah hian damdawi dose dik tak an dawng em tih i enfiah tur a ni.

Device implant i neih chuan kum khatah vawi khat doctor i pan tur a ni a, a thawk tha em tih i enfiah tur a ni.

Engtikah nge Emergency Treatment Unit (ETU) ah ka kal ang ?

Cardiac arrest nei chuan damdawi lam pan vat a ngai a ni . A bul hnaia mi pakhatin CPR (cardiac resuscitation) a tan tir tur a ni a, 911 (or i awmna hmuna emergency number) ah call tur a ni.

Doctor hnenah eng zawhna nge ka zawh ang?

Doctor i zawh theih tur zawhna thenkhat chu:

• Eng ang ``Long QT Syndrome'' nge ka neih?
• Eng enkawlna bik nge ka tan i rawt?
• Engzat nge hmuh che ka mamawh?
• Ka ``Long QT Syndrome'' chi bik nen hian eng damdawi leh thiltih nge ka pumpelh tur?

A tawp berah chuan Take-Home Message kan rawn thawn leh ta

Lung natna i nei tih i hriat chuan lungkhamna i neih hi thil pangngai a ni. Mahse i doctor zawhna zawh a, a tul chuan counselor nena inbiakna neih hian i rilru a hahdam zawk thei a ni. Doctor thupek zawm a pawimawh a, a hun taka damdawi ei a, i appointment pawh zawm a pawimawh.

Long QT Syndrome i vei tih i chhungte leh i thiante hriattir chu hahdamna a ni thei bawk. I bula an awm laiin symptom i neih chuan emergency help an ko thei a ni. Chu aia tha zawk chu CPR tih dan an hriat chuan i nunna a chhanhim thei a ni. Lungngai suh, inrelbawlna mumal tak nen chuan nang pawhin nun hrisel i hmang thei ang.

` Long QT Syndrome, LQTS, lung natna, QT interval, thinlung chakna, arrhythmia, genetic natna