Nangmah emaw, i chhungte zinga mi emaw cancer enkawlna i tan tirh hian i doctor-in damdawi a pekte chu tlem a hlauthawng leh hriat duhna i neih chu thil pangngai a ni. Damdawi thar i tan dawnin hriat chian a pawimawh. Chuvangin vawiin hian chutiang cancer dona damdawi bik pakhat, Lorlatinib chungchang kan sawi dawn a ni. I thianpain a hrilhfiah che ang maiin awlsam takin sawi ila.
Lorlatinib chu eng nge ni?
A awlsam zawngin sawi ila, lorlatinib hi chemotherapy damdawi pangngai a ni lo. "Targeted therapy" angin hna a thawk a ni. Hei hian cancer cell te tihpunna tura puitu protein bikte chu direct-in a target tihna a ni. Chutianga a tih chuan cancer cells te chu a tipung thei lo.
"Non-small cell lung cancer" tih natna enkawlna atan hman a ni ber. I doctor chuan he damdawi hi natna dang atan pawh a pe thei bawk. Hemi chungchanga zawhna i neih chuan doctor zawt la.
Damdawi ei tan hmaa doctor hnena hrilh tur thil
I doctor-in he damdawi a pek hma hian i damdawi lam natna dang i neih theih zawng zawngte chu chiang taka hriat a pawimawh hle. He damdawi hian chutiang dinhmunte nen chuan a inzawm thei a ni. Chuvangin, a hnuaia dinhmunte hi i neih chuan doctor hnenah hrilh ngei ngei tur a ni .
- Zunthlum (thisen sugar sang) .
- Thisen sang a sang
- Cholesterol sang tak a ni
- Heart rhythm mumal lo emaw, thinlung natna emaw
- Kal natna
- Lung natna emaw, lung natna emaw
- Rilru natna eng pawh
- Seizures ang chi dinhmun
- Mahni inhriatthiam lohna tur ngaihtuahna te, mahni intihhlum tumna te, chutianga tih tumna emaw, chhungkaw member pakhatin a tih tum emaw
- Naupai tum emaw, naupai mek emaw
- Naute hnute pek
- Lorlatinib emaw damdawi dang emaw, ei tur emaw, dye dang emaw allergy nei tawh
Engtin chiah nge he damdawi hi i hman?
He damdawi hman dan tur dik tak zawm hi result atan a pawimawh hle.
- He pill hi doctor-in a sawi ang chiah hian ei la, nitin hun khatah ei rawh .
- Tablet chu tikehsawm suh, tikehsawm suh, chew suh . Tui nen a pumin ei rawh.
- Chaw ei hma emaw ei zawhah emaw i ei thei a, mahse pum na i neih chuan chaw ei ruala ei a tha ber.
- I doctor-in chawlhsan tura a tih hma loh chuan he enkawlna hi hmang chhunzawm zel ang che.
- A pawimawh hle mai:He damdawi hi i ei lai hian grapefruit tui in vek loh tur a ni .
Dose a sang lutuk a nih chuan engtin nge ni ang? (Overdose) a ni.
Damdawi i ei tam lutuk nia i hriat chuan Emergency Department (ETU) hnai ber pan nghal rawh . A nih loh leh Colombo National Hospital-a National Poisons Information Center-ah thurawn dil turin phone la.
Damdawi dose i ei loh chuan engtin nge i tih ang?
Dose i ei theihnghilh chuan i hriatreng veleh ei nghal rawh. Mahse, i dose leh tur thleng darkar 4 aia rei lo a nih chuan missed dose kha skip rawh. Dose dang chu a hun ruatah ei mai rawh. Double dose ei ngai suh .
He damdawi nena inzawm thei damdawi dang
Lorlatinib hi damdawi dang nena inzawmna nei tha tak a ni. Chuvangin i damdawi ei zawng zawng (vitamin, herbal remedies, leh herbal teas te pawh tel) i doctor hnenah i hrilh tur a ni. A hnuaia damdawi te nen hian a inzawm thei a ni:
| Hengte hi lorlatinib nen ei ngai suh. | |
|---|---|
| apalutamide, enzalutamide, mitotane, ranolazine te a awm bawk | Cancer leh lung natna chi hrang hrang tan damdawi pek thin |
| Antiepileptics damdawi te chu carbamazepine, phenytoin, phenobarbital te an ni | Seizures damdawi hman tur |
| rifampin, rifapentine tih a ni | Tuberculosis ang chi bacteria infection tan antibiotics hman tur a ni |
| Mithianghlim Johana Wort | Depression tan chuan herbal supplement a ni |
| lumacaftor tih a ni a; ivacaftor tih a ni | Cystic Fibrosis natna damdawi hman dan |
| Hengte hi i chhang let thei - i doctor zawt rawh. | |
| Antibiotics damdawi a ni | Ex: clarithromycin hman a ni |
| Antifungals a ni | Entirnan: ketoconazole, itraconazole, fluconazole te hi a awm a |
| HIV leh hepatitis damdawi te | Ex: ritonavir, boceprevir tih te hi a awm a |
| Hormone leh nau neih dan tur | Thil chi hrang hrang, naupai venna damdawi, patch, injection, etc. |
| Damdawi dang | bosentan, modafinil, midazolam tih te hi a ni |
Damdawi ei huna hriat reng tur thil
Cancer enkawl lai hian harsatna engemaw chen hriat hi thil pangngai a ni a, cancer cell leh cell hrisel te a nghawng vek avangin. Mahse doctor-in a tih hma loh chuan enkawlna chu titawp suh. Side effect a awm chuan doctor hnenah hrilh rawh.
Naupai, nau hnute pek leh mipa thurawn
He section hi a pawimawh hle. Uluk takin lo ngaihven rawh u.
- Hmeichhia tan: He damdawi ei lai hian naupai kim loh tur . Tin, damdawi ei chawlhsan hnu thla 6 chhung chu naupai loh tur a ni. Naupai venna atana hormone tel lo (e.g., condom, copper T) hmang rawh. Naupai nia rinhlelhna i neih chuan i doctor hnenah hrilh nghal rawh. Damdawi ei lai leh damdawi ei ban hnu ni 7 chhung chu hnute pek loh tur a ni .
- Mipa tan chuan:He damdawi ei thin mipa te hian naupai thei hmeichhia nen sex an hman hian condom an hmang tur a ni . Hetiang naupai ven dan hi damdawi ei a chawlhsan hnuah thla 3 chhung chhunzawm zel tur a ni. I kawppui naupai nia i rinhlelh chuan doctor hnenah hriattir nghal rawh.
Infection leh khawsik te
He damdawi hian i taksa taksa hriselna a tichak lo thei a, natna hrik i vei theihna a tipung thei bawk. Chuvangin, khawsik, khawsik, ril na, khuh ang chi symptoms i neih chuan mahni indam lo la, doctor ko nghal la , thurawn dil rawh. Damlo laka inthiarfihlim tum ang che.
Cholesterol leh sugar level a awm
Lorlatinib hian thisen cholesterol (a bik takin triglycerides) leh thisen sugar level a tisang thei a ni. Cholesterol tha (HDL) a tihniam thei bawk. I doctor chuan hengte hi a enfiah fo ang. A tul chuan ei leh in thlak danglam emaw, damdawi thar emaw an rawt thei bawk.
Rilru hriselna lama inthlak danglamna
He damdawi hian mi thenkhat rilru lamah a nghawng thei a ni. Nangmah emaw i chhungte emaw chuan a hnuaia inthlak danglamna te hi i hriat chuan i doctor hnenah hrilh nghal rawh:
- Depression thar emaw, zual zel emaw
- Mahni inhriatthiam lohna tur ngaihtuahna
- Hlauhthawnna
- Hriatrengna hloh
- Thil danglam, tibuai thei thiltih emaw ngaihtuahna
Eng side effect nge hmuh theih?
Damdawi dang ang bawkin lorlatinib hian side effect a nei thei a ni. Chung zinga ṭhenkhat chu a pawi thei hle a, report nghal tur a ni.
| Side effects te chu doctor hnenah hriattir nghal tur a ni | |
|---|---|
| Allergy natna a awm thei | Vun vun rawng, hnim hring, hmai, hmui emaw lei emaw a hring |
| Chest na emaw tightness emaw a awm | Heart attack chhinchhiahna a ni thei bawk |
| Khuh, thawk harsa, taksa na (edema) . | A taksa rihna a pung nghal a, ke ruh, kut leh ke a hring chhuak |
| Liver chhiatna chhinchhiahna | Dark yellow emaw brown urine, mit/vun sen, pum dinglam chunglam na |
| Hri kai theihna chhinchhiahna | Khawsik, khawsik, ril na |
| Thisen cell count tlahniam chhinchhiahna | Thâwk harsa, hah lutuk, muthilh, lu hah |
| Rilru inthlak danglamna emaw, epilepsy emaw | A chunga rilru lam chhinchhiahna, buaina, seizures |
| A awm reng emaw, a buaithlak emaw chuan doctor hnenah hrilh rawh. | |
| Nausea, luak chhuak | Thisen sang a sang |
| Mit a inthlak a, mit a fiah lo | Cholesterol level a sang chho zel |
| Mut theih lohna emaw, mut tlem emaw | Hriatrengna hloh, thinrimna |
Take-Home Thuchah a ni
- Damdawi chu i doctor-in a tih ang chiah chiah, a hun takah leh a dose dik takah ei rawh. Pill hi tichhia emaw, tikehsawm emaw ngai suh.
- Damdawi dang zawng zawng, vitamin leh herbal product i ei zawng zawng chu i doctor hnenah hrilh rawh. A bik takin grapefruit tui in loh tur.
- He damdawi hi i ei lai leh doctor-in a rawt chhung chu naupai loh tur a ni. Hmeichhia leh mipa pawhin hei hi kan hriat chian a ngai a ni.
- Thâwk harsa, rilru na, natna nasa tak, rilru natna nasa tak i neih chuan damdawi lam thurawn zawng nghal rawh.
- He damdawi hi i tan chauh a ni. Eng thil vangin pawh midang hnenah share suh.
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