Mitochondrial Disease hi eng nge ni? A awlsam zawngin sawi ila.

A châng chuan chakna nei lo, chau reng, leh natna nei reng ang maiin i inhria em? A châng chuan, hêng chhinchhiahna inzawm lo anga langte hi kan taksa peng tê ber pakhata harsatna awm avânga lo awm thei a ni. Vawiin hian condition pakhat, a buaithlak deuh, mahse hriat a pawimawh em em kan sawi dawn a ni. Chu chu Mitochondrial Diseases a ni.

A hmasain, mitochondria chu eng nge ni?

A awlsam zawngin sawi ila, mitochondria hi kan taksa chhunga cell tin chhunga "powerhouse" te tak te te an ni. Kan in chhunga chakna pe thei tur power plant kan neih ang bawkin kan cell te hian heng mitochondria te hi hmangin an hnathawh theihna tura an mamawh chakna an siam chhuak thin. Kan ei leh in leh kan thawk oxygen hmangin heng factory te te hian kan taksa mamawh chakna 90% vel an siam chhuak thin. Chuvangin heng power plant te hi a thawk tha lo a nih chuan eng harsatna nge lo awm thei tih hi han ngaihtuah teh.

Heng power plant te hian hna an thawh that loh chuan cell te hian an mamawh energy an hmu lo. Tichuan, chutiang cell awmna taksa pengte chu a thawk tha lo ta a ni. Hei hian kan taksa peng eng pawh a nghawng thei a ni.

• Thluak
• Nervous system a ni
• Muscle te hi a ni
• Kidney a ni
• Thinlung
• Thin
• Mit
• Beng
• Pancreas a ni

Hei hian eng thil pawh a nghawng thei a ni.

Mitochondrial natna chi hrang hrangte chu engte nge ni?

He natna hi chi hrang hrang a awm a, a langsar zual thenkhat chu:

• MELAS syndrome (Mitochondrial encephalopathy, lactic acidosis leh stroke ang chi natna) 1. A rilru a hah lutuk chuan a rilru a buai em em a.
• Leber hereditary optic neuropathy (LHON) a ni a, a thih dan hi a lar hle.
• Leigh syndrome a ni
• Kearns-Sayre natna (KSS) natna hrik (KSS) .
• Myoclonic epilepsy leh ragged-red fiber natna (MERRF) te a ni.

Hei hi a buaithlak deuhin a lang thei a, mahse hengte hi symptom hrang hrang thlentu leh mitochondrial function inthlak danglamna avanga lo awm a ni tih hre reng ang che.

Heng natnate hi eng chhinchhiahna nge ni thei ang?

Hei hi natna a buaithlak ber a ni. A chhan chu mi hrang hrangah natna lan chhuah dan a inang lo thei hle a, chu chu cell natna vei chi hrang hrang leh taksa chhunga khawiah nge an awm tih a zirin a inang lo thei hle. Mi thenkhat chuan symptoms na lo tak tak an nei thei a, thenkhat erawh chuan symptoms na tak tak an nei thei thung. Chhungkaw pakhat chhungah pawh symptoms a inang lo thei.

A hnuaia table-ah hian heng natna lan chhuah dan tlangpui thenkhat tarlan a ni.

Heng symptoms te hi pian tirh atangin a intan thei a, dam chhung kum eng pawhah a lang thei bawk. Doctor chuan hei hi a ringhlel tlangpui a, chu chu a ruala symptoms a lan hian organ system inzawm lo engemaw zatah a awm a ni.

Engvangin nge hetiang natna hi a lo awm?

Hei hi a chhan ber chu genetic defects vang a ni .

A awlsam zawngin kan cell chhunga mitochondria te hian kan DNA atanga chakna siam turin an thupek an dawng thin. He DNA-ah hian inthlak danglamna emaw, mutation emaw a awm chuan mitochondria te hian instruction chu an hmu dik lo. Tichuan chakna an siam tha thei lo. Hei hian cell te a tichhe thei a, a hun hmain a thi thei bawk.

Engtin nge miin he natna hi a rochun theih?

Hengte hi genetic diseases an ni a, nu leh pa atanga fate hnena kai theih a ni tihna a ni. A chang chuan chhungkaw zingah tumahin he natna hi an nei lo a nih pawhin random genetic mutation vangin mi tu emaw chuan he natna hi a nei thei a ni.

Natna dangte hian mitochondrial function a tichhe thei em?

Awle. Secondary mitochondrial dysfunction tih a ni. Chumi awmzia chu genetic mitochondrial disease i nei lo tihna a ni a, mahse medical condition dang pakhatin i mitochondria a thawk tha lo tihna a ni. Entir nan:

• Alzheimer natna a ni
• Muscular dystrophy a awm thin
• Type 1 zunthlum vei a ni
• Multiple sclerosis (MS) natna a awm thei a ni.
• Cancer chi hrang hrang

Mitochondria hi natna hrang hrangin a nghawng thei a, chungte chu:

He natna hi engtin nge kan hriat theih ang?

He natna hi hriatchhuah a harsa deuh thei a, a chhan chu a natna lan chhuah dan a inang lo hle. Test pakhat chauh hmanga hriat theih a ni lo. I doctor chuan test hrang hrang a kalpui thei ang.

• Nang leh i chhungte damdawi lam chanchin ngun taka thlirletna .
• Taksa enfiahna kimchang tih .
• Nervous system nena inzawm test pakhat .
• Thisen leh zun test te . A chang chuan spinal tap pawh tih theih a ni.
• DNA testing neih a ni .
• A lan chhuah dan azirin MRI scan, thinlung EKG emaw Echocardiogram emaw, mit enfiahna, hriatna test, leh thluak hnathawh enfiahna tur EEG test te pawh tih theih a ni.
• A châng chuan vun emaw, taksa ruh emaw te tak te (biopsy) la a, microscope hmanga enfiah a ngai thei bawk.

Chuvang chuan heng natna chi hrang hranga specialist doctor emaw damdawi in emaw pan a, a hriat chian a pawimawh hle.

Enkawlnate chu engte nge ni?

Vanduaithlak takin mitochondrial natna hi damdawi a la awm lo. Mahse, natna lan chhuah dan enkawlna leh nunna atana hlauhawm harsatna laka invenna tur enkawlna hrang hrang a awm a ni .

• Symptoms tihziaawmna damdawi: 1.1.Entirnan, anti-epileptic damdawi.
• Vitamin leh supplement: Riboflavin, coenzyme Q10, leh carnitine ang chi te hi mi thenkhat tan chuan a tangkai thei hle.
• Ei leh in thlak danglam leh exercise: I doctor chuan i dinhmun a zirin hengte hi a rawn rawt ang.
• Taksa lam enkawlna, hnathawhna lama enkawlna emaw, thusawi hmanga enkawlna emaw.
• Hearing aid ang chi assistive devices vuah .

Mi pakhat tana tha tur chu mi dang tan chuan a thawk tha lo mai thei a, chuvangin i doctor nen inbia a, i tana tha tur enkawlna tur ruahmanna siam hi a tha ber.

He natna hi a zual zel loh nan ven theih a ni em?

He natna lo awm tur ven dan tur awm lo mahse, a natna tizualtu thil thenkhat lakah i inthiarfihlim thei a ni.

• Khaw lum lutuk emaw lum lutuk emawa awm loh tur .
• Chaw ei hi skip suh.
• Zan mut nuam tak nei rawh.
• A theih ang angin stress lakah inthiarfihlim rawh.

I doctor chuan i taksa chakna zawng zawng vawi khata hmanral ai chuan chakna humhalh turin a fuih mai thei che.

Engtikah nge Doctor ka hmuh ang?

Mitochondrial disease symptoms i neih a, nitin hnathawh i tih harsat chuan doctor pan ngei ngei tur a ni.

Seizure emaw thawk harsatna nasa tak i neih chuan damdawi in Emergency Department (ETU)-ah kal nghal tur a ni.

Nangmah emaw, i hmangaih tak emaw hian hetiang dinhmun hi i nei tih hriat chu a harsa thei hle. Mahse, i chhungte, i ṭhiante, leh doctor-te pawh tiamin medical team-te chu heng symptoms-te nêna hlawhtling taka nunpui tûrin an awm tih hre reng ang che.