I doctor-in "stem cell transplant" emaw "bone marrow transplant" emaw i mamawh thu a hrilh che chuan i hlauthawng deuh mai thei, a dik em? Chu chu thil pangngai a ni. Chûng thute hriat chu thil lian tak, buaithlâk tak leh hrehawm tak angin a lang thei a ni. Mahse, lungngai suh. Vawiin hian he thu hi a awlsam hle a, i thianpa nena inbiakna ang maiin kan sawi dawn a, chutiang chuan i rilru a zawhna awm zawng zawng chu i chhang thei ang.
A hmasain, heng stem cells te hi eng nge ni?
A awlsam zawngin sawi ila, stem cells hi kan taksaa "master cells" an ni. Kan taksa chhunga cell dang zawng zawng deuhthaw siam thei factory te an ni. A bik takin kan ruhro (bone marrow) a stem cells te hi kan thisen siamtu factory lian ber an ni. I thisena thisen sen, thisen var leh platelet te hi heng stem cell atanga siam vek a ni.
Chuvangin, he factory hian hna a thawk tha chhung chuan kan thisenah hian thil dik lo a awm lo. Mahse natna thenkhat, entirnan, cancer natna, leukemia ang chi, emaw thisen kaihhnawih natna dang avang hian he factory hi a buai thei hle. Chu chu kawng dik lo zawngin cell natna nei a siam tan tihna a ni. A châng chuan, cancer enkawlna chemotherapy dose sang tak pawhin heng stem cell hrisel tak takte hi a tichhe thei bawk.
Stem cell transplant chu he "factory" chhia emaw, chhe tawh emaw hi paih chhuakin, factory thar, hrisel tak, chu chu stem cell hrisel tak tak, taksa chhunga dah leh tihna a ni.
He transplant hi chi hnih a awm a, chungte chu:
Stem cell transplant dan tlangpui pahnih a awm a, chu chu cell lo chhuahna hmun a zirin a ni.
1. Autologous Transplant: Hei hi mahni stem cell hrisel tak tak hman a ni. Cancer natna avanga chemotherapy dose sang tak i neih dawn tih han ngaihtuah teh. Enkawlna a tan hmain i doctor chuan i taksa atanga stem cell hrisel tak tak a la khawm ang a, freezer-ah him takin a dah ang. Tichuan, chemotherapy hian cancer cells a tihlum hnuah chuan nangmah ngeiin stem cell hrisel tak tak te chu i taksaah an dah leh ang. I computer format hmaa file pawimawh tak tak backup a, format zawh hnua restore ang mai a ni.
2. Allogeneic Transplant: Hemiah hian mahni stem cells (e.g. leukemia)-ah harsatna a awm avangin mi hrisel dang (donor) atanga stem cells te chu i chhungah transplant a ni. He donor hi chhungkaw member (unaupa/unaunu), emaw, tissue type inmil nei dang tu pawh a ni thei. Hetah hian a pawimawh ber chu tissue matching a ni.Thisen pek huna thisen group matching ang bawkin hetah hian tissue chi hrang hrangte chu a buaithlak zawkin an match a ni.
| Transplant chi hrang hrang | Tu hnen atangin nge cell te hi lak chhuah? (Cell awmna hmun) . | Thil awmdan hman fo thin |
|---|---|---|
| Autologous hmanga thlak a ni | Damlo ngei a\angin (nangmah a\angin) . | Cancer thenkhat tan chuan lymphoma, multiple myeloma, leh autoimmune natna thenkhat tan. |
| Allogeneic hmanga siam chhuah a ni | A matching donor atang chuan | Leukemia, aplastic anemia, leh ruhro (bone marrow failure) natna te tan. |
Engtin nge he transplant hi tih tak tak a nih? A na em?
He zawhna hi mi tam takin an hlauh em em a ni. Dik tak chuan stem cell transplant hi surgery lian tak a ni lo. Saline solution pek che ang maiin han ngaihtuah teh. Hei pawh hi chutiang bawk chu a ni.
Heng stem cells te hi central venous catheter an tih tube bik hmangin pek i ni a, chu chu i rilru emaw, i kawr emaw chhunga thisen kalna kawng lian takah dah a ni. Heng cell te hi bag-ah dahin i taksaah an infuse a, thisen pek ang bawkin. Hetiang hian darkar engemaw zat a daih thei. Hemi chhung hian medical team ten uluk takin an lo vil reng ang che.
Cell te pek che a nih chuan natna engmah i nei lovang. Mahse, a hmaa chemotherapy treatment i pek tawh atang khan side effects (luak, luak chhuak, leh nuam lo) i nei thei a ni. Mahse i doctor chuan heng zawng zawng control nan damdawi tul tak tak a pe ang che.
A hlauhawmna leh harsatna awm thei te chu engte nge ni?
Damdawi dang ang bawkin, hlauhawmna engemaw zat a awm. Risk lian ber chu transplant hnua natna lo lang leh thei hi a ni. Mahse, chu risk chu hun kal zelah a tlahniam ta a ni.
Complication dang bik lo awm thei, a bik takin allogeneic transplant (mi dang atanga lak cell) a nih chuan an ti aGraft-versus-Host Disease (GvHD) tih a ni. A awlsam zawngin, hei hi i taksaa i dah thartu donor stem cell atanga siam immune cells te chuan nangmah ngeiin i taksa tissue te chu "ram dang" anga an hriat a, an rawn beih tan hun a ni. Bodyguard thar ten mahni chhungte an beih ang mai a ni. Hei hi thunun theihna tur enkawlna a awm.
Hei bakah hian immune system a chak loh avangin natna chi hrang hrang (bacteria, virus, fungi) a awm theihna a awm bawk.
Eng chen nge tihdam a ngaih?
Hei hi i transplant chi hrang hrang a zirin a danglam ang.
- Autologous transplant (i cells) nei tawh chu thla hnih vel chhungin a dam leh thei tlangpui.
- Allogeneic transplant (donor cells) nei tawh chu a dam kim theih nan thla engemaw zat atanga kum khat vel a ngai thei.
He damna hun hi stem cells infuse tharte chu ruhro (bone marrow)-ah an kal a, chutah chuan an awm (engraftment) a, thisen cell hrisel thar an siam tan hun a ni. Allogeneic transplant hnu ni 100 hmasa ber hi a pawimawh hle. Hemi hun chhung hian damdawi in hnaih taka awm turin Doctor-te chuan an fuih thei che a ni.
Recovery chhunga i tana i tih theih tur thil
Hei hi zinkawng thui tak a nih avangin he hun chhung hian i in enkawl tha a pawimawh hle.
- I vun hi naute vun angin enkawl rawh: I vun hi enkawl hnuah a sensitive hle mai thei. Sahbawn leh shampoo nalh tak tak hmang thin ang che. I vun chu a hnim reng la, ni chhuahna hmuna i chhuah dawnin inveng rawh.
- Ei leh in tha tak ei: Hei hi a pawimawh hle. Sa, sangha, thlai, thei leh buhfai tui tak ei rawh. Hemi hun chhung hian salad raw, thei silfai loh, artui raw, leh bawnghnute pasteurized loh ei loh tur a ni a, a chhan chu natna hrik a thlen tam zawk vang a ni.
- Infection laka invenna: Kut sil fo thin ang che. Mipui tamna hmun leh mi damlohna hmunte chu pumpelh tur a ni. I doctor hnenah eng vaccine nge i lak tur tih zawt rawh.
- I ha enkawl dan: Thla 6 danah ha enkawltu pan thin ang che. Oral hygiene tha tak vawng reng ang che.
- Chawlh tam rawh: Ni engemaw zat chu i chau hle ang. Ni dangah chuan ropui takin i inhria ang. Ni hahthlak tak hman hi lungngai suh, i taksain chawlh hahdam a mamawh tih chhinchhiahna mai a ni.
- I rilru hriselna ngaihtuah rawh: Hetih hun chhung hian emotional ups and downs i neih hi thil pangngai a ni. I lungngaih chuan i doctor, i chhungte nen inbia la, a tul chuan counselor hnenah tanpuina zawng rawh.
Heng symptoms te hi i neih chuan doctor ko nghal tur a ni.
I dam chhungin a hnuaia symptoms te hi i neih chuan i medical team hnenah hriattir nghal rawh.
| Symptom a ni | Eng nge ngaihven tur |
|---|---|
| Khawsik leh khawsik | Taksa lumna 38 Celsius (100.4 Fahrenheit) aia sang, khawsik, khuh, leh khuh chhuak. |
| Thâwk harsa | Thâwk harsa emaw, rilru na emaw. |
| Vun a inthlak danglam thin | Pimples, eczema, emaw rashes lo lang thar. |
| Zun chhuah dan a inthlak danglam thin | Zun tam emaw, zun laiin kang emaw, na emaw. |
| Thildang | Dizziness , luak chhuak, ril\am, emaw, thil dang danglam tak emaw a awm thei. |
Cancer emaw, thisen lama harsatna emaw dotu tan chuan stem cell transplant hi nun tidanglam thei thil a ni thei. Mahse, zinkawng awlsam a ni lo. Taksa leh rilru chakna tam tak a mamawh a ni. He damdawi hi i ngaihtuah a nih chuan i doctor nen inhawng takin sawiho la, a thatna leh tha lo chu hrethiam rawh. I dinhmun a zirin thurawn tha ber ber an pe ang che.
Take-Home Thuchah a ni
- Stem cell transplant hi nunna chhanhim thei damdawi a ni a, natna khirh tak tak a tidam thei a, a thunun thei bawk. Surgery lian tak a ni lo va, saline solution pek ang chi procedure a ni.
- Hei hi zinkawng thui tak a ni. Dam nan hun a duh a ni. Hetih hun chhung hian i in enkawl that a pawimawh hle. A bik takin faina leh ei leh in lam ngaih pawimawh.
- Inenkawl hnua natna lan chhuah dan danglam (khawsik, khuh, ril na) i neih chuan ngaihthah suh la, doctor hnenah hriattir nghal rawh.
- I hlauhthawnna, rinhlelhna leh zawhna zawng zawngte chu i medical team-te nen zalen takin sawiho rawh. I tanpui turin an awm reng a ni. He zinkawngah hian nangmah chauh i ni lo.
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