VUMERITY (Diroximel Fumarate)ꯒꯤ ꯃꯔꯃꯗꯥ ꯈꯉꯂꯁꯤ? ꯑꯦꯝ.ꯑꯦꯁ.ꯀꯤꯗꯃꯛꯇꯥ ꯗ꯭ꯔꯒ ꯑꯁꯤꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯅꯍꯥꯛꯅꯥ ꯈꯪꯖꯤꯅꯒꯗꯕꯥ ꯋꯥꯐꯃꯁꯤꯡ꯫

ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯅꯥ ꯅꯍꯥꯀꯄꯨ ꯅꯠꯠꯔꯒꯥ ꯅꯍꯥꯛꯀꯥ ꯅꯛꯅꯕꯥ ꯃꯤꯑꯣꯏ ꯑꯃꯕꯨ ‘ꯃꯜꯇꯤꯄꯜ ꯁ꯭ꯛꯂꯦꯔꯣꯁꯤꯁ’ (MS) ꯀꯧꯕꯥ ꯀꯟꯗꯤꯁꯟ ꯑꯃꯥ ꯂꯩꯔꯦ ꯍꯥꯌꯅꯥ ꯈꯪꯂꯕ꯭ꯔꯥ? ꯀꯔꯤꯒꯨꯝꯕꯥ ꯑꯣꯏꯔꯒꯗꯤ, ꯑꯗꯣꯃꯗꯥ ꯂꯥꯏꯌꯦꯡ ꯑꯃꯥ ꯑꯣꯏꯅꯥ ‘ꯗꯥꯏꯔꯣꯛꯁꯤꯃꯦꯜ ꯐꯨꯃꯔꯦꯠ’ ꯀꯧꯕꯥ ꯗ꯭ꯔꯒ ꯑꯃꯥ ꯄꯤꯈꯤꯕꯥ ꯑꯣꯏꯔꯝꯕꯥ ꯌꯥꯏ, ꯃꯁꯤ ꯕ꯭ꯔꯥꯟꯗ ꯅꯦꯝ VUMERITYꯒꯤ ꯃꯈꯥꯗꯥ ꯂꯥꯀꯏ꯫ ꯃꯃꯤꯡ ꯑꯁꯤ ꯈꯔꯥ ꯍꯦꯟꯅꯥ ꯂꯨꯝꯅꯥ ꯂꯧꯕꯥ ꯌꯥꯏ꯫ ꯑꯗꯨꯕꯨ ꯋꯥꯈꯜ ꯋꯥꯕꯥ ꯂꯩꯔꯣꯏꯗꯕꯅꯤ꯫ ꯑꯥꯔꯇꯤꯀꯜ ꯑꯁꯤꯗꯥ ꯑꯩꯈꯣꯌꯅꯥ ꯗ꯭ꯔꯒ ꯑꯁꯤꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯌꯥꯝꯅꯥ ꯂꯥꯏꯅꯥ ꯋꯥꯔꯤ ꯁꯥꯒꯅꯤ, ꯅꯍꯥꯛꯅꯥ ꯃꯔꯨꯞ ꯑꯃꯗꯥ ꯍꯥꯌꯔꯀꯄꯒꯨꯝꯅꯥ, ꯃꯁꯤꯅꯥ ꯀꯔꯝꯅꯥ ꯊꯕꯛ ꯇꯧꯕꯒꯦ, ꯃꯁꯤ ꯁꯤꯖꯤꯟꯅꯔꯤꯉꯩꯗꯥ ꯀꯔꯤꯒꯤꯗꯃꯛꯇꯥ ꯆꯦꯀꯁꯤꯅꯒꯗꯒꯦ, ꯑꯃꯁꯨꯡ ꯃꯁꯤꯒꯤ ꯁꯥꯏꯗ ꯏꯐꯦꯛꯇꯁꯤꯡ꯫

ꯑꯍꯥꯅꯕꯗꯥ ꯃꯁꯤ ꯀꯔꯝꯕꯥ ꯃꯈꯂꯒꯤ ꯍꯤꯗꯥꯛ ꯑꯣꯏꯕꯒꯦ ꯍꯥꯌꯕꯗꯨ ꯌꯦꯡꯁꯤ꯫

ꯌꯥꯝꯅꯥ ꯂꯥꯏꯅꯥ ꯍꯥꯌꯔꯕꯗꯥ, ‘ꯃꯜꯇꯤꯄꯜ ꯁ꯭ꯛꯂꯦꯔꯣꯁꯤꯁ’ (MS) ꯍꯥꯌꯕꯁꯤ ꯑꯩꯈꯣꯌꯒꯤ ꯍꯀꯆꯥꯡꯒꯤ ꯏꯁꯥꯒꯤ ꯏꯝꯝꯌꯨꯟ ꯁꯤꯁ꯭ꯇꯦꯝ ꯑꯁꯤ ꯑꯣꯚꯔꯑꯦꯛꯇꯤꯚ ꯑꯣꯏꯔꯀꯄꯥ ꯑꯃꯁꯨꯡ ꯑꯩꯈꯣꯌꯒꯤ ꯏꯁꯥꯒꯤ ꯅꯔꯚ ꯁꯤꯁ꯭ꯇꯦꯃꯗꯥ ꯑꯦꯇꯦꯛ ꯇꯧꯕꯥ ꯀꯟꯗꯤꯁꯟ ꯑꯃꯅꯤ꯫ ꯃꯁꯤ ꯑꯩꯈꯣꯌꯒꯤ ꯏꯁꯥꯒꯤ ꯗꯤꯐꯦꯟꯁꯁꯤꯡꯅꯥ ꯑꯩꯈꯣꯌꯕꯨ ꯌꯦꯛꯅꯕꯥ ꯑꯣꯏꯅꯥ ꯂꯧꯗꯨꯅꯥ ꯑꯩꯈꯣꯌꯗꯥ ꯑꯦꯇꯦꯛ ꯇꯧꯕꯒꯨꯝꯕꯅꯤ꯫

ꯍꯧꯖꯤꯛ ꯗꯤꯔꯣꯛꯁꯤꯃꯦꯜ ꯐꯨꯃꯔꯦꯠ ꯀꯧꯕꯥ ꯍꯤꯗꯥꯛ ꯑꯁꯤꯅꯥ ꯑꯣꯚꯔꯑꯦꯛꯇꯤꯕ ꯏꯝꯝꯌꯨꯟ ꯁꯤꯁ꯭ꯇꯦꯝ ꯑꯁꯤ ꯂꯦꯡꯗꯅꯥ ꯂꯩꯍꯟꯗꯨꯅꯥ ꯊꯕꯛ ꯇꯧꯔꯤ꯫ ꯃꯁꯤꯅꯥ ꯅꯔꯚ ꯁꯤꯁ꯭ꯇꯦꯃꯗꯥ ꯊꯣꯀꯄꯥ ꯑꯃꯥꯡ-ꯑꯇꯥ ꯍꯟꯊꯍꯜꯂꯤ꯫ ꯃꯁꯤꯅꯥ ꯂꯥꯏꯑꯣꯡꯁꯤꯡ ꯍꯦꯟꯅꯥ ꯐꯒꯠꯂꯀꯄꯥ ꯀꯟꯠꯔꯣꯜ ꯇꯧꯕꯗꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯏ ꯑꯃꯁꯨꯡ ꯂꯥꯌꯅꯥ ꯑꯁꯤꯅꯥ ꯊꯣꯀꯍꯅꯕꯥ ꯐ꯭ꯂꯦꯌꯔ-ꯑꯄꯁꯤꯡꯒꯤ ꯆꯥꯡ ꯍꯟꯊꯍꯜꯂꯤ꯫

ꯍꯤꯗꯥꯛ-ꯂꯥꯡꯊꯛ ꯍꯧꯗ꯭ꯔꯤꯉꯩꯗꯥ ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯗꯥ ꯈꯪꯍꯅꯒꯗꯕꯥ ꯋꯥꯐꯃꯁꯤꯡ꯫

ꯍꯤꯗꯥꯛ ꯑꯁꯤ ꯄꯤꯗ꯭ꯔꯤꯉꯩꯗꯥ ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯅꯥ ꯅꯍꯥꯛꯀꯤ ꯃꯄꯨꯡꯐꯥꯕꯥ ꯍꯦꯂꯊ ꯍꯤꯁ꯭ꯇꯔꯤ ꯑꯗꯨ ꯈꯪꯖꯤꯅꯕꯥ ꯍꯥꯌꯕꯁꯤ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ꯫ ꯃꯔꯝ ꯑꯗꯨꯅꯥ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯃꯈꯥꯗꯥ ꯄꯤꯔꯤꯕꯥ ꯀꯟꯗꯤꯁꯅꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯃꯅꯨꯡꯗꯥ ꯑꯃꯍꯦꯛꯇꯥ ꯂꯩꯔꯕꯗꯤ, ꯍꯤꯗꯥꯛ ꯑꯁꯤ ꯍꯧꯗ꯭ꯔꯤꯉꯩꯗꯥ ꯃꯈꯣꯌꯗꯥ ꯁꯣꯌꯗꯅꯥ ꯈꯪꯍꯅꯕꯤꯌꯨ꯫

• ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯍꯧꯖꯤꯛꯀꯤ ꯑꯣꯏꯅꯥ ꯏꯅꯐꯦꯛꯁꯟ ꯂꯩꯕꯥ ꯀꯟꯗꯤꯁꯟ ꯑꯃꯍꯦꯛꯇ (ꯈꯨꯗꯝ ꯑꯣꯏꯅꯥ, ꯂꯥꯏꯍꯧ, ꯀꯣꯛ ꯆꯤꯀꯄꯥ) ꯂꯩꯔꯕꯗꯤ꯫
• ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯀꯤꯗꯅꯤꯒꯤ ꯂꯥꯌꯅꯥ ꯂꯩꯔꯕꯗꯤ .
• ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯂꯤꯚꯔꯒꯤ ꯂꯥꯌꯅꯥ ꯂꯩꯔꯕꯗꯤ .
• ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯃꯃꯥꯡꯗꯥ ꯋꯥꯏꯇꯦꯞ ꯕ꯭ꯂꯗ ꯁꯦꯜ ꯀꯥꯎꯟꯇ ꯅꯦꯝꯅꯥ ꯂꯩꯔꯕꯗꯤ .
• ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯗꯤꯔꯣꯛꯁꯤꯃꯦꯜ ꯐꯨꯃꯔꯦꯠ, ꯗꯥꯏꯃꯦꯊꯤꯜ ꯐꯨꯃꯔꯦꯠ ꯅꯠꯠꯔꯒꯥ ꯑꯇꯩ ꯍꯤꯗꯥꯛ-ꯂꯥꯡꯊꯛ, ꯆꯤꯟꯖꯥꯛ ꯅꯠꯠꯔꯒꯥ ꯗꯥꯏꯑꯦꯇꯔꯤ ꯑꯃꯍꯦꯛꯇꯒꯤ ꯑꯦꯂꯥꯔꯖꯤꯒꯤ ꯔꯤꯑꯦꯛꯁꯟ ꯂꯩꯔꯕꯗꯤ꯫
• ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯃꯤꯔꯣꯜꯂꯤꯕꯤ ꯅꯠꯠꯔꯒꯥ ꯑꯉꯥꯡ ꯑꯃꯥ ꯄꯣꯛꯂꯕꯗꯤ .
• ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯈꯣꯝꯂꯥꯡ ꯄꯤꯊꯀꯄꯥ ꯃꯃꯥ ꯑꯃꯥ ꯑꯣꯏꯔꯕꯗꯤ .

ꯑꯩꯅꯥ ꯍꯤꯗꯥꯛ ꯑꯁꯤ ꯃꯇꯧ ꯀꯔꯝꯅꯥ ꯇꯁꯦꯡꯅꯥ ꯁꯤꯖꯤꯟꯅꯒꯗꯒꯦ?

ꯍꯤꯗꯥꯛ-ꯂꯥꯡꯊꯛ ꯑꯃꯗꯒꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯍꯦꯟꯅꯥ ꯀꯥꯟꯅꯕꯥ ꯐꯪꯅꯕꯒꯤꯗꯃꯛ, ꯃꯗꯨ ꯌꯥꯊꯪ ꯄꯤꯔꯀꯄꯒꯤ ꯃꯇꯨꯡꯏꯟꯅꯥ ꯁꯤꯖꯤꯟꯅꯕꯥ ꯍꯥꯌꯕꯁꯤ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ꯫

• ꯃꯁꯤꯒꯤ ꯍꯤꯗꯥꯛ ꯑꯁꯤ ꯀꯦꯄꯁꯨꯂꯗꯥ ꯂꯥꯀꯏ꯫ ꯃꯁꯤ ꯏꯁꯤꯡꯒꯤ ꯒ꯭ꯂꯥꯁ ꯑꯃꯅꯥ ꯊꯀꯎ꯫
• ꯀꯦꯄꯁꯨꯂꯁꯤꯡ ꯑꯁꯤ ꯀꯩꯗꯧꯉꯩꯗꯥ ꯊꯨꯒꯥꯌꯒꯅꯨ, ꯁꯣꯀꯍꯜꯂꯣꯏꯗꯕꯅꯤ ꯅꯠꯠꯔꯒꯥ ꯆꯥꯀꯍꯜꯂꯣꯏꯗꯕꯅꯤ꯫ ꯃꯈꯣꯌ ꯃꯄꯨꯡꯐꯥꯅꯥ ꯂꯧꯁꯤꯅꯒꯗꯕꯅꯤ꯫
• ꯅꯍꯥꯛꯀꯤ ꯍꯤꯗꯥꯛ ꯑꯗꯨ ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯅꯥ ꯇꯥꯀꯄꯥ ꯃꯇꯨꯡꯏꯟꯅꯥ, ꯑꯆꯨꯝꯕꯥ ꯃꯇꯃꯗꯥ ꯂꯧ꯫
• ꯃꯁꯤ ꯆꯥꯅꯕꯥ ꯆꯤꯟꯖꯥꯛꯀꯥ ꯂꯣꯌꯅꯅꯥ ꯅꯠꯠꯔꯒꯥ ꯆꯥꯗꯅꯥ ꯂꯧꯕꯥ ꯌꯥꯏ꯫ ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ, ꯃꯤꯑꯣꯏ ꯈꯔꯗꯗꯤ ꯆꯥꯅꯕꯥ ꯆꯤꯟꯖꯥꯛ ꯌꯥꯎꯗꯅꯥ ꯂꯧꯔꯕꯗꯤ ꯃꯌꯥꯏ ꯑꯣꯏꯕꯥ ꯁ꯭ꯇꯣꯃꯥꯛ ꯑꯄꯁꯦꯠ ꯂꯩꯔꯀꯄꯥ ꯌꯥꯏ꯫ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯃꯁꯤ ꯊꯣꯛꯂꯕꯗꯤ, ꯃꯗꯨ ꯑꯄꯤꯀꯄꯥ ꯆꯥꯀꯁꯉ ꯑꯃꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯂꯧꯒꯗꯕꯅꯤ꯫
• ꯑꯗꯨꯕꯨ ꯃꯐꯃꯁꯤꯗꯥ ꯋꯥꯈꯂꯗꯥ ꯊꯃꯒꯗꯕꯥ ꯋꯥꯐꯝ ꯑꯃꯥ ꯂꯩ: ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯍꯤꯗꯥꯛ ꯑꯗꯨ ꯆꯥꯅꯕꯥ ꯆꯤꯟꯖꯥꯛ ꯑꯃꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯂꯧꯔꯕꯗꯤ, ꯃꯁꯤ ꯀꯦꯂꯣꯔꯤ ꯌꯥꯝꯅꯥ ꯌꯥꯎꯕꯥ ꯅꯠꯠꯔꯒꯥ ꯐꯦꯠ ꯌꯥꯝꯅꯥ ꯌꯥꯎꯕꯥ ꯆꯥꯅꯕꯥ ꯑꯣꯏꯔꯣꯏꯗꯕꯅꯤ꯫ ꯌꯥꯝꯅꯥ ꯂꯥꯏꯅꯥ ꯍꯥꯌꯔꯕꯗꯥ, ꯃꯁꯤꯗꯥ ꯀꯦꯂꯣꯔꯤ 700ꯗꯒꯤ ꯍꯦꯟꯅꯥ ꯑꯃꯁꯨꯡ ꯐꯦꯠ ꯒ꯭ꯔꯥꯝ 30ꯗꯒꯤ ꯍꯦꯟꯅꯥ ꯌꯥꯎꯔꯣꯏꯗꯕꯅꯤ꯫ (ꯈꯨꯗꯝ ꯑꯣꯏꯅꯥ, ꯃꯁꯤ ꯐ꯭ꯔꯥꯏꯗ ꯔꯥꯏꯁ ꯅꯠꯠꯔꯒꯥ ꯀꯣꯠꯇꯨꯒꯨꯝꯕꯥ ꯑꯀꯅꯕꯥ ꯆꯥꯀꯁꯉ ꯑꯃꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯂꯧꯔꯣꯏꯗꯕꯅꯤ, ꯃꯈꯣꯌ ꯑꯁꯤ ꯇꯦꯜ ꯌꯥꯝꯅꯥ ꯌꯥꯎꯅꯥ ꯁꯦꯝꯕꯅꯤ꯫)
• ꯍꯤꯗꯥꯛ ꯑꯁꯤ ꯌꯨꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯃꯄꯨꯡꯐꯥꯅꯥ ꯊꯀꯄꯤꯒꯅꯨ꯫
• ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯅꯥ ꯅꯍꯥꯀꯄꯨ ꯊꯤꯡꯅꯕꯥ ꯍꯥꯌꯔꯀꯄꯥ ꯐꯥꯎꯕꯗꯥ ꯍꯤꯗꯥꯛ ꯑꯁꯤ ꯃꯈꯥ ꯇꯥꯅꯥ ꯁꯤꯖꯤꯟꯅꯧ꯫

ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯍꯤꯗꯥꯛ-ꯂꯥꯡꯊꯛꯀꯤ ꯗꯣꯖ ꯑꯃꯥ ꯁꯣꯟꯊꯔꯕꯗꯤ ꯀꯔꯤ ꯇꯧꯒꯗꯒꯦ?

ꯀꯔꯤꯒꯨꯝꯕꯥ ꯃꯇꯃꯗꯥ ꯑꯩꯈꯣꯌꯅꯥ ꯑꯩꯈꯣꯌꯒꯤ ꯍꯤꯗꯥꯛ ꯂꯥꯡꯊꯛ ꯂꯧꯕꯥ ꯀꯥꯑꯣꯊꯣꯀꯏ꯫ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯃꯗꯨ ꯑꯣꯏꯔꯕꯗꯤ, ꯅꯍꯥꯛꯅꯥ ꯅꯤꯡꯁꯤꯡꯂꯀꯄꯥ ꯃꯇꯃꯗꯥ ꯌꯥꯝꯅꯥ ꯊꯨꯅꯥ ꯃꯤꯁ ꯗꯣꯖ ꯑꯗꯨ ꯂꯧ꯫ ꯑꯗꯨꯕꯨ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯃꯊꯪꯒꯤ ꯗꯣꯖꯒꯤ ꯃꯇꯝ ꯌꯧꯔꯛꯂꯕꯗꯤ, ꯃꯥꯡꯈꯤꯕꯥ ꯗꯣꯖ ꯑꯗꯨ ꯊꯥꯗꯣꯛꯇꯨꯅꯥ ꯃꯊꯪꯒꯤ ꯗꯣꯖ ꯑꯗꯨ ꯂꯦꯄꯊꯣꯛꯂꯕꯥ ꯃꯇꯃꯗꯥ ꯂꯧ꯫ ꯀꯩꯗꯧꯉꯩꯗꯥ ꯗꯕꯜ ꯗꯣꯖ ꯑꯃꯥ ꯂꯧꯔꯣꯏꯗꯕꯅꯤ꯫

ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯍꯤꯗꯥꯛ-ꯂꯥꯡꯊꯛ ꯌꯥꯝꯅꯥ ꯂꯧꯔꯕꯗꯤ ꯀꯔꯤ ꯇꯧꯒꯗꯒꯦ?

ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯑꯀꯛꯅꯕꯥ ꯗꯣꯖ ꯑꯗꯨꯗꯒꯤ ꯍꯦꯟꯅꯥ ꯂꯧꯈꯤꯕꯥ ꯑꯣꯏꯔꯕꯗꯤ, ꯈꯨꯗꯛꯇꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯅꯀꯄꯥ ꯍꯣꯁ꯭ꯄꯤꯇꯥꯜ ꯏꯃꯔꯖꯦꯟꯁꯤ ꯗꯤꯄꯥꯔꯇꯃꯦꯟꯇ (ETU)ꯗꯥ ꯆꯠꯂꯨ . ꯅꯠꯠꯔꯒꯥ, ꯄꯥꯎꯇꯥꯛ ꯂꯧꯅꯕꯒꯤꯗꯃꯛ ꯀꯣꯂꯝꯕꯣ ꯅꯦꯁꯅꯦꯜ ꯍꯣꯁ꯭ꯄꯤꯇꯥꯂꯗꯥ ꯂꯩꯕꯥ ꯅꯦꯁꯅꯦꯜ ꯄꯣꯏꯖꯅꯁ ꯏꯅꯐꯣꯔꯃꯦꯁꯟ ꯁꯦꯟꯇꯔꯗꯥ ꯐꯣꯟ ꯇꯧꯕꯤꯌꯨ꯫

ꯍꯤꯗꯥꯛ-ꯂꯥꯡꯊꯛ ꯂꯧꯕꯥ ꯃꯇꯃꯗꯥ ꯅꯍꯥꯛꯅꯥ ꯃꯔꯨꯑꯣꯏꯅꯥ ꯆꯦꯀꯁꯤꯅꯒꯗꯕꯥ ꯋꯥꯐꯃꯁꯤꯡ꯫

ꯍꯤꯗꯥꯛ ꯑꯁꯤ ꯁꯤꯖꯤꯟꯅꯔꯤꯉꯩꯗꯥ ꯅꯍꯥꯛꯀꯤ ꯍꯀꯆꯥꯡꯗꯥ ꯑꯍꯣꯡꯕꯥ ꯂꯥꯀꯄꯗꯥ ꯄꯨꯛꯅꯤꯡ ꯆꯪꯕꯥ ꯍꯥꯌꯕꯁꯤ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ꯫

• ꯆꯥꯡ ꯅꯥꯏꯅꯥ ꯃꯦꯗꯤꯀꯦꯜ ꯆꯦꯛ-ꯑꯞ ꯇꯧꯕꯥ: ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯅꯥ ꯅꯍꯥꯀꯄꯨ ꯀꯗꯥꯏꯗꯥ ꯑꯃꯨꯛ ꯍꯟꯅꯥ ꯂꯥꯀꯄꯥ ꯃꯊꯧ ꯇꯥꯕꯒꯦ ꯍꯥꯌꯕꯗꯨ ꯈꯪꯍꯜꯂꯛꯀꯅꯤ꯫ ꯅꯍꯥꯛꯀꯤ ꯀꯟꯗꯤꯁꯟ ꯑꯗꯨ ꯌꯦꯡꯁꯤꯟꯅꯕꯥ ꯅꯨꯃꯤꯠꯁꯤꯡ ꯑꯗꯨꯗꯥ ꯁꯣꯌꯗꯅꯥ ꯆꯠꯂꯨ꯫ ꯃꯍꯥꯛꯅꯥ ꯍꯤꯗꯥꯛ ꯑꯁꯤ ꯂꯧꯔꯤꯉꯩꯗꯥ ꯅꯍꯥꯛꯀꯤ ꯏꯗꯥ ꯂꯩꯔꯤꯕꯥ ꯋꯥꯏꯇꯦꯞ ꯁꯦꯂꯁꯤꯡꯒꯤ ꯃꯁꯤꯡ ꯑꯁꯤꯅꯆꯤꯡꯕꯥ ꯄꯣꯠꯁꯀꯁꯤꯡ ꯌꯦꯡꯁꯤꯟꯅꯕꯥ ꯕ꯭ꯂꯗ ꯇꯦꯁ꯭ꯠ ꯇꯧꯕꯁꯨ ꯌꯥꯊꯪ ꯄꯤꯒꯅꯤ꯫
• ꯐ꯭ꯂꯁ (flushing): ꯃꯤꯑꯣꯏ ꯈꯔꯗꯗꯤ ꯍꯤꯗꯥꯛ ꯑꯁꯤ ꯂꯧꯔꯕꯥ ꯃꯇꯨꯡꯗꯥ ꯃꯈꯣꯌꯒꯤ ꯃꯃꯥꯌ, ꯈꯣꯡ ꯅꯠꯠꯔꯒꯥ ꯈꯣꯡꯗꯥ ꯐ꯭ꯂꯁ ꯇꯧꯕꯥ, ꯑꯁꯥꯕꯥ ꯅꯠꯠꯔꯒꯥ ꯃꯩꯅꯥ ꯆꯥꯀꯄꯥ ꯌꯥꯏ꯫ ꯃꯁꯤꯕꯨ ꯐ꯭ꯂꯁ (flushing) ꯍꯥꯌꯅꯥ ꯀꯧꯏ꯫ ꯃꯁꯤ ꯃꯍꯧꯁꯥꯅꯥ ꯈꯨꯗꯣꯡꯊꯤꯅꯤꯉꯥꯏ ꯑꯣꯏꯗꯦ ꯑꯃꯁꯨꯡ ꯃꯇꯝ ꯈꯔꯒꯤ ꯃꯇꯨꯡꯗꯥ ꯂꯥꯛꯀꯅꯤ꯫ ꯃꯁꯤ ꯍꯟꯊꯍꯟꯅꯕꯥ, ꯑꯩꯈꯣꯌꯅꯥ ꯃꯃꯥꯡꯗꯥ ꯍꯥꯌꯈꯤꯕꯒꯨꯝꯅꯥ, ꯍꯤꯗꯥꯛ ꯑꯁꯤ ꯐꯦꯠ ꯅꯦꯝꯕꯥ/ ꯀꯦꯂꯣꯔꯤ ꯅꯦꯝꯕꯥ ꯆꯤꯟꯖꯥꯛ ꯑꯃꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯂꯧꯕꯅꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯒꯅꯤ꯫ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯃꯇꯃꯗꯥ, ꯑꯦꯁ꯭ꯄꯤꯔꯤꯟ ꯑꯃꯥ ꯂꯧꯕꯅꯥ ꯃꯁꯤ ꯍꯟꯊꯍꯅꯕꯗꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯒꯅꯤ꯫ ꯑꯗꯨꯕꯨ ꯃꯁꯤ ꯑꯍꯥꯅꯕꯗꯥ ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯒꯥ ꯇꯥꯟꯅꯗꯅꯥ ꯇꯧꯔꯣꯏꯗꯕꯅꯤ꯫
• ꯏꯅꯐꯦꯛꯁꯅꯒꯤ ꯔꯤꯁ꯭ꯛ: ꯍꯤꯗꯥꯛ ꯑꯁꯤꯅꯥ ꯏꯝꯝꯌꯨꯟ ꯁꯤꯁ꯭ꯇꯦꯝ ꯁꯣꯀꯍꯅꯕꯅꯥ ꯃꯔꯝ ꯑꯣꯏꯗꯨꯅꯥ ꯅꯍꯥꯛꯅꯥ ꯏꯅꯐꯦꯛꯁꯟ ꯂꯥꯀꯄꯒꯤ ꯔꯤꯁ꯭ꯛ ꯈꯔꯥ ꯍꯦꯅꯒꯠꯂꯀꯄꯥ ꯌꯥꯏ꯫ ꯃꯔꯝ ꯑꯗꯨꯅꯥ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯂꯥꯏꯑꯣꯡꯁꯤꯡ ꯍꯥꯌꯕꯗꯤ ꯂꯥꯏꯑꯣꯡꯁꯤꯡ, ꯆꯤꯀꯄꯥ, ꯀꯣꯛ ꯆꯤꯀꯄꯥ, ꯅꯠꯠꯔꯒꯥ ꯀꯣꯛ ꯆꯤꯀꯄꯥ ꯑꯁꯤꯅꯆꯤꯡꯕꯥ ꯂꯥꯏꯑꯣꯡꯁꯤꯡ ꯂꯩꯔꯕꯗꯤ ꯃꯁꯥ ꯃꯊꯟꯇꯥ ꯍꯤꯗꯥꯛ ꯂꯥꯡꯊꯛ ꯄꯤꯖꯒꯅꯨ ꯑꯃꯁꯨꯡ ꯗꯣꯛꯇꯔ ꯑꯃꯒꯥ ꯇꯥꯟꯅꯒꯅꯨ꯫ ꯑꯅꯥꯕꯥ ꯃꯤꯑꯣꯏꯁꯤꯡꯅꯥ ꯂꯦꯡ-ꯑꯣꯠꯄꯒꯤ ꯃꯐꯃꯁꯤꯡꯗꯒꯤ ꯂꯥꯞꯅꯥ ꯂꯩꯅꯕꯥ ꯍꯣꯠꯅꯒꯗꯕꯅꯤ꯫
• ꯌꯥꯝꯅꯥ ꯊꯨꯅꯥ ꯊꯣꯀꯄꯥ ꯑꯗꯨꯕꯨ ꯌꯥꯝꯅꯥ ꯁꯥꯊꯤꯕꯥ ꯕ꯭ꯔꯦꯟ ꯏꯅꯐꯦꯛꯁꯟ ꯑꯃꯥ:ꯃꯁꯤ ꯌꯥꯝꯅꯥ ꯇꯣꯏꯅꯥ ꯊꯣꯀꯏ꯫ ꯑꯗꯨꯕꯨ ꯆꯦꯀꯁꯤꯟꯅꯥ ꯂꯩꯕꯥ ꯑꯁꯤ ꯌꯥꯝꯅꯥ ꯃꯔꯨ ꯑꯣꯏ꯫ ꯍꯤꯗꯥꯛ ꯑꯁꯤꯅꯥ ꯑꯅꯥꯕꯥ ꯈꯔꯗꯥ ꯑꯀꯅꯕꯥ ꯕ꯭ꯔꯦꯟ ꯏꯅꯐꯦꯛꯁꯟ (PML - Progressive Multifocal Leukoencephalopathy) ꯊꯣꯀꯍꯅꯕꯥ ꯌꯥꯏ꯫ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯃꯤꯠ ꯎꯗꯕꯒꯤ ꯁꯃꯁ꯭ꯌꯥ ꯂꯩꯔꯕꯗꯤ, ꯋꯥꯈꯜ ꯈꯅꯕꯥ ꯉꯃꯗꯕꯥ, ꯋꯥ ꯉꯥꯡꯕꯗꯥ ꯑꯋꯥꯕꯥ ꯂꯩꯔꯕꯗꯤ, ꯅꯠꯠꯔꯒꯥ ꯈꯣꯡꯅꯥ ꯆꯠꯄꯥ ꯅꯠꯠꯔꯒꯥ ꯅꯍꯥꯛꯀꯤ ꯕꯦꯂꯦꯟꯁ ꯊꯝꯕꯗꯥ ꯑꯋꯥꯕꯥ ꯂꯩꯔꯕꯗꯤ , ꯈꯨꯗꯛꯇꯥ ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯗꯥ ꯍꯥꯌꯌꯨ꯫

ꯍꯤꯗꯥꯛ ꯁꯤꯖꯤꯟꯅꯔꯤꯉꯩꯗꯥ ꯊꯣꯀꯄꯥ ꯌꯥꯕꯥ ꯁꯥꯏꯗ ꯏꯐꯦꯛꯇꯁꯤꯡ꯫

ꯍꯤꯗꯥꯛ ꯑꯃꯍꯦꯛꯇꯒꯨꯝꯅꯥ ꯃꯁꯤꯒꯤ ꯑꯃꯅꯥ ꯁꯥꯏꯗ ꯏꯐꯦꯛꯇ ꯈꯔꯥ ꯂꯩꯕꯥ ꯌꯥꯏ꯫ ꯈꯔꯗꯤ ꯌꯥꯝꯅꯥ ꯁꯥꯊꯤꯅꯥ ꯁꯣꯀꯍꯜꯂꯤ, ꯃꯔꯝ ꯑꯗꯨꯅꯥ ꯅꯍꯥꯛꯅꯥ ꯈꯨꯗꯛꯇꯥ ꯃꯦꯗꯤꯀꯦꯂꯒꯤ ꯄꯥꯎꯇꯥꯛ ꯂꯧꯒꯗꯕꯅꯤ꯫ ꯈꯔꯗꯤ ꯑꯁꯨꯛ ꯌꯥꯝꯅꯥ ꯁꯥꯊꯤꯕꯥ ꯑꯣꯏꯗꯦ, ꯑꯗꯨꯕꯨ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯃꯈꯣꯌꯅꯥ ꯂꯦꯞꯄꯥ ꯂꯩꯇꯅꯥ ꯍꯣꯠꯅꯔꯕꯗꯤ ꯅꯍꯥꯛꯅꯥ ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯗꯥ ꯈꯪꯍꯅꯒꯗꯕꯅꯤ꯫ ꯍꯥꯌꯔꯤꯕꯁꯤꯡ ꯑꯁꯤ ꯇꯣꯉꯥꯟꯅꯥ ꯌꯦꯡꯁꯤ꯫

ꯅꯍꯥꯛꯀꯤ ꯍꯤꯗꯥꯛ ꯑꯗꯨ ꯀꯔꯝꯅꯥ ꯁꯥꯐꯅꯥ ꯊꯃꯒꯗꯒꯦ?

• ꯑꯉꯥꯡꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯄꯣꯠꯆꯩꯁꯤꯡꯅꯥ ꯌꯧꯕꯥ ꯉꯃꯗꯕꯥ ꯃꯐꯃꯗꯥ ꯊꯝꯃꯨ .
• ꯔꯨꯝ ꯇꯦꯝꯄꯦꯔꯦꯆꯔꯗꯥ (ꯁꯦꯂꯁꯤꯌꯁ ꯗꯤꯒ꯭ꯔꯤ 20-25ꯒꯤ ꯃꯔꯛꯇꯥ) ꯊꯃꯖꯤꯜꯂꯨ꯫ ꯑꯀꯅꯕꯥ ꯑꯁꯥꯕꯥ ꯑꯃꯁꯨꯡ ꯃꯩꯁꯥꯗꯒꯤ ꯂꯥꯞꯅꯥ ꯂꯩꯌꯨ꯫
• ꯃꯇꯝ ꯂꯣꯏꯔꯕꯥ ꯍꯤꯗꯥꯛ-ꯂꯥꯡꯊꯀꯁꯤꯡ ꯁꯤꯖꯤꯟꯅꯒꯅꯨ꯫

ꯃꯇꯝ ꯂꯣꯏꯔꯕꯥ ꯅꯠꯠꯔꯒꯥ ꯃꯊꯧ ꯇꯥꯗꯕꯥ ꯍꯤꯗꯥꯀꯁꯤꯡꯗꯒꯤ ꯂꯥꯄꯊꯣꯛꯅꯕꯒꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯐꯕꯥ ꯄꯥꯝꯕꯩꯗꯤ ꯅꯍꯥꯛꯀꯤ ꯍꯣꯁ꯭ꯄꯤꯇꯥꯜ ꯅꯠꯠꯔꯒꯥ ꯐꯥꯔꯃꯥꯁꯤꯗꯥ ꯂꯩꯕꯥ ‘ꯃꯦꯗꯤꯀꯦꯁꯟ ꯇꯦꯛ-ꯕꯦꯛ ꯄ꯭ꯔꯣꯒ꯭ꯔꯥꯝ’ ꯑꯃꯗꯥ ꯁꯤꯟꯅꯕꯅꯤ꯫ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯃꯗꯨ ꯑꯣꯏꯊꯣꯀꯄꯥ ꯉꯃꯗ꯭ꯔꯕꯗꯤ, ꯃꯗꯨꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯗꯥ ꯍꯪꯕꯤꯌꯨ꯫