Inu kapena munthu amene mumamudziwa mwina mukulandira chithandizo cha khansa. Pa nthawi ya chithandizochi, makamaka chemotherapy, maselo a khansa amawonongeka mofulumira. Ngakhale kuti izi ndi zabwino, maselowa akawonongeka, zinthu zomwe zili mkati mwake, makamaka mankhwala otchedwa uric acid , zimasonkhana mochuluka m'magazi. Kuwonjezeka kwadzidzidzi kwa uric acid sikuli bwino ku impso zathu. Chifukwa chake, pazochitika zotere, madokotala amagwiritsa ntchito mankhwala apadera otchedwa `Rasburicase`. Lero, tiyeni tikambirane za mankhwalawa mwachidule.
Kodi Rasburicase uyu ndi chiyani? Kodi kwenikweni amagwira ntchito yanji?
Mwachidule, Rasburicase (ರಾಸ್-ಬೀರೀ-ಕ್ಸ್) ndi mankhwala omwe amawongolera kuchuluka kwa uric acid m'magazi mwathu. Amagwiritsidwa ntchito makamaka kuchepetsa ndikuletsa kuwonjezeka kwadzidzidzi kwa uric acid m'thupi chifukwa cha chithandizo cha khansa.
Taganizirani mitsempha yathu yamagazi ngati msewu. Maselo a khansa akawonongeka, uric acid imapanga magalimoto ambiri pamsewuwu. Kuyenda kumeneku kungasokoneze kugwira ntchito kwa chiwalo chofunikira kwambiri, impso. Mankhwala otchedwa `Rasburicase` amagwira ntchito ngati apolisi apamsewu, kuchotsa kuchuluka kwa uric acid m'misewu ndikusandutsa mankhwala ena omwe angatulutsidwe mosavuta m'thupi. Izi zimathandiza kuti chithandizo cha khansa chipitirire popanda kuvulaza impso.
Mankhwalawa nthawi zambiri amabwera ngati madzi (infusion) omwe amaperekedwa mumtsempha. Izi zikutanthauza kuti, amaperekedwa m'thupi pang'ono, monga saline. Amaperekedwa kuchipatala kapena kuchipatala moyang'aniridwa ndi madokotala ndi anamwino. `Elitek` ndi dzina lodziwika bwino la mankhwala awa.
Zinthu zomwe muyenera kuuza dokotala wanu musanamwe mankhwalawa
Rasburicase ndi mankhwala amphamvu kwambiri. Chifukwa chake, ndikofunikira kwambiri kudziwitsa dokotala wanu za mbiri yanu yonse ya thanzi musanayambe kulandira chithandizo. Ndikofunikira kwambiri kuwauza ngati muli ndi vuto lililonse mwa izi:
| Matenda kapena mbiri yakale | N’chifukwa chiyani n’kofunika? (Kufotokozera kosavuta) |
|---|---|
| Kusowa kwa G6PD | Imeneyi ndi matenda a majini omwe amakhudza enzyme m'maselo amagazi. Ngati anthu omwe ali ndi vutoli apatsidwa Rasburicase, maselo ofiira amagazi amatha kusweka ndikuyambitsa kuchepa kwa magazi m'thupi. Choncho izi ndizofunikira kwambiri . |
| Kuchepa kwa magazi m'thupi kapena mbiri ya kupereka magazi | Ngati muli kale ndi vuto la kuchepa kwa magazi m'thupi kapena mudapatsidwapo magazi kale, ndikofunikira kudziwitsa dokotala wanu. |
| Matenda osiyanasiyana a ziwengo (Allergies) | Onetsetsani kuti mwauza dokotala wanu ngati muli ndi vuto lililonse la rasburicase, yisiti, mannitol, mankhwala ena, zakudya, kapena utoto. |
| Mimba kapena kuyesa kutenga mimba | Ngati muli ndi pakati kapena mukukonzekera kutenga pakati, ndikofunikira kwambiri kuuza dokotala wanu. |
| Kuyamwitsa | Muyenera kupewa kuyamwitsa pamene mukumwa mankhwalawa komanso kwa milungu iwiri mutasiya kuyamwitsa. Choncho ngati ndinu mayi woyamwitsa, uzaninso dokotala wanu za vutoli. |
Zinthu zoyenera kusamala nazo mukamagwiritsa ntchito mankhwalawa
Ogwira ntchito zachipatala adzakuyang'anirani mosamala kwambiri pamene mukupatsidwa mankhwala awa.
- Kuyezetsa magazi: Pa nthawi ya chithandizo, muyenera kuyezetsa magazi nthawi zonse kuti muwone kuchuluka kwa uric acid m'thupi lanu, momwe mankhwalawo akugwirira ntchito, komanso ngati pali zotsatirapo zina. Izi ndi zachilendo, choncho musadandaule.
- Mankhwala ena: Patsani dokotala wanu mndandanda wathunthu wa mankhwala ena aliwonse, mavitamini, mankhwala azitsamba, ndi zowonjezera zomwe mukumwa. Ena angakhudzidwe ndi mankhwalawa.
- Kwa ana: Mankhwalawa nthawi zina amaperekedwa kwa ana aang'ono ngati mwezi umodzi. Komabe, njira zapadera zotetezera ziyenera kutsatiridwa. Ngati mukupereka mankhwalawa kwa mwana wanu, lankhulani ndi dokotala wa ana za mankhwalawa.
Popeza mankhwalawa amaperekedwa kuchipatala moyang'aniridwa mwachindunji ndi madokotala ndi anamwino, simuyenera kuda nkhawa ndi kumwa mankhwala opitirira muyeso. Ngati mukumva kusasangalala mwanjira iliyonse, dziwitsani namwino kapena dokotala nthawi yomweyo. Adzachitapo kanthu kofunikira pa izi. Ngati mukukayikira kuti pali poizoni wina, mutha kuyimbira National Poisons Information Centre ku Colombo National Hospital kuti akupatseni upangiri.
Kodi zotsatirapo zake za Rasburicase ndi ziti?
Monga mankhwala ena aliwonse, `Rasburicase` ingayambitse zotsatirapo zina mwa anthu ena. Komabe, si aliyense amene amadwala. Chofunika kwambiri ndikunena za zizindikiro zilizonse nthawi yomweyo.
| Kugawa zotsatira zoyipa | |
|---|---|
| Zotsatirapo zoyipa zomwe muyenera kuuza dokotala wanu kapena namwino nthawi yomweyo | |
| Matenda a ziwengo | Kutupa pakhungu, kuyabwa, kutupa kwa nkhope, milomo kapena lilime. |
| Kuvuta kupuma | Kuvuta kupuma, kupweteka pachifuwa kapena kulimba. |
| Mavuto a magazi m'thupi | Milomo kapena zikhadabo zabuluu, kugunda kwa mtima mofulumira kapena kosasinthasintha, kukomoka, kuthamanga kwa magazi, maso kapena khungu kukhala lachikasu. |
| Zizindikiro zina zazikulu | Kukomoka, kutopa kwambiri kapena kutopa, kusokonezeka maganizo. |
| Zotsatirapo zomwe nthawi zambiri sizili zoopsa, koma ziyenera kufotokozedwa kwa dokotala ngati zikupitirira | |
| |
Mndandandawu suli ndi zotsatirapo zonse zomwe zingachitike, kotero ngati mukukumana ndi vuto lililonse lachilendo, musaope kulankhula ndi dokotala wanu za vutoli.
Uthenga Wopita Nawo Kunyumba
- `Rasburicase` ndi mankhwala apadera omwe amaperekedwa kuchipatala kuti achepetse kuchuluka kwa uric acid m'magazi komwe kumawonjezeka chifukwa cha chithandizo cha khansa.
- Musanayambe chithandizo, onetsetsani kuti mwauza dokotala wanu za vuto lanu la G6PD, ziwengo, ndi matenda ena onse.
- Kuyezetsa magazi pafupipafupi n'kofunika kwambiri panthawi ya chithandizo.
- Uzani dokotala wanu kapena namwino nthawi yomweyo ngati mukukumana ndi zizindikiro zilizonse zoopsa za ziwengo, monga kupuma movutikira, kutupa pakhungu, kapena kutupa pankhope.
- Pewani kuyamwitsa kwathunthu mukamamwa mankhwalawa komanso kwa milungu iwiri mutasiya kuyamwitsa.
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