Kodi minofu ya thupi lanu imavina? Kodi imayenda ngati mafunde? Tiyeni tiphunzire za Matenda a Minofu Yogwedezeka!

Kodi mudawonapo kapena kumva minofu yanu ikugwedezeka mwadzidzidzi, ngati kuti ikuyenda ngati mafunde, kapena yonse yagwirizana? Nthawi zina mungaganize kuti ndi chinthu china chabe, koma kwenikweni chikhoza kukhala chizindikiro cha vuto losowa koma lofunika kudziwa. Ndicho chimene tikambirane lero, Rippling Muscle Disease . Musadandaule, tiyeni tisunge zinthu mophweka.

Kodi Matenda a Minofu Yogwedezeka ndi Chiyani?

Mwachidule, Rippling Muscle Disease ndi matenda osowa omwe amakhudza dongosolo lathu la mitsempha ndi minofu. Madokotala amatchanso kuti ndi matenda a mitsempha . Pachifukwa ichi, minofu yathu imachepa pafupipafupi komanso mosalamulirika, zomwe zimapangitsa kuti ikhale yolimba ndipo nthawi zina imakula kwambiri, zomwe zimatchedwa hypertrophy .

Zizindikiro zimenezi nthawi zambiri zimayamba kumapeto kwa ubwana kapena unyamata, koma ndikofunikira kukumbukira kuti vutoli nthawi zina limatha kuonekera pa msinkhu uliwonse.

Kodi zizindikiro za matendawa ndi ziti? Kodi kwenikweni chikuchitika ndi chiyani?

Monga momwe dzinalo likusonyezera, Rippling Muscle Disease imakhudza kwambiri minofu yathu, makamaka minofu yomwe ili pafupi ndi pakati pa thupi lathu (minofu yapafupi) . Makamaka, minofu ya m'ntchafu zathu (quadriceps) ndi yomwe imakhudzidwa kwambiri.

Ngati muli ndi (RMD), zikutanthauza kuti minofu yanu "imasinthasintha" kapena "imasinthasintha mofulumira." Izi zikutanthauza kuti minofu yanu imachita zinthu zachilendo ngakhale mutakhudzidwa pang'ono kapena kukakamizidwa.

Zizindikiro zodziwika bwino za matendawa ndi izi:

• Kugundana kwa minofu: Kunena zoona, minofu yanu imasonkhana pamodzi pamalo amodzi ndipo imakhala ngati "chidutswa".
• Kulimbitsa minofu mobwerezabwereza: Izi zitha kukhala kwa masekondi pafupifupi 30.

Zizindikiro zonsezi nthawi zambiri zimachitika pamene chinachake chagunda ntchafu yanu mwadzidzidzi, monga pamene mwagundana ndi chinthu china. Mwachitsanzo, ngati mwagundana ndi chitseko, minofu ya ntchafu yanu ikhoza kuuma mwadzidzidzi.

Pafupifupi 60% ya anthu omwe ali ndi RMD amamva kugwedezeka kwa minofu. Uku ndi kugwedezeka kwa minofu komwe kumawoneka ngati nyongolotsi zomwe zimakwawa pansi pa khungu. Izi zimatenga pafupifupi masekondi 5 mpaka 20. Izi zimachitika nthawi zambiri mukatambasula minofu.

Zizindikiro zina zomwe zingawonekere ndi izi:

• Kutopa: Sikuti kutopa kokha, komanso kutopa kwambiri komwe kumabwera popanda chifukwa.
• Kupweteka kwa minofu: Kupweteka kwa minofu mwadzidzidzi komanso koopsa komwe kumabweretsa ululu waukulu.
• Kuuma kwa minofu:Zimakhala zovuta kupindika kapena kumasula nyama.

Zizindikirozi zimatha kukulirakulira atatha kuchita masewera olimbitsa thupi kwambiri kapena kuzizira. Mwa anthu ena, minofu ina imatha kukula kwambiri (hypertrophy) ndipo kayendedwe kawo kangasinthe pang'ono (mayendedwe osazolowereka) .

Kodi matendawa ndi opweteka?

Inde, (Rippling Muscle Disease) ingayambitse kupweteka kwa minofu. Makamaka minofu ikapitirizabe kufooka, ululu umakhala waukulu kwambiri ngati upitirira kwa kanthawi. Komanso, minofu ikagwedezeka (kupweteka kwa minofu) ululu umachitika. Tangoganizirani momwe zingakhalire zovuta ngati minofu ya mwendo wanu ikanakhala yolimba nthawi zonse.

Kodi n’chiyani chimayambitsa matenda a Rippling Minofu?

Matenda a Minofu Yogwedezeka nthawi zambiri amayamba chifukwa cha kusintha kwa majini otchedwa CAV3, omwe timalandira kuchokera kwa makolo athu. Jini ya CAV3 imauza matupi athu kuti apange puloteni yotchedwa caveolin-3 . Puloteni iyi imapezeka mu nembanemba yozungulira maselo a minofu. Ofufuza amakhulupiriranso kuti puloteni iyi imathandiza kuwongolera kuchuluka kwa calcium , komwe kumathandiza minofu kukokana ndi kutambasuka.

Kwa anthu omwe ali ndi RMD, kusintha kwa majini a CAV3 kumayambitsa kuchepa kwa kupanga kwa puloteni ya caveolin-3. Ofufuza amakhulupirira kuti kusowa kwa mapuloteni kumeneku kumapangitsa kuti calcium m'maselo a minofu isayende bwino. Zotsatira zake, minofu imachepa modabwitsa chifukwa cha kukankhira pang'ono kapena kukoka.

Pali mitundu ingapo ya kusintha kwa majini mu jini iyi (CAV3). Matenda okhudzana ndi glands ya nyama omwe amayamba chifukwa cha kusintha kwa majini awa amatchedwa (caveolinopathies) . Kuwonjezera pa (RMD), matenda ena angapo omwe ali m'gululi ndi awa:

• (Autosomal dominant limb-girdle muscular dystrophy) (yomwe kale inkadziwika kuti LGMD1C)
• (Hypertrophic cardiomyopathy) (Iyi ndi matenda a mtima)
• (Isolated hyperCKEmia) (Mkhalidwe womwe enzyme creatine kinase m'magazi imakwera)
• (CAV3-related distal myopathy) (matenda omwe amakhudza minofu m'miyendo yakutali)

Muzochitika izi, nthawi zina zizindikiro monga kupweteka kwa minofu, monga makwinya, zimatha kuwoneka mu (RMD).

Komanso, mtundu wa Rippling Muscle Disease womwe umapezeka ndi matenda a autoimmune a Myasthenia gravis wanenedwa. Anthu amenewo alibe kusintha kwa majini a CAV3. Izi zikutanthauza kuti chitetezo chawo cha mthupi chimaukira ulusi wa minofu.

Kodi timalandira bwanji matenda a Rippling Minofu?

Nthawi zambiri, Rippling Muscle Disease imachokera ku autosomal dominant pattern . Mwachidule, izi zikutanthauza kuti mutha kudwala matendawa ngati mutalandira kopi imodzi ya jini yosinthidwa ya CAV3 kuchokera kwa amayi kapena abambo anu. Zitha kuchitika ngakhale mutakhala ndi jini imodzi yokha.

Nthawi zina, RMD imatha kutengedwa ngati cholowa mu autosomal recessive pattern . Izi zikutanthauza kuti muyenera kulandira makope awiri a jini ya CAV3 yosinthidwa, kuchokera kwa amayi ndi abambo anu.

Anthu omwe ali ndi Rippling Muscle Disease mu mawonekedwe a autosomal recessive akhoza kukhala ndi zizindikiro zoopsa pang'ono kuposa omwe ali ndi mawonekedwe a autosomal dominant.

Kawirikawiri, RMD imatha kuchitika chifukwa cha kusintha kwa majini kwatsopano, popanda mbiri ya banja. Izi zikutanthauza kuti vuto la majini limeneli lingachitike m'thupi la munthu koyamba, popanda kulandira kuchokera kwa makolo ake.

Kodi madokotala amazindikira bwanji matenda a Rippling Muscle Disease molondola?

Madokotala amagwiritsa ntchito mayeso ndi njira izi kuti adziwe matenda a Rippling Muscle Disease, koma si aliyense amene ayenera kuchita zonsezi.

• Mbiri ya zachipatala: Dokotala adzakufunsani za zizindikiro zanu komanso ngati pali aliyense m'banja mwanu amene wakhalapo ndi RMD kapena matenda ena a caveolinopathy.
• Kuyezetsa thupi ndi mitsempha: Dokotala adzayang'ana momwe minofu yanu ndi mitsempha yanu zimagwirira ntchito.
• Kuyezetsa magazi a Creatine kinase: Pamene minofu yawonongeka, enzyme iyi (creatine kinase) imawonjezeka m'magazi.
• Electromyography (EMG): Izi zimayesa mphamvu yamagetsi ya ulusi wa minofu.
• Kufufuza minofu: Kachidutswa kakang'ono ka minofu kamatengedwa ndikuyang'aniridwa pogwiritsa ntchito maikulosikopu.
• Mayeso a ma antibodies: Mayesowa amachitika kuti aone ngati (RMD) ndi autoimmune.
• Kuyesa majini: Iyi ndiyo njira yabwino kwambiri yodziwira ngati pali kusintha kulikonse mu jini ya (CAV3).

Mayeso amenewa amathandiza kuchotsa matenda ena omwe ali ndi zizindikiro zofanana ndi zimenezi ndipo amatsimikizira Matenda a Minofu Yogwedezeka.

Pa nthawi yodziwira matenda, dokotala wanu angakutumizireni kwa katswiri, monga katswiri wa mitsempha kapena katswiri wa majini .

Kodi mankhwala ochizira izi ndi otani?

Chithandizo cha Rippling Muscle Disease chimadalira ngati ndi majini kapena chitetezo chamthupi.

Chithandizo cha majini:

Izi makamaka zimaphatikizapo kuchepetsa zizindikiro ndikupereka upangiri wa majini . Ngati kugwedezeka kapena kuchepa kwa machende kuli koopsa kwambiri, mankhwala ena angathandize. Mankhwala oterewa ndi awa:

• (Dantrolene): Ichi ndi mankhwala opumulira minofu.
• (Otsutsana ndi njira ya calcium):Izi ndi mankhwala omwe amaletsa njira za calcium.
• Benzodiazepines: Izi zimachepetsa minofu ndi kuchepetsa nkhawa.

Chithandizo cha Autoimmune:

Izi zitha kuchiritsidwa ndi chithandizo cha immunosuppressive therapy , kapena ngati muli ndi thymoma (chotupa mu thymus gland), opaleshoni yochotsa thymus gland (thymectomy) ikhoza kuchitidwa.

Kodi tingaletse izi (Rippling Minofu Disease) kuti zisakule?

Popeza matenda a Rippling Muscle Disease nthawi zambiri amakhala a majini, palibe chomwe tingachite kuti tipewe matendawa. Si chinthu chomwe tingathe kuchiletsa.

Komabe, ngati mukuda nkhawa ndi chiopsezo chopatsira mwana wanu RMD kapena matenda ena a majini musanakhale ndi mwana, ndikofunikira kwambiri kulankhula ndi dokotala wanu za upangiri wa majini kuti mumvetsetse bwino.

Kodi ndiyenera kupita kwa dokotala liti?

• Ngati zizindikiro za RMD yanu zikuipiraipira , kapena ngati zikuchitika pafupipafupi , onetsetsani kuti mwalankhula ndi dokotala wanu.
• Ngati wina m'banja mwanu wapezeka ndi Rippling Muscle Disease posachedwapa, funsani dokotala wanu ngati inu kapena achibale ena muli pachiwopsezo chotenga matendawa.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala wanga?

Zingakhale zothandiza kufunsa dokotala wanu mafunso awa:

• Kodi ndingachite chiyani kuti ndithetse zizindikiro zanga?
• Ndi njira iti yothandizira yomwe ndi yabwino kwa ine?
• Kodi ana anga angalandire matenda a Rippling Muscle Disease kuchokera kwa ine?
• Kodi anthu ena a m'banja langa ayenera kuyezedwa matenda a Rippling Muscle Disease?

Mukafunsa mafunso awa, mudzatha kumvetsetsa bwino nkhaniyi.

Kodi Matenda a Minofu Yogwedezeka Amakhudza Mtima?

Matenda a Minofu Yogwedezeka sakhudza mtima mwachindunji. Komabe, RMD ndi hypertrophic cardiomyopathy zonse zimachitika chifukwa cha kusintha kwa majini omwewo (CAV3), kotero pali mgwirizano pakati pa matenda awiriwa. Ngakhale kuti ndi osowa kwambiri, kusintha kwa majini a CAV3 kumatha kukhudza minofu ya mtima ndi minofu ina m'thupi. Koma ndi osowa kwambiri.

Kodi (Matenda a Minofu Yogwedezeka) ndi oopsa?

Matenda a Minofu Yogwedezeka si oopsa kwenikweni. Izi zikutanthauza kuti, saika moyo pachiswe. Komabe, zizindikiro za (RMD) monga kupweteka kwa minofu monga makwinya zingakhalenso chizindikiro cha matenda ena (caveolinopathies) omwe amayamba chifukwa cha kusintha kwa majini (CAV3) komwe kwatchulidwa pamwambapa.

Mwa matenda a caveolinopathies, milandu yoopsa ya autosomal dominant limb-girdle muscular dystrophy ndi hypertrophic cardiomyopathy nthawi zina ingakhale yoopsa.

Ndizachibadwa kumva kutopa kwambiri mukapezeka ndi matenda a majini, makamaka omwe sachitika kawirikawiri. Koma kumbukirani kuti gulu lanu lachipatala lidzakhalapo kuti likufotokozereni za Rippling Muscle Disease, kukuuzani momwe ingakukhudzireni, ndikukuthandizani kupeza njira yabwino yothetsera zizindikiro zanu.

Zinthu zofunika kwambiri kukumbukira (Uthenga Wopita Nawo Kunyumba)

Chabwino, tsopano mwamvetsa zomwe takhala tikulankhula (Rippling Muscle Disease). Mwachidule:

• Matenda a Minofu Yogwedezeka ndi matenda osowa kwambiri a minofu omwe amadziwika ndi kugwedezeka kwa minofu, makwinya, kuuma, ndi kupindika.
• Kawirikawiri, izi zimachitika chifukwa cha zifukwa za majini (gene ya CAV3) . Nthawi zina, pakhoza kukhalanso zifukwa zodzitetezera ku matenda a autoimmune.
• Imeneyi si matenda oopsa , koma matenda ena a m'mapapo omwe amabwera chifukwa cha matendawa akhoza kukhala oopsa.
• Ngati muli ndi zizindikiro izi, musachite mantha ndipo funsani upangiri kwa dokotala . Chofunika kwambiri ndikupeza matenda olondola ndikupeza chithandizo ndi upangiri wofunikira.
• Uphungu wa majini ungakhale wothandiza kwambiri pazochitika ngati izi.

Ngati mukufuna kudziwa zambiri za izi, kapena ngati mukuganiza kuti muli ndi zizindikiro izi, chonde onani dokotala. Musachite mantha, pali njira zothetsera mavuto onse.

Matenda a Minofu Yogwedezeka , kugwedezeka kwa minofu, kupindika kwa minofu, jini la CAV3, kupweteka kwa minofu, matenda a majini, matenda odziteteza ku matenda a autoimmune