Icyo ugomba kumenya kuri androgens!

Ese wigeze wumva ibya androgens? Wenda yego, wenda sibyo. Ariko ni itsinda ry'imisemburo iri mu mibiri yacu yose kandi ni ingenzi cyane ku mikurire yacu y'imibonano mpuzabitsina n'ubuzima bwacu. Izi androgens ni nk'abakozi bato bakora inyuma y'ibishushanyo mbonera mu mibiri yacu. Uyu munsi, turazivugaho mu buryo bworoshye ushobora kumva.

Mu magambo make, androgens ni ubwoko bw'imisemburo y'ibitsina. Ni yo ituma tuba abantu bakuru, kandi inafasha mu buzima bw'imyororokere yacu no gukura kw'imibiri yacu. Ushobora gutekereza ko abagabo ari bo bonyine bayigira. Ariko mu by'ukuri, twese, twaba abagabo cyangwa abagore, dufite androgens mu mibiri yacu. Ariko, ikorwa mu buryo busanzwe ku bagabo ku rugero rwo hejuru. Testosterone, benshi muri twe twumvise, nayo ni androgen ikomeye.

Ubu ushobora kwibaza aho iyi misemburo ikomoka. Androgens ikorwa ahanini n'udusabo tw'intanga ngabo n'intanga ngabo mu buryo bw'imyororokere bw'abagore. Byongeye kandi, iyi misemburo ikorwa n'uturemangingo tw'intanga ngabo tuba hejuru y'impyiko zacu. Androgens ntabwo ziba gusa. Zikora neza cyane mu kubungabunga iterambere ry'imibonano mpuzabitsina n'ubuzima bwacu muri rusange. Urugero rwazo rushobora guhinduka umunsi wose. Nanone, iyi misemburo irahinduka mu byiciro bitandukanye by'ubuzima bwacu, nko mu gihe cy'ubugimbi n'ubwangavu.

Ni ubuhe bwoko bwa androgens buriho?

Nkuko twabivuze mbere, testosterone niyo androgen nyamukuru twese dufite. Izindi androgen nyinshi zifasha mu gukora izindi hormone. Urugero, androgen zikurikira zifasha mu gukora testosterone na estrogen:

• Androstenedione
• Dehydroepiandrosterone (DHEA)
• DHEA sulfate (DHEA sulfate - DHEAS)

Indi androgen ni dihydrotestosterone (DHT) . Uko ugenda ukura, umubiri wawe uhindura hafi 10% bya testosterone yawe muri DHT buri munsi. Byongeye kandi, hari ubundi bwoko bwinshi bwa androgen hamwe n'ibindi bintu byinshi bifitanye isano na androgen. Uburyo imibiri yacu ikoresha iyi hormones buragoye cyane, nk'imashini nini.

Ni iyihe serivisi androgens itanga ku mibiri yacu?

Androgens muri twese, hatitawe ku gitsina, zidufasha muri ibi bintu:

• Ubucucike bw'amagufwa: Ibi ni ingenzi kugira ngo amagufwa yacu akomeze gukomera.
• Gukura kw'imitsi: Ibi birakenewe kandi kugira ngo imitsi ikure.
• Ubugimbi: Izi ni zo mpinduka z'ibanze zibaho kuva mu bwana kugera ku bukuru.
• Gukora uturemangingo dutukura tw'amaraso (Erythropoiesis): Binagira uruhare mu gukora uturemangingo dutukura tw'amaraso mu mubiri wacu.
• Irari ry'imibonano mpuzabitsina n'imikorere yayo: Ibi bigira ingaruka ku iterambere ry'amarangamutima y'imibonano mpuzabitsina n'ibikorwa by'imibonano mpuzabitsina.

Ni iki kibera abagabo bafite androgens?

Androjeni mu mubiri w'umugabo zigira uruhare muri ibi bikurikira:

• Ijwi ryimbitse (kwagura ijwi): Ijwi ryoroshye wari ufite ukiri umwana rirahinduka, maze ijwi ry’umugabo rikagaragara kubera ibi. Tekereza, umuhungu w’inshuti yawe ahita ahindura ijwi rye, maze ukibwira uti "Muvandimwe, ubu ni umuhungu mukuru," si byo se? Impamvu yabyo ni androgens.
• Kuba muremure: Iyi misemburo igira ingaruka no ku burebure.
• Ukwiyongera k'umusatsi mu maso, ku mutwe, mu gituza, mu kwaha no mu myanya ndangagitsina: Ibintu nko kumera ubwanwa no kumera k'umusatsi mu gituza.
• Iterambere ry'intanga: Ibi ni ingenzi kugira ngo intanga zikoreshwe mu gukora umwana.

Izi kamere z'umubiri akenshi zitangira mu gihe cy'ubugimbi. Ariko testosterone ifite imirimo itandukanye mu byiciro bitandukanye by'ubuzima. Uko ugenda ukura, urugero rwa testosterone yawe rugabanuka uko ugenda usaza.

Ni gute androgens zigira ingaruka ku bagore?

Ku bagore, izindi shimi zihindura testosterone ya androgene ikayihindura estradiol, ubwoko bwa hormone ya estrogen . Iyi estradiol:

• Iterambere ry'imiterere y'imibonano mpuzabitsina mu gihe cy'ubugimbi: urugero, iterambere ry'amabere no kwaguka kw'ikibuno.
• Igenzura imihango: Ifasha mu kugumana imihango isanzwe.
• Bifasha mu gusama no gutwita: Ibi ni ingenzi mu gusama no kubyara neza.
• Igabanya gutakaza amagufwa - Osteoporose: Ifasha kugabanya ibyago byo kurwara osteoporose , ikaba ari indwara ibaho iyo amagufwa avunitse, cyane cyane uko tugenda dusaza.

Ingano ya estradiol mu mubiri wawe irahinduka mu bihe bitandukanye by'ubuzima bwawe. Nyuma yo gucura, ari nabwo imihango yawe ya buri kwezi ihagarara, umubiri wawe ntukora estradiol nyinshi nk'izo.

Ni ibihe bibazo abagabo bahura na androgens?

Abagabo bakunze kwibasirwa cyane n'indwara yitwa hypogonadism y'abagabo, ari yo kugabanuka k'urugero rwa androgen, cyangwa testosterone. Ibi bishobora gutuma ubushake bwo gukora imibonano mpuzabitsina bugabanuka ndetse bigatuma ubushake bwo gukora imibonano mpuzabitsina budakora neza.Ibimenyetso nka: Niba ufite ikibazo nk'iki, ni ngombwa cyane kuvugana na muganga utiriwe ugihisha cyangwa ngo ugire impungenge.

Kuri bamwe, androgens zishobora gutera kanseri ya prostate . Muri ibyo bihe, ushobora gukenera gufata imiti kugira ngo ugabanye umusaruro w’uturemangingo twa androgens mu mubiri. Abaganga bita ubu buryo bwo kuvura Androgen Deprivation Therapy (ADT) .

Androgens – cyane cyane DHT (Dihydrotestosterone) – na zo zifitanye isano n’ubusa bw’abagabo , indwara yitwa androgenic alopecia . Iyi misemburo inagira uruhare mu busa bw’abagabo benshi bita ‘waxiness’.

Ni ibihe bibazo abagore bafite ku bijyanye na androgens?

Abagore bakunze kwibasirwa n'ibibazo byo kwiyongera kwa androgen (hyperandrogenism) . Impamvu nyamukuru ibitera ni indwara yitwa Polycystic Ovary Syndrome (PCOS) . Iyi PCOS ni ikintu kigaragara mu bagore benshi muri iyi minsi. Ese wari uzi ko PCOS rimwe na rimwe ishobora gutera gutinda gusama? Ni gake cyane, androgen ishobora kwiyongera bitewe n'ibibyimba mu ngirabuzimafatizo z'intanga cyangwa intanga.

Abantu barwaye PCOS, cyangwa abafite androgens nyinshi, bashobora kugira ibimenyetso nk'ibi bikurikira:

• Ibiheri: Ibiheri bigaragara mu maso, mu gituza no mu mugongo. Hari igihe ibi biheri bishobora kubabaza cyane.
• Amenorrhea cyangwa imihango idasanzwe: Guhera mu mihango bitabaye mu gihe gikwiye, cyangwa bigatinda mu mezi menshi.
• Gukura cyane k'umusatsi (hirsutism): Gukura k'umusatsi udakenewe ku kananwa, mu gituza no mu nda, nko ku bwanwa. Ibi bishobora no kugira ingaruka ku bagore benshi mu mitekerereze.
• Umuvuduko w'amaraso ukabije na cholesterol nyinshi.
• Ingorane zo kubyara (Ubugumba).
• Umubyibuho ukabije: Kuba ufite umubyibuho ukabije.

Androgens – cyane cyane DHT (Dihydrotestosterone) – ishobora no kugira ingaruka ku burwayi bw’abagore. Hari abagore bamwe na bamwe bagira ikibazo cyo gutakaza umusatsi n’umutwe w’inyuma, si byo se? Iyi hormone na yo igira ingaruka kuri ibyo.

Ni ibihe bibazo bishobora kuvuka bitewe n'urugero rwa androgen mu bana bato?

Ibibazo ku rugero rwa androgen mu bana bishobora gutuma abana batinda mu bugimbi cyangwa bagatangira kuba ingimbi.Yego, birashoboka. Hari impamvu nyinshi zishobora gutuma buri kimwe muri ibi kibaho. Urugero, bamwe mu bana bagaragaza ibimenyetso by'ubugimbi mbere cyane y'abandi. Kandi bamwe ntibagera mu bugimbi ndetse na nyuma yo kugera mu bugimbi. Ibi byombi ni indwara zisaba ubuvuzi.

Urugero rwa Androgen narwo rufitanye isano n'indwara zitwa indwara zo gukura kw'imibonano mpuzabitsina . Ibi bivuga itsinda ry'indwara zigera kuri 60 zitandukanye aho umuntu aba afite imiterere y'abagabo n'abagore. Izi ni indwara zigoye, bityo zikenera kwitabwaho by'umwihariko n'abaganga.

Ni gute abaganga bapima urugero rwa androgen?

Kugira ngo barebe niba umugore afite urugero rwo hejuru rwa androgen, abaganga bakoresha ikizamini cyitwa Free Androgen Index (FAI) . FAI ipimwa hakoreshejwe ikizamini cy'amaraso hanyuma igapima ibi bikurikira:

• Testosterone yose hamwe
• Testosterone y'ubuntu
• Globulin ihuza imisemburo y'igitsina (SHBG)

SHBG ni poroteyine itwara androgens (nka testosterone na DHT) na estrogen mu maraso. Muganga wawe azabara urugero rwa androgens yawe agereranya urugero rwa testosterone yawe yose hamwe na SHBG.

Ku bagabo, abaganga bakunze gutumiza ibizamini by’amaraso bya testosterone kugira ngo barebe niba testosterone iri hasi.

Ariko ibuka ko ibi bipimo by'amaraso byonyine bitashobora kukubwira byose. Muganga wawe azafata icyemezo ashingiye ku bintu byinshi, harimo ibimenyetso byawe n'isuzuma rya muganga.

None se, ni ubuhe butumwa dukwiye kujyana mu byo twavuze byose?

Androjeni ni ingenzi ku buzima bw'imyororokere n'imibereho myiza muri rusange ya twese, abagore, abagabo, abato n'abakuru. Ariko kugira ngo ibi bikore neza, hakenewe uburinganire bukwiye . Nk'umunzani, iyo uremereye cyane ku ruhande rumwe, haba hari ikibazo. Niba ari muto cyane, haba hari ikibazo; niba ari mwinshi cyane, haba hari ikibazo.

Niba ufite ibimenyetso by'urugero rwa androgen ruri hasi cyangwa ruri hejuru, urugero, nk'uko byavuzwe mbere, kubura ubushake bwo gukora imibonano mpuzabitsina, kugorwa no kubona ubushake bwo guhagarara ku bagabo, imihango idahoraho, gukura k'umusatsi cyane, ibiheri ku bagore, cyangwa gutinda cyangwa mu gihe cy'ubwangavu ku mwana, menya neza ko wagiye kwa muganga kugira ngo akugire inama . Hanyuma muganga ashobora gukora ibizamini bikenewe akamenya neza icyateye ibimenyetso byawe. Ntugahangayike, akenshi hari uburyo bwiza bwo kuvura ibi.

Wibuke ko uzi umubiri wawe neza. Iyo ubonye impinduka cyangwa ibitagenda neza, ni byiza gushaka inama kwa muganga aho kubyirengagiza.

Androjeni , Testosterone, Imisemburo, Ubuzima bw'imyororokere, PCOS, Ubuzima bw'abagabo, Ubuzima bw'abagore