Ngaba wakha waziva ngathi amhlophe emehlweni naselusu lwakho ajika abe tyheli kancinci? Kuyoyikisa ukubona loo nto, akunjalo? Usenokucinga ukuba luhlobo oluthile lwesifo sesibindi. Esinye isizathu esinokubakho sesi sifo sisifo esibizwa ngokuba yiGilbert's syndrome. Kodwa ungoyiki xa usiva igama, alinabungozi njengoko unokucinga. Enyanisweni, sisifo semfuza kunokuba sisifo.
Ngamafutshane, yintoni isifo sikaGilbert?
Isifo sikaGilbert sisifo esixhaphakileyo esichaphazela iintsapho zethu, oko kukuthi, sibangelwa lufuzo. Umntu onesifo esinjalo unenkunkuma eninzi kakhulu ebizwa ngokuba yi-bilirubin egazini lakhe.
Ngoku mhlawumbi uyazibuza ukuba yintoni i-bilirubin. Kulula kakhulu. Iiseli ezibomvu zegazi emzimbeni wethu nazo zinexesha lobomi. Xa elo xesha lobomi liphelile, ziyaqhekeka. I-Bilirubin yipigment etyheli, okanye imveliso engcolileyo, eyenzeka xa iiseli ezibomvu zegazi ziqhekeka. Ngokwesiqhelo, isibindi sethu sithatha le bilirubin, siyicubungule, size siyisuse emzimbeni nge-bile.
Kodwa kubantu abane-Gilbert's syndrome, isibindi asivelisi ngokwaneleyo i-enzyme ekhethekileyo eyenza lo msebenzi. Ngoko ke i-bilirubin ayinakususwa ngokupheleleyo, kwaye enye yayo ihlala egazini. Xa inqanaba le-bilirubin egazini lisanda, ngamanye amaxesha amehlo nolusu luba tyheli. Sikwabiza oku ngokuba yi-jaundice .
Into ebalulekileyo kukuba i-Gilbert's syndrome ayisiyongxaki. Ayifuni unyango. Ayizukubangela umonakalo ohlala ixesha elide ebomini bakho.
Yintoni unobangela wale meko?
Oku kungenxa yomahluko omncinci kwiijini zethu. Njengokuba sizuza izinto ezifana nombala wolusu kunye nokwakheka kweenwele kubazali bethu, oku kuyinyaniso.
Kukho ijini emzimbeni wethu ebizwa ngokuba yi -UGT1A1 . Le jini isiyalela ukuba senze i-enzyme yesibindi endiyikhankanyileyo ngaphambili ecoca i-bilirubin. I-Gilbert's syndrome ibangelwa kukuguquka okuncinci kwesi jini.
Ukuze ube nale meko, kufuneka ube neekopi ezimbini zejini eguquliweyo. Oku kuthetha ukuba kufuneka uyizuze njengelifa ijini kumama wakho nakutata wakho . Nangona kunjalo, nokuba ninayo yomibini ijini, ayinguye wonke umntu oza kubonisa iimpawu zesifo sikaGilbert. Kwakhona, le meko ixhaphake kakhulu kumadoda kunakwabasetyhini.
Zithini iimpawu zesifo sikaGilbert?
Enyanisweni, uninzi lwabantu abane-Gilbert's syndrome abanazo iimpawu konke konke . Banee-enzymes zesibindi ezaneleyo zokulawula amanqanaba e-bilirubin emizimbeni yabo.
Uphawu oluphambili kwaye ngamanye amaxesha kuphela kukutyheli kwamehlo nolusu, okwaziwa ngokuba yi-jaundice. Ukuba ufumana ukutyheli kwamehlo, kubalulekile ukubona ugqirha ukuze akuhlole , njengoko kunokubakho ezinye izizathu.
Abanye abantu banokufumana ezi mpawu zilandelayo kunye nokutyheli kwamehlo:
- Ukuhlanza kunye nokuphazamiseka kwesisu
- Ukungonwabi kwesisu
- Ndiziva ndidiniwe kakhulu (ndidinwe kakhulu)
- Umchamo omnyama
Kutheni amehlo am ejika abe tyheli ngamanye amaxesha, hayi rhoqo?
Lo ngumbuzo olungileyo. Kukho izinto ezithile ezinokubangela ukuba amanqanaba ethu e-bilirubin anyuke. Kulapho sihlala sibona khona ukuba tyheli kwamehlo.
| Amatyala apho amanqanaba e-bilirubin enyuka kwaye i-jaundice inokwenzeka | |
|---|---|
| Uxinzelelo | Ngenxa yeemviwo, iingxaki emsebenzini, njl. |
| Ukuphelelwa ngamanzi emzimbeni | Ukungaseli manzi aneleyo emzimbeni. |
| Ukutsiba ukutya | Andityi isidlo sakusasa okanye sasemini. |
| Ukuzilolonga kakhulu | Ukwenza umthambo onzima kakhulu, njengokuqubha. |
| Iimeko ezichaphazelayo | Xa ufumana isifo esifana nomkhuhlane okanye umkhuhlane. |
| Ukusela utywala | Utywala bubeka umthwalo ongaphezulu kwisibindi. |
| Amanye amayeza | Ukuthatha amayeza athile achaphazela isibindi. |
| Ukuya exesheni kwabasetyhini | Ngexesha leentsuku zomjikelo wenyanga wokuya exesheni. |
Ungayibona njani le meko?
Nangona i-Gilbert's syndrome yimeko yokuzalwa, idla ngokufunyaniswa kubantu abakwiminyaka yabo yama-20 okanye engama-30. Naloo nto yenzeka ngengozi.
Khawuthelekelele ukuba uvavanywa igazi ngesizathu esithile. Emva koko ugqirha wakho ubona ukuba inqanaba le-bilirubin egazini lakho liphezulu kancinci kunesiqhelo. Emva koko unokukrokrela ukuba unesifo sikaGilbert.
Emva koko, ukuqinisekisa ukuba akukho ezinye izifo zesibindi eziyingozi, ugqirha unokwenza iimvavanyo ezininzi, ezifana nezi:
- Uvavanyo Lokusebenza Kwesibindi (LFT): Olu luvavanyo lwegazi oluqhelekileyo.
- I-Ultrasound yesibindi: Ukujonga ezinye iingxaki zesibindi.
- Uvavanyo lweGene: Qinisekisa ukuba unayo na i-UGT1A1 gene mutation.
- I-Biopsy yesibindi: Oku akwenzeki rhoqo.
Unyango kunye noko sinokukwenza ngokwethu
Iindaba ezimnandi zezokuba uninzi lwabantu abane-Gilbert's syndrome abadingi naluphi na unyango , kwaye ukuba tyheli kwamehlo akho akuyi kubangela naziphi na iingxaki ezihlala ixesha elide.
Ngoko ke into ekufuneka siyenze kukuhlala kude kangangoko sinako kwizinto endizikhankanyileyo ngaphambili ezinyusa amanqanaba e-bilirubin.
- Musa ukutsiba ukutya, ingakumbi xa uzila ukutya.
- Sela amanzi amaninzi kunye nolwelo. Musa ukuvumela umzimba wakho uphelelwe ngamanzi emzimbeni.
- Lawula uxinzelelo. Yenza into ephumzayo efana nokucamngca, ukumamela umculo, okanye ukwenza into oyithandayo.
- Lala kakuhle. Lala ubuncinane iiyure ezisi-7-8 ngosuku.
- Nciphisa okanye uyeke ngokupheleleyo ukusela utywala .
- Kuphephe ukwenza umthambo onzima. Ukuzilolonga okuphakathi kulungile, kodwa ungazibhokoxi ngaphezu kwemida yakho.
Oko kufuneka ukwazi xa usebenzisa amayeza!
Oku kubaluleke kakhulu. Ukuba unesifo sikaGilbert, kufuneka uqaphele oku ngaphambi kokuba uthathe naliphi na iyeza elitsha.
I-enzyme efanayo ecoca i-bilirubin kwisibindi sethu ikwanceda ekuqhekekeni nasekususeni amanye amayeza emzimbeni. Ngoko ke, ngenxa yokuba unesifo sikaGilbert, umsebenzi waloo enzyme uyancipha kancinci. Ngoko ke, ukuba uthatha amayeza anjalo, aqokelelana emzimbeni ngokugqithisileyo.Umngcipheko weziphumo ebezingalindelekanga uphezulu.
Umzekelo, jonga la mayeza:
- I-Acetaminophen - (Iqulethe iPanadol, iParacetamol)
- Irinotecan - iyeza elisetyenziselwa ukunyanga umhlaza
- Amanye amayeza e-HIV kunye ne-hepatitis C (i-Protease inhibitors)
Ngoko ke, nokuba usebenzisa amayeza amatsha anjani, qiniseka ukuba uxelela ugqirha wakho ukuba unesifo sikaGilbert. Angakunika amayeza akhuselekileyo afanelekileyo kuwe. Ungaze uthathe naliphi na iyeza elingabhalwanga ngugqirha okanye ulisebenzise ngaphezu kwedosi ecetyiswayo.
Umyalezo Wokuya Ekhaya
- Isifo sikaGilbert sisifo esiqhelekileyo, esingoyikisiyo, esidluliselwa kwilifa. Asisisifo esoyikwayo.
- Amehlo nolusu luba tyheli (i-jaundice) ngenxa yamanqanaba aphezulu e-bilirubin egazini. Oku kudla ngokubangelwa luxinzelelo okanye ukugula.
- Akukho nyango luthile lufunekayo koku. Eyona nto ingcono onokuyenza kukuphepha izinto ezonyusa amanqanaba e-bilirubin.
- Okubaluleke kakhulu: Ukuba unesifo sikaGilbert, qiniseka ukuba uxelele ugqirha wakho ngaphambi kokuba uthathe naluphi na unyango olutsha.
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