Ingabe imithi oyiphuzayo ingasongela impilo? Ake sixoxe nge-Serotonin Syndrome

Ingabe ungumuntu ophuza imithi yokucindezeleka, i-migraines, noma ubuhlungu obukhulu? Noma ingabe uphuza imithi kodokotela abaningana ngenxa yesifo esifanayo? Khona-ke le ndaba izoba ibaluleke kakhulu kuwe. Namuhla sikhuluma ngesimo esingase senzeke emzimbeni wethu ngenxa yezinhlobo ezithile zemithi, ezingaba yingozi empilweni uma zingaqondwa kahle. Lokhu sikubiza ngokuthi 'i-Serotonin Syndrome' . Ungakhathazeki, uma sazi kahle ngalokhu, singagwema ingozi enkulu.

Kalula nje, iyini i-Serotonin Syndrome?

Ukuze siqonde lokhu, sidinga kuqala ukwazi ukuthi iyini 'iSerotonin'. Cabanga ngayo njengesithunywa esincane esithwala imiyalezo phakathi kobuchopho bethu kanye nomzimba wethu wonke. Kwezokwelapha, lezi zithunywa zamakhemikhali sizibiza ngokuthi 'ama-neurotransmitter'. ISerotonin nayo iyi-neurotransmitter ebaluleke kakhulu emzimbeni wethu, ilawula izinto eziningi ezifana nemizwa yethu, ukulala, kanye nesifiso sokudla.

Ngokuvamile, uma uthatha umuthi onikezwe udokotela, izinga le-serotonin emzimbeni liyalingana. Kodwa-ke, uma ngesizathu esithile leli khemikhali elibizwa ngokuthi i-serotonin landa kakhulu emzimbeni wethu , okungukuthi, uma liqongelela ngenani umzimba ongakwazi ukuliphatha, ukusabela komzimba wethu kulo kubizwa ngokuthi 'i-serotonin syndrome'. Lokhu kungaba ukusabela okuyingozi okubangelwa uhlobo lomuthi (ukusabela kwezidakamizwa).

Ubani onamathuba amaningi okuthola lesi simo?

Eqinisweni, noma ubani wanoma yimuphi ubudala osebenzisa imithi, izithasiselo, noma izidakamizwa ezingekho emthethweni ezithinta amazinga e-serotonin usengozini. Lesi simo sivame ukubonakala ezimweni ezinjengalezi:

• Uma uqala umuthi omusha: Lapho nje uqala umuthi omusha owandisa amazinga e-serotonin.
• Uma ukhuphula umthamo womuthi: Uma udokotela wakho enyusa umthamo womuthi osuwusebenzisa kakade.
• Uma usebenzisa imithi eminingana ndawonye: Lena imbangela eyingozi kakhulu futhi evamile. Cabanga nje, unesifo samalunga. Uthatha umuthi wokuqeda izinhlungu kudokotela oyedwa ngenxa yalokho. Okwamanje, ngoba ukhathazekile kancane, ubona omunye udokotela bese uthatha umuthi walokho futhi. Kodwa awumtsheli udokotela wokuqala ngomuthi wesibili, noma udokotela wesibili ngomuthi wokuqala. Lokhu kwenzeka lapho kunethuba elikhulu lokusebenzisa imithi emibili ekhulisa i-serotonin ndawonye ngokungazi bese kuba nomthelela kulesi simo.
• Uma uphuza umuthi omningi kakhulu: Uma uphuza umuthi omningi kunomthamo onqunyiwe, ngamabomu noma ngengozi.

Ziyini izimpawu? Sikubona kanjani lokhu?

Izimpawu ze-serotonin syndrome zingahluka kuye ngomuntu nomuntu. Abanye abantu bangase babe nezimpawu ezincane kakhulu, kanti abanye bangase babe nezimpawu ezinzima nezisongela ukuphila. Lezi zimpawu zivame ukuqala zingakapheli amahora ambalwa ngemva kokuthatha umuthi omusha noma ukushintsha umthamo.

Ukuze kube lula ukuqonda, ake sihlukanise lezi zimpawu zibe yizigaba ezintathu.

Yimiphi le mithi ekhulisa amazinga e-serotonin?

Lolu hlu lude kancane, kodwa kubaluleke kakhulu ukuze ukuphepha kwakho kuqaphele lokhu.

Imithi yokucindezeleka

Lena imithi evame ukuhlotshaniswa ne-serotonin syndrome. Ingozi iphezulu kakhulu uma ithathwa neminye imithi (isib. imithi ye-migraine).

• Ama-SSRI (ama-Selective serotonin reuptake inhibitors): Imithi efana ne-Fluoxetine, i-Sertraline, i-Citalopram, i-Escitalopram, ne-Paroxetine.
• Ama-SNRI (ama-Serotonin-norepinephrine reuptake inhibitors): Imithi efana ne-Venlafaxine, i-Duloxetine, i-Desvenlafaxine.
• Ama-antidepressant e-Tricyclic: Imithi efana ne-Amitriptyline, i-Nortriptyline, ne-Imipramine.
• Ama-MAOI (ama-Monoamine oxidase inhibitors): Nakuba lawa engasasetshenziswa njalo, anikezwa kwezinye izimo.

Eminye imithi

• Imithi yobuhlungu obukhulu: Iziqeda-buhlungu ezifana neTramadol, iPethidine (Meperidine), iFentanyl, kanye neMethadone.
• Umuthi Wokukhwehlela: Amanye amasiraphu okukhwehlela atholakala emakhemisi aqukethe into ebizwa ngokuthi i-Dextromethorphan . Lokhu kungathinta namazinga e-serotonin.
• Imithi ye-migraine: Imithi ye-Triptan efana ne-Sumatriptan ne-Rizatriptan.
• Imithi yokuhlanza: Imithi efana ne-Metoclopramide ne-Ondansetron.
• Amanye ama-antibiotic: I-linezolid ye-antibiotic.
• Imithi yokulawula imizwa: i-Lithium.

Ezinye izinto

• Izithasiselo zemithi: Izinto ezifana ne-St. John's wort kanye ne-Ginseng.
• Izidakamizwa ezingekho emthethweni: Izinto ezifana ne-Ecstasy (MDMA), i-LSD, i-Cocaine, ama-Amphetamine.

Ungakhathazeki ngalolu hlu. Akuwona wonke umuntu ozoba nalesi simo ngemva kokuthatha omunye wale mithi. Ingozi ivela kuphela uma usebenzisa eminye yayo ndawonye, ​​​​wandisa umthamo, noma uma umzimba wakho uzwela kuyo.

Udokotela ukubona kanjani lokhu?

Akukho ukuhlolwa kwegazi okuqondile noma ukuskenwa okuqinisekisa i-serotonin syndrome. Udokotela uzoxilonga lesi simo ngokusekelwe ezicini eziningana:

1. Izimpawu zakho: Lalela ngokucophelela lokho okuzwayo.

2. Ukuhlolwa komzimba: Ukushaya kwenhliziyo yakho, umfutho wegazi, izinga lokushisa komzimba, kanye nesimo semisipha kuzohlolwa.

3. Uhlu lwemithi oyiphuzayo: Lena yinto ebaluleke kakhulu.

Ngaphezu kwalokho, ungase futhi uhlolwe igazi nomchamo, i-X-ray yesifuba, noma i-CT scan ukuqinisekisa ukuthi awunazo ezinye izimo (isib., izifo) ezibangela izimpawu ezifanayo.

Yiziphi izindlela zokwelapha lokhu?

Ukwelashwa kuncike ebunzimeni bezimpawu zakho.

• Uma unezimpawu ezincane: Ukwelashwa okuvamile ukuyeka ukuthatha imithi ebangele izimpawu. Lokhu ngokuvamile kuzoxazulula izimpawu ngokuphelele zingakapheli amahora angama-24-72.
• Uma unezimpawu ezilinganiselwe: Uzogcinwa esibhedlela futhi uhlolwe okungenani amahora angama-24. Phakathi nalesi sikhathi, uzonikezwa i-saline (i-IV fluids) kanye nemithi efana ne-benzodiazepines yokukhathazeka.
• Uma unezimpawu ezibucayi: Lesi yisimo esiphuthumayo sezokwelapha. Uzolaliswa egunjini lokunakekelwa okujulile (i-ICU) futhi unikezwe ukwelashwa okufana nokusekelwa kobunzima bokuphefumula, ukulawula umkhuhlane ophakeme, kanye nemithi yokulawula izinga lokushaya kwenhliziyo kanye nomfutho wegazi. Ngezinye izikhathi, umuthi obizwa ngokuthi i-Cyproheptadine, ovimba ukusebenza kwe-serotonin, nawo unganikezwa.

Singazivikela kanjani kulesi simo?

Kunezinto ezimbalwa ezilula, kodwa ezibaluleke kakhulu esingazenza ukuze sihlale siphephile kulesi simo esiyingozi.

1. Zifundise ngemithi yakho: Gcina irekhodi legama, umthamo, kanye nenhloso yayo yonke imithi oyithathayo.

2. Tshela udokotela ngamunye imininingwane ephelele: Uma welashwa odokotela abaningana, qiniseka ukuthi utshela udokotela oyedwa ngemithi enikezwe abanye.

3. Ungayeki ukuthatha imithi ngaphandle kokubuza udokotela wakho: Ngisho noma uzizwa ungakhululekile, ungayeki ukuthatha imithi noma ushintshe umthamo ngaphandle kokukhuluma nodokotela.

4. Qaphela lapho uthenga umuthi ekhemisi: Uma uthenga umuthi wezinto ezifana nokukhwehlela nomkhuhlane, cela umuthi ohambisana nomuthi osuwusebenzisa kakade.

5. Naka izimpawu: Naka kakhulu noma yiziphi izinguquko emzimbeni wakho, ikakhulukazi lapho uqala umuthi omusha noma ukhulisa umthamo.