Momma yensua aduru a wɔfrɛ no Alpelisib (Vijoice) ho ade? (PIK3CA-a ɛfa onyin boro so - PROS)

Ebia wo, anaa ebia wo ba no, wo duruyɛfo aka akyerɛ wo sɛ mfi ase nnom aduru bi a wɔfrɛ no Alpelisib (ahyɛnsode: Vijoice). Sɛ wote aduru titiriw a ɛte saa din a, ɛyɛ ade a ɛfata sɛ nsɛmmisa pii bɛba w'adwenem, te sɛ "Dɛn na eyi yɛ?", "Ɛsɛ sɛ menom no dɛn?", "Dɛn ne ahwɛyiye ahorow no?" Enti mma nsuro. Ɛnnɛ, yɛbɛka aduru yi a wɔfrɛ no Alpelisib ho asɛm wɔ ɔkwan a emu da hɔ na ɛnyɛ den koraa so.

Aduru bɛn na Alpelisib yɛ?

Sɛ yɛbɛka no tiawa a, Alpelisib yɛ aduru a ɛhwɛ nkwammoaa bi a ɛwɔ nipadua no mu a enyin wɔ ɔkwan a ɛnteɛ so a wontumi nni so. Wɔde saa aduru yi di dwuma titiriw de sa tebea bi a nipadua no afã horow bi (sɛ nhwɛso no, nsa, nan, anaa ntini bi) yɛ kɛse dodo esiane awosu mu nkwaadɔm bi a wɔfrɛ no PIK3CA mu nsakrae nti . Yɛfrɛ tebea yi PIK3CA-related overgrowth spectrum (PROS) . Saa aduru yi yɛ adwuma denam sɛnkyerɛnne kwan a ɛma saa nkwammoaa nyin a ɛnteɛ no siw so, na ɛnam so di yare no so.

Ebia wo duruyɛfo bɛkyerɛw eyi ama ayaresa tebea afoforo nso, enti sɛ wowɔ nsɛmmisa bi a, wo ne wo duruyɛfo nka ho asɛm.

Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ase anom nnuru

Sɛnea ɛbɛyɛ a wubenya ahobammɔ na woanya nnuru no so mfaso kɛse no, ɛho hia sɛ woka saa nsɛm yi kyerɛ wo duruyɛfo ansa na woafi Alpelisib ase.

• Sɛ wowɔ asikreyare a: Ka kyerɛ yɛn sɛ wowɔ asikreyare dedaw anaa asikre dodow a ɛwɔ wo mogya mu a.
• Ahurututu mu nyarewa: Sɛ wowɔ ahurututu mu yare biara, te sɛ ayamtu anaa ahurututu mu yare a.
• Allergies: Hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo sɛ wowɔ allergy bi wɔ Alpelisib anaa aduru foforo biara, aduan, anaa aduru a wɔde yɛ nneɛma ho a.
• Nyinsɛn: Sɛ woanyinsɛn, worebɔ mmɔden sɛ wubenyinsɛn, anaasɛ wowɔ adwenem naayɛ ketewaa bi mpo sɛ woanyinsɛn a.
• Sɛ woyɛ ɛna a ɔma nufu a: Sɛ worema abofra nufu a.

Sɛ oduruyɛfo no nim saa nneɛma yi a, ɛbɛyɛ mmerɛw ama no sɛ ɔbɛyɛ ayaresa a ɛfata wo yiye ho nhyehyɛe.

Ɔkwan bɛn so ankasa na mede saa aduru yi di dwuma?

Ɛho hia paa sɛ wudi akwankyerɛ pɔtee a wɔde ma wɔ aduru yi a wɔde bedi dwuma ho no akyi.

• Nom aduru no sɛnea oduruyɛfo no kyerɛ no pɛpɛɛpɛ, bere koro no ara mu da biara .
• Ntwitwa anaa nwe saa tablet yi. Fa nsu mene tablet no nyinaa.
• Ɛyɛ papa sɛ wobɛnom aduru no ne adidi .
• Kɔ so nom aduru no kosi sɛ wo duruyɛfo bɛka akyerɛ wo sɛ gyae. Nnyae mpofirim, sɛ wo ho atɔ wo mpo a.

Sɛ ɛyɛ den sɛ wɔbɛmene aduru no a, dɛn na ɛsɛ sɛ woyɛ?

Ɛyɛ den ma nnipa binom, titiriw mmofra, sɛ wɔbɛmene nnuru a wɔde sa yare. Sɛ ɛba saa a, sɛnea wobɛyɛ no ni:

1. Fa tablet no gu ahwehwɛ a nsuo 2-4 ounces (bɛyɛ 60-120 ml) wom mu.

2. Bɛyɛ simma 5 akyi no, fa nsenia a ɛho tew twitwa tablet no yiye na woatutu no yiye kosi sɛ ɛbɛbɔ wɔ nsu no mu.

3. Nom saa afrafrade yi ntɛm ara.

4. Afei, fa nsu nkaribo 2-3 foforo gu ahwehwɛ koro no ara mu, hohoro aduru biara a aka wɔ ahwehwɛ no mu, na nom saa. Yɛ eyi wɔ ɔkwan bi so a aduru no mu nsu biako mpo nsɛe.

Na sɛ menom nnuru pii (a ɛboro so) nso ɛ?

Sɛ wususuw sɛ woanom aduru yi dodo a, ntwentwɛn wo nan ase. Frɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea hɔ ntɛm ara . Anaasɛ kɔ ayaresabea a ɛbɛn wo no Emergency Treatment Unit (ETU) .

Sɛ wopa nnuru dodow bi a, dɛn na ɛsɛ sɛ woyɛ?

Sɛ wo werɛ fi sɛ wobɛnom dose bi a, fa no bere a woakae ara pɛ. Nanso, sɛ ennu nnɔnhwerew 9 kosi wo dodow a edi hɔ a wode bɛma bere a wokae (i.e., bɛboro nnɔnhwerew 9 aka akyi) a, twa dodow a woayera no so. Fa dodow a edi hɔ no ara wɔ bere a wɔahyɛ da ayɛ no mu. Mfa nnuru abien prɛko pɛ da mfa nsiesie dodow a woayera no.

Nnuru afoforo a ebetumi ne saa aduru yi adi nkitaho (Drug Interactions) .

Nnuru bi a worenom betumi ne Alpelisib adi nkitaho na aka sɛnea ɛyɛ adwuma anaa nea efi mu ba. Enti, sɛ worenom nnuru a edidi so yi mu biara anaa nnuru foforo biara a wɔde ka aduan ho, vitamin, anaa nhabannuru a, ka kyerɛ wo duruyɛfo.

• Nnuru bi a wɔde sa akisikuru: Sɛ nhwɛso no, `(Carbamazepine)`, `(Phenobarbital)`, `(Phenytoin)`.
• `Cyclosporine a wɔde yɛ adwuma`
• `Eltrombopag` na ɛwɔ hɔ
• `Enzalutamide a wɔde yɛ adwuma`
• `Mitotane`
• `Rifampin` (aduru a wɔde sa nsamanwaw) .
• `Ɔhotefo. John's Wort` (nhabannuru a wɔde sa adwenemyare) .
• `Sulfasalazine a wɔde yɛ adwuma`
• `Warfarin` (aduru a wɔde ma sɛnea ɛbɛyɛ a mogya ntumi nkɔ) .

Saa nsɛm a wɔahyehyɛ yi nwiei, enti ɛbɛyɛ papa sɛ wobɛbɔ wo duruyɛfo amanneɛ wɔ nnuru a worenom nyinaa ho.

Nneɛma a ɛsɛ sɛ wohwɛ yiye wɔ ho titiriw bere a worenom aduru no

• Aduruyɛ mu nhwehwɛmu daa: Kɔ wo duruyɛfo nkyɛn daa na hwɛ sɛ wo yare no ho sɛnkyerɛnne no retu mpɔn anaasɛ ɛreyɛ kɛse anaa. Mma nntwa mogya mu nhwehwɛmu a ɛho hia (mogya adwuma) so.
• Honam ani yare a emu yɛ den: Nnipa binom betumi anya honam ani yare a emu yɛ den wɔ adapɛn kakraa bi mpo akyi bere a wɔafi aduru yi ase no.Sɛ wo ho yɛ wo hyew a, ka sɛnkyerɛnne te sɛ atiridii anaa atiridiinini ho a, ka kyerɛ wo duruyɛfo ntɛm ara. Saa akisikuru yi betumi adan kɔkɔɔ anaa kɔkɔɔ, afei akisikuru na ayɛ. Anaasɛ sɛ wuhu sɛ w’anim, w’ano, wo kɔn, anaa w’abasa mu akisikuru kɔkɔɔ ka ho a ntini a ɛho ahonhon ka ho a, frɛ wo duruyɛfo ntɛm ara.
• Atiridiinini a emu yɛ den ne nsu a ɛho ayɛ fĩ: Sɛ wo ho atɔ wo kɛse, wofe, anaasɛ wo ho fifiri dodo a, ka kyerɛ wo duruyɛfo . Nsu pii a wobɛhwere afi wo nipadua mu (nsu a ɛho ayɛ fĩ) betumi ayɛ asiane bere a worenom aduru yi no.
• Asikre a ɛwɔ mogya mu a ɛkɔ soro (Hyperglycemia): Saa aduru yi betumi ama asikre a ɛwɔ mogya mu akɔ soro. Asiane yi yɛ kɛse wɔ nnipa a wɔwɔ asikreyare dedaw mu. Sɛ wote nka sɛ sukɔm de wo sen sɛnea wotaa yɛ, wotaa tow wo ho, wote nka sɛ woabrɛ wɔ ɔkwan soronko so, anaasɛ w’ani nhu ade yiye a , ka kyerɛ wo duruyɛfo .
• Ano a ɛyɛ mmerɛw: Ebia wubenya ano a ɛyɛ mmerɛw. Nneɛma te sɛ aduru a asikre nnim a wɔwe ne nsu pii a wɔnom betumi adi eyi so. Nanso, sɛ ɔhaw no kɔ so anaasɛ emu yɛ den a, ka kyerɛ wo duruyɛfo.

Nsunsuanso bɔne a ebetumi aba esiane nnuru nti

Wobɛyɛ dɛn akora w’aduru no so yiye?

• Twe wo ho fi mmofra ne afieboa ho.
• Fa sie baabi a ɛhɔ hyew yɛ digrii Celsius 20 kosi 25 (68-77 Fahrenheit), a ɛyɛ dan mu hyew a ɛfata.
• Mfa nnuru a ne bere atwam nni dwuma.
• Sɛ woretow nnuru a wɔmfa nni dwuma anaasɛ ne bere atwam agu a, hwɛ nea wɔakyerɛw so no hwɛ sɛ ɛyɛ nea asiane biara nni ho sɛ wobɛtow agu anaa. Sɛ w’adwene mu yɛ wo naa a, bisa wo duruyɛfo. Sɛ ɛyɛ nea asiane biara nni ho sɛ wobɛtow a, yi nnuru no fi toa no mu na fa biribi te sɛ kɔfe a wɔayam, dɔte, anaa mpataa nwura fra mu, fa gu kotoku anaa ade a wɔatoto mu denneennen mu, na tow gu nwura mu.