Aduru Foforo a Wɔde Sa Adwenemhaw: Nea Ɛsɛ sɛ Wuhu Fa Auvelity Ho | Nirogi Lanka na ɔkyerɛwee

Adwenemhaw betumi ate nka sɛ sunsuma a emu yɛ duru wɔ w’asetra so, na ama biribiara ayɛ te sɛ adesoa. Sɛ wote nka sɛ wo mprempren ayaresa no mma wo ahotɔ a wuhia a, hu sɛ anidaso wɔ hɔ —nkɔso foforo a aba wɔ aduruyɛ mu no resakra adwenemhaw hwɛ ho tebea. Ɛnnɛ, yɛpɛ sɛ yɛka `Auvelity`, aduru a ɛde anidaso foforo aba nnipa pii so ho asɛm. U.S. FDA penee so wɔ afe 2022 mu, na wɔayɛ no titiriw sɛ wɔde bɛsa Adwenemhaw Kɛse (MDD).

Dɛn ne Auvelity na ɛyɛ adwuma dɛn?

Sɛ yɛbɛka no tiawa a, `Auvelity` yɛ aduru a wɔde ka bom. Ɛde nneɛma abien a tumi wom bom yɛ tablet biako: `dextromethorphan` ne `bupropion`. Fa no sɛ kuw bi a wɔbom yɛ adwuma —sɛ wɔde nnuru abien yi bom a, ayaresa no tu mpɔn sen sɛnea emu biara ankasa bɛyɛ.

• Bupropion : Eyi yɛ aduru a wonim no yiye a ekum adwenemhaw. Ɛyɛ adwuma denam `dopamine` ne `norepinephrine` dodow a ɛkɔ soro, a ɛyɛ amemene mu nnuru a ɛho hia a ɛhwɛ wo nkate so no so.
• Dextromethorphan : Ebia wubehu sɛ eyi yɛ ade a wɔtaa de yɛ ɔfe aduru mu. Nanso, wɔ saa nnuru pɔtee yi mu no, wɔahu sɛ saa ade yi nso nya amemene no akwan a ɛma obi nya adwene no so nkɛntɛnso.

Sɛ wɔka nnuru abien yi bom a , ɛma ahotɔ a eye kɛse fi adwenemhaw ho sɛnkyerɛnne ahorow mu sen `bupropion` nkutoo.

Ɔkwan bɛn so na wɔhwehwɛɛ aduru yi mu?

Ansa na aduru biara bɛkɔ ɔmanfo nkyɛn no, wɔyɛ no ayaresabea sɔhwɛ ahorow a emu yɛ den de hwɛ hu sɛ ahobammɔ ne nea etu mpɔn. Wɔnam ayaresabea nhwehwɛmu a ɛkɔ akyiri so sɔɔ `Auvelity` hwɛe. Nhwehwɛmufo de `Montgomery-Asberg Depression Rating Scale (MADRS)` susuw sɛnea adwenemhaw no mu yɛ den no. Fa eyi sɛ nsɛmmisa 10 nhwehwɛmu a ɛkɔ akyiri a ɛsɔ wo nkate a ɛfa awerɛhow, nna mu basaa, afobu, ne nkate afoforo ho hwɛ, a nkontaahyɛde fi 0 kosi 60. Nkonimdi a ɛkɔ soro kyerɛ sɛ adwenemhaw a emu yɛ den kɛse , bere a nkontaa a ɛso tew wɔ ayaresa akyi no kyerɛ sɛ wo ho bɛtɔ wo wɔ ɔkwan a ntease wom so. Saa nhwehwɛmu ahorow yi de wɔn a wɔde wɔn ho hyɛɛ mu a wɔadi mfe 18-65 a wɔwɔ Adwenemhaw Kɛse no kaa ho. Nea ɛda nsow ne sɛ, wɔayi ankorankoro a wɔwɔ adwenemyare afoforo (te sɛ `bipolar disorder` anaa `psychotic disorder`), wɔn a asiane kɛse wom sɛ wobekum wɔn ho, anaa wɔn a wɔwɔ abakɔsɛm a ɛfa akisikuru ho no anhyɛ sɔhwɛ ahorow a edi kan yi mu.

Dɛn na efii nhwehwɛmu no mu bae?

nea efii mu bae no hyɛɛ nkuran yiye. `Auvelity` daa no adi sɛ ɛyɛ adwuma yiye wɔ adwenemhaw ho sɛnkyerɛnne a wɔtew so sen placebo ne `bupropion` nyinaa, na ɛkyerɛ sɛ `MADRS` nkontabuo so tew kɛse ma wɔn a wɔde `Auvelity` di dwuma no.

So Auvelity ne nnuru afoforo di nkitaho? (Nnuru a Wɔde Di Dwuma) .

Eyi ho hia kɛse . Yiw, `Auvelity` betumi ne nnuru afoforo a ebia worenom adi nkitaho. Ɛsɛ sɛ woda nnuru no nyinaa adi kyerɛ wo duruyɛfo, a nnuru a wɔtɔn, vitamin, ne nhabannuru a wɔde ma ka ho.

Asiane a ɛwɔ Serotonin Syndrome mu

Sɛ wɔde `Auvelity` ka nnuru afoforo a ekum adwenemhaw a ɛma serotonin dodow kɔ soro a, ebetumi ama serotonin dodow a ɛyɛ hu aba amemene no mu, tebea a ɛde nkwa to asiane mu a wɔfrɛ no `Serotonin Syndrome`. Sɛ wuhu saa sɛnkyerɛnne ahorow yi a, kɔ ayaresabea ntɛm ara wɔ dwumadibea a ɛbɛn wo a wɔhwɛ ntɛmpɛ so (ER) . Bio nso, ɛsɛ sɛ nnafua 14 ahohoro bere wɔ MAOI nnuru a ekum adwenemhaw a wɔde bedi dwuma ne `Auvelity` a wofi ase no ntam.

Nneɛma Afoforo a Ɛho Hia a Ɛsɛ sɛ Wosusuw Ho

• Nnuru a ɛma dopamine kɔ soro: Esiane sɛ `Auvelity` ka dopamine dodow nti, sɛ wɔde ka nnuru afoforo a ɛte saa ara ho (sɛ nhwɛso no, Parkinson nnuru bi) a, ebetumi ama obi anya dopamine a ɛboro so, na ebetumi ama obi ayɛ basaa, ne ho popo, anaasɛ ayɛ den wɔ kankyee mu .
• Nsã: Ɛsɛ sɛ wokwati koraa anaasɛ woto nsa a wobɛnom ano hye katee bere a worenom `Auvelity`, efisɛ nea wɔaka abom no ma asiane a ɛwɔ hɔ sɛ wobɛhaw wo ho no yɛ kɛse .
• Koma mu nnuru: Nnuru te sɛ `digoxin` betumi anya ne nkɛntɛnso asesa denam `Auvelity` so. Yɛsrɛ sɛ hwɛ hu sɛ wo duruyɛfo no nim ayaresa a ɛfa koma ho nyinaa.
• Mmerɛbo mu nneɛma a ɛsakra: Wo mmerɛbo no na ɛbubu nnuru a wɔde enzymes te sɛ `cytochrome P450 (CYP450)` di dwuma. `Auvelity` betumi aka saa nhyehyɛe yi, a ebetumi asakra sɛnea wo nnuru afoforo yɛ adwuma wɔ wo nipadua mu.

Ɔkwan bɛn so na wɔnom saa aduru yi na dɛn ne nea efi mu ba?

`Auvelity` yɛ nea wobetumi anya denam nnuru a wɔkyerɛw ma nkutoo so. Mpɛn pii no, dodow a wɔtaa de ma no fi ase de aduru biako da biara da wɔ nnansa a edi kan no mu, na wɔde aduru biako di akyi mprenu da biara (a ɛda ntam nnɔnhwerew 8 ntam).

Nneɛma bɔne a ebetumi afi mu aba ne nea wɔhwɛ so

• Mogya Nhyɛso a Ɛkɔ Anim: Ebia wo duruyɛfo betu wo fo sɛ hwɛ wo mogya so daa bere a worenom aduru yi no.
• Adwene a ɛyɛ basaa:Saa aduru yi betumi ama obi adwene atu afra. Yɛsrɛ sɛ fa ahwɛyiye bere a woreka kar, wode mfiri redi dwuma, anaa woreyɛ nnwuma wɔ baabi a asiane wɔ hɔ sɛ wobɛhwe ase no.
• Aniwa mu Nkɛntɛnso: Sɛ w’ani yɛ wo yaw, wo ho yɛ kɔkɔɔ, anaa nsakrae biara ba w’ani so a, kɔ wo duruyɛfo nkyɛn.
• Suban mu Nsakrae: Ankorankoro binom betumi anya adwene mu naayɛ, adwenem naayɛ (nneɛma a enni hɔ a wobehu anaa wɔbɛte), anaasɛ ɛbɛyɛ den sɛ wobehu nokwasɛm.
• Akisikuru: Sɛ wɔde saa aduru yi ka nsa ho a, asiane a ɛwɔ hɔ sɛ obi benya akisikuru no yɛ kɛse. Sɛ wo ho tɔ wo bere a worenom aduru yi a, gyae nom ntɛm ara na kɔ wo duruyɛfo nkyɛn.
• Nyinsɛn ne Nufu a Wɔma: Saa aduru yi nyɛ nea asiane biara nni ho wɔ nyinsɛn mu anaa bere a wɔrema nufu no. Sɛ woreyɛ nhyehyɛe anyinsɛn, woanyinsɛn dedaw, anaa worenom nufu a, ka kyerɛ wo duruyɛfo ntɛm ara.

Afotu a Ɛho Hia a Ɛfa Adwene a Ɛfa Nnipa a Wokum Wɔn Ho Ho

Te sɛ nnuru afoforo bi a ekum adwenemhaw no, `Auvelity` betumi ama asiane a ɛwɔ hɔ sɛ wobekum wɔn ho adwene anaa nneyɛe wɔ nnipa binom mu no akɔ soro kakra , titiriw wɔ ayaresa no mfiase. Wɔtaa hu eyi wɔ ankorankoro nkumaa mu. Sɛ wo anaa w’abusua muni bi nya nsusuwii a ɛte saa a, mma wo nkutoo ntra hɔ.

• Frɛ ntɛmpɛ adwumayɛbea (911) anaa wo mpɔtam hɔ ahokyere hotline ntɛm ara.
• Sɛnea ɛbɛyɛ a, kɔ ayaresabea dwumadibea a ɛhwɛ ntɛmpɛ so a ɛbɛn wo no.
• Bɔ wo duruyɛfo amanneɛ ntɛm ara wɔ saa nsɛm a ɛhaw wo yi ho.

Eyi nyɛ biribi a ɛsɛ sɛ wɔde sie. Mmoa a wobɛhwehwɛ ntɛm no ho hia yiye. Auvelity, adwenemhaw, adwenemyare, aduru a ekum adwenemhaw, dextromethorphan, bupropion, serotonin syndrome, adwenemhaw aduru, nea efi mu ba