So woafe nna kakraa bi ni? Ebia wɔde ahurututu kakra bɛka ho? Yɛtaa susuw eyinom sɛ atiridii ho sɛnkyerɛnne. Nanso ɛtɔ mmere bi a, ebia biribi foforo bi wɔ sɛnkyerɛnne nketenkete yi akyi a ɛsɛ sɛ yɛhwɛ so. Ɛnnɛ yɛrebɛka ahurututu mu yareɛ bi a nnipa pii ntee ho asɛm, nanso ɛho hia sɛ wɔhunu ho asɛm. Ɛno ne Ahurututu mu Kokoram Akisikuru. Nsuro bere a wote saa din yi ne asɛmfua "tumor" no. Momma yɛnte eyi ase pɛpɛɛpɛ.
Dɛn ne Ahurututu mu Kokoram Akisikuru?
Sɛ yɛbɛka no tiawa a, eyi yɛ kokoram akisikuru bi a ɛba ahurututu mu. Nanso ɛnyɛ basabasa anaasɛ ɛtrɛw ntɛmntɛm sɛnea ebia yebesusuw bere a yɛte asɛmfua "kokoram" no. Saa akisikuru yi fi nkwammoaa soronko bi a ɛwɔ yɛn ahurututu mu a wɔfrɛ no ``Neuroendocrine cells.''
Fa no sɛ saa ``Neuroendocrine`` nkwammoaa yi yɛ abɔfo nketewa wɔ yɛn nipadua mu. Wotumi nya nkrasɛm te sɛ ntini mu nkwammoaa, na te sɛ endocrine nkwammoaa no, wɔyɛ hormone ahorow a egyina saa nkrasɛm no so de di dwumadi ahorow a ɛwɔ nipadua no mu so. Wɔ ahurututu no mu no, saa nkwammoaa yi boa ma yɛhwɛ nneɛma te sɛ mframa dodow a yɛhome ne mogya a ɛsen so.
Enti, biribi nti, sɛ nkwammoaa yi fi ase kyekyɛ a wontumi nni so a, akisikuru bi ba wɔ hɔ. Eyi ne nea yɛfrɛ no `(Carcinoid Tumor)`. Saa akisikuru yi nso tumi ba wɔ nipadua no mu mmeae te sɛ aduan mu ntini ne asaabo. Nanso wɔn mu bɛyɛ nkyem abiɛsa mu biako na ɛba ahurututu no mu.
Saa nnuaba yi ahorow atitiriw abien na ɛwɔ hɔ.
Eyi ho hia yiye sɛ yehu, efisɛ ɛsono sɛnea wɔsa yare no ne ne su a egyina ne su so.
1. Carcinoid Tumors a ɛtaa ba
Eyi ne ɔkwan a ɛtaa ba . Ɛyɛ ahurututu mu kokoram akisikuru a wɔahu no mu 90%. Nea eye sen biara ne sɛ saa akisikuru yi nyin brɛoo paa na ɛntaa nkɔ nipadua no afã afoforo. Enti, mpɛn pii no, wotumi sa wɔn yare yiye.
2. Carcinoid Tumors a Ɛnyɛ Nea Wɔtaa Yɛ
Saa ɔkwan yi ntaa mma. Ebetumi anyin ntɛmntɛm kakra asen nea wɔtaa nyin no. Ɛda adi sɛ ɛbɛtrɛw akɔ nipadua no afã afoforo nso. Wɔahu nso sɛ asiane a ɛwɔ hɔ sɛ wobenya saa ``(Atypical)`` yi dɔɔso wɔ sigaretnomfo mu.
Nea ɛho hia ne sɛ, ɛmfa ho sɛnea ɛte biara no, eyinom yɛ soronko koraa wɔ ahurututu mu kokoram a ɛba daa no ho na wɔyɛ wɔn ade yiye wɔ ayaresa mu.
Dɛn ne eyi ho sɛnkyerɛnne?
Mpɛn pii no, titiriw wɔn a wɔwɔ ``Typical'' cysts , nnipa pii nhu sɛnkyerɛnne biara.Wɔtaa hu eyinom wɔ akwanhyia mu bere a wɔreyɛ wɔn koko X-ray esiane biribi foforo nti. Nanso, nnipa binom betumi anya yare no ho sɛnkyerɛnne a edidi so yi:
Mede saa su ahorow yi bɛkyerɛ wɔ pon so sɛnea ɛbɛyɛ a ɛbɛyɛ mmerɛw sɛ wɔbɛte ase.
| Su ahorow a ɛwɔ hɔ | Nkyerɛmu |
|---|---|
| Nsɛnkyerɛnne a ɛtaa ba a ɛfa ahurututu ho | |
| Ɛwa | Ɔfe a ɛtaa ba, ɛtɔ mmere bi a, ɛyɛ nwini anaa mogya kakra. |
| Koko mu yaw | Ɛyaw, titiriw bere a worehome denneennen no. |
| Ɔhome a ɛyɛ den (dyspnea) . | Wɔte ɛyaw no nka bere a wɔreyɛ adwuma a ɛnyɛ den mpo no. |
| Nnyigyei a ɛyɛ abɛn bere a wɔrehome | Ahomegye yɛ nnyigyei a wɔte bere a wɔrehome, na ɛte sɛ ayamtufo de. |
| Nsɛnkyerɛnne a ɛbata Carcinoid Syndrome ho | |
| Ɔhohoro a emu yɛ den | Tebea a nkwaadɔm te sɛ serotonin a akisikuru no de ba. |
| Anim ne kɔn a ɛyɛ kɔkɔɔ | Anim ne kɔn no fã a ɛyɛ kɔkɔɔ mpofirim na ɛyɛ kɔkɔɔ. |
| Mu duru a ɛkɔ soro a ntease nnim | Ebia eyi fi nkɛntɛnso a hormone ahorow de ba no. |
Saa nsɛnkyerɛnne yi a wɔfrɛ no `Carcinoid Syndrome` no ba efisɛ akisikuru no yɛ hormone pii sen sɛnea nipadua no hia na ɛde ka mogya no ho. Nanso, wɔntaa nhu eyi nso.
Dɛn nti na saa akisikuru yi ba? Dɛn ne nneɛma a ɛde asiane ba?
Nyansahufo da so ara nnim nea enti a saa "neuroendocrine" nkwammoaa yi fi ase kyekyɛ mpofirim a wontumi nni so no ankasa , nanso wɔahu sɛ nnipa binom wɔ asiane kɛse mu kakra sɛ wobenya tebea no.
- Awosu mu nneɛma a ɛde ba: Awosu mu tebea bi wɔ hɔ a ɛntaa nsi, a wonya fi awo mu a wɔfrɛ no ``Multiple Endocrine Neoplasia type 1 (MEN1).`` Nnipa a wɔwɔ saa tebea yi wɔ asiane kɛse mu sɛ wobenya carcinoid tumors.
- Sigaretnom: Sigaretnom betumi aboa ma akisikuru aba, titiriw ``atypical`` tumors.
- Bɔbeasu: Mmea wɔ asiane kɛse mu kakra sɛ wobenya saa tebea yi.
- Mfe a wɔadi: Ɛwom sɛ ɛtaa ba nnipa a wɔadi fi mfe 45 kosi 55 mu de, nanso tebea yi betumi aba obiara a wadi mfe biara mu, mmofra nkumaa mpo.
Ɔkwan bɛn so na wobetumi ahu yare no?
Okay, ma yɛnka sɛ wowɔ saa sɛnkyerɛnne ahorow yi. Sɛ wokɔ oduruyɛfo nkyɛn a, obedi kan abisa wo wo yare no ho sɛnkyerɛnne, afei ɔde afiri a wɔde tie asɛm ahwɛ w’ahurututu mu. Afei ebia ɔbɛhyɛ sɛ wɔnyɛ nhwehwɛmu pii mfa nkyerɛ sɛ wɔahu yare no.
1. Mfoninitwa: Ade a edi kan a wɔyɛ ne koko so X-ray . Eyi betumi aboa ma wɔahu sɛ ebia biribi a ɛnteɛ wɔ ahurututu no mu anaa. Wobetumi ayɛ CT scan (Computed Tomography scan) na ama wɔahu akisikuru no kɛse ne beae a ɛwɔ no pefee.
2. Mogya ne nsu mu nhwehwɛmu: Saa nhwehwɛmu yi boa ma wohu sɛ ebia nkwaadɔm bi a saa akisikuru yi yɛ no wɔ mogya anaa nsu mu anaa.
3. Biopsy: Eyi ne sɔhwɛ a ɛho hia sen biara a wɔde si yare no so dua 100%. Nea wɔyɛ wɔ ha ne sɛ wobegye ntini ketewaa bi afi akisikuru no mu na wɔde afiri a wɔde hwɛ nneɛma nketenkete ahwɛ mu. Eyi nso betumi akyerɛ pɛpɛɛpɛ sɛ ebia akisikuru no yɛ ``Typical`` anaa ``Atypical``. Ɔkwan a wɔtaa fa so nya saa ntini yi ne ahurututu mu nhwehwɛmu . Ɛha yi, wɔde afiri a ɛyɛ tratraa a ɛyɛ mmerɛw a mfoninitwa afiri abata ho no fa ano anaa hwene mu kɔ ahurututu no mframa kwan mu na wonya akisikuru no fã bi.
Ɔkwan bɛn so na wɔsa?
Wo ayaresa nhyehyɛe no begyina akisikuru no ko, ne kɛse, beae a ɛwɔ, ne w’akwahosan nyinaa so. Mpɛn pii no, wobetumi asa saa akisikuru yi koraa .
Sɛɛgyiri
Ayaresa titiriw a edi mu sen biara a wɔde sa eyi ne oprehyɛn a wɔde yi akisikuru no fi hɔ.
- Wedge Resection: Woyi akisikuru no ne ahurututu no fã ketewaa bi a atwa ho ahyia no nkutoo fi hɔ.
- Lobectomy: Woyi ahurututu bi fã bi, anaa ɔfã kɛse bi fi hɔ.
- Pneumonectomy: Ɛntaa mma koraa, sɛ ɛho hia a, woyi ahurututu mũ no nyinaa.
Bere a wɔreyɛ oprehyɛn no, woyi ntini pii a ɛbɛn akisikuru no nso na wɔhwehwɛ mu hwɛ sɛ kokoram nkwammoaa atrɛw akɔ mu anaa.
Ayaresa afoforo
Sɛ wontumi nyi akisikuru no mfi hɔ koraa, anaasɛ atrɛw akɔ mmeae afoforo a, ebia ayaresa afoforo ho behia.
- Radiation Therapy: Wɔde mframa a ahoɔden kɛse wom sɛe kokoram nkwammoaa.
- Nnuru a wɔde sa yareɛ: Wɔde nnuru te sɛ `(Octreotide)` di dwuma de siw `Carcinoid Syndrome` ho sɛnkyerɛnne ano, na wɔde nnuru te sɛ `(mTOR inhibitors)` di dwuma de siw akisikuru no nyin ano.
- Nnuru a wɔde sa yare: Esiane sɛ saa akisikuru yi taa nyin nkakrankakra nti, wɔmfa nnuru a ekum nkwammoaa a ɛpaapae ntɛmntɛm no nni dwuma. Nanso, ɛtɔ mmere bi a ebetumi ayɛ nea ɛho hia ma akisikuru a enyin ntɛmntɛm a ɛyɛ ``atypical'' type.
So wobetumi asa yare yi koraa?
Eyi yɛ asɛmmisa a nnipa pii wɔ. Nnuruyɛfo twentwɛn wɔn nan ase kakra sɛ wɔde asɛmfua "wɔasa no koraa" bedi dwuma bere a wɔreka kokoram ho asɛm no, efisɛ hokwan ketewaa bi wɔ hɔ bere nyinaa sɛ ɛbɛsan aba.
Nanso, carcinoid akisikuru a ɛtaa ba no yɛ nea wotumi sa yiye na wotumi sa . Asiane a ɛwɔ hɔ sɛ ɛbɛsan aba bio wɔ ayaresa akyi no nnu 4%. Ɛno kyerɛ sɛ nnipa 100 biara mu 96 rennya ɔyare no bio.
Akisikuru a ɛnyɛ nea wɔtaa yɛ no a wɔbɛsa no yɛ den kakra. Ebia wobehia ayaresa ahorow a wɔaka abom. Sɛ yɛka ne nyinaa bom a, nnipa a wɔahu sɛ wɔwɔ saa yareɛ yi mu 89% (a ahodoɔ mmienu no nyinaa ka ho) da so ara wɔ akwahosan pa wɔ mfeɛ 5 akyi. Eyi yɛ nea efi mu ba pa ara ma kokoram bi.
Bere bɛn na ɛsɛ sɛ wohwehwɛ aduruyɛ mu afotu? Bere bɛn na ɛsɛ sɛ wokɔ ETU?
Ade a ɛho hia sen biara ne sɛ wobɛma w’ani aku wo nipadua ho. Ɛho hia sɛ yɛyɛ ade ntɛm wɔ tebea horow a edidi so yi mu.
| Akwannya | Nea ɛsɛ sɛ wɔyɛ |
|---|---|
| Hwɛ wo duruyɛfo. | |
Sɛ wowɔ sɛnkyerɛnne foforo anaasɛ ɛreyɛ kɛse a:
| |
| Kɔ Emergency Treatment Unit (ETU) ntɛm ara. | |
Sɛ wowɔ saa sɛnkyerɛnne ahorow a emu yɛ den yi a:
| |
Nkrasɛm a Wɔde Kɔ Fie
- Ahurututu mu kokoram yɛ kokoram a ɛntaa nsi a ɛba ahurututu mu. Nanso ɛsono wɔn koraa wɔ ahurututu mu kokoram a ɛba daa no ho.
- Ɔkwan a ɛtaa ba (a ɛtaa ba) no nyin brɛoo paa na ɛkame ayɛ sɛ wobetumi asa koraa denam ayaresa so .
- Nnipa pii nhu sɛnkyerɛnne biara , enti mmu w’ani ngu nneɛma te sɛ ɔfe a ɛkɔ so daa anaasɛ akisikuru so.
- Ayaresa titiriw ne oprehyɛn a wɔde yi akisikuru no fi hɔ .
- Sɛ wusuro anaa w’adwene mu yɛ wo naa wɔ yare yi ho a, ade a eye sen biara a ɛsɛ sɛ woyɛ ne sɛ wo ne wo duruyɛfo bɛkasa pefee . Ɔbɛma wo nsɛm ne akwankyerɛ a wuhia nyinaa.
- Sɛ wonom sigaret a, gyae a wubegyae no ne ɔkwan a eye sen biara a wobɛfa so abɔ wo ho ban afi nyarewa pii a efi ahurututu mu ho.
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