So woate nka pɛn sɛ w’ani fitaa no ayɛ kɔkɔɔ kakra? Anaasɛ sɛ wo honam ani yɛ kɔkɔɔ kakra? Ebia ɛda adi kɛse bere a wowɔ atiridiinini, bere a woayɛ basaa wɔ sɔhwɛ bi ho, anaa bere a wunnii aduan a ɛdɔɔso no. Nnipa pii ho popo ntɛm ara bere a wohu eyi no, na wosusuw sɛ, "Oo, so me mmerɛbo yare ankasa?" Nanso ɛnyɛ bere nyinaa na eyi yɛ aniberesɛm. Ɛnnɛ yɛreka Gilbert Syndrome, tebea a ɛtaa ba yiye a ɛda saa sɛnkyerɛnne ahorow yi adi, nanso mpɛn pii no ɛnyɛ asiane ho asɛm.
Sɛ yɛbɛka no tiawa a, dɛn ne Gilbert Yare no?
Gilbert yare no yɛ awosu mu yare bi a ɛka yɛn mmerɛbo. Ɛyɛ nsakrae ketewaa bi a ɛba sɛnea yɛn nipadua yɛ adwuma mu sen yare a emu yɛ den. Ɛba bere a yɛn nipadua no ntumi nyɛ ade bi a wɔfrɛ no bilirubin ho adwuma yiye no.
Afei ebia woresusuw nea ɛyɛ bilirubin yi ho. Susuw ho hwɛ, mogya mu nkwammoaa kɔkɔɔ a ɛwɔ yɛn nipadua mu no nso wɔ nkwa nna pɔtee bi. Sɛ mogya mu nkwammoaa kɔkɔɔ dedaw yi sɛe a, wɔyɛ ade kɔkɔɔ bi sɛ ade a ɛka ho. Ɛno ne nea yɛfrɛ no bilirubin .
Mpɛn pii no, wɔ obi a ɔwɔ apɔwmuden mu no, wogye bilirubin yi fi mmerɛbo mu, de ka bile ho, na woyi fi nipadua no mu. Ɛte sɛ yɛn nipadua no ‘nwura a wɔde di dwuma ho nhyehyɛe’ no. Nanso, wɔ obi a ɔwɔ Gilbert yare no mu no, mmerɛbo no ntumi nyɛ enzyme a ɛyɛ adwuma yi a ɛdɔɔso. Nea enti a ɛte saa ne sɛ nsakrae ketewaa bi ba awosu mu abɔde (`UGT1A1` awosu mu abɔde) bi a ɛkyerɛ nipadua no sɛ ɛnyɛ saa enzyme no mu. Ne saa nti, bilirubin bi boaboa ano wɔ mogya no mu, na wontumi nyi mfi nipadua no mu koraa. Wɔfrɛ bilirubin dodow a ɛkɔ soro yi wɔ mogya mu yi wɔ aduruyɛ mu sɛ hyperbilirubinemia . Bilirubin a ɛboro so a ɛboaboa ano wɔ mogya no mu no ma aniwa ne honam ani yɛ kɔkɔɔ.
Nea ɛho hia ne sɛ Gilbert yare no nyɛ yare a ɛsɛe mmerɛbo no anaa ɛma egyae adwumayɛ. Ɛyɛ nsakrae ketewaa bi a asiane biara nni ho wɔ mmerɛbo dwumadi mu ara kwa.
So tebea yi abu so wɔ ɔmanfo mu?
Aane. Ɛwom sɛ nnipa pii ntee ho asɛm da de, nanso Gilbert yare no yɛ tebea a abu so sen sɛnea ebia wubesusuw. Amanneɛbɔ ahorow bi kyerɛ no, nnipa 100 biara mu 3 kosi 7 betumi anya saa yare yi wɔ wiase nyinaa. Ɛno kyerɛ sɛ ebia nnipa pii a wɔatwa wo ho ahyia no wɔ bi. Mpɛn pii no, saa nkurɔfo yi nnim mpo.
Mpɛn pii no, saa tebea yi abu so wɔ mmarima mu sen mmea. Ebetumi aka nnipa a wɔadi mfe ne abusuakuw biara.
Dɛn ne Gilbert yare no ho sɛnkyerɛnne?
Ade a ɛyɛ nwonwa wɔ ha ne sɛ bɛyɛ nnipa baasa biara a wɔwɔ Gilbert yare no mu biako nkyerɛ yare no ho sɛnkyerɛnne biara. Wohu ho asɛm bere a oduruyɛfo bi ka sɛ wɔn bilirubin dodow kɔ soro kakra bere a wɔyɛ wɔn mogya mu nhwehwɛmu esiane biribi foforo nti no nkutoo.
Nsɛnkyerɛnne titiriw a wɔtaa hu wɔ wɔn a wɔda sɛnkyerɛnne ahorow adi no mu ne jaundice . Ɛyɛ,
- Aniwa fitaa a ɛyɛ kɔkɔɔ.
- Wora a ɛyɛ kɔkɔɔ.
Saa kɔla kɔkɔɔ yi taa tra nna kakraa bi pɛ. Ɛba na ɛkɔ. Ɛnsɛe nipadua no. Ɛwom sɛ ebia ɛbɛyɛ nea ɛnyɛ dɛ kakra efisɛ ɛsakra sɛnea ɛte no kakra de, nanso ɛnyɛ akwahosan ho asiane.
Ɛntaa mma sɛ nnipa binom benya ɔhaw nketenkete afoforo de aka sɛnkyerɛnne titiriw yi ho. Wɔabobɔ eyinom din wɔ pon a ɛwɔ ase ha no mu.
| Nsɛnkyerɛnne afoforo a ebia ɛntaa mma | Nkyerɛkyerɛmu a ɛnyɛ den |
|---|---|
| Nsu a ɛyɛ tumm anaa nsu a ɛyɛ dɔte kɔla | Ebia nsu kɔla bɛsakra bere a bilirubin dodow kɔ soro no. |
| Ɔbrɛ | Ɔbrɛ a wɔte nka bere nyinaa a ntease pɔtee biara nni ho. |
| Nnuan a wɔyam no mu haw ahorow | Yafunu mu yaw, akisikuru, akisikuru, ne nea ɛkeka ho. |
| Ɛyɛ den sɛ wobedu apam bi ho | Sɛ́ wobɛte nka sɛ ɛyɛ den sɛ wode w’adwene besi biribi so. |
| Tiyɛ ne adwenemhaw | Ebia nnipa binom nso bɛbɔ amanneɛ sɛ wɔanya yare no ho sɛnkyerɛnne te sɛ eyinom. |
Dɛn ne nneɛma a ɛma aniwa no yɛ kɔkɔɔ kɛse?
Ɛnyɛ bere nyinaa na obi a ɔwɔ Gilbert yare no nya bilirubin dodow a ɛkɔ soro. Nneɛma bi betumi ama saa dodow yi akɔ soro bere tiaa bi, na ama aniwa ne honam ani ada adi kɛse (jaundice). Wɔfrɛ eyinom sɛ ‘triggers’. Sɛ wowɔ saa tebea yi a, ɛho hia sɛ wuhu saa nneɛma yi.
| Nkanyan | Ɔkwan bɛn so na eyi ma bilirubin kɔ soro? |
|---|---|
| Nsu a ɛho ntew | Sɛ woannom nsu a ɛdɔɔso awia a, bilirubin dodow a ɛwɔ mogya no mu no kɔ soro. |
| Mmuadadi anaa aduan a wohuruw | Sɛ wokɔ bere tenten a wunnnidi a, wo nipadua no fa akwan foforo so nya ahoɔden. Wɔ saa adeyɛ yi mu no, bilirubin dodow kɔ soro. |
| Nyarewa ne ɔyare mmoawa | Yare biara te sɛ atiridii anaa atiridiinini de adwennwen ba nipadua no so. Saa adwennwen yi betumi ama mmerɛbo no bilirubin a ɛyɛ adwuma no ayɛ brɛoo. |
| Ɔbrɛ | Adwennwen a nneɛma te sɛ sɔhwɛ, adwuma mu haw, ne ankorankoro nsɛm de ba nso betumi aka nipadua no mu nkwaadɔm na ama bilirubin dodow akɔ soro. |
| Ahoɔden a wɔbɔ boro so | Apɔw-mu-teɛteɛ a ɛboro so ne apɔw-mu-teɛteɛ boro so nso betumi ama bilirubin dodow akɔ soro bere tiaa bi. |
| Brayɛbea a ɛba mmea mu | Bilirubin dodow nso betumi akɔ soro wɔ mmea binom mu esiane nsakrae a ɛba wɔ hormone mu bere a wɔrekɔ brayɛ mu nti. |
Ɔkwan bɛn so na oduruyɛfo hu saa tebea yi?
Ɛwom sɛ Gilbert yare no yɛ yare a wɔde awo obi de, nanso wɔtaa hu no wɔ mmerantebere ne mmabaabere anaa mpanyin afe so. Nea enti a ɛte saa ne sɛ nkwaadɔm mu nsakrae a ɛba bere a obi anyin no betumi ama bilirubin a wɔyɛ no akɔ soro, na ɛno betumi ama yare no ho sɛnkyerɛnne ada adi nea edi kan.
Mpɛn pii no, wohu eyi ara kwa. Sɛ wɔyɛ mogya mu nhwehwɛmu esiane biribi foforo nti a, oduruyɛfo no hu sɛ bilirubin dodow no kɔ soro kakra sen sɛnea ɛte daa.
Afei, wɔyɛ nhwehwɛmu pii bio de hu sɛ ebia biribi foforo bi a anibere wom de bilirubin dodow a ɛkɔ soro yi ba anaa (e.g., mmerɛbo mu yare te sɛ mmerɛbo mu yare).
- Mmɛn Dwumadi Ho Nhwehwɛmu: Eyinom betumi ama yɛanya mmerɛbo no akwahosan ho adwene pa. Wɔ Gilbert yare no mu no, biribiara taa yɛ nea ɛfata gye bilirubin nkutoo.
- Awosu mu Nhwehwɛmu: Wɔ tebea horow bi mu no, sɛ ɛho hia sɛ wɔde si so dua sɛ wɔahu yare no a, wobetumi ayɛ awosu mu nhwehwɛmu de ahwɛ sɛ nsakrae bi aba `UGT1A1` awosu mu nkwaadɔm no mu anaa. Nanso, ɛnyɛ bere nyinaa na eyi ho hia.
Sɛ nhwehwɛmu afoforo nyinaa yɛ nea ɛfata na wunni sɛnkyerɛnne foforo biara a emu yɛ den a, oduruyɛfo no bɛka sɛ wowɔ Gilbert yare no.
So tebea yi hwehwɛ sɛ wɔsa yare? So nkɛntɛnso bi wɔ hɔ a ɛtra hɔ kyɛ?
Ade a ɛho hia sen biara a ɛsɛ sɛ wuhu ni:
Gilbert yare no yɛ tebea a asiane biara nni ho a enhia sɛ wɔsa.
Yiw, wotee no yiye. Eyi nhia nnuru anaa ayaresa titiriw biara. Efisɛ ɛnsɛe wo mmerɛbo anaa wo nipadua mu akwaa foforo biara bere tenten. Obi a ɔwɔ Gilbert yare no betumi atra ase apɔwmuden koraa, nkwa tenten, te sɛ obi a onni saa tebea yi ara pɛ.
Ɛwom sɛ aniwa kɔkɔɔ betumi ayɛ nea ɛnyɛ dɛ kakra sɛ wobɛhwɛ de, nanso ɛnyɛ akwahosan ho asiane biara. Sɛ wokwati nneɛma a ɛkanyan adwene a yɛaka ho asɛm wɔ atifi hɔ no a, wubetumi adi aniwa kɔkɔɔ a ɛtaa ba no so.
Enti bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn?
Ɛwom sɛ Gilbert yare no nyɛ asiane biara de, nanso aniwa a ɛyɛ kɔkɔɔ (jaundice) ho sɛnkyerɛnne no nso betumi ayɛ mmerɛbo mu nyarewa afoforo a emu yɛ den ho sɛnkyerɛnne. Enti,Sɛ wuhu sɛ aniwa no ayɛ kɔkɔɔ nea edi kan anaasɛ wowɔ sɛnkyerɛnne ahorow a edidi so yi mu biara a, ɛho hia sɛ wohwehwɛ aduruyɛfo afotu. Eyi bɛboa ma woahu sɛ ebia wowɔ Gilbert yare anaa tebea foforo bi.
Bere a ɛsɛ sɛ wokɔ wo duruyɛfo nkyɛn:
- Sɛ wo honam ani anaa w’ani yɛ kɔkɔɔ a ɛda adi (jaundice).
- Sɛ wotaa yɛ wo yafunu mu yaw anaasɛ wo ho yɛ wo yaw a.
- Sɛ nipadua no te nka sɛ wabrɛ kɛse a.
- Sɛ nsuo no kɔla yɛ bruu tuntum/cola a.
- Sɛ wowɔ sɛnkyerɛnne te sɛ atiridiinini ne atiridiinini a.
Ɛnsɛ sɛ wobu ani gu saa sɛnkyerɛnne ahorow yi so efisɛ ebetumi ayɛ nyarewa afoforo ho sɛnkyerɛnne. Wo duruyɛfo bɛyɛ nhwehwɛmu a ɛho hia na wama wo afotu a ɛfata sen biara.
Nkrasɛm a Wɔde Kɔ Fie
- Gilbert Syndrome nyɛ yare a ɛsɛ sɛ wosuro. Ɛyɛ tebea a abu so yiye, a asiane biara nni ho a ɛkɔ so wɔ mmusua mu.
- Nea enti a ɛte saa ne sɛ mmerɛbo no ntumi nyɛ ade bi a wɔfrɛ no bilirubin ho adwuma wɔ ɔkwan a ɛfata so.
- Nsɛnkyerɛnne titiriw ne aniwa ne honam ani yɛ kɔkɔɔ (jaundice). Eyi ba na ɛkɔ. Na ɛnsɛe nipadua no.
- Saa kɔla kɔkɔɔ yi betumi akɔ soro bere tiaa bi esiane nneɛma te sɛ adwennwen, yare, ne aduan a wohuruw nti.
- Saa tebea yi nhia ayaresa biara. Wubetumi abɔ bra a ahoɔden wom koraa.
- Sɛ worehu aniwa kɔkɔɔ nea edi kan anaasɛ wowɔ sɛnkyerɛnne afoforo a ɛyɛ soronko a, hwɛ hu sɛ wobɛkɔ wo duruyɛfo nkyɛn ma wahu yare no pɛpɛɛpɛ.
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