So wo nsateaa ne wo nan ase ayɛ kɔkɔɔ na ɛho ayɛ hyew? Ebetumi ayɛ Hand-Foot Syndrome''!

Sɛ woreyɛ nnuru a wɔde sa kokoram, anaasɛ wunim obi a ɔreyɛ saa a, ɛtɔ mmere bi a wubetumi anya nsakrae kakra, wo nsateaa ne wo nan ase ayɛ kɔkɔɔ, wo ho ahonhon, anaasɛ wobɛte yaw. Wɔ ebinom fam no, eyi betumi ayɛ osuahu a ɛhaw adwene kakra. Mma ɛnhaw wo, eyi yɛ ade a ɛtaa ba. Ɛnnɛ yɛrebɛka saa tebea yi a wɔfrɛ no ``Hand-Foot Syndrome - HFS'' , anaa sɛnea nnuruyɛfo frɛ no ``Palmar-Plantar Erythrodysesthesia'' ho asɛm.

Dɛn ne ``Nsa-Nan Ho Yare''? Momma yɛnte ase kɛkɛ!

Sɛ yɛbɛka no tiawa a, ``Hand-Foot Syndrome'' yɛ honam ani adeyɛ a nnuru bi a wɔde ``chemotherapy'' yɛ na ɛde ba. Ne titiriw no, wo nsateaa ne wo nan ase betumi ayɛ kɔkɔɔ, ahonhon, na ɛtɔ mmere bi a ɛbɛyɛ yaw. Eyi yɛ ɔhaw a ɛtaa ba wɔ kokoram ayaresa mu. Enti ɛho hia sɛ wohu eyi.

Nnuru ahorow bɛn na wɔde sa Hand-Foot Syndrome?

Ɛnyɛ nnuru a wɔde sa yare nyinaa na ɛde tebea yi ba. Nanso, nnuru bi wɔ hɔ a wɔahu sɛ ɛda adi sɛ ɛde ba. Wodii kan huu saa "Hand-Foot Syndrome" yi bere a wɔmaa mogya mu kokoram ayarefo aduru "cytarabine" dodow a ɛkɔ soro no.

Nnuru ahorow a wɔtaa de sa yare a ɛde HFS ba ne:

• `(Kapecitabine)`
• `(Docetaxel)`
• `(Doxorubicin a wɔde liposomal ayɛ a wɔde pegylated ayɛ - PLD)`
• `(5-fluorouracil)`

Nnuru a wɔde sa yare afoforo wɔ hɔ a ebetumi de HFS aba, ɛwom sɛ ɛyɛ kakraa bi de:

• `(Bleomycin)`
• `(Cisplatin)`
• `(Saiklophosphamide)`
• `(Daunorubicin)`
• `(Doxifluridine)`
• `(Etoposide)`
• `(Fludarabine)`
• `(Gemcitabine)`
• `(Nsuo mu nsuo a ɛwɔ nsuo mu)`
• `(Idarubicin)`
• `(Ixabepilone)`
• `(Methotrexate)`
• `(Mitotane)`
• `(Paclitaxel)`
• `(Tegafur)`
• `(Thiotepa)`
• `(Vinorelbine)`

Sɛ worenom saa nnuru yi mu biara a, ɛyɛ papa sɛ wobɛhwɛ yie kakra wɔ ``(HFS)'' ho. Nanso kae sɛ ɛnyɛ obiara a ɔnom nnuru yi na obenya bi.

Dɛn ne asiane ahorow a ɛma obi nya ``Hand-Foot Syndrome''?

Ade titiriw ne `(chemotherapy)` aduru dodow a wɔde ma wo ne ɔkwan a wɔfa so de ma . Susuw ho hwɛ, sɛ `(chemotherapy)` aduru dodow a wɔde ma wo no dɔɔso, anaasɛ worenom aduru no bere nyinaa a, hokwan a ɛwɔ hɔ sɛ wubenya saa tebea yi no yɛ kɛse. Ɛne sɛ, sɛ wowɔ `(chemotherapy)` nnuru pii wɔ wo nipadua mu bere tenten a, asiane a ɛwɔ hɔ sɛ wubenya `(HFS)` no yɛ kɛse.

Dɛn ne ``Hand-Foot Syndrome'' ho sɛnkyerɛnne? Yɛyɛ dɛn hu no?

Mpɛn pii no, saa sɛnkyerɛnne ahorow yi fi ase da adi wɔ adapɛn abien kosi abiɛsa akyi bere a wɔafi nnuru a wɔde sa yare ase no. Mfiase no, ebia wobɛte nka sɛ wo nsa ne wo nan ho ayɛ wo yaw kakra. Akyiri yi, ebia wubehu sɛnkyerɛnne ahorow te sɛ:

• Nsa ne anan a ɛho ahonhon na ne kɔla sesa: Nnipa a wɔn honam ani yɛ fitaa, anaa wɔn a melanin nni wɔn mu pii no betumi ahu sɛ wɔn nsateaa ne wɔn nan ase ayɛ kɔkɔɔ (te sɛ owia hyew). Ebia nnipa a wɔn honam ani yɛ bruu anaa tuntum, anaa wɔn a melanin dɔɔso no behu sɛ wɔn nsateaa ne wɔn nan ase honam ani yɛ tuntum.
• Nsateaa ano a ɛho ahonhon: Ebia wohu sɛ ɛho ahonhon kɛse, titiriw wɔ mmeae te sɛ nsateaa ano aduru no.
• Wo honam ani a ɛyɛ den, ɛyɛ yaw, anaa ɛyaw bere a wɔde wɔn nsa ka no: Sɛ obi de ne nsa ka honam ani a, ebetumi ate nka sɛ ɛyɛ den anaasɛ ɛbɛyɛ yaw.
• Wora a ɛyɛ kurukuruwa anaasɛ ɛho ayɛ kurukuruwa: Ɛtɔ mmere bi a, honam ani betumi ayɛ kurukuruwa na ɛho ayɛ kurukuruwa.
• Ɛyaw bere a wo nsateaa anaa nan ase bɔ biribi: Sɛ nhwɛso no, ebia wobɛte ɛyaw nka bere a wonam anaa wode wo nsa ka biribi no.

Ebia saa sɛnkyerɛnne ahorow yi bɛyɛ nea emu nyɛ den koraa na ɛnyɛ yaw mma ebinom, bere a afoforo nso betumi ate ɛyaw a emu yɛ den a ɛmma wontumi nyɛ da biara da dwumadi ahorow.

Ɔkwan bɛn so na nnuruyɛfo hu ``Hand-Foot Syndrome''?

Sɛ wo duruyɛfo anaa ɔyarehwɛfo hu saa sɛnkyerɛnne ahorow yi bere a worenya nnuru a wɔde sa yare no a, wobesusuw sɛ ɛyɛ Nsa ne Nan Yare.

Nanso, sɛ wo nso worenom kokoram aduru bi a wɔfrɛ no `(multikinase inhibitors)` a, ɛsɛ sɛ wo duruyɛfo susuw biribi foforo ho. Ɛno yɛ tebea bi a wɔfrɛ no `(Hand-Foot Skin Reaction - HFSR)`. Eyi nso yɛ `(multikinase inhibitors)` ho nsunsuanso bɔne. `(HFSR)` nso ma honam ani nsakrae ba. Sɛ nhwɛso no, honam ani a ɛyɛ yaw, ɛyɛ den na ɛyɛ kɔkɔɔ betumi ayɛ mmeae te sɛ nkwaa, nan ase, ne nsateaa.

Esiane eyi nti, ɛtɔ mmere bi a oduruyɛfo betumi agye honam ani nkwammoaa afi wo nsam na ɔde afiri a wɔde hwɛ nneɛma nketenkete ahwɛ mu de ahu sɛ ebia wowɔ HFS anaa HFSR ankasa.

So ɔkwan bi wɔ hɔ a wɔbɛfa so asusuw sɛnea ``Nsa-Nanam Yare'' no mu yɛ den?

Yiw, Ɔman Kokoram Asoɛe no de ɔkwan bi a wɔfa so kyerɛ sɛnea tebea yi mu yɛ den no aba, a wɔfrɛ no nhyehyɛe a wɔde kyerɛ sɛnea tebea yi mu yɛ den . Wo duruyɛfo begyina wo HFS abasobɔde so asi sɛnea ɔbɛsa wo yare no ho gyinae.

• `(Grade 1) Hand-Foot Syndrome`: Ebia nsateaa ne nan ase ahonhon na ne kɔla bɛsakra (ayɛ kɔkɔɔ anaa ayɛ tuntum), nanso ɛyaw biara nni hɔ .
• `(Grade 2) Hand-Foot Syndrome`: Wɔ `(Grade 1)` ho sɛnkyerɛnne akyi no, ebia akisikuru, mogya a ɛbɛtɔ, ne honam ani a ɛrepaapae. Ebia ɛyaw bi wɔ hɔ a ɛma ɛyɛ den sɛ wobɛyɛ da biara da dwumadi ahorow .
• `(Grade 3) Hand-Foot Syndrome`: Nsɛnkyerɛnne no mu yɛ den sen nea ɛwɔ `(Grade 2)`. Ɛyaw no betumi ayɛ kɛse araa ma wontumi nyɛ nnwuma a ɛfata mpo . Ebetumi ayɛ den sɛ wobɛhyɛ ntade, aguare, anaa wobɛkɔ tiafi.

Dɛn ne ayaresa a wɔde sa `(Hand-Foot Syndrome)`?

Afei ma yɛnhwɛ nea eyi betumi ayɛ. Sɛ wo sɛnkyerɛnne ahorow no mu yɛ den yiye, a ɛkyerɛ sɛ ɛreka w’asetra araa ma wuntumi ntra ase sɛnea ɛsɛ a, ebia wo nnuruyɛfo besi gyinae sɛ wobegyae nnuru a wɔde sa yare no kakra, wɔbɛtew dodow a wɔde ma no so, anaasɛ wɔbɛsesa wo akɔ aduru foforo so.

Nanso, ɛtɔ mmere bi a nsakrae yi a wɔbɛyɛ no betumi anya kokoram ayaresa a edi mu no so nkɛntɛnso ketewaa bi. Sɛ ɛba saa a, sɛ wo yare no ho sɛnkyerɛnne no mu nyɛ den dodo a, ebia wo duruyɛfo bɛkamfo akwan horow a wobɛfa so adi nea efi mu ba no ho dwuma.

Dɛn na yebetumi ayɛ de adi sɛnkyerɛnne ahorow no so?

Nnipa pii betumi adi Hand-Foot Syndrome ho sɛnkyerɛnne ahorow ho dwuma denam asetra mu nsakrae a ɛnyɛ den bi a wɔbɛyɛ so. Wubetumi anya ahotɔ denam nea edidi so yi a wobɛyɛ so:

• Fa corticosteroid aduru di dwuma: Oduruyɛfo betumi akyerɛw saa aduru yi na ama ɔfe ne ɔfe no so atew.
• Fa moisturizers - emollients gu so: Sɛnea ɛbɛyɛ a wo honam ani renyow na ama nsuo atɔ mu yie no, ɛho hia sɛ wode moisturizer di dwuma. Wɔsan frɛ eyinom sɛ nneɛma a ɛma nipadua no yɛ mmerɛw. Fa gu so mpɛn pii da biara.
• Fa nnuru a wɔde kum ɛyaw di dwuma: Wubetumi anom nnuru a wɔnom anaa nnuru a wɔde gu nipadua no so de asa ɛyaw, sɛnea wo duruyɛfo akyerɛ wo no.
• Bɔ wo honam ani ho ban mfi ɔhyew ho: Sɛ nhwɛso no, brɛ owia, aguare a ɛyɛ hyew, ne wo nan a wode bɛhyɛ nsu a ɛyɛ hyew mu.
• Fa nsukyenee anaa ntama a ɛyɛ nwini gu so: Sɛnea ɛbɛyɛ a mogya a ɛbɛkɔ wo nsa ne wo nan so no so atew no, fa nsukyenee anaa ntama a ɛho tew a wɔde nsuonwini afra mu gu wo nsateaa ne wo nansoaa so bɛyɛ simma 15-20. Nanso mfa nsukyenee no nhyɛ wo honam ani tẽẽ, fa ntama kyekyere.
• Ma wo nsa ne wo nan nkɔ soro: Sɛ wote akongua so a, ma wo nan so, na sɛ woda a, fa pillow to wo nan ase. Saa ara na ɛte wɔ w’abasa ho.
• Fa wo honam ani brɛoo hyɛ wo honam ani: Sɛ́ ebia wode aduru a wɔde hyɛ wo honam ani anaasɛ wode mpopaho rehohoro wo honam ani no, nsɛe wo honam ani denneennen dodo, bɔ wo honam ani brɛoo.
• Hyɛ sɔks ne mpaboa a emu yɛ hare a ɛnyɛ den: Hyɛ sɔks a ɛnyɛ den, a wɔde ade te sɛ kotoku ayɛ. Saa ara na ɛte wɔ mpaboa ho, na mpɛn pii no, biribi a emu yɛ hare te sɛ mpaboa ye sen biara.

Ade a ɛho hia sen biara ne sɛ wobɛtew akasakasa a ɛda wo nsa ne wo nan ase ntam no so.

Kwati sɛ wobɛyɛ nneɛma a ɛte sɛɛ, anyɛ yiye koraa no bere tiaa bi:

• Mmirikatu: Efisɛ wo nan ase rebɔ fam bere nyinaa.
• Adwuma a wɔyɛ bere a wokura nnwinnade no mu denneennen no:
• Kura sekan no mu denneennen bere a woretwitwa nhabannuru no.
• Nnwinnade te sɛ agyan ne agyan a wɔde bedi dwuma bere a woreyɛ adwuma wɔ turo mu no.
• Akode a wode bedi dwuma bere a woreyɛ ofie nsiesie (e.g. hama a wokura bere a woreka nnade).
• Nneɛma a emu yɛ duru a wɔma so.

Dɛn ne aduru a eye sen biara a wɔde sa `(Hand-Foot Syndrome)`?

Nnuru a wɔde yɛ aduru a ɛnyɛ huam, a nsa nnimYi. Nsã betumi ama honam ani ayow kɛse, na ɛno betumi ama yare no ho sɛnkyerɛnne no asɛe kɛse. Nhwehwɛmu ahorow bi kyerɛ sɛ sɛ wɔde cream a urea 10% wom gu so mprɛnsa da biara a, ebetumi aboa ma honam ani ahotɔ na ama honam ani ayɛ nwini. Nanso, ɛbɛyɛ papa sɛ wobɛkɔ oduruyɛfo nkyɛn ansa na wode aduru biara a wɔde hyɛ wo ho adi dwuma.

Bere a magyae ayaresa no akyi no, me ho bɛtɔ me ntɛm dɛn?

Eyi betumi ayɛ soronko wɔ onipa biara ho. Nanso, mpɛn pii no, saa sɛnkyerɛnne ahorow yi brɛ ase nkakrankakra wɔ adapɛn abien kosi anum akyi bere a wɔagyae nnuru a wɔde sa yare no. Ebia ebegye nna kakraa bi bio ansa na ne ho atɔ no koraa.

So akwan bi wɔ hɔ a wobetumi afa so asiw Nsa ne Nan Yare no ano?

Ɛwom sɛ wontumi nsiw ano koraa de, nanso nneɛma bi wɔ hɔ a wubetumi ayɛ de atew asiane no so na sɛ ɛba a, tebea no ansɛe.

• Sɛ wowɔ honam ani haw biara (e.g. honam ani a ɛyɛ mmerɛw, honam ani a apaapae) a, nyansa wom sɛ wobɛma wɔasa ansa na woafi nnuru a wɔde sa yare ase.
• Akwan pii a wɔfa so di sɛnkyerɛnne ahorow a yɛadi kan aka ho asɛm no ho dwuma nso boa ma wosiw `(HFS)` mfiase ano.
• Sɛ nhwɛso no, ebia oduruyɛfo bi bɛka akyerɛ wo sɛ fa aduru a ɛma wo ho yɛ hyew di dwuma fi da a wubefi ase ayɛ nnuru no.
• Nneɛma a wubetumi adi kan ayɛ ne sɛ wobɛbɔ wo honam ani ho ban afi ɔhyew ho na woakwati dwumadi ahorow a ɛde nhyɛso ne akasakasa a ɛho nhia ba wo nsateaa ne wo nan ase.

Dɛn na obi a ɔwɔ ``Hand-Foot Syndrome'' nya?

Nokwarem no, ɛnyɛ obiara na saa ``Hand-Foot Syndrome`` yi ka no wɔ ɔkwan koro no ara so. Sɛ wɔnom ``(chemotherapy)`` aduru koro no ara mpo a, ɔkwan a obi fa so te nka no betumi ayɛ soronko koraa wɔ ɔkwan a obi foforo fa so te nka no ho. Wɔ ebinom fam no, ebia ɛbɛyɛ ɔhaw ketewaa bi kɛkɛ, bere a ebinom fam no, ebetumi ayɛ nea emu yɛ den araa ma ɛsɛ sɛ wɔsesa wɔn kokoram ayaresa.

Nea eye sen biara ne sɛ, mpɛn pii no, saa sɛnkyerɛnne ahorow yi fi hɔ bere a wɔawie nnuru a wɔde sa yare no . Sɛ wohwɛ wo honam ani yiye a, wubetumi nso asiw nsunsuanso a ɛtra hɔ kyɛ te sɛ akuru ano.

So Hand-Foot Syndrome betumi de nsɛnnennen afoforo aba?

Ade biako ne sɛ nnipa binom nsateaa hwere kakra. Eyi betumi ayɛ ɔhaw kakra wɔ mmere bi mu. Sɛ nhwɛso no, bere a wuhia nsateaa nkyerɛwee bere a worekɔ amannɔne, te sɛ bere a worebisa visa no. Nanso mma ɛnhaw wo, wo nsateaa nkyerɛwee bɛsan anyin wɔ asram kakraa bi mu bere a wɔawie ayaresa no.

Bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn?

Ɛho hia yiye sɛ wobɛbɔ wo duruyɛfo amanneɛ wɔ sɛnkyerɛnne biara a wubehu bere a worenya nnuru a wɔde sa yare no ho, ɛmfa ho sɛnea ɛyɛ ketewaa bi no. Titiriw no, hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo sɛ:

• Sɛ sɛnkyerɛnne ahorow no kɔ soro nkakrankakra a.
• Sɛ honam ani paapae a, honam ani retu na mogya retu.
• Sɛ wo sɛnkyerɛnne ma ɛyɛ den sɛ wobɛyɛ wo da biara da dwumadi ahorow a.

Wɔ mmere a ɛte sɛɛ mu no, sɛ woka kyerɛ oduruyɛfo no , obetumi ama wo ayaresa a wuhia, anaasɛ wayɛ nsakrae wɔ wo nnuru a wode sa yare no mu.

Nsɛm bɛn na ɛsɛ sɛ mibisa oduruyɛfo no?

Ɛbɛboa wo paa sɛ wubebisa wo duruyɛfo anaa ɔyarehwɛfo nsɛm te sɛ eyinom:

• Nsunsuanso bɔne bɛn na metumi ahwɛ kwan bere a merenom nnuru a wɔde sa yare no?
• Nneɛma bɔne bɛn na ɛsɛ sɛ mema wohu?
• Nneɛma bɔne bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn anaa mekɔ ayaresabea?
• So nneɛma bi wɔ hɔ a metumi ayɛ de asiw nsunsuanso bɔne no bi ano?
• So nneɛma titiriw bi wɔ hɔ (te sɛ aduru a wɔde hyɛ nipadua mu, nnuru a wɔde yɛ aduru) a wokamfo kyerɛ sɛ wɔde besiw anaa wɔde siw ``Nsa-Nan Ho Yare'' yi ano?

Awiei koraa no, nea ɛsɛ sɛ wokae (Take-Home Message) .

Enti, `(chemotherapy)` yɛ aduru a ɛho hia yiye, a egye nkwa ma kokoram. Nanso, ɛsɛ sɛ yɛte ase nso sɛ saa nneɛma bɔne yi betumi aba. `(Hand-Foot Syndrome)` nso yɛ tebea a abu so, nanso mpɛn pii no wotumi di ho dwuma.

Sɛ wowɔ saa sɛnkyerɛnne ahorow yi a , mma wo ho nnyɛ wo hu anaasɛ wo ho nnyɛ wo hu . Ade a ɛho hia sen biara ne sɛ wo ne w’akwahosan kuw no bɛka eyi ho asɛm pefee. Wɔbɛboa wo ma woadi wo tebea no ho dwuma na sɛ ɛho hia a, woayɛ nsakrae wɔ w’ayaresa nhyehyɛe no mu. Ɛnyɛ wo nko ara, na wowɔ akwahosan ho adwumayɛfo kuw a nnuruyɛfo, ayarehwɛfo, ne adwumayɛfo afoforo wom a wɔbɛboa wo wɔ akwantu yi mu. Enti, hwehwɛ wɔn mmoa sɛ wowɔ biribi a ɛhaw wo a.

` Nsa-Nan Syndrome, HFS, nnuru a wɔde sa yare, nea efi mu ba, honam ani adeyɛ, nsateaa-asen mu erythrodysesthesia, kokoram ayaresa, kokoram ayaresa, nsunsuanso bɔne, honam ani yare, nsateaa a ɛyɛ hyew, nsateaa a ɛyɛ hyew