So eyi yɛ nyarewa pii a wɔaka abom? Momma yensua Mixed Connective Tissue Disease (MCTD) ho ade.

Ɛtɔ mmere bi a, wote nka sɛ woabrɛ paa, wo nkwaa yɛ wo yaw, na wo nsateaa ahonhon? Nna bi wɔ hɔ a wo honam ani yɛ kurukuruwa, na nna foforo nso wote nka sɛ wo home yɛ wo yaw kakra. Saa nsɛnkyerɛnne yi betumi ayɛ te sɛ nyarewa afoforo de, enti ebia woresusuw ho sɛ, "Dɛn na ɛhaw me?" Ebia wuntumi nhu sɛ eyi yɛ yare biako anaa nyarewa a wɔaka abom. Ɛnnɛ yɛbɛka tebea bi a ɛde saa sɛnkyerɛnne ahorow yi pii bom ba ho asɛm, a ɛyɛ den kakra, nanso ɛho hia sɛ wohu. Wɔfrɛ eyi sɛ Mixed Connective Tissue Disease (MCTD).

Sɛ yɛbɛka no tiawa a, dɛn ne MCTD?

MCTD yɛ ɔyare a ɛntaa nsi a nipadua no tumi ko tia nyarewa . Okay, enti dɛn ne autoimmune disorder? Sɛ yɛbɛka no tiawa a, yɛwɔ tumi a ɛko tia nyarewa wɔ yɛn nipadua mu. Ɛte sɛ asraafo dɔm wɔ yɛn man mu. N’adwuma ne sɛ ebehu atamfo te sɛ mmoawa, mmoawa, ne mmoawa a wɔhyɛn nipadua no mu na wɔbɔ yɛn ho ban fi nyarewa ho na ɛtow hyɛ wɔn so. Nanso ɛtɔ mmere bi a, yɛn ankasa ahobammɔ no kɔ bɔne. Sɛ́ anka wɔbɛyɛ ahɔho atamfo no, wodi mfomso bu yɛn ankasa ntini ne nkwammoaa a ɛte apɔw sɛ "atamfo" na wofi ase tow hyɛ wɔn so. Ɛno ne nea yɛfrɛ no autoimmune disease.

Nea ɛkɔ so wɔ MCTD mu ne sɛ ntini mu nyarewa atitiriw abiɛsa ho sɛnkyerɛnne ahorow no bom. Ɛno nti na wɔfrɛ no "mixed." Nyarewa abiɛsa no ne:

• Systemic lupus erythematosus (SLE): Eyi ne yare a yɛtaa frɛ no "lupus" tiawa.
• Scleroderma: Eyi titiriw ne honam ani a ɛyɛ den na ɛyɛ den.
• Polymyositis: Eyi ma ntini ahorow no yɛ mmerɛw na ɛyɛ hyew.

Wɔ nyarewa atitiriw abiɛsa yi akyi no, nnipa binom nso betumi anya ntini a ɛka bom yɛ nyarewa afoforo te sɛ honam ani ntini mu yare , ntini mu yare , anaa Sjögren yare ho sɛnkyerɛnne . Ɛno nti na nnuruyɛfo frɛ tebea yi "Overlap Syndrome," anaa tebea a nyarewa pii ka bom.

Dɛn ne MCTD ho sɛnkyerɛnne ahorow?

Nsɛnnennen akɛse a ɛwɔ eyi mu biako ne sɛ yare no ho sɛnkyerɛnne ahorow no nna adi prɛko pɛ. Wobetumi ada adi bere a bere kɔ so no, mmiako mmiako. Enti ebetumi ayɛ den kakra sɛ wubehu sɛ ɛyɛ MCTD wɔ mfiase no. Momma yɛnhwɛ sɛnkyerɛnne atitiriw a wubehu no.

MCTD te nka dɛn bere a ɔyare no rehyew no?

Ɛnyɛ bere nyinaa na obi a ɔwɔ MCTD no te nka saa ara. Ɛtɔ mmere bi a, yare no ho sɛnkyerɛnne no betumi ano abrɛ ase na ayɛ nea ɛfata. Nanso mmere foforo nso yare no mu yɛ den mpofirim. Yɛfrɛ eyi `flare-up`. Saa mmere yi mu no, ebia wo yare no ho sɛnkyerɛnne no bɛyɛ kɛse kakra.

• Ebia ɛyaw a emu yɛ den na ɛho ahonhon wɔ nkwaa no mu. Te sɛ obi a ɔwɔ ntini mu yare no, ebia nkwaa no mu yɛ den na ɛyɛ yaw araa ma wontumi nkotow wɔn nsateaa anɔpa.
• Raynaud adeyɛ no betumi ayɛ nea emu yɛ den yiye. Atiridii kakra mpo betumi ama nsateaa no ayɛ mmerɛw mpofirim, nkwa nnim, na ne kɔla asesa.
• Ebia wobɛte nka sɛ woabrɛ paa , te sɛ nea woanya atiridii nna pii, na wo ntini mu yɛ wo yaw na wote nka sɛ woayɛ mmerɛw dodo sɛ wobɛyɛ biribiara.

Dɛn na ɛde MCTD ba? Hena na ɔwɔ asiane mu kɛse?

Nokwarem no, nhwehwɛmufo nnya nhuu nea ɛde MCTD ba ankasa . Ɛnyɛ yare a efi awofo hɔ kɔ mmofra mu tẽẽ, a ɛkyerɛ sɛ efi awosu mu. Nanso, wɔahu sɛ sɛ obi a ɔwɔ abusua no mu wɔ ntini a ɛka bom yɛ adwuma foforo a, ebia afoforo nso betumi anya saa yare yi kakra.

Sɛ ɛno da nkyɛn a, misusuw sɛ ebia nneɛma bi a efi akyi nso renya eyi so nkɛntɛnso.

• Nyarewa bi a efi mmoawa mu ba .
• Nnuru bi a wɔde wɔn ho bɛhyɛ mu , te sɛ polyvinyl chloride ne silica.

Ɛwom sɛ yare yi betumi anya mfe biara de, nanso wɔtaa hu no wɔ mmea a wɔadi fi mfe 20 kosi 30 so .

Nsɛnnennen bɛn na ebetumi aba esiane MCTD nti?

MCTD nyɛ nkwaa mu yare ara kwa. Sɛ wɔansa a, ebetumi asɛe akwaa a ɛho hia na ɛde nsɛnnennen a emu yɛ den aba. Enti, ɛho hia paa sɛ yehu eyi.

Nsɛnnennen atitiriw a ebetumi aba ne:

• Ahurututu mu mogya mmoroso: Eyi ne ɔhaw a asiane wom sen biara a ɛba wɔ MCTD mu. Sɛ yɛbɛka no tiawa a, ɛyɛ nhyɛso a ɛkɔ soro wɔ mogya ntini a ɛde mogya fi koma no mu kɔ ahurututu mu no mu. Eyi de ɔhaw kɛse ba koma no so na ebetumi de tebea horow a emu yɛ den te sɛ koma a entumi nyɛ adwuma aba. Saa tebea yi ne ade titiriw a ɛma MCTD ayarefo wuwu.
• Ahurututu mu yare a ɛwɔ ntam: Ahurututu mu ntini a ɛyɛ hyew na ɛyɛ akuru, na ebetumi ama ayɛ den sɛ ɔbɛhome.
• Koma mu yare
• Asaabo a ɛsɛe
• Nnuan a wɔyam no asɛe
• Mogya a ɛtɔ kɔ nipadua mu
• Ntini mu owu (necrosis) .
• Aso a ɛyɛ mmerɛw

Ɔkwan bɛn so na nnuruyɛfo hu yare yi pɛpɛɛpɛ?

Sɛnea yɛadi kan aka ho asɛm no, MCTD ho sɛnkyerɛnne betumi ada adi mmiako mmiako bere a bere kɔ so no, na ɛma ɛyɛ den ma nnuruyɛfo sɛ wobehu. Ebetumi agye mfe pii ansa na wɔasi so dua sɛ ɛyɛ MCTD. Oduruyɛfo bi wɔ hɔ a ne ho akokwaw wɔ tebea horow yi mu, a wɔfrɛ no akisikuru ho ɔyaresafo . Sɛ wowɔ saa sɛnkyerɛnne ahorow yi a, ɛda adi sɛ wo duruyɛfo de wo bɛkɔ nnuruyɛfo atitiriw yi mu biako nkyɛn.

Nneɛma atitiriw anan na ɛboa ma wohu nsonsonoe a ɛda MCTD ntam wɔ ntini a ɛka bom yɛ nyarewa afoforo ho:

1. Nkwammoaa bi a wɔfrɛ no anti-U1-RNP a ɛdɔɔso wɔ mogya no mu: Wobetumi de mogya mu nhwehwɛmu titiriw bi ahu eyi. Saa antibody yi yɛ MCTD ayarefo pɔtee.

2. Asaabo ne ntini a ɛwɔ nipadua no mfinimfini ho haw a emu yɛ den a enni hɔ: Saa ɔhaw ahorow yi abu so wɔ lupus (SLE) mu. Nanso, wɔntaa nhu wɔ MCTD mu.

3. Ntini mu yare a emu yɛ den ne ahurututu mu mogya mmoroso a ɛwɔ hɔ: Saa sɛnkyerɛnne ahorow yi abu so wɔ MCTD mu sen lupus anaa scleroderma nkutoo mu.

4. Raynaud adeyɛ ne nsateaa a ɛho ahonhon: Ɛwom sɛ lupus ayarefo 25% pɛ na wɔwɔ saa sɛnkyerɛnne ahorow yi de, nanso abu so kɛse wɔ MCTD ayarefo mu.

Dɛn ne ayaresa ahorow a wɔde sa MCTD?

Nea edi kan koraa no, wonni aduru biara a wɔde sa MCTD. Nanso mma ɛnhaw wo. Ayaresa ahorow pii wɔ hɔ a etu mpɔn a ebetumi aboa wo ma woadi wo yare no ho sɛnkyerɛnne ahorow ho dwuma, asiw nsɛnnennen ano, na woabɔ bra sɛnea ɛsɛ. Ayaresa no gyina sɛnea wo yare no ho sɛnkyerɛnne te, sɛnea wo tebea no mu yɛ den, ne akwaa a ɛka wo no so.

Wobɛyɛ dɛn atumi ahwɛ wo ho?

Wɔ nnuru a wo duruyɛfo akyerɛw ama wo akyi no, nsakrae nketenkete a wobɛyɛ wɔ w’asetra kwan mu no betumi ama yare yi a wobɛtra ase ayɛ mmerɛw kɛse.

• Nnuru a wɔde kum ɛyaw a wɔde di dwuma: Sɛ ɛyaw ne ɔfe a emu nyɛ den a, wubetumi ne wo duruyɛfo akasa afa nnuru a ɛnyɛ steroid a ɛko tia ɔyare mmoawa (NSAIDs) - te sɛ ibuprofen - a wobɛnom sɛ nhwɛso no ho. Nanso fa eyinom nni dwuma bere nyinaa da a wonkɔ oduruyɛfo nkyɛn .
• Bɔ wo nsa ho ban fi awɔw ho: Eyi ho hia yiye sɛ wowɔ Raynaud adeyɛ no a. Hyɛ nsateaa wɔ nna a awɔw wom. Ma wo nsa nyɛ hyew bere a wowɔ AC adan mu no. Hwɛ yiye bere a woreyi nneɛma afi frigye mu no.
• Kwati sigaretnom koraa: Sigaretnom ma mogya ntini no mu yɛ den kɛse, na ɛno betumi ama Raynaud adeyɛ no asɛe kɛse.
• Tew adwennwen so: Adwennwen yɛ ade titiriw a ɛde Raynaud yare no ba. Enti bɔ mmɔden sɛ wobɛma w’adwene adwo denam nneɛma te sɛ ahomegye ne nsusuwii a wobɛyɛ so. Sɛ ɛho hia a, ɛbɛyɛ papa nso sɛ wobɛhwehwɛ mmoa afi adwenemyare ho ɔfotufo bi hɔ.

MCTD a wɔde traa ase bere tenten

Esiane sɛ MCTD yɛ tebea a ɛtra hɔ kyɛ nti, ɛho hia sɛ wusua sɛ wo ne no bɛtra ase. Titiriw sɛ obi nom nnuru te sɛ corticosteroids bere tenten a, ebetumi afi so nkɛntɛnso bɔne bi.

• Nnompe a ɛyɛ mmerɛw esiane nnompe mu yare nti.
• Ntini a ewu esiane mogya a ɛkɔ ntini ahorow mu a ɛso tew nti.
• Ntini mu mmerɛwyɛ.
• Ɛnyɛ den sɛ ɔyare mmoawa betumi anya bi.

Sɛ ɔbea bi a ɔwɔ MCTD reyɛ nhyehyɛe sɛ ɔbɛwo akokoaa a, ɛho hia sɛ odi kan ne ne duruyɛfo kasa . Tebea no betumi asɛe kɛse bere a wɔyem no. Afei nso, ebia nkokoaa a ɛnanom a wɔwɔ MCTD woo wɔn no mu duru sua wɔ awo mu.

Bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn?

Sɛ wowɔ sɛnkyerɛnne ahorow a wɔaka ho asɛm wɔ asɛm yi mu no bi, titiriw sɛ ɛrehaw wo da biara da dwumadi ahorow a, akyinnye biara nni ho sɛ ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn. Sɛ wowɔ nkwaa anaa ntini mu ɛyaw foforo biara, wo nsateaa mu ahonhon, anaasɛ `Raynaud adeyɛ` ho sɛnkyerɛnne a, hwehwɛ aduruyɛ mu afotu.

Sɛ wokɔ oduruyɛfo nkyɛn a, wubetumi abisa nsɛm yi:

• Dɛn na ɛde me sɛnkyerɛnne ahorow no ba?
• So mewɔ ntini a ɛka bom yɛ yare bɛboro biako?
• Sɔhwɛ ahorow bɛn na ɛsɛ sɛ meyɛ?
• Dɛn ne ayaresa ahorow a wɔde sa me tebea no?
• Dɛn na metumi ayɛ na yare no ansɛe?

Esiane sɛ wo ne saa yare yi te ase nti, ebia wubesusuw sɛnea w’asetra bɛyɛ wɔ mfe 10 akyi no ho. Nsɛm a wɔanya kyerɛ sɛ sɛ wɔsa wɔn yare yiye a, anyɛ yiye koraa no, ayarefo bɛyɛ 80% betumi atra ase mfe 10 wɔ bere a wɔahu wɔn yare no akyi. Nanso w’ankasa oduruyɛfo nkutoo na obetumi ama wo eyi ho nsɛm a eye sen biara na ɛyɛ nokware sen biara . Efisɛ egyina nneɛma pii so, te sɛ sɛnea wo yare no te ne akwaa a ɛka wo no.