So wo nnompe ayɛ mmerɛw na ɛyɛ yaw? Momma yensua eyi ho ade (Osteitis Fibrosa Cystica - OFC)!

So ɛtɔ mmere bi a wote ɛyaw ne ɛyaw nka wɔ wo nipadua mu, titiriw wɔ wo nnompe mu? Anaasɛ wote nka sɛ wo nnompe rebubu wɔ ade ketewaa bi mpo mu? Ebia tebea bi wɔ saa nneɛma yi akyi a yɛnka ho asɛm pii, nanso ɛho hia sɛ yehu. Tebea a ɛte saa no biako ne `(Osteitis Fibrosa Cystica - OFC)`. Ɛwom sɛ ebia ɛbɛyɛ te sɛ nea edin yi yɛ den kakra de, nanso momma yɛnkyerɛkyerɛ mu tiawa.

Dɛn ne Nnompe mu Nyarewa (OFC)?

Sɛ yɛbɛka no tiawa a, `(Osteitis Fibrosa Cystica - OFC)` yɛ yareɛ a ɛntaa nsi a ɛka yɛn nnompe. Ɛne parathyroid ntini a ɛwɔ yɛn nipadua mu no wɔ abusuabɔ tẽẽ. Woate thyroid ntini no ho asɛm. N’akyi no, saa parathyroid ntini anan yi wɔ hɔ. Saa ntini yi yɛ parathyroid hormone (`Parathyroid Hormone - PTH`) .

Saa `(PTH)` hormone yi ho hia na ama yɛn nnompe ayɛ den na ayɛ apɔwmuden. Ɛboa nso ma wɔhyɛ calcium dodow a ɛwɔ mogya no mu no so. Nanso, susuw ho hwɛ, sɛ wɔyɛ saa `(PTH)` hormone yi dodo, kyerɛ sɛ, ɛboro so a, dɛn na ɛba? Ɛno na ɔhaw no fi ase. Esiane saa `(PTH)` a ɛboro so no nti, sɛ́ anka wɔbɛhyɛ nnompe no den no, efi ase yɛ mmerɛw nkakrankakra . Bere kɔ so no, nnompe no nsusuwii betumi asesa, na nneɛma te sɛ ntokuru (te sɛ akisikuru a nsu ahyɛ mu ma) nso betumi ayɛ mu.

Saa PTH a ɛboro so yi betumi ama calcium dodow a ɛwɔ mogya no mu akɔ soro, na ama asaabo mu abo aba, mogya mmoroso (nhyɛso a ɛkɔ soro), ne koma a entumi nyɛ adwuma yiye.

Wɔde din afoforo pii frɛ tebea no `(OFC)`. Ebia woate din ahorow yi:

• ``Von Recklinghausen yare a ɛfa nnompe ho''.
• `Nnompe mu yare`
• `Cystica a wɔayɛ no nyinaa`
• `Nnompe mu yare a ɛma obi ho yɛ hyew`
• Brown tumor of bone . Mma edin yi nnyɛ wo hu. Ɛwom sɛ ɛka sɛ `(Tumor)` de, nanso ɛnyɛ ``Cancerous``. Wɔde saa din yi di dwuma efisɛ nnipa a wɔwɔ `(OFC)` no wɔ nsensanee bruu a ɛda adi esiane mogya a ɛretu ne nhama a ɛwɔ wɔn nnompe mu nti. Nanso ɛnyɛ kokoram `(Tumor)` ankasa.

Nsɛmfua "(Osteitis Fibrosa Cystica)" kyerɛ biribi te sɛ 'nnompe a ɛbɔ ne cyst a ɛba'. Enti, sɛ `(PTH)` dodow no kɔ soro a, nnompe no betumi asɛe bere biara. Nanso, sɛ wohu saa tebea yi a wɔfrɛ no `(Hyperparathyroidism)` (i.e. `(PTH)` a wɔyɛ boro so) na wɔsa no ntɛm a, wobetumi asa `(OFC)` tebea no anaasɛ wɔasiw ano.

Saa (OFC) tebea yi abu so dɛn?

Afei ebia woresusuw sɛnea yare yi abu so no ho. Nokwarem no, ɛntaa nsi koraa wɔ aman a akwahosan ho nhyehyɛe pa wom mu . Sɛ nhwɛso no, wɔ United States mpo no, nnipa a wɔwɔ hyperparathyroidism no mu nnu 5% na wonya OFC. Wɔtaa hu wɔ nnipa a wɔwɔ hyperparathyroidism a emu yɛ den a wɔansa wɔn yare bere tenten no so.

Nanso bere bi a atwam no, na eyi abu so kɛse. Bɛyɛ mfeɛ aduonum a atwam no, nnipa a wɔwɔ ``Hyperparathyroidism'' no mu bɛyɛ 69% na na wɔwɔ saa nnompe yareɛ yi. Nanso esiane sɛ aduruyɛ ho nyansahu anya nkɔso nti, titiriw bere a ``Mogya mu Nhwehwɛmu a Wɔyɛ Daa'' aba no, wɔatumi ahu saa tebea horow yi na wɔasa no ntɛmntɛm. So ɛno nyɛ ade kɛse?

Dɛn ne saa (OFC) tebea yi ho sɛnkyerɛnne?

Okay, afei momma yɛnhwɛ sɛnkyerɛnne ahorow a ebetumi aba wɔ tebea `(Osteitis Fibrosa Cystica)` no mu.

Nsɛnkyerɛnne titiriw a ɛkyerɛ ne sɛ:

• Nnompe mu yaw . Eyi ne ade a edi kan a nnipa dodow no ara te nka. Ɛtɔ da bi mpo a, ebetumi ayɛ yaw sɛ wode wo nsa bɛka dompe no.
• Nneɛma a Abubu . Nnompe, titiriw nea ɛwɔ abasa, anan, anaa akyi berɛmo mu no tumi bubu ntɛmntɛm. Sɛ obi hwe ase kakra mpo a, ebetumi abubu dompe.

Saa tebea yi mfiase no, nsɛnkyerɛnne a edidi so yi nso betumi aba (eyinom nso betumi ayɛ ``Hyperparathyroidism'' ho sɛnkyerɛnne):

• Ɔbrɛ a wɔte nka bere nyinaa (`Ɔbrɛ`).
• Mrɛyɛ.
• Akisikuru ne ɔfe.
• Ayamtim.
• Nsu pii a wɔde fa mu sen sɛnea ɛte daa (`Polyuria`). Eyi kyerɛ sɛ ɛsɛ sɛ wɔkɔ tiafi mpɛn pii.

Sɛ wowɔ saa nsɛnkyerɛnne yi a, nnyɛ w'ankasa gyinaesi sɛ, "Oh, eyi yɛ `(OFC)'." Efisɛ saa sɛnkyerɛnne ahorow yi betumi aba nyarewa afoforo nso mu. Nanso ɛho hia yiye sɛ wuhu eyinom na woka kyerɛ oduruyɛfo.

Dɛn ne nneɛma a ɛde (OFC) ba?

Dɛn na ɛde Osteitis Fibrosa Cystica ba? Sɛnea madi kan aka no, nea ɛde eyi ba titiriw ne Hyperparathyroidism a wɔnsa . Ɛne sɛ, yɛn Parathyroid ntini ahorow no ma PTH pii. Eyi betumi asi wɔ akwan titiriw abien so:

1. Primary Hyperparathyroidism: Eyi fi ɔhaw bi a ɛwɔ wo parathyroid ntini mu. Saa ntini yi betumi ayɛ kokoram (kokoram) anaasɛ ɛwɔ nyin a ɛnyɛ kokoram (te sɛ adenoma) a ɛrema wɔayɛ PTH pii. Anaasɛ ebia ntini anan no nyinaa ayɛ kɛse (hyperplasia) na ayɛ hormone pii dodo.

2. Secondary Hyperparathyroidism: Eyi ba esiane akwahosan tebea foforo nti. Sɛ nhwɛso no, sɛ obi wɔ asaabo mu yare a enni sabea a, calcium ne vitamin D a ɛkari pɛ wɔ ne nipadua mu no sɛe. Afei, wɔ mmuaema mu no, parathyroid ntini no fi ase yɛ PTH pii. Afei nso, sɛ vitamin D ho yɛ na kɛse a, mogya mu calcium dodow so tew, enti parathyroid ntini no yɛ adwumaden kɛse ma calcium dodow no kɔ soro. Saa bere no, PTH hormone no kɔ soro, na bere kɔ so no, Osteitis Fibrosa Cystica betumi anya.

Wo de susuw ho hwɛ, na yɛn maame nuabea Kamala anya asaabo mu haw bere tenten. Wannom nnuru a ɛfata amma no. Bere bi akyi no, ne `(Parathyroid)` ntini ahorow a na ɛrepere sɛ ɛbɛhyɛ calcium a ɛwɔ ne nipadua mu no so no fii ase yɛɛ `(PTH)` pii sen sɛnea ɛsɛ sɛ ɛyɛ. Awiei koraa no, aunt Kamala nyaa `(OFC)` kaa nnompe mu yaw ho. So wote abusuabɔ a ɛda ntam no ase?

Dɛn ne nsɛnnennen a ebetumi aba wɔ (OFC) mu?

Nsɛnnennen atitiriw a ɛba wɔ hyperparathyroidism a wɔansa ne OFC mu no fi nnompe mu. Eyi kyerɛ ɛyaw, nnompe a ɛyɛ mmerɛw (nnompe a ɛsakra), na ɛnyɛ den sɛ ɛbɛbubu . Eyinom ne nneɛma a wotumi hu ntɛm ara. Ebia obi tenten so bɛtew mpo.

Nanso, eyi akyi no, nsɛnnennen afoforo betumi aba. Wɔne:

• Asaabo mu abo a ɛba.
• Asaabo a entumi nyɛ adwuma yiye.
• Ahoɔden a ɛba fam, ɔbrɛ a ɛba bere nyinaa.
• Yafunu mu yaw.
• Adwene mu haw ahorow te sɛ adwenemhaw.
• Nkae ne adwene a wɔde si biribi so ho haw ahorow.

Hwɛ baabi a ɔhaw bi a efi ase wɔ beae biako betumi akɔ. Ɔhaw bi a ɛwɔ yɛn nipadua nhyehyɛe biako mu betumi aka nhyehyɛe afoforo nso. Ɛno nti na ɛho hia sɛ wohu yare no ntɛm na wɔsa no yare no.

Ɔkwan bɛn so na wohu OFC?

Okay, afei ɛbɛyɛ dɛn na oduruyɛfo ahu saa tebea yi `(Osteitis Fibrosa Cystica)`?

Nea edi kan no, wo duruyɛfo no bɛkyerɛw w’akwahosan ho abakɔsɛm a edi mũ . Obebisa wo bere tenten a woanya saa sɛnkyerɛnne ahorow yi, sɛ ebia wowɔ ayaresa mu tebea afoforo (te sɛ asaabo mu yare) a ebetumi aka wo PTH dodow, ne nnuru a worenom. Afei, wɔbɛyɛ nipadua mu nhwehwɛmu de ahwɛ sɛ nnompe mu yaw, ɛyɛ mmerɛw, anaa dɛmdi bi anaa.

Nea ɛbɛyɛ na nnuruyɛfo asi yare no so dua no, wobetumi de nhwehwɛmu ahorow te sɛ:

• Mogya mu nhwehwɛmu: Eyinom hwɛ sɛ hormone ne mineral a ɛnkari pɛ anaa. Ne titiriw no, wɔhwehwɛ parathyroid hormone (PTH) dodow, calcium dodow, phosphorus dodow, vitamin D dodow, ne alkaline phosphatase (enzyme bi a efi nnompe mu) mu. Wɔ OFC mu no, PTH ne alkaline phosphatase dodow betumi ayɛ kɛse yiye.
• Nsu mu nhwehwɛmu: Wubetumi nso ahwɛ calcium dodow a ɛwɔ wo nsu mu.
• Mfoninitwa sɔhwɛ ahorow:
• X-ray: Eyinom betumi akyerɛ sɛnea nnompe no yɛ teateaa, nneɛma te sɛ akisikuru, ne sɛ ebia nnompe no mu abubu nketenkete paa (microfractures) anaa nsakrae a ɛda adi wɔ nnompe no mu (te sɛ subperiosteal resorption).
• CT Scans (`CT - Computed Tomography scans`) anaa MRI Scans (`MRI - Magnetic Resonance Imaging scans`): Eyinom kyerɛ nnompe no tebea kɔ akyiri sen X-ray.

Dɛn ne ayaresa ahorow a wɔde sa (OFC)?

Okay, afei momma yɛnka ayaresa a wɔde sa `(Osteitis Fibrosa Cystica)` ho asɛm. Ayaresa no gyina `(Hyperparathyroidism)` a ɛde `(OFC)` no bae ne sɛnea emu yɛ den so.

• Sɛ hyperparathyroidism titiriw no fi:
• Mpɛn pii no, sɛ nea ɛde `(OFC)` tebea yi ba ne `(Parathyroid)` ntini no dwumadi a ɛnteɛ (te sɛ akisikuru) a, ayaresa a wɔtaa de di dwuma ne sɛ wɔbɛyɛ oprehyɛn ayi ntini no anaa ntini no fã bi (`Parathyroidectomy`) . Saa oprehyɛn yi betumi agyae nnompe no a ɛyɛ teateaa na ama nnompe a asɛe dedaw no bi asan aba (`remineralization`). Mpɛn pii no, yɛwɔ `(Parathyroid)` ntini anan. Enti, sɛ woyi ntini a ɛwɔ ɔhaw no fi hɔ a, ntini a aka no betumi ayɛ `(PTH)` hormone a nipadua no hia no.

• Wɔn a wontumi nyɛ wɔn oprehyɛn anaasɛ wɔwɔ hyperparathyroidism a ɛto so abien no fam no:
• Nea ɛde ba no a wɔbɛsa: Sɛ nhwɛso no, sɛ nea ɛde ba ne vitamin D a wonnya a, wɔma vitamin D a wɔde ka ho. Sɛ ɛyɛ asaabo mu yare a, wɔsa no sɛnea ɛfata.
• Calcimimetics: Nnuru yi suasua calcium a ɛwɔ wo mogya mu no. Wɔ "daadaa" wo parathyroid gland no ma ɛyɛ PTH kakraa bi. Cinacalcet yɛ nnuru a ɛte saa no mu biako.
• Bisphosphonates: Saa nnuru yi yɛ adwuma denam nnompe a ɛyera a ɛbrɛ ase no so. Wɔtaa kyerɛw ma nnipa a wɔwɔ nnompe mu yare. Nanso, wobetumi aboa nnipa a wɔwɔ OFC nso wɔ bere tiaa bi mu, titiriw sɛ wɔbɛhyɛ nnompe mu den ansa na wɔayɛ wɔn oprehyɛn.
• Vitamin D ne calcium a wɔde ma: Wɔde eyinom ma sɛnea ɛho hia. Nanso, sɛ mogya mu calcium dɔɔso a, wɔmfa calcium nka ho mma.

Dɛn ne anidaso a ɛwɔ hɔ ma (OFC) gyinabea?

Dɛn ne anidasoɔ a ɛwɔ saa `(OFC)` tebea yi ho? Nokwarem no, sɛ wɔhwɛ so yiye na wɔsa yare a, wobetumi anya nneɛma pa . Ayaresa betumi agyae nnompe no a ɛyɛ teateaa na ahyɛ nnompe no den (`remineralize`). Nnompe a abubu betumi asa na ɛyaw no so atew. Nanso, sɛ nnompe no asɛe kɛse a, ebia ɛrennya ahoɔden koraa.

So wobetumi asiw (OFC) ano?

So ebetumi aba sɛ wobesiw tebea yi `(Osteitis Fibrosa Cystica)` a ɛbɛba no ano? Yiw, ɛde besi baabi no, ebetumi aba. Ade titiriw ne sɛ wubehu na woasa tebea `(Hyperparathyroidism)` no ntɛm.

• Ɛho hia yiye sɛ woyɛ mogya mu nhwehwɛmu daa , titiriw sɛ wowɔ nneɛma a ɛde asiane ba te sɛ asaabo mu yare a. Eyi bɛboa ma woahu nsakrae biara a ɛba wo mogya mu calcium ne PTH dodow mu ansa na asɛe ade kɛse.
• Afei nso, wo ne wo duruyɛfo nkasa na kɔ so nya calcium ne vitamin D dodow pa.Yɛ nea ɛsɛ sɛ woyɛ. Sɛ nhwɛso no, sɛ wote ɔmantam bi a owia hann kakraa bi na ɛwɔ hɔ wɔ awɔw bere mu a, ebia ebehia sɛ wonom vitamin D a wɔde ma. Wo duruyɛfo nso bɛkyerɛ wo sɛnea wubenya aduannuru a wuhia afi nnuan a wudi no mu.

Kae sɛ, dodow a wohu tebea `(Hyperparathyroidism)` no ntɛm na wɔsa no, dodow no ara na ɛnyɛ den sɛ ebenya `(Osteitis Fibrosa Cystica)`.

Bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn?

Sɛ wo dompe mu yɛ wo yaw, wo ho yɛ wo yaw, anaa wo dompe bi a ɛte sɛ nea ebebubu , kɔ oduruyɛfo nkyɛn ntɛm ara. Afei nso, sɛ wowɔ hyperparathyroidism ho sɛnkyerɛnne ahorow a edi kan (te sɛ ɔbrɛ, akisikuru, ne nsu a wɔtaa tow) a madi kan aka ho asɛm no bi a, ka ho asɛm kyerɛ wo duruyɛfo . Sɛ wowɔ hyperparathyroidism dedaw a, ɛyɛ papa sɛ wobɛma wɔayɛ wo mogya mu nhwehwɛmu daa de ahwɛ sɛnea wo calcium ne PTH dodow te, sɛnea wo duruyɛfo kamfo kyerɛ no.

Nsɛm bɛn na ɛsɛ sɛ mibisa me duruyɛfo?

Sɛ wohu sɛ wowɔ `(Osteitis Fibrosa Cystica)` a, ɛbɛyɛ papa sɛ wubebisa wo duruyɛfo nsɛm yi:

• Me tebea no nye dɛn?
• Ayaresa ahorow bɛn na mewɔ? Dɛn ne mfaso ne ɔhaw ahorow a ɛwɔ emu biara so?
• So ɛnyɛ hwee sɛ mɛnom nnuru a wɔde ka aduan ho? Ɔkwan bɛn so?
• So ebehia sɛ wɔyɛ me oprehyɛn? Sɛ saa a, dɛn na metumi ahwɛ kwan wɔ ɛno akyi?
• Nsakrae bɛn na metumi ayɛ wɔ aduan mu a ɛbɛboa me?
• Saa tebea yi bɛka me da biara da asetra dɛn?

Nea etwa to no, nsɛntitiriw kakraa bi

Enti, ɛsɛ sɛ meka eyi kyerɛ wo. Nnompe a ɛyɛ mmerɛw ne ɛyaw betumi anya yɛn da biara da asetra so nkɛntɛnso kɛse. Sɛ wo nnompe bubu ntɛmntɛm a, ebia wobɛte nka mpo sɛ wubehu dwumadi ahorow bi. Sɛ wowɔ sɛnkyerɛnne te sɛ ɔbrɛ, mmerɛwyɛ, akisikuru, ne wo taa tow nsu a, ebetumi ayɛ ``Hyperparathyroidism`` anaa ne haw ``OFC``.

Sɛ wowɔ saa sɛnkyerɛnne yi bi a, yɛsrɛ wo kɔ oduruyɛfo nkyɛn a ɛnkyɛ. Dodow a wuhu yare no ntɛm na wosa no, dodow no ara na wubetumi asɛe wo nnompe pii. W’akwahosan ho hia wo paa. Enti hwɛ so yiye.

` Nnompe mu yare Fibrosa Cystica, OFC, Nnompe mu Yare, Parathyroid, PTH Hormone, Hyperparathyroidism, Nnompe mu Ɛyaw