So wɔakyerɛw wo Pazopanib? Momma yɛnka aduru yi ho asɛm nkɔ akyiri!

So oduruyɛfo bi akyerɛw wo aduru bi a wɔfrɛ no Pazopanib? Anaasɛ obi a wunim no renom saa aduru yi? Ɛyɛ ade a ɛfata sɛ wobɛte ehu nka kakra na wopɛ sɛ wuhu aduru foforo bi, titiriw wɔ tebea a emu yɛ den te sɛ kokoram ho. Nsɛmmisa ba w’adwenem, ɛnte saa? "So eyi bɛsa yare no?", "Dɛn ne nea efi mu ba?" Nneɛma a ɛtete saa. Enti ɛnnɛ, momma yɛnka aduru ko a Pazopanib yɛ, sɛnea wɔde di dwuma, ne nneɛma a ɛsɛ sɛ yɛhwɛ yiye wɔ ho, wɔ ɔkwan a ɛyɛ mmerɛw yiye a wubetumi ate ase so.

Dɛn ne aduru yi?

Sɛ yɛbɛka no tiawa a, Pazopanib yɛ aduru a ɛboa ma kokoram nkwammoaa nyin . Ɛka nnuru bi a wɔfrɛ no biologic drugs ho . Eyi kyerɛ sɛ wɔde nneɛma a wonya fi nkwammoaa a nkwa wom mu na ɛyɛ. Wɔnte sɛ nnuru a wɔde di dwuma daa, nanso ɛyɛ nea ɛyɛ den kakra.

Wɔde pazopanib di dwuma titiriw ma:

• Asaabo mu kokoram
• Kokoram bi a ɛba ntini a ɛyɛ mmerɛw a wɔfrɛ no sarcoma mu

Nanso, ɛtɔ mmere bi a wo duruyɛfo betumi akyerɛw saa aduru yi ama wo wɔ tebea afoforo ho, enti sɛ wowɔ nsɛmmisa bi a, ɛbɛyɛ papa sɛ wubebisa wo duruyɛfo anaa nnuruyɛfo.

Wɔtaa hu saa aduru yi wɔ gua so wɔ din Votrient ase.

Nneɛma bɛn na ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woanom aduru no?

Ansa na wubefi ase de Pazopanib adi dwuma no, ɛho hia yiye sɛ woka w’ayaresa tebea nyinaa kyerɛ wo duruyɛfo . Nea enti a ɛte saa ne sɛ nnipa a wɔwɔ ayaresa tebea horow bi hia ahwɛyiye soronko bere a wɔrenom aduru yi. Hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo sɛ wowɔ tebea horow a edidi so yi mu biara a:

• Mogya a ɛretu ho haw: So wowɔ ɔhaw bi a wuntumi nnyae mogyatɔw ntɛm? Anaasɛ wo hwene mu mogya taa tu? Sɛ saa a, ɛsɛ sɛ woka kyerɛ yɛn, efisɛ ɛtɔ mmere bi a aduru yi tumi ma mogya tu no yɛ kɛse.
• Sɛ wɔayɛ wo oprehyɛn nnansa yi ara (wɔ nnafua 7 ntam) anaasɛ wɔayɛ nhyehyɛe sɛ wɔbɛyɛ wo oprehyɛn daakye a: Saa nsɛm yi ho hia efisɛ saa aduru yi betumi aka kuru a ɛsa.
• Koma mu yare: Sɛ wowɔ komayare a, ɛsɛ sɛ wo duruyɛfo hu.
• Mogya mmoroso: Saa aduru yi betumi aka mogya mmoroso.
• Abakɔsɛm a ɛfa koma a ɛbɔ a ɛnteɛ ho: Sɛ woanya koma a ɛbɔ a ɛnteɛ pɛn a, ka kyerɛ yɛn.
• Sɛ woanya akisikuru a: Ɛsɛ sɛ nnipa a wɔadi kan anya akisikuru no ka eyi ho asɛm kyerɛ wɔn duruyɛfo.
• Mmɛn mu yare: Sɛ wowɔ mmerɛbo mu haw a, ebia ɛho behia sɛ wɔsesa nnuru dodow a wode di dwuma no anaasɛ wɔyɛ nhwehwɛmu titiriw bi.
• Ahurututu anaa ɔhome mu nyarewa, sɛ nhwɛso no, ayamtu:Ka wɔn a wɔwɔ ɔhome mu haw no amanneɛ.
• Sɛ protein wɔ wo nsu mu a: Eyi betumi ayɛ asaabo mu haw ho sɛnkyerɛnne.
• Thyroid haw ahorow: Thyroid hormone dodow betumi aka.
• Sɛ woanya Pazopanib anaa nnuru foforo biara, nnuan, nnuru a wɔde yɛ nneɛma, anaa nneɛma a wɔde siw ano ho adwene a ɛyɛ soronko anaasɛ wo ho yɛ wo hyew a: Sɛ wo ho yɛ wo hyew wɔ biribiara ho a, ɛho hia yiye sɛ woka kyerɛ wo duruyɛfo.
• Sɛ woanyinsɛn anaasɛ worebɔ mmɔden sɛ wubenyinsɛn a: Eyi ho hia yiye . Saa aduru yi mfata mmaa a wɔyem.
• Sɛ worema nufu a: Saa aduru yi nso mfata mma ɛnanom a wɔma wɔn nufu.

Ɛnyɛ saa nneɛma yi nko, na mmom ka akwahosan ho haw foforo biara a wowɔ ho asɛm kyerɛ wo duruyɛfo . Biribi ketewaa bi mpo betumi ayɛ nea ɛho hia.

Ɔkwan bɛn so na ɛsɛ sɛ mede saa aduru yi di dwuma?

Ɛho hia paa sɛ wode saa aduru yi di dwuma yiye. Ɛsɛ sɛ wofa no sɛnea wo duruyɛfo ka kyerɛ wo no pɛpɛɛpɛ, wɔ dodow a ɛfata mu, wɔ bere a ɛfata mu.

• Ɛsɛ sɛ wɔnom saa aduru yi ne nsu kuruwa biako.
• Di akwankyerɛ a ɛwɔ nnuru a wɔakyerɛw ama wo a wo duruyɛfo de ama wo no akyi pɛpɛɛpɛ.
• Mmu, nbubu, anaa nwe tablet no. Mene no nyinaa.
• Ɛsɛ sɛ wɔnom saa aduru yi bere a yafunu da mpan . Ɛne sɛ, anyɛ yiye koraa no, dɔnhwerew biako ansa na wɔadidi anaa nnɔnhwerew abien wɔ adidi akyi . Mfa saa aduru yi nka aduan ho.
• Mfa saa aduru yi nka borɔdɔma nsu ho. Grapefruit nsu betumi asesa ɔkwan a nipadua no fa so twetwe aduru yi.
• Nom aduru no wɔ bere a ɛfata mu, sɛnea wo duruyɛfo ka kyerɛ wo no pɛpɛɛpɛ. Mfa dodow a wɔakyerɛw ato hɔ no nnwe.
• Nnyae aduru no nom a wunnya wo duruyɛfo afotu. Sɛ wo ho tɔ wo mpo a, kɔ so nom aduru no kosi sɛ wo duruyɛfo bɛka akyerɛ wo.

Sɛ wunya saa aduru yi fi nnurutɔnbea a, wɔbɛma wo nhomawa titiriw bi (MedGuide) . Nsɛm a ɛho hia paa wɔ aduru yi ho. Mma wo werɛ mmfi sɛ wobɛkenkan saa nhomawa no yiye bere biara a wobɛsan ahyɛ wo nnuru no mu anaasɛ wobɛsan ahyɛ mu ma .

Sɛ wode saa aduru yi ma mmofra a: Wo ne wo mmofra oduruyɛfo nkasa fa aduru yi a wode bɛma mmofra ho. Ebia ɛho behia sɛ wɔhwɛ yiye titiriw.

Dodow a ɛboro so: Sɛ wususuw sɛ woanom aduru yi dodo a, frɛ beae a wɔhwɛ awuduru so anaa baabi a wɔhwɛ wɔn a wɔwɔ ayaresa a egye ntɛmpɛ ntɛm ara.

Nea ɛho hia: Saa aduru yi yɛ ma wo nkutoo. Mfa nnkyerɛ afoforo. Esiane sɛ ɛyɛ adwuma ma wo nti, ebia ɛrenyɛ adwuma mma afoforo.

Sɛ wopa nnuru dodow bi a, dɛn na ɛsɛ sɛ woyɛ?

Ɛtɔ da a, wo werɛ fi sɛ wobɛnom w’aduru, ɛnte saa? Sɛ ɛba saa a, mma ɛnhaw wo.

• Fa w’aduru no bere a woakae ara pɛ.
• Nanso, sɛ ennu nnɔnhwerew 12 kosi sɛ wobɛnom dodow a edi hɔ no a, nnom dodow a woayera no. Fa dodow a edi hɔ no ara wɔ bere a wɔahyɛ da ayɛ no mu.
• Mfa nnuru mmɔho abien anaa nea ɛboro so da. Saa a wobɛyɛ no betumi de ɔhaw ahorow aba.

Nneɛma foforo bɛn na ebetumi ne aduru yi adi nkitaho?

Pazopanib betumi ne nnuru afoforo bi adi nkitaho. Eyi kyerɛ sɛ sɛ wɔka bom a, aduru biako a etu mpɔn no betumi asesa anaasɛ nea efi mu ba no betumi ayɛ kɛse.

Mfa Pazopanib nka nnuru a edidi so yi ho:

• Cisapride na ɔkyerɛwee
• Dronedarone a wɔfrɛ no Dronedarone
• Fluconazole a wɔde ma
• Pimozide a wɔde yɛ nnuru
• Posaconazole a wɔde ma
• Saquinavir a wɔde di dwuma
• Thioridazine a wɔde ma

Saa aduru yi nso betumi ne nnuru a edidi so yi adi nkitaho:

• Nnuru bi a ekum ɔyare mmoawa, sɛ nhwɛso no, clarithromycin.
• Nnuru bi a wɔde sa nyarewa a mmoawa de ba te sɛ HIV anaa hepatitis.
• Nnuru bi a wɔde sa fungal yare, sɛ nhwɛso no ketoconazole anaa itraconazole.
• Wɔde nnuru bi ma de siw akisikuru ano, sɛ nhwɛso no, carbamazepine, phenobarbital, ne phenytoin.
• Nnuru afoforo a ɛma koma bɔ ntɛmntɛm (ɛma QT ntam kwan kyɛ).
• Nnuru a esiw yafunu mu acid ano, te sɛ lansoprazole, omeprazole, anaa pantoprazole.

Saa list yi nka nkitahodi ahorow nyinaa ho. Enti, ka nnuru a worenom (wɔakyerɛw ama wo, a wontɔn, nhabannuru, vitamin, anaa aduannuru) nyinaa ho asɛm kyerɛ wo duruyɛfo. Afei nso, sɛ wonom sigaret, wonom nsa, anaa wode nnubɔne foforo di dwuma a, ka kyerɛ wo duruyɛfo . Saa nneɛma yi betumi ne w’aduru no adi nkitaho.

Nneɛma bɛn na ɛsɛ sɛ yɛhwɛ yiye wɔ ho bere a yɛrenom nnuru no?

Ɛsɛ sɛ wohwɛ w’akwahosan so titiriw bere a worenom saa aduru yi no.

• Kɔ wo duruyɛfo nkyɛn daa: Kɔhwɛ sɛnea wo duruyɛfo ka kyerɛ wo no. Ebia ɛho behia nso sɛ woma wɔyɛ mogya adwuma bere a worenom aduru yi.
• Hwɛ sɛnea yare no ho sɛnkyerɛnne bi te: Sɛ wunya yare no ho sɛnkyerɛnne te sɛ atiridiinini, atiridiinini, menewam yaw, anaa hwene a ɛretu a, ka kyerɛ wo duruyɛfo ntɛm ara. Mma nnyɛ wo ho aduru. Saa aduru yi betumi atew tumi a wo nipadua no tumi ko tia nyarewa no so. Enti bɔ mmɔden sɛ wobɛtwe wo ho afi nnipa a wɔyare ho.
• Asiane a ɛwɔ hɔ sɛ mogya bɛtu anaa akuru:Saa aduru yi betumi ama nnipa binom apirapira anaa mogya atɔ wɔn ntɛmntɛm. Sɛ wuhu mogya bi a ɛyɛ soronko (sɛ nhwɛso no, efi wo hwene, wo hwene, anaa wo nsu mu) a, ka kyerɛ wo duruyɛfo .
• Hwɛ yiye wɔ nyinsɛn ne awo ho:
• Nnyinsɛn bere a worenom aduru yi ne anyɛ yiye koraa no adapɛn 2 bere a woagyae aduru no akyi. Ɛsɛ sɛ mmea bɔ wɔn duruyɛfo amanneɛ sɛ wɔreyɛ nhyehyɛe anyinsɛn anaasɛ wosusuw sɛ wɔanyinsɛn a.
• Ɛsɛ sɛ mmarima kwati sɛ wɔbɛwo abofra bere a wɔrenom saa aduru yi ne anyɛ yiye koraa no adapɛn 2 bere a wɔagyae aduru no akyi.
• Ebetumi aba sɛ ɛde ɔhaw a emu yɛ den bɛba akokoaa a ɔhyɛ yafunu mu no so. Bisa wo duruyɛfo anaa nnuruyɛfo ma ɔmma wo eyi ho nsɛm pii.
• Mma wo ba no nufu bere a worenom saa aduru yi ne adapɛn 2 bere a woagyae aduru no akyi.
• Nkɛntɛnso a enya wɔ awo so: Saa aduru yi betumi aka sɛnea wubetumi awo mma. Sɛ wowɔ eyi ho dadwen bi a, wo ne wo duruyɛfo nkasa.
• Ansa na wobɛyɛ oprehyɛn: Sɛ wɔreyɛ wo oprehyɛn biara a, wo ne wo duruyɛfo nkasa ansa na woayɛ saa na nya kwan. Ebia saa aduru yi bɛma akuru a wɔde yɛ oprehyɛn no sa akyɛ. Ɛsɛ sɛ wugyae saa aduru yi nom dapɛn biako ansa na woayɛ wo oprehyɛn. Sɛ woyɛ oprehyɛn wie a, anyɛ yiye koraa no twɛn adapɛn abien na twɛn kosi sɛ kuru no bɛsa koraa ansa na woafi aduru yi ase bio. Sɛ wowɔ nsɛmmisa bi fa eyi ho a, wo ne wo duruyɛfo nkasa.

Dɛn ne aduru yi mu nsunsuanso bɔne a ebetumi afi mu aba?

Te sɛ aduru biara no, Pazopanib betumi de ɔhaw ahorow aba nnipa binom so. Ɛnyɛ obiara na onya wɔn. Nanso, ɛho hia sɛ wuhu nea ebetumi afi mu aba no.

Nneɛma bɔne a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ntɛm ara:

Sɛ wuhu saa sɛnkyerɛnne ahorow yi bi a, ka kyerɛ wo duruyɛfo anaa akwahosan ho ɔyaresafo ntɛm ara sɛnea wubetumi:

• Nneɛma a ɛma obi ho yɛ no hyew: Honam ani akisikuru, ɛyaw anaa akisikuru, anim, anofafa anaa tɛkrɛma a ɛho ahonhon.
• Ɔhome mu haw ahorow.
• Nsakrae a ɛba wɔ anisoadehu mu.
• Koko mu yaw.
• Honam ani a ɛyɛ kɔkɔɔ, ɛyɛ kurukuruwa, ɛho tew, mogya tu, anaa ɛho ahonhon wɔ nsateaa ne nan ase.
• Akisikuru a ɛma obi ho kyere no.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ mogya retu: Mogya a ɛwɔ nsu mu, anaa nsu a ɛyɛ tuntum a wɔde tarry ayɛ; Nsu a ɛyɛ kɔkɔɔ anaa bruu tuntum; Nneɛma a ne kɔla yɛ bruu te sɛ kɔfe a wɔayam anaa mogya a ɛwɔ nnompe mu a wɔfe; Nsõ kɔkɔɔ a ɛwɔ honam ani; Mogya anaa akuru a ɛyɛ soronko a efi aniwa, anom, anaa hwene mu.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ mogya ayɛ no yaw: Koko mu yaw; Ɔhome a ɛyɛ den; Nan mu yaw, ɛho ahonhon, anaa ɔhyew.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ koma ayɛ adwuma:Ɔhome a ɛyɛ den; koma a ɛbɔ ntɛmntɛm a ɛnyɛ nea ɛkɔ so daa; mu duru a ɛkɔ soro mpofirim; nansoaa, nan anaa nsa a ɛho ahonhon; te nka sɛ wayɛ mmerɛw anaasɛ wabrɛ wɔ ɔkwan soronko so.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya ɔyare no: atiridiinini; awɔw a ɛyɛ nwini; ɛwa; menemkuro; ɛyaw anaasɛ ɛyɛ den sɛ wobɛtow nsu.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ mmerɛbo apira: Nsu a ɛyɛ kɔkɔɔ anaa bruu tuntum; sɛ obi te nka sɛ ne ho nyɛ no den anaasɛ ne ho ayɛ no hyew; nsu a ɛyɛ mmerɛw; aduan ho akɔnnɔ a ɛyera; abofono; ɛyaw a ɛba yafunu nifa a ɛwɔ soro no mu; mmerɛwyɛ anaa ɔbrɛ a ɛyɛ soronko; honam ani anaa aniwa a ɛyɛ kɔkɔɔ.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya ɔyare a ɛma obi hwe ase: Anisoadehu sesa; kesereneeyɛ; kasa anaa ntease a ɛyɛ den; tiyɛ a emu yɛ den; anim, abasa, anaa nan a ɛyɛ mmerɛw anaa mmerɛwyɛ mpofirim; ɛyɛ den sɛ wobɛnantew; adwenemhaw a ɛma obi ho kyere no; kari pɛ a wɔhwere.
• Tumor Lysis Syndrome Nsɛnkyerɛnne: Akisikuru, ɔfe, akisikuru, koma a ɛbɔ a ɛnteɛ, ɔbrɛ, akisikuru, adwene a ɛyɛ basaa, ntini a ɛtwetwe anaa ɛyaw, nsu a ɛba no so tew.

Nneɛma bɔne a ɛho nhia sɛ woka ho asɛm kyerɛ wo duruyɛfo , nanso sɛ ɛkɔ so anaasɛ ɛhaw wo a, ɛsɛ sɛ wobɔ ho amanneɛ:

Sɛ eyinom nyɛ aniberesɛm kɛse mpo a, sɛ ɛkɔ so anaasɛ ɛhaw wo a, ka kyerɛ wo duruyɛfo .

• Nwi kɔla sesa.
• Nsakrae a ɛba wɔ dɛ mu.
• Ayamtuo.
• Aduan no nyɛ dɛ.
• Honam ani kɔla a ɛsakra.
• Mu duru a ɛso tew.

Ebia nneɛma bɔne a efi mu ba nyinaa nka saa nsɛm a wɔahyehyɛ yi ho. Sɛ wuhu biribi a ɛyɛ soronko a, wo ne wo duruyɛfo nkasa. Wubetumi nso abɔ amanneɛ akyerɛ FDA wɔ 1-800-FDA-1088.

Ɔkwan bɛn so na ɛsɛ sɛ wode w’aduru sie?

• Fa sie baabi a mmofra ntumi nkɔ.
• Fa sie wɔ dan mu hyew (a ɛwɔ digrii Celsius 15 kosi 30 / digrii Fahrenheit 59 ne 86 ntam).
• Tow nnuru a ne bere atwam gu.

Nea yesua fii eyi mu (Take-Home Message) .

Pazopanib yɛ aduru a ɛho hia a ɛboa ma wɔko tia kokoram. Ɛho hia sɛ wuhu saa aduru yi na wudi wo duruyɛfo akwankyerɛ akyi pɛpɛɛpɛ.

Kae sɛ, sɛ wowɔ nsɛmmisa anaa nsɛm bi a ɛhaw wo a, nsuro sɛ wubebisa wo duruyɛfo anaa nnuruyɛfo. Wo ne wo duruyɛfo no na mobom sisi w’akwahosan ho gyinae. Enti ka biribiara ho asɛm pefee.

Yɛwɔ anidaso sɛ saa asɛm yi ama woate aduru Pazopanib no ase yiye. Yɛpɛ sɛ wo ho tɔ wo ntɛm!

` Pazopanib, Pazopanib, kokoram aduru, asaabo mu kokoram, sarcoma, nnuru a ɛde ba, kokoram ayaresa