So wɔakyerɛw wo Rucaparib? Momma yɛnka eyi ho asɛm nkɔ akyiri!

Ɛyɛ ade a ɛfata sɛ wobɛte adesoa kɛse nka bere a wuhu sɛ wowɔ kokoram no. Nanso sɛ wo duruyɛfo ka kyerɛ wo sɛ fi ase nom aduru bi a wɔfrɛ no ‘Rucaparib’ a, ɛyɛ ade a ɛfata nso sɛ wubenya nsɛmmisa pii wɔ ho. Enti, ɛnnɛ yɛbɛka Rucaparib nnuru yi ho asɛm, nea saa aduru yi yɛ, sɛnea ɛyɛ adwuma, ne nea ɛsɛ sɛ wohwɛ yiye wɔ ho, ne nyinaa wɔ ɔkwan a ɛyɛ mmerɛw yiye a wubetumi ate ase so.

Dɛn ankasa ne aduru yi a wɔfrɛ no Rucaparib?

Sɛ yɛbɛka no tiawa a, Rucaparib yɛ aduru titiriw bi a ɛde n’ani si protein ahorow bi a ɛwɔ kokoram nkwammoaa mu so na esiw wɔn nyin ano . Ɔkwan foforo so no, ɛpaw sɛ ɛtow hyɛ kokoram nkwammoaa so . Wɔde saa aduru yi sa awotwaa mu kokoram ne prostate kokoram ahorow bi titiriw . Ɛtɔ da bi a wobetumi de adi dwuma ama kokoram ahorow afoforo, na wo duruyɛfo bɛka ho asɛm akyerɛ wo.

Sɛ wotɔ saa aduru yi fi nnurutɔnbea a, ebia wobetumi anya bi wɔ din ``Rubraca`` ase. Nanso, ebia wobetumi anya bi wɔ din ahorow mu wɔ aman ne nnwumakuw ahorow mu. Enti nsusuw edin no ho kɛkɛ, ɛsɛ sɛ wo nso wohwɛ sɛ aduru a wo duruyɛfo kyerɛw maa wo no yɛ Rucaparib anaa.

Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi saa aduru yi ase

Ansa na wobɛhyɛ aseɛ anom Rucaparib no, ɛho hia sɛ woka w’aduruyɛ ho abakɔsɛm kyerɛ wo duruyɛfoɔ sɛdeɛ ɛbɛyɛ a ɔbɛtumi asi gyinaeɛ sɛ saa aduru yi fata wo anaa sɛ ɛhia sɛ woyɛ ahwɛyie soronko biara. Hwɛ hu sɛ wobɛka:

• Sɛ woadi kan anya mogya mu nyarewa a , sɛ nhwɛso no , myelodysplastic syndrome anaa mogya mu kokoram .
• Sɛ mogya mu nneɛma a ɛwɔ wo mu no sua a . Ɛno kyerɛ sɛ wo mogya mu nkwammoaa fitaa, mogya mu nkwammoaa kɔkɔɔ, anaa mogya mu nkwammoaa kɔkɔɔ sua .
• Sɛ woanya aduru yi ho adwenemhaw a , Rucaparib, anaa aduru foforo biara, aduan, ade a wɔde yɛ ade, anaa nea wɔde siw ano.
• Sɛ woanyinsɛn anaasɛ wowɔ anidaso sɛ wubenyinsɛn a .
• Sɛ woyɛ ɛna a ɔma nufu a .

Ɛnyɛ saa nneɛma yi nko, na mmom ɛho hia paa sɛ wobɛka nyarewa foforo biara a wowɔ ne nnuru a worenom (ɛno kyerɛ sɛ ɛnyɛ nea nnuruyɛfo akyerɛw ama wo nko, na mmom nea wotɔ wɔ nnurutɔnbea nso, vitamin ahorow, ne nhabannuru mpo).

Enti, ɔkwan bɛn so ankasa na ɛsɛ sɛ wode saa aduru yi di dwuma?

Saa aduru yi ba sɛ aduru a wɔde di dwuma wɔ ano . Ɛho hia sɛ wobɛnom da biara, bere koro no ara a wo duruyɛfo anaa nnuruyɛfo ka kyerɛ wo no. Di akwankyerɛ a ɛwɔ aduru no ho krataa so no akyi pɛpɛɛpɛ.

• PillMma nmmubu, ntwitwa, anaa nwe. Fa nsu mene ne nyinaa.
• Wobetumi anom eyi a wɔde aduan aka ho anaasɛ wɔmfa nni dwuma . Nanso, sɛ wote nka sɛ wo yafunu ayɛ wo yaw a, ɛbɛyɛ papa sɛ wode ka aduan bi ho.
• Ɛsɛ sɛ wokɔ so de saa aduru yi di dwuma kosi sɛ wo duruyɛfo bɛka akyerɛ wo sɛ gyae . Sɛ wo ho tɔ wo mpo a, nnyae sɛ wobɛnom mpofirim a wo duruyɛfo nka ho afotu. Saa a wobɛyɛ no betumi ama wo tebea no asɛe.

Sɛ wode saa aduru yi rema mmofra a , ɛsɛ sɛ wo ne wo duruyɛfo kasa fa ho na wunya afotu titiriw. Esiane sɛ mmofra nipadua renyin nti, ɔkwan a wɔfa so de aduru no ma wɔn no betumi asesa.

Kae sɛ, sɛ wususuw sɛ woanom aduru yi dodo a , mma wo ho nnyɛ wo hu, frɛ ayaresabea dan a wɔhwɛ wɔn a wɔwɔ yare a egye ntɛmpɛ anaa beae a wɔhwɛ awuduru so a ɛbɛn wo no ntɛm ara. Ɛno ho hia paa.

Ade a ɛho hia sen biara a ɛsɛ sɛ wokae: Wɔakyerɛw saa aduru yi ama wo nkutoo . Mfa mma obi foforo biara esiane biribi nti, sɛ mpo saa onipa no wɔ yare no ho sɛnkyerɛnne koro no ara te sɛ wo a.

Sɛ wopa nnuru dodow bi a, dɛn na woyɛ?

Mma ɛnhaw wo, nneɛma betumi asi. Sɛ wopa dodow bi a, twa dose a woayera no so koraa . Fa wo dodow a edi hɔ no wɔ bere a wotaa fa no mu . Mfa nnuru mmɔho abien da mfa nsiesie dodow a woayera no. Saa a wɔbɛyɛ no betumi ama asiane a ɛwɔ hɔ sɛ wobenya ɔhaw ahorow no ayɛ kɛse.

Nneɛma foforo bɛn na ebetumi ne aduru yi adi nkitaho?

Rucaparib betumi ne nnuru ne nnuan afoforo a wonom no adi nkitaho . Eyi kyerɛ sɛ sɛ wɔka bom a, ebetumi aka ɔkwan a rucaparib fa so yɛ adwuma anaa ɔkwan a nnuru foforo no fa so yɛ adwuma. Eyi betumi ama asiane a ɛwɔ hɔ sɛ obenya nsunsuanso bɔne no ayɛ kɛse anaasɛ ɛbɛma aduru no a etu mpɔn no so atew. Enti, ɛho hia sɛ woka nneɛma a edidi so yi mu biara kyerɛ wo duruyɛfo:

• Nsã a caffeine wom (te sɛ tii, kɔfe, chocolate ahorow bi, ne anonne a ɛyɛ dɛ bi).
• Digoxin (eyi yɛ aduru a wɔtaa de ma komayare).
• Midazolam (aduru a ɛtɔ mmere bi a wɔde ma ansa na wɔayɛ oprehyɛn anaa wɔayɛ nhwehwɛmu ahorow bi de atew n’adwene so).
• Warfarin (eyi yɛ aduru a wɔde ma sɛ mogya ntumi nkɔ).

Saa nsɛm a wɔahyehyɛ yi yɛ nhwɛso kakraa bi pɛ. Ka nnuru a wonom nyinaa (wɔakyerɛw ama wo, a wontɔn, nhabannuru, vitamin, ne nnuru a wɔde ka aduan ho) kyerɛ wo duruyɛfo . Afei nso, di nokware wɔ nnuru biara a wonom, wonom nsa, anaa nnubɔne afoforo ho . Eyinom nso betumi ne aduru yi adi nkitaho.

Nneɛma bɛn na ɛsɛ sɛ wohwɛ yiye wɔ ho titiriw bere a worenom aduru yi?

Sɛ wonom saa aduru yi a, woEbia wobɛte nka sɛ wo ho nyɛ wo dɛ kakra na woayare asen sɛnea wotaa yɛ no. Ɛno yɛ ade a ɛfata. Eyi te saa efisɛ saa nnuru ahorow yi a ɛko tia kokoram (ebia woate ho asɛm sɛ `chemotherapy` , a ɛno ne nea ɛyɛ) ɛnyɛ kokoram nkwammoaa nko na ebetumi aka, na mmom nkwammoaa a ɛte apɔw nso wɔ yɛn nipadua mu kodu baabi. Enti, sɛ wunya ɔhaw biara a, ka ho asɛm kyerɛ wo duruyɛfo. Nanso, nnyae aduru no nom efisɛ wote nka sɛ wo ho nyɛ wo dɛ gye sɛ wo duruyɛfo ka kyerɛ wo sɛ gyae .

• Mogya mu nhwehwɛmu : Wo duruyɛfo bɛka akyerɛ wo sɛ ma wɔnhwɛ wo mogya dodow (nkwaboaa kɔkɔɔ, nkwammoaa fitaa, mogya mu nkwammoaa kɔkɔɔ, ne nea ɛkeka ho) daa bere a worenom saa aduru yi no. Ɛho hia yiye sɛ wobɛyɛ sɔhwɛ ahorow yi wɔ bere ano na worenhuruw.
• Nyinsɛn ne awo : .
• Sɛ woyɛ ɔbaa a : Nnyinsɛn bere a worenom saa aduru yi ne asram 6 wɔ bere a woagyae aduru no akyi . Sɛ worebɔ mmɔden sɛ wubenyinsɛn, anaasɛ wususuw sɛ ebia woanyinsɛn a, ɛsɛ sɛ woka kyerɛ wo duruyɛfo ntɛm ara. Wo ne wo duruyɛfo nkasa fa ɔkwan a ɛfata a wɔfa so siw awo ano ho.
• Sɛ woyɛ ɔbarima a : Mmɔ mmɔden sɛ wobɛwo abofra bere a worenom saa aduru yi ne asram 3 bere a woagyae aduru no akyi . Fa awo ano aduru a ɛfata di dwuma wɔ saa bere yi mu. Saa aduru yi betumi apira akokoaa a ɔhyɛ yafunu mu kɛse . Bisa wo duruyɛfo ma ɔmma no eyi ho nsɛm pii.
• Nufu a wɔde ma : Mma wo ba no nufu bere a worenom aduru yi anaa adapɛn 2 bere a woagyae aduru no akyi .
• Nkwaboaa a wɔde ma : Mfa mmadwoa mma bere a worenom saa aduru yi anaasɛ asram 3 bere a woagyae aduru no akyi .
• Asiane a ɛwɔ hɔ sɛ wubenya ɔyare mmoawa : Ebia saa aduru yi bɛtew wo nipadua mu ahoɔden a ɛko tia nyarewa no so kakra . Eyi kyerɛ sɛ ebia ɛyɛ mmerɛw sɛ wobɛyare. Sɛ wunya yare no ho sɛnkyerɛnne te sɛ atiridiinini, hwene mu nsu, wo menewa mu yaw, anaa atiridii , nnyɛ wo ho aduru na nka nkyerɛ wo duruyɛfo. Bɔ mmɔden sɛ wobɛtwe wo ho afi nnipa a wɔyare ho sɛnea wubetumi biara. Ɛyɛ papa nso sɛ wobɛhyɛ anim akataso bere a worekɔ mmeae a nnipa ahyɛ hɔ ma no.
• Nnuru a wɔde kum ɛyaw : Nnom nnuru a wɔde kum ɛyaw te sɛ aspirin, acetaminophen, ibuprofen, naproxen, ne ketoprofen a wunnyaa wo duruyɛfo afotu. Saa nnuru yi tumi kata yare no ho sɛnkyerɛnne te sɛ atiridiinini so, na ɛma ɛyɛ den sɛ wobehu ɔyare mmoawa bi.
• Sɛ worehohoro wo sẽ na worehohoro w’ano a : Fa ahwɛyiye yɛ bere a wode brɔs, nhama a wɔde twitwiw sẽ, anaa nnuru a wɔde twitwiw sẽ redi dwuma no. Eyi betumi ama mogya atu anaa ɔyare mmoawa. Sɛ woreyɛ wo sẽ ayaresa biara a, ka kyerɛ wo sẽ ho oduruyɛfo sɛ worenom saa aduru yi.
• Kokoram ho asiane: Wo ne wo duruyɛfo nkasa mfa asiane a ɛwɔ hɔ sɛ wubenya kokoram ahorow bi (sɛ nhwɛso no, mogya mu kokoram) denam aduru yi a wobɛnom so no ho. Ɛtɔ mmere bi a, saa asiane no betumi ayɛ kɛse kakra. Nanso, wo duruyɛfo no de aduru yi rema wo efisɛ mfaso a ɛwɔ aduru yi so no dɔɔso sen asiane a ɛwom.
• Owia ho nkate : Ebia saa aduru yi bɛma wo honam ani ayɛ mmerɛw kɛse wɔ owia ho (photosensitivity) . Enti, to owia a wobɛbɔ no ano hye sɛnea wubetumi biara. Kwati sɛ wubepue wɔ nnɔnhwerew a ɛhɔ yɛ hyew sen biara wɔ da no mu, te sɛ anɔpa 10 kosi awia 4. Sɛ ɛsɛ sɛ wupue kɔ owia mu a, hyɛ ntade a ɛkata wo honam ani (te sɛ ntade a nsa tenten ne pantan), kyɛw, ahwehwɛ a wɔde hwɛ owia, na fa aduru a ɛbɔ wo ho ban fi owia ho a SPF yɛ 30 anaa nea ɛboro saa di dwuma . Mfa owia akanea anaa mpa/ntanning beds nni dwuma.

Enti, dɛn ne nnuru yi ho nsunsuanso bɔne a ebetumi afi mu aba?

Te sɛ aduru biara no, Rucaparib aduru betumi de ɔhaw ahorow aba nnipa binom so. Nanso, ɛnyɛ obiara na onya bi. Ebia nnipa binom benya nsunsuanso nketenkete nkutoo. Ade a ɛho hia sen biara ne sɛ sɛ wuhu biribi a ɛyɛ soronko a, wobɛka akyerɛ wo duruyɛfo.

Nneɛma bɔne a ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo no ntɛm ara

Sɛ wuhu saa sɛnkyerɛnne ahorow yi bi a, ɛsɛ sɛ woka kyerɛ wo duruyɛfo ntɛm ara :

• Nneɛma a ɛma obi ho yɛ no hyew : honam ani akisikuru, ɛyaw, akisikuru; anim, anofafa, tɛkrɛma a ɛho ahonhon, ahome a ɛyɛ den.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya ɔyare no : atiridiinini (boro Celsius 38 / 100.4 Fahrenheit), atiridiinini, fifiri, ɔfe, menewam yaw, ɛyaw anaa ɛyɛ den sɛ wobɛtow, nipadua mu yaw.
• Nsu a wɔde kɔla yɛ hann.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ mmerɛbo apira : Nsu a ɛyɛ kɔkɔɔ anaa bruu tuntum; ɔbrɛ a wɔte nka kɛse sen sɛnea ɔtaa yɛ, atiridiinini; aduan ho akɔnnɔ a ɛyera, ɛyaw a ɛba yafunu nifa atifi; ɔbrɛ a ɛtra so; aniwa anaa honam ani a ɛyɛ kɔkɔɔ (te sɛ jaundice).
• Mogya mu nkwammoaa kɔkɔɔ a ɛba fam (nemia) ho sɛnkyerɛnne : Ɔhome a ɛyɛ tiaa; wo totɔ piti, wo te nka sɛ wo ho ayɛ wo hyew, anaasɛ ɛte sɛ nea wobɛhwe ase; ɔbrɛ a ɛtra so, honam ani a ɛyɛ mmerɛw, ne koko mu yaw.
• Akuru anaa mogya a ɛyɛ soronko : Akuru, hwene mu mogya, mogya a ɛba anom bere a worehohoro sẽ, mogya a ɛwɔ nsu mu (tuntum anaa kɔkɔɔ tuntum).

Sɛ ɛkɔ so, anaasɛ ɛhaw wo a, ɛsɛ sɛ woka nea efi mu ba no kyerɛ wo duruyɛfo .

Mpɛn pii no, saa nsunsuanso bɔne yi nyɛ aniberesɛm. Nanso, sɛ wɔkɔ so anaasɛ wɔhaw wo pii a , ka kyerɛ wo duruyɛfo sɛ:

• Te nka sɛ aduan dɛ asesa (`change in taste`).
• Ayamtim.
• Ayamtuo.
• Aduan ho akɔnnɔ a ɛyera.
• Ano mu akuru.
• Abofono.
• Skin rash ( nsensanee kɔkɔɔ nketenkete, a enni allergic sɛnkyerɛnne a yɛadi kan aka ho asɛm no).
• Yafunu mu yaw.
• Ɔfe a wɔfe.
• Ɔbrɛ a ɛtra so (a mogya a ɛtɔ kɔ nipadua mu ho sɛnkyerɛnne a yɛadi kan aka ho asɛm no nni mu).

Saa nsɛm a wɔahyehyɛ yi nka nsunsuanso bɔne a ebetumi aba nyinaa ho. Sɛ wuhyia biribi soronko bi a, wo ne wo duruyɛfo nka ho asɛm. Wubetumi nso abɔ saa nsunsuanso bɔne yi ho amanneɛ akyerɛ FDA (U.S. Aduan ne Nnuru Dwumadibea) denam frɛ a wobɛfrɛ 1-800-FDA-1088 so.

Ɔkwan bɛn so na ɛsɛ sɛ mede saa nnuru yi sie? Sɛ ɛka bi a, mɛyɛ dɛn atow agu?

Ɛsɛ sɛ wɔde saa aduru yi sie baabi a mmofra ne afieboa ntumi nkɔ hɔ . Ɛno ho hia paa.

• Fa sie wɔ dan mu hyew (a ɛyɛ digrii Celsius 20 kosi 25, anaasɛ digrii Fahrenheit 68 kosi 77 ntam). Mfa wo ho nhyɛ ɔhyew anaa nwini a ɛboro so mu. Mfa nneɛma nsie wɔ mmeae te sɛ aguaree.
• Mfa nnuru a ne bere atwam nni dwuma. Ɛsɛ sɛ wɔtow gu.

Sɛnea wɔtow nnuru a wɔmfa nni dwuma anaasɛ ne bere atwam gu:

• Ade a eye sen biara a ɛsɛ sɛ woyɛ ne sɛ wode saa nnuru yi bɛma `nnuru a wɔde san kɔ nhyehyɛe` . Wubetumi abisa wo nnurutɔnbea, ayaresabea, anaa ebia wo mpɔtam hɔ akwahosan adwumayɛbea no mmeae a ɛtete saa ho asɛm.
• Sɛ ɔkwan biara nni hɔ a wobɛfa so asan de a, hwɛ aduru no ho krataa anaa kratasin a ɛwɔ mu no mu hwɛ sɛ ɛka sɛ tow gu nwura mu anaasɛ fa gu tiafi mu anaa . Sɛ wunnim a, bisa wo duruyɛfo anaa nnuruyɛfo.
• Sɛ ɛyɛ nea asiane biara nni ho sɛ wobɛtow agu nwura mu a, yi nnuru no fi toa anaa kotoku no mu, fa fra mpataa nwura, kɔfe a wɔde adi dwuma, anaa dɔte yiye , fa gu kotoku anaa ade a wotumi to mu mu, na tow gu nwura mu. Eyi yɛ nea ɛbɛma anyɛ ɔhaw mma obi foforo anaa aboa bi.

Nea etwa to no, ade a ɛho hia sen biara a ɛsɛ sɛ yɛma ɛtra yɛn adwenem

Rucaparib yɛ aduru a ɛho hia a ɛboa ma wɔko tia kokoram. Sɛ worenom saa aduru yi a, ɛyɛ ade a ɛfata sɛ wubenya nsɛmmisa ne nneɛma a ɛhaw wo. Ade a ɛho hia sen biara ne sɛ wo ne wo duruyɛfo bɛbɔ biribiara ho nkɔmmɔ pefee . Sɛ wote nka sɛ biribi nyɛ wo dɛ, sɛ wuhu biribi foforo biara a, ɛmfa ho sɛnea ɛyɛ ketewaa no, ka ho asɛm kyerɛ wo duruyɛfo. Fa aduru no sɛnea ɔka kyerɛ wo no pɛpɛɛpɛ. Afei wubetumi anya ayaresa yi so mfaso kɛse.

Nsɛm titiriw a ɛfa aduru Rucaparib ho nkutoo na ɛwɔ asɛm yi mu. Ebia emu nsɛm no nyinaa nni mu. Sɛ wowɔ nsɛmmisa bi fa saa aduru yi ho a, wo ne wo duruyɛfo, nnuruyɛfo, anaa akwahosan ho ɔyaresafo foforo nkasa. Wobetumi ama wo nsɛm pii. Kae sɛ ɛnyɛ wo nkutoo na wowɔ hɔ, na w’aduruyɛfo kuw no wɔ hɔ bere nyinaa sɛ wɔbɛboa wo.

` Rucaparib, kokoram aduru, awotwaa mu kokoram, prostate kokoram, nea efi mu ba, kokoram ayaresa