So wo duruyɛfo akyerɛw Vorinostat ama wo anaa obi a ɔwɔ w’abusua mu? Esiane sɛ eyi yɛ aduru titiriw bi a wɔde sa kokoram nti, ebia wubenya nsemmisa, w’ani begye ho sɛ wubehu nneɛma pii, na ebia wubesuro kakra mpo. Ɛno yɛ ade a ɛfata. Nha wo ho. Wɔ asɛm yi mu no, yɛbɛka aduru yi, nea ɛyɛ, ne nea ɛsɛ sɛ wohwɛ yiye ho asɛm.
Aduru bɛn na Vorinostat yɛ?
Sɛ yɛbɛka no tiawa a, Vorinostat yɛ nnuru a wɔde sa yare . Nanso ɛnte sɛ kokoram aduru a yɛtaa nya wɔ ayaresabea a nkyene wom no. Ɛyɛ capsule a wode w’ano fa.
Wɔde saa aduru yi di dwuma titiriw de sa kokoram bi a ɛba honam ani a wɔfrɛ no cutaneous T-cell lymphoma (CTCL) . Ebia ɛbɛyɛ te sɛ nea ɛyɛ den kakra, nanso ɛyɛ kokoram bi a ɛka honam ani kɛkɛ. Mpɛn pii no, wo duruyɛfo bɛkyerɛw saa aduru yi wɔ din Zolinza ase.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi saa aduru yi ase
Ansa na wubefi saa aduru yi ase no, ɛho hia yiye sɛ wo ne wo duruyɛfo susuw w’akwahosan ho abakɔsɛm a edi mũ ho. Eyi te saa efisɛ aduruyɛ mu tebea horow bi hwehwɛ sɛ wɔhwɛ so yiye bere a wɔde aduru yi redi dwuma no. Titiriw no, hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo sɛ wowɔ:
- Sɛ wowɔ asikreyare a
- Sɛ wowɔ abakɔsɛm a ɛkyerɛ sɛ mogya atɔ wo mu a
- Sɛ wowɔ nsɛmmisa bi fa koma a ɛbɔ a ɛnteɛ ho a
- Sɛ wowɔ mmerɛbo mu yare a
- Sɛ worenom nnuru afoforo a esiw mogya a ɛtɔ anaasɛ ɛsa (te sɛ warfarin) .
- Sɛ wo ho ayɛ wo hyew wɔ Vorinostat anaa aduru foforo biara, aduan, anaa aduru a wɔde yɛ ade ho a.
- Sɛ worebɔ mmɔden sɛ wubenyinsɛn anaasɛ woanyinsɛn dedaw a
- Sɛ ɛna bi rema ne ba nufu a
Ɔkwan bɛn so na wɔde aduru no bedi dwuma yiye?
Ɔkwan a wofa so de saa aduru yi di dwuma no ho hia yiye. Sɛnea oduruyɛfo no kae no, sɛ obi nom bere a ɛfata a, ɛno ne ɔkwan a eye sen biara a wobɛfa so anya nea eye sen biara.
- Eyi yɛ capsule a ɛsɛ sɛ wɔde ka nsu kuruwa ho.
- Ɛho hia yiye sɛ wobɛnom saa aduru yi ne adidi . Eyi bɛtew asiane a ɛwɔ hɔ sɛ yafunu mu yɛ no yaw no so.
- Mma nwe, nbubu, anaa mmue capsule no da na nnom powder a ɛwɔ mu no. Ɛsɛ sɛ wɔmene capsule no nyinaa.
- Nnom nsa pii nsen nea oduruyɛfo no ka kyerɛ wo, na nnyae kosi sɛ ɔbɛka akyerɛ wo sɛ gyae.
Na sɛ menom boro so nso ɛ?
Fa no sɛ woanom nea ɛboro dodow a wɔakyerɛw ama wo no wɔ akwanhyia mu. Sɛ eyi ba a, mma wo ho nnyɛ wo hu na kɔ ayaresabea Emergency Department (ETU) a ɛbɛn wo ntɛm ara . Anyɛ saa aFrɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea hɔ na woanya afotu.
Na sɛ me werɛ fi sɛ mɛnom m’aduru nso ɛ?
Sɛ wo werɛ fi sɛ wobɛnom w’aduru a, dɛn na ɛsɛ sɛ woyɛ? Fa dodow a woayera no bere a woakae ara pɛ. Nanso, sɛ ɛkame ayɛ sɛ bere aso sɛ wobɛma wo dodow a edi hɔ no a, twa dodow a woayera no so na fa dodow a edi hɔ no wɔ bere a woahyɛ da ayɛ no mu. Mfa nnuru abien prɛko pɛ da (dose mmɔho abien).
Eyi yɛ aduru a wɔakyerɛw ama wo nkutoo. Mfa saa aduru yi mma obi foforo biara esiane biribiara nti.
Nnuru afoforo a ebia ɛne aduru yi bedi nkitaho
Vorinostat betumi de asiane aba bere a wɔde ka nnuru afoforo bi ho no. Enti, ɛho hia paa sɛ woka nnuru a worenom nyinaa (a vitamin, nhabannuru, ne nnuru a wɔde kum ɛyaw ka ho) kyerɛ wo duruyɛfo.
Ɛnsɛ sɛ wɔde nnuru a edidi so yi ka Vorinostat ho da:
* cisapride a wɔde yɛ aduru
* dronedarone a wɔde di dwuma
* pimozide a wɔde yɛ aduru
* thioridazine a wɔde ma
Nea ɛka ho no, nnuru afoforo wɔ hɔ a ebetumi ne eyi adi nkitaho. Enti sɛ worenom nnuru yi mu biara a, ka kyerɛ wo duruyɛfo:
- Nnuru ahorow bi a ekum ɔyare mmoawa: te sɛ `clarithromycin`, `erythromycin`, `levofloxacin`, `mefloquine`.
- Nnuru a wɔde sa adwenemhaw, dadwen, anaa adwenemyare afoforo.
- Nnuru a wɔde sa koma a ɛyɛ den.
- Nnuru te sɛ valproic acid (aduru a wɔde sa akisikuru ).
- Nnuru a ɛmma mogya ntumi nkɔ: te sɛ `warfarin`, `enoxaparin`, `heparin`.
- Kokoram ayaresa afoforo: te sɛ `dasatinib`, `lapatinib`.
- Nnuru afoforo a ɛka koma no bɔ (ɛma QT ntam kwan kyɛ).
Saa list yi nwie pɛyɛ. Enti ka nnuru a wonom, sɛ wonom sigaret, anaa sɛ wonom nsa nyinaa ho asɛm kyerɛ wo duruyɛfo.
Nsɛntitiriw a ɛsɛ sɛ wohwɛ yiye bere a worenom aduru no
Nneɛma kakraa bi wɔ hɔ a ɛsɛ sɛ wohwɛ so titiriw bere a worenom aduru yi.
- Mogya mu Nhwehwɛmu: Ɛho hia sɛ woyɛ mogya mu nhwehwɛmu daa sɛnea wo duruyɛfo akyerɛ wo bere a worenom aduru yi no. Eyi bɛboa ma wɔahwɛ sɛnea aduru no renya wo nipadua so nkɛntɛnso, titiriw wo potassium ne magnesium dodow ne wo mogya mu nkwammoaa.
- Nom nsu pii: Nom nsu pii da mũ no nyinaa. Ɛho hia yiye sɛ wosiw nsu a ɛho ayɛ fĩ ano. Bisa wo duruyɛfo no nsu dodow a ɛsɛ sɛ wonom da biara.
- Nnuru a wɔde hyɛ nipadua mu a wɔde ahwɛyiye:Sɛ aduru bi bubu anaasɛ powder a ɛwɔ mu no hwie gu a, mfa wo nsa nka powder no anaasɛ mma ɛnka w’ani anaa wo honam ani. Sɛ ɛba saa a, fa samina ne nsu hohoro baabi a ɛwɔ hɔ ntɛm ara. Sɛ ɛkɔ w’ani a, fa nsu hohoro mu yiye na frɛ oduruyɛfo ntɛm ara.
- Nyinsɛn ne nufu a wɔde ma: Eyi yɛ asɛm a ɛhaw adwene kɛse.
- Sɛ woyɛ ɔbea a, kwati sɛ wubenyinsɛn bere a worenom aduru yi ne anyɛ yiye koraa no asram 6 bere a woagyae aduru no akyi.
- Sɛ woyɛ ɔbarima a, nnyɛ abofra agya bere a worenom saa aduru yi ne anyɛ yiye koraa no asram 3 bere a woagyae aduru no akyi.
- Saa aduru yi betumi apira akokoaa a ɔhyɛ yafunu mu kɛse . Bisa wo duruyɛfo ma ɔmma no eyi ho nsɛm pii.
- Sɛ woyɛ ɛna a woma nufu a, mma wo ba no nufu bere a worenom aduru yi ne anyɛ yiye koraa no dapɛn biako bere a woagyae no.
- Awo: Ebia aduru yi bɛka w’awo. Sɛ wowɔ eyi ho dadwen bi a, wo ne wo duruyɛfo nkasa ansa na woafi ayaresa ase.
Nsunsuanso bɔne a ebetumi aba esiane nnuru nti
Te sɛ aduru biara no, Vorinostat betumi de ɔhaw ahorow aba. Ebinom yɛ aniberesɛm, na ebinom nso yɛ odwo. Ade a ɛho hia sen biara ne sɛ wubehu saa sɛnkyerɛnne ahorow yi na sɛ wuhu bi a, ka kyerɛ wo duruyɛfo ntɛm ara sɛnea wubetumi.
| Nsunsuanso bɔne no su | Esu |
|---|---|
| Nsɛnkyerɛnne a emu yɛ den a ɛsɛ sɛ wode kɔ wo duruyɛfo anaa Emergency Department (ETU) nkyɛn ntɛm ara . | |
| Nneɛma a ɛma obi ho yɛ no hyew | Honam ani akisikuru, ɛyaw a emu yɛ den, anim, ano anaa tɛkrɛma a ɛho ahonhon. |
| Ɔhome mu haw ne komayare ho sɛnkyerɛnne | Ɔhome a ɛyɛ den, koko mu yaw, koma a ɛbɔ ntɛmntɛm anaasɛ ɛnyɛ daa. |
| Mogya a ɛtwetwe no ho sɛnkyerɛnne | Ɛyaw, ɔfe, ne kɔkɔɔ wɔ nan no mu (mpɛn pii no nan biako). |
| Nsɛnkyerɛnne afoforo a anibere wom | Akisikuru, ɔfe, atiridiinini, atiridiinini, menewa mu yaw, mogya a ɛtɔ anaa akuru a ɛyɛ soronko, ɔbrɛ a ɛtra so, ɛyɛ den sɛ ɔbɛnantew anaa ɔbɛkasa, anan a ɛho ahonhon. |
| Nsɛnkyerɛnne a ɛtaa ba a ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo sɛ ɛkɔ so anaasɛ ɛhaw adwene a | |
| Nnuan a wɔyam no mu haw ahorow | Atiridiinini, akisikuru, akisikuru, ɔfe, yafunu a ɛnyɛ dɛ. |
| Su afoforo a ɛwɔ hɔ nyinaa | Nsakrae a ɛba wɔ dɛ mu, ano a ɛyɛ mmerɛw, tiyɛ, aduan ho akɔnnɔ a ɛyera, ntini mu yaw. |
Ɔkwan bɛn so na wobetumi ama nnuru ayɛ nea asiane biara nni ho?
- Fa nnuru to baabi a mmofra nkumaa ntumi nkɔ hɔ na wontumi nhu .
- Fa sie wɔ dan mu hyew (a ɛwɔ digrii Celsius 15 kosi 30 ntam). Mfa nneɛma nsie wɔ mmeae a ɛhɔ yɛ nwini kɛse te sɛ aguaree.
- Tow nnuru a ne bere atwam a womfa nni dwuma.
Nkrasɛm a Wɔde Kɔ Fie
- Vorinostat yɛ aduru a wɔde sa kokoram bi a wɔfrɛ no CTCL. Fa eyi sɛnea wo duruyɛfo kyerɛ no bere nyinaa.
- Ka nnuru afoforo a wonom nyinaa ne ayaresa tebea horow a wowɔ nyinaa kyerɛ wo duruyɛfo.
- Mene aduru no nyinaa ne aduan. Mma nwe, nbubu, anaa mmue capsule no.
- Ɛsɛ sɛ wohwɛ yiye bere a wode aduru yi redi dwuma bere a wonyinsɛn, worema nufu, ne sɛ worehwɛ akokoaa kwan a. Di wo duruyɛfo akwankyerɛ akyi.
- Sɛ wunya ɔhaw ahorow a emu yɛ den te sɛ ahome a ɛyɛ den, wo koko mu yaw, anaa mogya a ɛtɔ soronko a, hwehwɛ ayaresa ntɛm ara.
- Sɛ wowɔ nsɛm bi a ɛhaw wo anaa nsɛmmisa bi a, nsuro sɛ wo ne wo duruyɛfo bɛkasa. Ɛyɛ wo hokwan sɛ wubisa nsɛm fa w’akwahosan ho.
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