So w’ani reyɛ kɔkɔɔ? Ebetumi ayɛ Gilbert Syndrome!

So woate nka pɛn sɛ w’ani ne wo honam ani fitaa no reyɛ kɔkɔɔ kakra? Ɛyɛ hu kakra sɛ wubehu saa, ɛnte saa? Ebia wubesusuw sɛ ɛyɛ mmerɛbo mu yare bi. Ade biako a ebetumi de eyi aba ne tebea bi a wɔfrɛ no Gilbert syndrome. Nanso mma nsuro bere a wote din no, ɛnyɛ nea asiane wom sɛnea ebia wubesusuw no. Nokwarem no, ɛyɛ awosu mu tebea kɛse sen yare.

Sɛ yɛbɛka no tiawa a, dɛn ne Gilbert yare no?

Gilbert yare no yɛ tebea a abu so yiye a ɛkɔ so wɔ yɛn mmusua mu, kyerɛ sɛ, efi awosu mu. Obi a ɔwɔ eyi wɔ nwura bi a wɔfrɛ no bilirubin pii wɔ ne mogya mu.

Seesei ebia woresusuw nea bilirubin yɛ ho. Ɛyɛ mmerɛw yiye. Mogya mu nkwammoaa kɔkɔɔ a ɛwɔ yɛn nipadua mu no nso wɔ nkwa nna. Sɛ saa nkwa nna no twam a, wɔsɛe. Bilirubin yɛ kɔla kɔkɔɔ, anaa ade a wɔsɛe no, a ɛba bere a mogya mu nkwammoaa kɔkɔɔ asɛe no. Mpɛn pii no, yɛn mmerɛbo no fa bilirubin yi, ɛyɛ ho adwuma, na ɛnam bile so yi fi nipadua no mu.

Nanso wɔ nnipa a wɔwɔ Gilbert yare no mu no, mmerɛbo no ntumi nyɛ enzyme titiriw bi a ɛyɛ adwuma yi a ɛdɔɔso. Enti wontumi nyi bilirubin mfi hɔ koraa, na emu bi kɔ so tra mogya no mu. Sɛ bilirubin dodow a ɛwɔ mogya no mu kɔ soro a, ɛtɔ mmere bi a aniwa ne honam ani yɛ kɔkɔɔ. Yɛsan frɛ eyi sɛ jaundice .

Dɛn na ɛde tebea yi ba?

Eyi fi nsonsonoe ketewaa bi a ɛwɔ yɛn awosu mu nkwaadɔm mu. Sɛnea yenya nneɛma te sɛ honam ani kɔla ne ti nhwi nwene fi yɛn awofo hɔ no, saa ara na eyi nso yɛ nokware.

Awosu mu abɔde bi wɔ yɛn nipadua mu a wɔfrɛ no UGT1A1 . Saa awosu mu abɔde yi kyerɛ yɛn sɛ yɛnyɛ mmerɛbo mu enzyme a madi kan aka ho asɛm a ɛtew bilirubin ho no. Gilbert yare no fi nsakrae ketewaa bi a ɛba saa awosu mu abɔde yi mu.

Sɛ wubenya saa tebea yi a, ɛsɛ sɛ wunya awosu mu abɔde a wɔayɛ no foforo no mfonini abien. Eyi kyerɛ sɛ ɛsɛ sɛ wunya awosu mu abɔde no fi wo maame ne wo papa nyinaa hɔ . Nanso, sɛ wowɔ awosu abien no nyinaa mpo a, ɛnyɛ obiara na ɔbɛda Gilbert yare no ho sɛnkyerɛnne adi. Afei nso, tebea no abu so wɔ mmarima mu sen mmea.

Dɛn ne Gilbert yare no ho sɛnkyerɛnne?

Nokwarem no, nnipa dodow no ara a wɔwɔ Gilbert yare no nni sɛnkyerɛnne biara koraa . Wɔwɔ mmerɛbo mu enzymes a ɛdɔɔso a ɛbɛma wɔatumi ahwɛ bilirubin dodow a ɛwɔ wɔn nipadua mu no so.

Nea ɛkyerɛ titiriw na ɛtɔ mmere bi a ɛno nkutoo ne aniwa ne honam ani fitaa a ɛyɛ kɔkɔɔ, a wɔfrɛ no jaundice. Sɛ w’ani yɛ kɔkɔɔ a, ɛho hia sɛ wokɔ oduruyɛfo nkyɛn kɔhwɛ wo , efisɛ ebia nneɛma afoforo na ɛde ba.

Nnipa binom betumi anya sɛnkyerɛnne ahorow a edidi so yi aka aniwa a ɛyɛ kɔkɔɔ ho:

• Ɔfe ne yafunu a ɛyɛ yaw
• Yafunu mu a ɛyɛ mmerɛw
• Ɔbrɛ kɛse a wɔte nka (ɔbrɛ) .
• Nsu a ɛyɛ sum

Dɛn nti na ɛtɔ mmere bi nkutoo na m’ani dan kɔla, ɛnyɛ bere nyinaa?

Eyi yɛ asɛmmisa pa. Nneɛma bi wɔ hɔ a ebetumi ama yɛn bilirubin dodow akɔ soro. Eyi ne bere a yɛtaa hu sɛ aniwa no ayɛ kɔkɔɔ.

Ɔkwan bɛn so na wobehu tebea yi?

Ɛwom sɛ Gilbert yare no yɛ tebea a wɔde awo obi de, nanso wɔtaa hu no wɔ nnipa a wɔadi mfe 20 anaa 30 mu. Ɛno nso ba ara kwa.

Fa no sɛ biribi foforo nti na wɔreyɛ wo mogya mu nhwehwɛmu. Afei wo duruyɛfo hu sɛ bilirubin dodow a ɛwɔ wo mogya mu no dɔɔso kakra sen sɛnea ɛte daa. Afei ebia obesusuw sɛ wowɔ Gilbert yare no.

Afei, sɛnea ɛbɛyɛ na oduruyɛfo no ahwɛ ahu sɛ mmerɛbo mu nyarewa afoforo a ɛyɛ hu biara nni hɔ no, obetumi ayɛ nhwehwɛmu ahorow pii, te sɛ:

• Liver Function Tests (LFT): Eyi yɛ mogya mu nhwehwɛmu a wɔtaa yɛ.
• Liver Ultrasound: Sɛnea ɛbɛyɛ a wobɛhwɛ sɛ mmerɛbo mu haw afoforo wɔ hɔ anaa.
• Gene Tests: Si so dua sɛ wowɔ UGT1A1 gene mutation no anaa.
• Liver Biopsy: Wɔntaa nyɛ eyi.

Ayaresa ne nea yɛn ankasa betumi ayɛ

Asɛmpa no ne sɛ nnipa dodow no ara a wɔwɔ Gilbert yare no nhia ayaresa biara , na w’ani a ɛyɛ kɔkɔɔ no remfa ɔhaw biara mma wo bere tenten.

Enti nea ɛsɛ sɛ yɛyɛ ne sɛ yɛbɛtwe yɛn ho afi nneɛma a madi kan aka ho asɛm a ɛma bilirubin dodow kɔ soro no ho sɛnea yebetumi.

• Mma nntwa adidi so, titiriw bere a woredi mmuada no.
• Nom nsu ne nsu pii. Mma wo nipadua mu nsu nnsɛe.
• Di adwennwen ho dwuma. Yɛ biribi a ɛbɛma w’ahome te sɛ adwennwen, nnwom a wobɛtie, anaa anigyede bi a w’ani gye ho a wode wo ho bɛhyɛ mu.
• Da yiye. Anyɛ yiye koraa no, da nnɔnhwerew 7-8 da biara.
• To nsa nom ano hye anaasɛ gyae koraa.
• Kwati apɔw-mu-teɛteɛ a emu yɛ den. Apɔw-mu-teɛteɛ a ɛfata ye, nanso npia wo ho ntra nea wubetumi ayɛ.

Nea ɛsɛ sɛ wuhu bere a worenom nnuru no!

Eyi ho hia paa. Sɛ wowɔ Gilbert yare no a, ɛsɛ sɛ wuhu eyi ansa na woanom nnuru foforo biara.

Enzyme koro no ara a ɛtew bilirubin a ɛwɔ yɛn mmerɛbo mu no nso boa ma ɛpaapae na eyi nnuru bi fi nipadua no mu. Enti, esiane sɛ wowɔ Gilbert yare nti, saa enzyme no dwumadi so tew kakra. Enti, sɛ wonom nnuru a ɛte saa a, ɛboaboa ano wɔ nipadua no mu boro so.Asiane a ɛwɔ hɔ sɛ ebefi mu aba no yɛ kɛse.

Sɛ nhwɛso no, hwɛ nnuru yi:

• Acetaminophen - (Ɛwɔ Panadol, Paracetamol) .
• Irinotecan - aduru a wode sa kokoram
• Nnuru bi a wɔde sa HIV ne hepatitis C (Protease inhibitors) .