Has your doctor told you to start a new injection for diabetes? You may have heard the name a little strange – 'Tirzepatide'. Don't worry. This is a very effective, new drug that is now used to control type 2 diabetes . Let's talk about this drug, how it works, and the things to be careful about while using it, simply, as if you were talking to a friend.
Simply put, what is Tirzepatide?
Tirzepatide is a medication given to people with type 2 diabetes. Your doctor may have given you this under the brand name ``MOUNJARO''. This medication does several very important things in our bodies.
- Increases insulin levels : The hormone insulin is essential for controlling blood sugar levels in our body. This medicine helps control blood sugar ( glucose ) by increasing that insulin level.
- Reduces the release of excess sugar: It also reduces the amount of unnecessary sugar that our body releases into the blood.
- Slows down digestion: This slows down the rate at which sugar from the food you eat enters your bloodstream, which helps control sudden spikes in blood sugar levels .
But remember, this medicine alone is not enough. A good diet and exercise must be combined with this medicine.
Things you need to tell your doctor before taking medicine
Before you start taking this medication, it is very important to give your doctor a complete picture of your health. Be sure to tell your doctor if you have any of the conditions listed below.
| Medical conditions you have/have had | Why should you inform? |
|---|---|
| Pancreatitis | Because this medicine may be contributing to this condition. |
| Kidney disease or gallbladder disease | In such situations, special care should be taken regarding the dosage or use of medication. |
| Eye diseases caused by diabetes | Because rapid changes in blood sugar levels can affect the eyes. |
| Digestive system problems | Because this medicine slows down digestion, it may affect an existing problem. |
| Having a family history of thyroid cancer or a condition called MEN 2 | Because there is a small risk that this medicine may be associated with some types of thyroid cancer. |
| If you are pregnant or trying to get pregnant | You should seek special advice from your doctor about using this medicine during pregnancy. |
| If a mother is breastfeeding her child | You should discuss the effects of the medication with your doctor during breastfeeding. |
| Allergies to other medicines, foods or substances | It is very important to let us know if you are allergic to Tirzepatide or any other ingredients. |
How exactly do you use this medicine?
This medicine comes as an injection under the skin. Your doctor or nurse will show you exactly how to give it. Don't worry, it's very simple.
- Once a week: This vaccine should only be given once a week (exactly once every 7 days).
- Follow medical advice: Continue using this until your doctor tells you to stop.
- If you use insulin: If you also use insulin injections, never mix the two injections. Inject the two injections separately, a little distance apart.
- Change the injection site: Each time you get an injection, don't inject the same spot as before, but inject it in a slightly different spot (for example, if you get one on one side of your stomach, the next time you get the other side). This is called ``rotating injection sites''.
- Read the package insert: Read the package insert that comes with the medicine carefully. If you have any questions, ask your doctor.
Very important: Never throw your used needles and syringes in the trash. They should be placed in a special sharps container that can be removed. If you don't have one, ask your doctor about how to get one.
What if the medication dose increases?
If you suspect that you have taken an overdose, do not panic. Go to the nearest hospital Emergency Department (ETU) immediately. Or call the National Poisons Information Centre at the Colombo National Hospital .
What to do if you miss a dose of medication?
Sometimes you may forget to get vaccinated. If so:
- If it has been less than 4 days (96 hours) since you missed your dose, get the vaccine as soon as you remember.
- However, if more than 4 days have passed since you forgot, skip that dose completely. Just get your next dose on the next scheduled day, at the scheduled time, as usual.
- Never get two vaccines within 3 days.
Other things that may interact with this medicine
Other medications, vitamins, and herbal remedies you take may interact with this medicine. So it's important to tell your doctor about everything you're taking. Be especially careful about the following:
- Other medications for diabetes (e.g. glyburide, glipizide)
- Aspirin and similar painkillers
- Some medications for blood pressure or heart disease (e.g. `Beta blockers` – metoprolol, propranolol)
- Pain and inflammation medications (NSAIDs) – e.g. ibuprofen, naproxen
- Steroid-type medications (e.g. prednisone, cortisone)
- Some antibiotics (Quinolone antibiotics)
- Take medicine to lose weight
- Alcohol
- Some herbal products
This list is not exhaustive. So be sure to tell your doctor about all medications, vitamins, and herbal remedies you take. Also tell your doctor if you smoke or drink alcohol.
Things to be careful about when taking medication
There are several things you should pay attention to when using this medicine.
- Regular medical check-ups: Go to the clinics at the scheduled times as prescribed by the doctor and get yourself checked. The doctor will monitor your `HbA1C` (a test that shows your average blood sugar levels over the past 2-3 months) level.
- Low blood sugar (Hypoglycemia): This is very important. Be aware of the symptoms of low blood sugar ( dizziness , sweating, restlessness, extreme hunger). Always carry a small amount of sugar, such as a candy bar or glucose tablet. If your blood sugar drops too low and you become unconscious, tell your family not to put anything in your mouth. If this happens, seek medical attention immediately.
- Do not share your pen: Never share your pen with anyone else, even if you change the needle. Doing so can spread infections.
- Thyroid cancer risk: There is talk of a very small risk of thyroid cancer in people taking this medication. So if you have a lump or swelling in your neck, a change in your voice, difficulty swallowing, or difficulty breathing, tell your doctor right away.
- Stay hydrated: Drink plenty of water while taking this medication. If you experience vomiting or diarrhea, you may lose a lot of water from your body. If this happens, inform your doctor.
- Birth control: If you are taking oral contraceptive pills, this medicine may make them less effective. Therefore, talk to your doctor about using another form of birth control (such as condoms) for the first 4 weeks after starting this medicine and for 4 weeks after each dose increase.
What are the possible side effects?
Like any medicine, this one can cause side effects in some people. Some of them require immediate attention, while others are normal.
| Type of side effect | Characteristics |
|---|---|
| Serious side effects that should be reported to the doctor immediately | |
| Allergic reactions | Skin rash, itching, swelling of the face, lips, tongue or throat. |
| Pancreatitis | Severe stomach pain (especially in the back), pain that gets worse after eating, vomiting, fever. |
| Thyroid cancer symptoms | A lump in the neck, difficulty swallowing, voice changes. |
| Kidney damage | Decreased urine output, swelling of the legs and ankles. |
| Gallbladder problems | Severe pain in the upper right abdomen, nausea, vomiting, fever. |
| Side effects that are usually common, but should be reported to the doctor if they persist | |
| Digestive system problems | Nausea, vomiting, stomach pain, diarrhea, constipation. |
| Appetite | Decreased appetite. |
How to store the medicine?
It is also very important to store this medicine properly.
- The best way to store it is in the refrigerator: The refrigerator is the best. But do not store it in the freezer. Keep the medicine in the original box.
- Storage at room temperature: If necessary, it can be stored at room temperature below 30 degrees Celsius for up to 21 days. However, if so, it should be used within 21 days.
- Protect from light and excessive heat.
- Do not use expired medicine.
Consult your doctor about how to safely dispose of unused or expired medications.
Take-Home Message
- Tirzepatide is a once-weekly injection for type 2 diabetes.
- Before starting this medication, tell your doctor about all your medical conditions and all other medications you are taking.
- Be aware of the symptoms of low blood sugar (hypoglycemia). Always keep some sugar or a piece of candy nearby.
- Never share your injection pen with anyone else.
- If you experience any unusual symptoms, such as a lump in your neck or severe stomach pain, seek medical advice immediately.
- If you have any questions about this medicine, don't be afraid to talk to your doctor.
Tirzepatide, Mounjaro, diabetes, blood sugar, insulin, diabetes vaccine
👩🏽⚕️ Additional questions (FAQs)
💬 What kind of medicine is Tirzepatide / Mounjaro?
Tersepatide is a new, innovative drug that is injected under the skin once a week to treat type 2 diabetes. It increases the body's production of insulin, significantly reducing the rise in blood sugar after eating.
💬 Is it true that this medicine helps you lose weight?
Yes, the biggest advantage of this medicine is that it sends the feeling of fullness to the brain, which greatly reduces our appetite. Therefore, many people lose extra weight and fat quickly when they take this.
💬 What are the side effects of using this medicine?
Many people feel full at first, which can lead to side effects such as vomiting, nausea, stomach cramps, and diarrhea. To minimize these, doctors start with a small dose and gradually increase the dose.











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