Skip to main content
🎂 — | ♂/♀ M/F | ⚖️ — kg | 📏 — cm | BMI — | 👟 —
⚡ 88%
🩺 General Health Information

Are you always tired? Feeling sluggish? Let's learn about the factors that increase the risk of Chronic Fatigue Syndrome (ME/CFS).

MBBS
Medically Reviewed by MBBS ✓ Medically Reviewed
📅 Updated: Jul 14, 2026 • ⏱ 5 min read • Editorial policy
Are you always tired? Feeling sluggish? Let's learn about the factors that increase the risk of Chronic Fatigue Syndrome (ME/CFS).
Table of Contents ▾

Some days we feel really tired, don't we? But when we get a good night's sleep and some rest, that tiredness goes away. But imagine, for no reason, no matter how much rest you take, you feel so tired that it takes your life away? Today we are going to talk about such a condition as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, or ME/CFS for short. Doctors still don't know exactly what causes it. But they believe that some people are at a slightly higher risk of developing it. Let's take a look at what those risk factors are.

⚡ Interactive Clinical Tool
⚖️

BMI Calculator

Know your body mass index (BMI) and weight classification

Open Interactive Calculator →

How do age and gender affect?

Surprisingly, ME/CFS is more common in women than in men. In fact, women are about four times more likely to develop it than men. So if you're a woman, it's a good idea to pay a little more attention to this.

This disease is very rare among young children, but even at that age, girls are more likely to develop it than boys.

If we look at adults, this disease usually begins in people between the ages of 30 and 50. Among young children, this condition is most common in those between the ages of 13 and 15.

This information does not mean that men or other age groups do not develop this disease. It only indicates the groups that are statistically at higher risk.

Yes, it can be genetic. If someone in your family, such as your mother, father, or sibling, has ME/CFS, you may be at a slight risk of developing it too. Simply put, this risk can be caused by a weakness in the genes we inherit from our parents.

But it's not just the structure of the genes that matters here. What's even more important is whether those genes are 'turned on' correctly . It's like turning a light switch on and off. Research has found that people with ME/CFS have changes in how these genes work, especially in parts of the body like white blood cells .

For example, it has been found that genes that stimulate our immune system and prepare it to fight may be constantly 'on' or overactive in the bodies of these patients. This is why they often feel tired and lifeless.

The relationship between genes and environment

Many diseases are caused not only by genes, but also by factors in the environment we live in. That is:

  • Bacterial infections
  • Toxins
  • Our diet
  • Severe stress
  • Exercise pattern

ME/CFS may be caused by both genetic and environmental factors . This means that even if someone is genetically predisposed, they can still be triggered by something like an infection or severe stress.

Other diseases that can occur with this disease

People with ME/CFS are more likely to have other conditions. It's possible that one condition increases the risk of developing ME/CFS. Or it could be that ME/CFS causes other conditions. Doctors still don't fully understand this connection. Let's take a look at some of the most common conditions.

Condition A simple explanation
Fibromyalgia A condition that causes pain throughout the body, severe fatigue, and sleep problems.
Irritable Bowel Syndrome (IBS) A digestive system disease that causes stomach pain, bloating, and changes in bowel habits (constipation or diarrhea).
Multiple chemical sensitivities Hypersensitivity of the body to odors and chemicals in the general environment.
Temporomandibular disorders (TMD or TMJ) Pain and functional problems in the jaw joint and chewing muscles.
Interstitial cystitis A condition that causes pain in the bladder or pelvis.
Post-concussion syndrome Persistent symptoms (such as headaches, dizziness) after a head injury.
Tension headache Common headaches caused by stress.
Chronic pelvic pain (in women) Long-term pain in the pelvic area in women.
Chronic prostatitis (in men) Long-term inflammation and pain in the prostate gland in men.

If you have one or more of these symptoms, or if you are concerned or suspect that you may have ME/CFS, please talk to your family doctor about it. Do not self-diagnose by searching for information on the internet. Your doctor is the best place to get the best advice and guidance.

💡 Take-Home Message

  • Chronic Fatigue Syndrome (ME/CFS) is a real, debilitating condition. It's not "bored" or "exhausted."
  • Women, especially those between the ages of 30-50, are at higher risk of developing this disease.
  • If someone in your family has had this condition, you may also have a small genetic risk.
  • Having other medical conditions, such as fibromyalgia or IBS, can increase the risk of ME/CFS.
  • Most importantly, if you have any doubts or fears about this, do not make decisions on your own and consult your doctor immediately for advice.
🔍 Search Keywords: what makes chronic fatigue likely • what makes chronic fatigue likely symptoms • what makes chronic fatigue likely causes and treatment • what makes chronic fatigue likely sri lanka • Are you always tired? Feeling sluggish? Let's learn about the factors that increase the risk of Chronic Fatigue Syndrome (ME/CFS).

🩺 Articles For You

Little red creatures crawling along the walls of the house! Let's learn about these Clover Mites!

Are you 'neurotypical'? Let's talk about this simply!

What is an Internist? Let's talk about this simply.

Do you also have a problem with your tooth enamel? Let's talk about (Amelogenesis Imperfecta)!

What is Biohacking? Shall we talk about this new trend?

Want to learn about responsible travel? (Ecotourism) Let's talk about it!

💬 Patient Questions & Comments (0)

Have a question or experience to share? Post a comment or reply to other readers below.

🛡️ Plain Text Only • No Links
👤

No comments yet. Be the first to share your question or experience below.

⚠️ Important: Medical articles and information on Nirogi Lanka are strictly for educational and awareness purposes and do not substitute professional medical advice, diagnosis, or treatment. Always consult a qualified physician for any medical concerns.