Ðe wò lãmekawo hã le gbɔdzɔgbɔdzɔm? Esia ate ŋu anye myotonic dystrophy!

Ðe nèse le ɖokuiwò me kpɔ be wò abɔ kple afɔ siwo sesẽ tsã la le ƒoƒom alo le gbɔdzɔgbɔdzɔm vivivia? Alo ɖe wòsesẽna na wò ɣeaɖewoɣi be nàʋu asi ne èlé nane ɖe asi sesĩea? Esiawo nye nusiwo ŋu míeléa ŋku ɖo boo ɣeaɖewoɣi o, gake woate ŋu anye dɔléle aɖe si woyɔna be Myotonic Dystrophy ƒe dzesiwo. Mina míaƒo nu tso esia ŋu tsitotsito eye míaƒo nu tso eŋu egbea ko.

Nukae nye Myotonic Dystrophy?

Kpuie ko la, Myotonic Dystrophy (DM) nye domenyiŋusẽfianu ƒe dɔléle sesẽ aɖe. Nu vevitɔ si le esia mee nye be lãmeka siwo le míaƒe ŋutilã me la vuvu vivivi eye wogbɔdzɔna. Ðewohĩ amesiwo ŋu dɔléle sia le ƒe lãmekawo maɖe dzi ɖi enumake le wo zazã vɔ megbe o, gake ate ŋu anɔ anyi. Míeyɔa esia be myotonia . Ele abe ʋɔtruti aɖe léle sesĩe eye agbagbadzedze be yeaʋui xɔa ɣeyiɣi aɖe ene.

Myotonic dystrophy (DM) ƒe dzesiwo ate ŋu akeke ta ŋutɔ. Ate ŋu akpɔ ŋusẽ ɖe míaƒe ŋutilã ƒe ɖoɖo vovovowo dzi. Le kpɔɖeŋu me:

• Míaƒe ƒunukpeƒeŋusẽwo (lãmeka siwo dzi míeɖonɛ koŋ ɖuna) kple dzitodzito me lãmekawo.
• Ŋkuwo.
• Dzitodzito me ʋukawo ƒe dɔwɔwɔ (ʋu ƒe sisi ƒe ɖoɖo).
• Endocrine system (lãmetsiŋusẽ ƒe ɖoɖo).
• Titina lãmekawo ƒe dɔwɔwɔ (ahɔhɔ̃ kple aklã).

Ðe myotonic dystrophy ƒomevi aɖewo lia?

Ẽ, DM ƒomevi vevi evee li:

1. Myotonic dystrophy type 1 (DM1): Wogayɔa esia be Steinert dɔléle . DM1 ga ƒe ƒomevi sue ene le esi:

• Klasik ƒomevi
• Ƒomevi fafɛ
• Vidzidzi ƒomevi (si nɔa anyi le edziɣi) .
• Ðevimenɔɣi ƒe ƒomevi

2. Myotonic dystrophy type 2 (DM2): Wogayɔa esia be proximal myotonic myopathy .

Dɔlékui ƒomevi evea siaa ƒe dzesiwo ate ŋu asɔ ɣeaɖewoɣi. Gake zi geɖe la, DM2 fa vie wu DM1, si fia be dzesiawo mesẽna nenema gbegbe o.

Vovototo kae le Lãmetsiŋusẽ ƒe Dɔléle kple Lãmetsiŋusẽ ƒe Dɔléle dome?

Esia nye nusi tɔtɔa ame geɖe. Lãmetsiŋusẽ ƒe dɔmawɔmawɔ nyuie nye dɔléle siwo ƒe dome wonyi (domenyiŋusẽfianu) ƒe ƒuƒoƒo. Dɔléle ƒomevi siwo wu 30 ye le ƒuƒoƒo sia me. Wo katã nana lãmekawo gbɔdzɔna. Esiawo dze le myopathy , si nye míaƒe ƒunukpeƒeŋusẽ ƒe dɔléle ƒe hatsotso me. Le ɣeyiɣi aɖe megbe la, lãmekaawo dzi ɖena kpɔtɔna eye wogbɔdzɔna. Esia wɔnɛ be azɔlizɔzɔ kple gbesiagbedɔwo wɔwɔ sesẽna. Ɣeaɖewoɣi la, ate ŋu agblẽ nu le dzi kple lãkusi hã ŋu.

Myotonic Dystrophy ƒe DɔléleEnye dɔléle ƒomevi aɖe si le lãmekawo ƒe dɔmawɔmawɔ nyuie ƒe ƒuƒoƒo si míeyɔ va yi la me. Nu tɔxɛae nye be le lãmekawo ƒe dɔmawɔmawɔ nyuie siwo dzea egɔme tso ame tsitsi me dome la, myotonic dystrophy ƒe nɔnɔme siae bɔ wu. (Gake DM ƒomevi aɖewo ate ŋu adze egɔme tso vidzĩme alo ɖevimenɔɣi hã).

Amekae ate ŋu axɔ myotonic dystrophy? Ðe vovototo aɖe le ƒe si woxɔ mea?

DM ƒomevi vovovowo ate ŋu adze egɔme tso ƒe vovovowo me. Na míakpɔ alesi:

• Classic myotonic dystrophy type 1 (Classic DM1): Zi geɖe la, esia dzea egɔme le ƒe 20, 30, alo 40-awo me.
• Mild myotonic dystrophy type 1 (Mild DM1): Esia ate ŋu adze amesiwo xɔ tso ƒe 20 va ɖo ƒe 70 dzi, gake ebɔ wu le ƒe 40 xɔxɔ megbe.
• Congenital myotonic dystrophy type 1 (Congenital DM1): Abe alesi nya "congenital" ɖee fia ene la, esia nye ƒomevi aɖe si dzea vidzĩwo dzi. Esia fia be ele afima tso esime wodzii.
• Childhood myotonic dystrophy type 1 (Childhood DM1): Zi geɖe la, esia dzea egɔme le ƒe 10 xɔxɔ lɔƒo.
• Myotonic dystrophy type 2 (DM2): Esia hã dzea egɔme tso ame tsitsi me. Zi geɖe la, dzesiawo dzea egɔme tso ƒe 48 lɔƒo.

Aleke gbegbee dɔléle sia bɔe?

Myotonic dystrophy (DM) dzea ame 1 le 8,000 ɖesiaɖe me ya teti dzi le xexeame godoo. Gake xexlẽme sia ate ŋu ato vovo le anyigba ƒe nuto kple to si me wotso nu. DM ye nye lãmekawo ƒe dɔmawɔmawɔ nyuie ƒomevi si bɔ wu le Europatɔwo dome.

Le ameha akpa gãtɔ me la, DM ƒomevi 1 (DM1) bɔ wu DM ƒomevi 2 (DM2).

Nukae nye Myotonic Dystrophy ƒe dzesiwo?

Esiawoe nye DM ƒe dzesi vevitɔwo. Vivivi la, wogblẽna ɖe edzi le ɣeyiɣi aɖe megbe, si fia be wova nu sẽna ɖe edzi:

• Lãmetsiwo ƒe gbagbã: Lãmetsiwo ƒe gbegblẽ.
• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ: Lãmetsiwo ƒe ŋusẽ dzi ɖe kpɔtɔ.
• Myotonia: Míeƒo nu tso esia ŋu kpɔ. Ŋutete si mele ame si be wòaɖe dzi ɖi le nyanya me na lãmeka aɖe o. Le kpɔɖeŋu me, ne ame aɖe si ŋu DM le nya lé ʋɔtruti aɖe ko la, ate ŋu asesẽ vie be wòaɖe asi le eŋu.

Gake esi wònye be DM gblẽa nu le ŋutilã ƒe akpa vovovowo ŋu ta la, dzesi bubu vovovowo ate ŋu ado mo ɖa. Dzesi siawo ƒe sesẽme kple alesi wodzenae la toa vovo le DM ƒomevi si le wo ŋu nu.

Dzesiwo le Classic Myotonic Dystrophy Ƒomevi 1 ŋu

Dzesi sia ƒomevi dzea egɔme tso ame tsitsi me. Myotonia ye nye dzesi vevitɔ si wokpɔna zi gbãtɔ. Esia dzena wu le ɖiɖiɖeme megbe eye ate ŋu aɖe akpɔtɔ vie le lãmekawo ƒe dɔwɔwɔ megbe.

Dzesi bubuwoe nye:

• Lãmetsi siwo le didiƒe ƒe gbɔdzɔgbɔdzɔ:Esia fia be lãmeka siwo didi tso ŋutilã ƒe titina gbɔ (e.g., lãmeka siwo le abɔwo kple afɔwo me) gbɔdzɔna. Esia wɔnɛ be esesẽna be woawɔ dɔ sesẽwo kple asiwo (e.g., abɔta, nuŋɔŋlɔ). Enaa azɔlizɔzɔ hã sesẽna le nɔnɔme aɖe si woyɔna be afɔdzidede ta (abe ɖe afɔa ƒe gɔme le hehem ɖe anyigba ene).
• Mo ƒe lãmekawo ƒe vuvu nana mo ƒe nɔnɔme va nɔa tsɛ, si le ɖaɖɛ (mo si me lãmekawo ƒe dɔwɔwɔ le) .
• Dzi ƒe ʋuʋu ƒe dɔmawɔmawɔ nyuie.

Dzesi Siwo Le Vidzidzi ƒe Myotonic Dystrophy Ƒomevi 1 Ŋu

Esi wònye be vidzĩ sia ƒomevi nɔa vidzidzi me ta la, ate ŋu aɖe dzesi aɖewo afia esime wògakpɔtɔ le vidzidɔa me:

• Fugboe ƒe ʋuʋu dzi ɖe kpɔtɔ le vidzidɔa me.
• Polyhydramnios nye vidzidɔ me tsi si sɔ gbɔ akpa si ƒo xlã fugboea le fufɔɣi.
• Clubfoot ( afɔ si trɔ ɖe eme).
• Ventriculomegaly (ahɔhɔ̃ ƒe ʋukawo ƒe lolome) (le ahɔhɔ̃mekawo ƒe tsi ƒe ƒoƒo ƒu ta).

Dzesi siwo wokpɔna le ɖeviwo kple ame tsitsiwo ŋu le wo dzidzi megbe:

• Nuyi si le etame la le abe agbadɔ ene le mo ƒe lãmekawo ƒe gbɔdzɔgbɔdzɔ ta.
• Nuƒoƒo si me mekɔ o (Dysarthria) .
• Susu ƒe nuwɔametɔnyenye.
• Le myotonia teƒe la, lãmekawo ƒe dɔwɔwɔ dzi ɖena kpɔtɔna (Hypotonia) .

Dzesiwo le Mild Myotonic Dystrophy Ƒomevi 1 lia ŋu

Zi geɖe la, dzesi sia ƒomevi dzea egɔme tso ƒe 20 va ɖo ƒe 70. Wo dometɔ aɖewoe nye:

• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ fafɛ.
• Lãmetsiŋusẽ ƒe dɔléle (Myotonia).
• Ŋku ƒe ʋuʋu .

Ðevimenɔɣi ƒe Myotonic Dystrophy Ƒomevi 1 ƒe Dzesiwo

Zi geɖe la, dzesi sia ƒomevi dzea egɔme ne woxɔ ƒe 10. Wo dometɔ aɖewoe nye:

• Nusɔsrɔ̃ ƒe kuxiwo kple susu kple hadomekuxiwo (e.g. ƒomekuxiwo, blanuiléle, dzimaɖitsitsi).
• Nuƒoƒo si me mekɔ o.
• Asiwo ƒe lãmekawo ƒe myotonia.
• Dzi ƒe ʋuʋu ƒe dɔmawɔmawɔ nyuie.

Myotonic Dystrophy Ƒomevi 2 ƒe dzesiwo

Zi geɖe la, DM ƒomevi evelia ƒe dzesiwo dzea egɔme tso ame tsitsi me eye woate ŋu ato vovo.

Dzesiawo ate ŋu anye:

• Gbɔdzɔgbɔdzɔ alo lãmeka siwo te ɖe ŋutilã ƒe titina ŋu ƒe tete (e.g., lãmeka siwo ƒo xlã akɔta kple abɔta).
• Myofascial pain (vevesese le lãmekawo kple kadodoŋusẽwo me) .
• Ŋkuʋuʋu ƒe gɔmedzedze kaba (hafi wòaxɔ ƒe 50).
• Myotonia si ƒe agbɔsɔsɔme le vovovo la dzɔna ne wotsɔ asi lé nane.
• Tosese ƒe kuxi.

Vevesese nye nyatoƒoetoto gã aɖe le amesiwo ŋu DM2 le dome. Ame siawo gblɔna be yewosea veve le ƒodo, ƒunukpeƒewo, kple le kamedede me.

Nukae hea Myotonic Dystrophy vɛ?

Myotonic dystrophy (DM) nye domenyiŋusẽfianu ƒe dɔléle , si fia be etsoa dzilawo gbɔ yia ɖeviwo gbɔ to domenyiŋusẽfianuwo dzi.

DM ƒomevi 1 (DM1) tsoa domenyiŋusẽfianu si woyɔna be DMPK ƒe tɔtrɔ (trɔtrɔ) gbɔ. DM ƒomevi 2 (DM2) tsoa domenyiŋusẽfianu si woyɔna be CNBP ƒe tɔtrɔ gbɔ.

Tɔtrɔ mawo tɔgbe le domenyiŋusẽfianu eveawo siaa ƒe wɔwɔme me, DMPK kple CNBP, ye hea DM1 kple DM2 vɛ. Le go ɖesiaɖe me la, wogbugbɔa DNA ƒe akpa aɖe wɔa zi geɖe le mɔ si mesɔ o nu. Esia nana nuto aɖe si meli ke o nɔa domenyiŋusẽfianu la me. Zi alesi wogbugbɔa DNA ƒe akpa sia wɔna le mɔ si mesɔ o nu la, zi nenemae DM ƒe dzesiwo nu sẽna ɖe edzii.

Dzɔdzɔmeŋutinunya me kpeɖodziwo ɖee fia be dɔla RNA si sɔ gbɔ si DNA ƒe gbugbɔgagblɔ siawo siwo mesɔ o wɔna la nye aɖi. Esia gblẽa protein vovovowo ƒe wɔwɔ me le lãmenugbagbeviwo me, eye esiae hea myotonic dystrophy ƒe dzesiwo vɛ le ŋutinu vovovowo me.

Alesi dɔléle sia tso dzidzime yi dzidzime (Myotonic Dystrophy Inheritance) .

Wonyia DM ƒomevi eveawo siaa ƒe dome le ɖoɖo aɖe si woyɔna be autosomal dominant nu . Le ɖoɖo sia nu la, dzila ɖeka koe wòle be domenyiŋusẽfianu si ŋu dɔlélea le nanɔ esi hafi dɔlélea nate ŋu ana ɖevi. Dzila si si autosomal dominant trait le ƒe viwo ƒe afã anyi nɔnɔmea dome.

Esi myotonic dystrophy type 1 (DM1) le dzidzim ɖe edzi tso dzidzime ɖeka me yi bubu me la, zi geɖe la, ƒe si woxɔ hafi dzea egɔme la nɔa sue wu eye dzesiawo nu sẽna ɖe edzi. Woyɔa nudzɔdzɔ sia be mɔkpɔkpɔ . Ðeko wòle abe ɖe dɔlélea "le du dzi" tso dzidzime ɖeka yi bubu me ene.

Aleke wokpɔa dɔléle si nye Myotonic Dystrophy? (Dɔléle ƒe dzesi) .

Ne DM ƒe dzesiwo le ŋuwò la, ɖɔkta aɖe ado wò kpɔ gbã eye wòabia nya wò tso:

• Wò ŋutɔ wò atikewɔwɔ ŋutinya.
• Ƒomea ƒe atikewɔwɔ ŋutinya, vevietɔ ne DM le ƒomea me tɔ aɖe ŋu.
• Wò dzesiwo.

Le ema megbe la, woate ŋu awɔ atikewɔwɔ me dodokpɔ aɖewo atsɔ aɖo kpe edzi be wokpɔ DM.

Dodokpɔ ka ƒomevie wowɔna?

Domenyiŋusẽfianu dodokpɔ ate ŋu aɖo kpe DM ƒe dzesi dzi. Dodokpɔ siawo dia tɔtrɔ siwo le DMPK domenyiŋusẽfianu (na DM1) alo CNBP domenyiŋusẽfianu (na DM2) me.

Ne wò ɖɔkta susui be DM alo dɔléle bubu aɖe le ŋuwò la, ate ŋu awɔ dodokpɔ siawo dometɔ ɖeka alo esi wu nenema hafi aɖo wò ɖe domenyiŋusẽfianu dodokpɔ:

• Creatine kinase ʋudodokpɔ: Creatine kinase nye enzyme si le dzitodzito kple ƒumeŋuɖui ƒe lãmekawo me koŋ. Ne lãmeka siawo gblẽ la, enzyme sia ƒoa ƒu ɖe ʋua me. Amesiwo ŋu DM fafɛ le ate ŋu adzi ɖe edzi vie ko ƒe agbɔsɔsɔ sia, alo ate ŋu anye nusi sɔ.
• Elektrikŋusẽŋununya (EMG): .Le dodokpɔ sia me la, wotsɔa elektrikŋusẽnamɔ̃ tsɛ aɖe si le abe aŋe ene dea lãmekaa me eye wodzidzea elektrikŋusẽ si le lãmekaawo me. Zi geɖe la, elektrikŋusẽ geɖe nɔa amesiwo ŋu DM le ƒe lãmekawo me eye womewɔa dɔ boo o, ne wole ɖiɖim ɖe eme gɔ̃ hã.
• Lãmetsiwo ɖeɖe: Le esia me la, ɖɔkta aɖe ɖea lãkusi sue aɖe tso wò lãmeka me hedoa ekpɔ le nusuekpɔmɔ̃ me be yeakpɔe ɖa be DM ƒe dzesiwo li hã.

Ðe woagawɔ dodokpɔ bubuwo ne woɖo kpe dɔlélea dzia?

Ẽ, ne dodokpɔ siawo ɖo kpe DM dzi la, wò ɖɔkta ate ŋu aɖo aɖaŋu be nàgawɔ dodokpɔ bubuwo atsɔ akpɔ ŋutinu aɖewo siwo dzi DM ate ŋu akpɔ ŋusẽ ɖo ƒe dɔwɔwɔ. Le kpɔɖeŋu me:

• Electrocardiogram (ECG) dodokpɔ aɖe si wowɔna tsɔ léa ŋku ɖe dzia ƒe dɔwɔwɔ ŋu.
• Aklã ƒe dɔwɔwɔ dodokpɔ be woatsɔ akpɔe ɖa be ahɔhɔ̃mekawo ƒe gbɔgbɔtsixe ƒe kuxiwo le wo ŋu hã.
• Alɔ̃dɔdɔ ŋuti numekuku aɖe si wowɔ be woatsɔ akpɔe ɖa be alɔ̃dɔdɔ ƒe gbɔgbɔtsixe tsia ame ƒo kple alɔ̃dɔdɔ fũu akpa le ŋkeke me hã .

Ðe atike aɖe li na Myotonic Dystrophy?

Nublanuitɔe la, womekpɔ atike aɖeke na myotonic dystrophy (DM) haɖe o. Eyata atikewɔwɔ ƒe taɖodzinu vevitɔwoe nye:

• Dzesiwo dzi kpɔkpɔ.
• Agbenɔnɔ ƒe nyonyome kple ɖokuisinɔnɔ ƒe ɖoƒe kɔkɔtɔ kekeake me léle ɖe asi.

Esi wònye be DM gblẽa nu le ŋutilã ƒe akpa vovovowo ŋu ta la, atikewɔwɔ ate ŋu ato vovo le wò dzesiwo nu. Esiawo ate ŋu anye:

• Atike siwo woatsɔ aɖe myotonia si nɔa anyi ɖaa dzi akpɔtɔ. Le kpɔɖeŋu me, nusiwo xea mɔ na sodium ƒe mɔxenuwo abe Mexiletine , Tricyclic blanuilélenutsitikewo , Benzodiazepines , alo Calcium mɔxenuwo ene .
• CPAP mɔ̃ aɖe si wotsɔ xea mɔ na alɔ̃dɔdɔ ƒe gbɔgbɔtsixetsixe.
• Atike siwo doa ŋusẽ ame abe methylphenidate ene na alɔ̃dɔdɔ fũu akpa le ŋkeke me.
• Ŋku ƒe dɔwɔwɔ nye amekoko si wowɔna tsɔ ɖea ŋkumeɖonu si xea mɔ na nukpɔkpɔ.
• Suklidɔ ƒe atikewɔwɔ. Esia ate ŋu abia be woazã atikekuiwo kple/alo insulin . Ame siwo ŋu DM le la ate ŋu axɔ suklidɔ le insulin ƒe dɔmawɔmawɔ nyuie ta .
• Testosterone zazã na ŋutsuwo ƒe ʋumenugbagbeviɣidɔ . Zi geɖe la , ŋutsu siwo ŋu DM1 le la ƒe testosterone ƒe agbɔsɔsɔ dzi ɖena kpɔtɔna eye woƒe tsitretsitsi ƒe dɔmawɔmawɔ nyuie .

Lãmesẽfefewɔwɔ kple dɔwɔwɔ ƒe atikewɔwɔ nye atikewɔwɔ vevi siwo ana amesiwo ŋu DM le nanɔ wo ɖokui si wu. Woate ŋu akpe ɖe ŋuwò nàdo ŋusẽ wò lãmekawo eye nàsrɔ̃ mɔ yeye siwo dzi nàto awɔ gbesiagbedɔwo. Àte ŋu alé ɖokuisinɔnɔ me ɖe asi hã to kpekpeɖeŋunu siwo wozãna (e.g., akɔtaɖonuwo, atikplɔwo, bunɔkekewo) zazã me.

Nuƒoƒo kple gbegbɔgblɔ ƒe dɔléle (SLP) ate ŋu akpe ɖe ame ŋu le nu mimi ƒe kuxiwo (Dysphagia) kple nuƒoƒo si me mekɔ o (Dysarthria) me .

Ðe woate ŋu axe mɔ ɖe myotonic dystrophy ƒe dzɔdzɔ nua?

Esi wònye be DM nye domenyiŋusẽfianu ƒe dɔléle ta la, naneke meli nàte ŋu awɔ atsɔ axe mɔ ɖe enu o.

Hafi nàdzi vi la, ne ètsi dzi ɖe afɔku si le DM alo domenyiŋusẽfianu ƒe dɔléle bubuwo tsɔtsɔ na viwòwo ŋu la, ƒo nu kple wò ɖɔkta tso domenyiŋusẽfianu ŋuti aɖaŋuɖoɖo ŋu .

Nukae nye dɔléle sia ƒe ŋgɔdonya?

Mɔkpɔkpɔ na myotonic dystrophy (DM) nɔ te ɖe dɔlélea ƒomevi kple ƒe si me dzesiawo dzea egɔme tsoe dzi. Zi geɖe la, ne dzesiawo dze egɔme tso eƒe tsitsime la, emetsonua mate ŋu anyo o eye ate ŋu aɖe agbenɔƒe dzi akpɔtɔ.

Ame siwo ŋu DM1 le la dometɔ siwo ade 50% ahiã bunɔkeke hafi woate ŋu aku. Zi geɖe la, mehiãa kpekpeɖeŋunu siwo ŋu DM2 le hafi woate ŋu azɔ o elabena woƒe dzesiwo mesẽna o.

Nukae nye ame si ŋu Myotonic Dystrophy le ƒe agbenɔƒe?

Ame si ŋu DM le ƒe agbenɔƒe le mama dedie nu toa vovo le dɔléle ƒomevi si le eŋu nu.

• Le vidzĩ siwo ŋu wodzi DM1 le dome la, vidzĩ siwo kuna ƒe agbɔsɔsɔme anɔ abe 18% ene. Amesiwo ŋu wodzi DM1 le la dometɔ siwo ade 25% kuna hafi woxɔa ɣleti 18, eye abe 50% ene kuna hafi woxɔa ƒe 30.
• Zi geɖe la, amesiwo ŋu DM1 fafɛ le la nɔa agbe si sɔ.
• Ame siwo ŋu Classic DM1 le ƒe agbenɔƒe nɔa kpuie wu amehawo katã.

Ðe Myotonic Dystrophy ate ŋu awu amea?

Ẽ, myotonic dystrophy (DM) ate ŋu awu ame. Gake ƒe si ame kuna la toa vovo le dɔléle ƒomevi si le ame ŋu nu. Nusi koŋ gbɔ wòtsona be DM kunae nye gbɔgbɔtsixe ƒe dɔmawɔmawɔ nyuie si do ƒome kple ahɔhɔ̃mekawo . Dzitodzito me kuxiwo hã ate ŋu anye nusi gbɔ ku tsona.

Ɣekaɣie wòle be nàkpɔ ɖɔkta le myotonic dystrophy ŋu?

Ne DM ƒe dzesiwo abe lãmekawo ƒe gbɔdzɔgbɔdzɔ kple myotonia ene le ŋuwò la, kpɔ egbɔ be yeyi ɖɔkta gbɔ.

Ne DM le ŋuwò la, ele be nàdo go kple wò atikewɔlawo ƒe ƒuƒoƒoa edziedzi akpɔ egbɔ be yeƒe atikewɔwɔ ƒe ɖoɖo si li fifia le dɔ wɔm nyuie.

Ne wokpɔ dɔléle yeye aɖe na wò alo viwòa la, ate ŋu asesẽ be nànɔ te ɖe enu. Gake ɖo ŋku edzi be menye amesiame si ŋu myotonic dystrophy (DM) le lae wògblẽa nu le nenema ke o. Nu nyuitɔ si nàte ŋu awɔe nye be nàƒo nu kple eŋutinunyala bibi aɖe si wɔa numekuku le DM ŋu hedaa dɔ nɛ. Woate ŋu agblɔ atikewɔmɔnu siwo nàte ŋu azã na wò eye woaɖo nyabiase ɖesiaɖe si anɔ asiwò la ŋu na wò.

Mina míaɖo ŋku nusi ŋu míeƒo nu tsoe dzi abe kpukpui ene (Take-Home Message) .

• Myotonic dystrophy (DM) nye domenyiŋusẽfianu ƒe dɔléle si koŋ nana lãmekawo gbɔdzɔna eye wògblẽna.
• Myotonia nye nɔnɔme si me wòsesẽna na lãmekawo be woaɖe dzi ɖi le wo zazã vɔ megbe.
• DM ƒomevi vevi eve li: DM1 kple DM2 . DM1 ƒe ƒomevi sue bubuwo hã li.
• Dzesiawo ate ŋu ato vovo le DM ƒe ƒomevi kple ame ɖeka yi ame gbɔ nu.
• Esia tso domenyiŋusẽfianu ƒe tɔtrɔ gbɔ.
• Wotoa domenyiŋusẽfianu dodokpɔ kple dodokpɔ bubuwo dzi dea dzesi dɔlélea.
• Togbɔ be womate ŋu adae bliboe o hã la, atikewɔmɔnu aɖewo li siwo ate ŋu akpɔ dzesiawo gbɔ eye woana agbenɔnɔ nanyo ɖe edzi.
• Ne ɖikeke aɖe le mewò le esia ŋu la, di atikewɔlawo ƒe aɖaŋuɖoɖo enumake. De dzesii kaba le vevie ŋutɔ.

Mele mɔ kpɔm be nyatakaka sia aɖe vi na wò. Nɔ lãmesẽ me!

` Myotonic Dystrophy, Lãmetsiŋusẽ ƒe Gbɔdzɔgbɔdzɔ, Domenyiŋusẽfianu ƒe Dɔlélewo, Myotonic Dystrophy, Lãmetsidɔlélewo, DM, Ahɔhɔ̃mekawo ƒe Dɔlélewo