Ðe nètsia dzi ɖe wò ʋumemi ŋu ɣesiaɣia? Ðewohĩ wò ɖɔkta ɖe gbe be woado ʋu kpɔ atsɔ akpɔ wò ʋumemi. Tsɔ kpe ɖe ʋumemi ƒe dodokpɔ si wowɔna ɖaa ŋu la, ɖɔktawo kafua dodokpɔ tɔxɛ aɖe ɣeaɖewoɣi be nàlé ŋku ɖe dzidɔ ƒe afɔku si le ŋuwò ŋu nyuie wu. Dodokpɔ mawo dometɔ ɖekae nye ApoB dodokpɔ. Esia ate ŋu ana nàkpɔe nyuie wu nenye be dzidɔ ate ŋu adze dziwò.
Nuka tututue nye Apolipoprotein B?
Kpuie ko la, apolipoprotein B-100, alo ApoB kpuie, nye protein si kpena ɖe ame ŋu wòtsɔa ami kple ʋumemi yia míaƒe ŋutilã katã me.
Bu eŋu ale. Ami kple ʋumemi siaa le vevie be míaƒe ŋutilã ƒe lãmenugbagbeviwo nanɔ lãmesẽ me ahawɔ lãmetsiŋusẽwo. Gake kuxiae nye be, wo dometɔ aɖeke melɔ̃na ɖe ʋua me o. Ele abe ami dede tsi me ene. Eyata, míehiã ‘nubablɛ’ tɔxɛ aɖe be wòatsɔ wo ayi ŋutilã ƒe akpawo katã. Nu mae nye nusi míeyɔna be lipoprotein . ApoB protein la nɔa lipoprotein ƒe akpa sia ƒe megbe eye wòwɔa dɔ abe ‘ʋukula’ si tsɔnɛ ene.
Vevietɔ wu la, ApoB protein la do ƒome kple lipoprotein ƒomevi siwo gblẽa nu le míaƒe ŋutilã ŋu, si woyɔna be "ʋumemi gbegblẽ." Esiawo ate ŋu aƒo ƒu ɖe míaƒe ʋukawo me, axe wo eye wòana dzidɔ nadze ame dzi.
| Lipoprotein "vɔ̃ɖi" ƒomevi siwo ApoB protein tsɔna | |
|---|---|
| Lipoprotein siwo ƒe kpekpeme le sue ŋutɔ | Lipoprotein siwo ƒe kpekpeme le sue ŋutɔ (VLDL) . |
| Lipoprotein siwo ƒe kpekpeme mede o | Lipoprotein siwo ƒe kpekpeme mede o (LDL) . |
| Lipoprotein siwo ƒe kpekpeme le titina | Lipoprotein siwo ƒe kpekpeme le titina (IDL) . |
ApoB protein la léna ɖe míaƒe ŋutilã ƒe lãmenugbagbeviwo ŋu eye wòkpena ɖe lipoprotein ƒe akpaa ŋu wògena ɖe lãmenugbagbevi la me. Emegbe wogbãnɛ, si wɔnɛ be ami kple ʋumemi dona ɖe ʋua me. Ne ʋumemi gbegblẽ sia ƒe agbɔsɔsɔ dzi ɖe edzi la, edzea gege ɖe ʋukawo me.
Nukatae wòhiã be mawɔ ApoB-100 dodokpɔ sia?
Lãmetsi si le lãmesẽ me ƒe ʋumemi si me ami ʋeʋĩ (LDL) le sue ŋutɔ . Gake agbɔsɔsɔ ma ƒe dzidziɖedzi nana dzidɔ ƒe afɔkua dzina ɖe edzi. Vevietɔ la, ApoB protein ɖeka le ʋumemi gbegblẽ ɖesiaɖe me.
Ema fia be ne míete ŋu dzidze ApoB protein ƒe agbɔsɔsɔ la, ate ŋu ana míakpɔ ʋumemi gbegblẽ siwo katã le míaƒe ʋu me ƒe agbɔsɔsɔme si sɔ pɛpɛpɛ ŋutɔ. Esia ate ŋu ana míakpɔ nɔnɔmetata si de pɛpɛpɛ wu ɣeaɖewoɣi wu míaƒe LDL ʋumemi ƒe agbɔsɔsɔ le mama dedie nu dzidzedze.
Susu geɖe tae wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàwɔ dodokpɔ sia ɖo:
- Ne dzidɔ le wò ƒomea me .
- Ne wokpɔ dzidɔ le ŋuwò xoxo la .
- Lé ŋku ɖe dzidɔ dada ƒe dzidzedzekpɔkpɔ ŋu .
- Ne ʋumemi alo triglycerides sɔ gbɔ ɖe mewò xoxo .
Zi geɖe la, wò ɖɔkta hã abia be woawɔ ʋumemi ƒe akpa si wozãna le mɔ vovovowo nu kpe ɖe ApoB dodokpɔa ŋu. Esia dzidzea nuwo abe ʋumemi ƒe agbɔsɔsɔ, triglyceride ƒe agbɔsɔsɔ, ʋumemi "nyui" (HDL), kple ʋumemi "vɔ̃ɖi" (LDL). Wotsɔ nyatakaka eve siawo ƒo ƒui be woatsɔ adzro wò dzidɔ ƒe afɔkua me bliboe.
Aleke nèwɔa dodokpɔ siae?
Ele bɔbɔe ŋutɔ. ApoB dodokpɔa nye ʋudodokpɔ bɔbɔe aɖe . Le dodokpɔxɔa me la, dɔnɔdzikpɔla alo mɔ̃ɖaŋudɔwɔla aɖe ɖea ʋu sue aɖe tso ʋuka aɖe si le wò alɔnu me.
Gake ɖo ŋku edzi be ne wò ɖɔkta de se be woawɔ dodokpɔ bubuwo abe ami ƒe dodokpɔ ene la, woate ŋu abia tso asiwò be nàtsi nu adɔ abe gaƒoƒo 12 ene . Esia fia be mele be nàɖu nu alo ano nu bubu aɖeke tsɔ wu tsi gaƒoƒo 12 hafi adoe kpɔ o. Wò ɖɔkta aɖo aɖaŋu na wò tso esia ŋu do ŋgɔ.
Nukae dodokpɔa ƒe nyatakakaa gblɔ?
Zi geɖe la, wodzidzea ApoB ƒe asixɔxɔwo le miligram ɖeka me (mg/dL).
| Metsonu | Gɔmesese kple nusiwo ate ŋu ahe esia vɛ |
|---|---|
| Asixɔxɔ si sɔ (Mede 90 mg/dL o) . | Lipoprotein gbegblẽ siwo le wò ʋu me la le lãmesẽ me. Dzidɔ ƒe afɔkua le sue. |
| Asixɔxɔ gã (High) . (si wu 110 mg/dL) . | Afɔku si le mewò be nàxɔ dzidɔ la lolo wu le mama dedie nu. Esia ate ŋu atso:
|
| Asixɔxɔ si le bɔbɔe (Low) . | Lãmesẽkuxi aɖewo hã ate ŋu ahe esia vɛ. Ðewohĩ ŋutilãa mate ŋu awɔ lipoproteins nyuie o. |
Ɣeaɖewoɣi la, wò ɖɔkta atsɔ wò ApoB (vɔ̃ɖi) ƒe agbɔsɔsɔ asɔ kple wò ApoA (protein si tsɔa ʋumemi nyui). Ne wò ApoB sɔ gbɔ wu wò ApoA la, ema hã nye dzesi be dzidɔ ƒe afɔku dzi ɖe edzi.
Ðe susu bubuwo li siwo tae dzidzenu siwo le nyatakakaa me ate ŋu atrɔ ɖoa?
Ẽ, keŋkeŋ. Tsɔ kpe ɖe atikewɔwɔ ƒe nɔnɔme siwo míeyɔ ɖe etame ŋu la, atike aɖewo siwo nèno kple agbenɔnɔ ƒe nɔnɔmewo hã ate ŋu akpɔ ŋusẽ ɖe wò ApoB ƒe agbɔsɔsɔ dzi.
- Lãmetsiŋusẽ ƒomeviwo (Androgens, Estrogens) .
- Ʋusɔgbɔdɔtikewo abe beta-blockers ene
- Atike siwo naa tsinyegoe me tsi
- Thyroid ƒe atike
- Statins, si nye atike ƒomevi aɖe si ɖea ʋumemi dzi kpɔtɔna
- Amekoko si wole ewɔm
- Kpekpeme dzi ɖeɖe kpɔtɔ alo eƒe dzidziɖedzi
- Nuɖuɖu si me ami sɔ gbɔ ɖo
- Vitamin kple kpeɖeŋutɔ aɖewo siwo nènona
Eyata hafi nàwɔ dodokpɔ sia la, ele vevie ŋutɔ be nàna wò ɖɔkta nanya nu tso atike, vitamin, kple kpeɖeŋutɔ ɖesiaɖe si nèzãna ŋu.
Azɔ hã, ɖo ŋku edzi be dzidzenu siawo siwo sɔ ate ŋu ato vovo vie le dodokpɔxɔ vovovowo, mɔnu si wozã, ƒe si nèxɔ, ŋutsu alo nyɔnu nyenye, kple lãmesẽ ŋutinya nu. Eyata be nànya nusi tututu wò nyatakakaa fia la, ƒo nu kple wò ɖɔkta. Aɖe eme na wò eme nakɔ.
Gbedasi si Wotsɔ Yi Aƒeme
- ApoB nye protein si tsɔa "ʋumemi gbegblẽ" (LDL, VLDL) ƒe akpa suesuesuewo le míaƒe ŋutilã me.
- ApoB dodokpɔa ate ŋu adzidze ʋumemi gbegblẽ siwo le ʋua me ƒe agbɔsɔsɔ pɛpɛpɛ. Esia le vevie ŋutɔ le dzidɔ ƒe afɔku me dzodzro me.
- ApoB ƒe agbɔsɔsɔ si dzi ɖe edzi nye dzesi be dzidɔ ƒe afɔku dzi ɖe edzi. Gake ne agbɔsɔsɔ si bɔbɔ le mɔ si mesɔ o nu ate ŋu afia lãmesẽkuxi bubuwo hã.
- Atike siwo nènona kple wò agbenɔnɔ hã ate ŋu akpɔ ŋusẽ ɖe dodokpɔ sia me tsonu dzi.
- Ame nyuitɔ kekeake kple ame ɖeka kolia si nàƒo nu tso gɔmesese vavãtɔ si le wò dodokpɔ ŋuti nyatakaka ŋu kple afɔɖeɖe siwo kplɔe ɖo si nàwɔ ŋue nye wò ɖɔkta.
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