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Gold injections for joint pain: Can a tiny dose of gold really soothe your rheumatoid arthritis?

Dr. Priya Sammani (MBBS)
Medically Reviewed by Dr. Priya Sammani (MBBS) ✓ Medically Reviewed
📅 Updated: Oct 20, 2026 • ⏱ 10 min read • Editorial Policy
Gold injections for joint pain: Can a tiny dose of gold really soothe your rheumatoid arthritis?
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Do you or someone you care about live with the sharp pain and swollen joints of rheumatoid arthritis? You might have heard your doctor mention a special injection containing real gold, often known by the medical name gold sodium thiomalate. Hearing that a treatment contains gold might sound surprising at first, but it has helped many people manage their joint symptoms for decades.

Living with chronic joint inflammation changes your daily routine in big and small ways. Simple tasks like opening a jar or buttoning a shirt can feel like major hurdles when your hands ache. Exploring every treatment option with your care team helps you find the right path toward feeling better and staying active.

Let us walk through everything you need to know about this unique medicine in plain, simple English. We will cover how it works, what you need to tell your medical team before starting, and what side effects require your immediate attention.

Key Takeaways.

  • What it does: Gold sodium thiomalate helps reduce joint swelling and slows down rheumatoid arthritis activity.
  • How it is given: A trained nurse or doctor administers this medicine as an injection directly into a muscle.
  • Ongoing checks: You will need regular blood and urine tests while on this treatment to monitor your safety.
  • Important safety: Always tell your doctor about all your medical conditions and other medicines before starting.
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What is gold sodium thiomalate and how does it work?

Simply put, gold sodium thiomalate is a specialized medicine designed to calm down the swelling and inflammation caused by rheumatoid arthritis in your body. Doctors use this treatment to help both adults and children who live with active rheumatoid arthritis.

However, it is important to understand one key detail about how this medicine works. While it reduces active inflammation and slows down disease progression, it cannot repair cartilage or bone damage that has already happened. Think of it as a protective shield that helps prevent future joint damage and keeps your current pain under control.

You might see this medicine referred to by its common brand name, Myochrysine. Your doctor may also prescribe it for other health reasons not listed here. If you have any questions about why your care team chose this treatment, always feel free to ask your doctor or pharmacist.

Things you must tell your medical team before starting.

Before you receive your first gold sodium thiomalate injection, sharing your complete health history with your doctor or nurse is extremely important. Certain health conditions or allergies mean this medicine might not be safe for you, or it may require extra careful monitoring.

Make sure to let your medical team know if you have any of the following health conditions:

  • Diabetes: If you take medicine or manage blood sugar levels for diabetes.
  • Heart disease: Any history of heart conditions or irregular heartbeats.
  • High blood pressure: If your blood pressure runs high.
  • Kidney disease: Any history of kidney problems or reduced kidney function.
  • Liver disease: If your liver health needs special management.
  • Blood disorders: Low levels of white blood cells, red blood cells, or platelets.
  • Lupus: If you have been diagnosed with systemic lupus erythematosus.
  • Allergies: Any past allergic reactions to gold sodium thiomalate, benzyl alcohol, other heavy metals, specific medicines, foods, dyes, or preservatives.
  • Pregnancy: If you are pregnant or planning to become pregnant soon.
  • Breastfeeding: If you are currently nursing a baby.

Giving your doctor this complete picture allows them to decide if this treatment is right for you. They can also set up the safest possible dosing schedule tailored just for your body.

How is this medicine given to you?

A medical professional always gives you this medicine as an injection into a muscle. You will receive these shots at a hospital clinic or doctor's office rather than taking them at home. Your care team handles the preparation and administration safely.

If a child needs this treatment, the doctor will discuss specific pediatric safety guidelines with the family. While doctors sometimes prescribe gold injections for young patients, careful supervision is always required.

Important: This medicine is prescribed specifically for you. Never share your treatment plan or medicines with anyone else under any circumstances.

What happens if you take too much?

If you suspect you received too much medicine or feel unwell after an injection, contact your local poison control center or head to the nearest emergency room right away. In the US, call 911 or reach out to Poison Control at 1-800-222-1222. In the UK, call 999 or NHS 111.

What if you miss a dose?

Keeping your scheduled appointment times is crucial for this treatment to work effectively. If something prevents you from making it to your clinic on your scheduled day, call your doctor's office right away to reschedule.

Your medical team will let you know exactly when to come in for your next injection and how to adjust your schedule safely. Do not try to double up on doses without guidance from your doctor.

Other substances that can interact with this medicine.

Certain medicines do not mix well with gold sodium thiomalate and can cause serious health issues. If you take either of the following medicines, you must not receive this injection:

  • Dimercaprol .
  • Penicillamine .

also, other treatments can interact with gold sodium thiomalate, including:

  • Cancer medicines: Drugs used to treat various forms of cancer.

This list does not cover every possible interaction. To keep you safe, give your doctor a complete list of every medicine you take, including prescription drugs, over-the-counter products, vitamins, and herbal supplements. Also mention if you smoke, drink alcohol, or use recreational substances, as these factors can influence your treatment.

Things to watch during your treatment.

Once you start receiving gold injections, you will need to visit your doctor regularly so they can check your progress. Your care team will also order routine lab work, such as blood and urine tests, to make sure the medicine works properly and does not harm your organs.

  • Skin rashes: Watch your skin closely. If you notice any new rash, redness, or itching, tell your doctor right away.
  • Sun sensitivity: This medicine can make your skin much more sensitive to sunlight. Try to limit your time in direct sunlight. When you go outside, wear protective clothing, put on a hat, and apply a broad-spectrum sunscreen. Avoid artificial sun lamps, tanning beds, and tanning booths completely.

Possible side effects to watch for.

Like all medicines, gold sodium thiomalate can cause side effects. Some reactions are mild and go away on their own. This others are serious and require urgent medical care.

Side effects to report to your doctor right away:.

If you notice any of these signs, contact your doctor or seek medical help as soon as possible:

  • Allergic reactions: Skin rash, itching, hives, or swelling of your face, lips, or tongue.
  • Trouble breathing or shortness of breath.
  • Changes in your vision.
  • Fast or irregular heartbeat.
  • Feeling dizzy, lightheaded, or fainting.
  • Fever, chills, or a sore throat.
  • Seeing or hearing things that are not real (hallucinations) or feeling confused.
  • Loss of appetite or nausea.
  • A strange metallic taste in your mouth.
  • Sores inside your mouth or on your lips.
  • Pain, numbness, or tingling in your hands and feet.
  • Severe skin redness, blistering, peeling, or sores inside your mouth.
  • Stomach cramps or sharp abdominal pain.
  • Trouble urinating or noticeable changes in the amount of urine you produce.
  • Unusual bleeding or bruising under your skin.
  • Extreme tiredness or lack of energy.
  • Yellowing of your skin or the whites of your eyes (jaundice).

Mild side effects that usually do not need emergency care:.

These symptoms are common and often mild, but let your doctor know if they continue or bother you:

  • General muscle aches or soreness.
  • Mild diarrhea or loose stools.
  • Temporary hair thinning or hair loss.
  • Mild headaches.

This list does not include every possible side effect. If you experience any other unusual symptoms, mention them to your doctor or nurse during your next visit.

How to store your medicine.

Because doctors give this injection at a clinic or hospital, you do not need to store or keep this medicine at home. Your medical team handles all preparation, storage, and disposal safely.

💡 Take-home message.

We have covered a lot of important details about gold sodium thiomalate injections. Here is a quick review of the main points to keep in mind:

  • This medicine helps control joint swelling and inflammation caused by rheumatoid arthritis.
  • It protects your joints from further damage, but it cannot reverse existing joint injury.
  • Always share your complete medical history, allergies, and current medicines with your doctor.
  • Medical staff give you the injection at a clinic or hospital setting.
  • Never miss your scheduled lab tests and doctor appointments.
  • Protect your skin from strong sunlight and tanning beds.
  • Report any serious side effects to your healthcare team right away.
❓ FAQ

Frequently Asked Medical Questions (FAQ)

Evidence-based clinical answers to common patient questions

Why do doctors use gold sodium thiomalate injections?

Doctors prescribe this medicine to treat active rheumatoid arthritis. It helps reduce painful joint swelling, calms inflammation, and slows down long-term joint damage when other medicines do not work well enough.

How is this treatment given and monitored?

A nurse or doctor gives the medicine as an intramuscular injection at a clinic or hospital. Because gold can sometimes cause toxicity, you will need regular blood and urine tests to monitor your kidney function and blood cell counts.

Can these injections reverse damage already in my joints?

No, gold sodium thiomalate cannot repair cartilage or bone damage that has already occurred before you started treatment. Instead, it acts to protect your joints by preventing future damage and reducing active inflammation.

What precautions should I take regarding sunlight?

This medicine can make your skin very sensitive to light. You should limit your time in direct sunlight, wear protective clothing, apply sunscreen, and avoid tanning beds or sun lamps completely.

When should I call my doctor about side effects?

Call your doctor right away if you notice signs of an allergic reaction, skin rashes, mouth sores, unusual bleeding, yellowing of your skin, or severe fatigue. Quick communication helps prevent minor side effects from turning serious.

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Verified Scientific & Medical References (PubMed / WHO)

✓ Peer-Reviewed Sources
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