What you need to know about Lefamulin tablets

What you need to know about Lefamulin tablets

You may have been prescribed an antibiotic by your doctor to treat a bacterial infection. Lefamulin is an antibiotic used to treat certain types of bacterial infections. It belongs to a class of antibiotics called pleuromutilins. The most important thing to remember is that this medicine does not work at all for viral infections, such as the common cold or flu.

Things you need to tell your doctor before taking this medicine

It is very important that your doctor is fully aware of your health condition before prescribing Lefamulin. Therefore, be sure to tell your doctor if you have any of the following conditions:

  • Heartbeat irregularities: Tell us if you have had an unusually fast or irregular heartbeat before.
  • Kidney Disease: If you have any kidney-related condition.
  • Liver Disease: If there is any problem or condition related to liver function.
  • Allergies: You should tell your doctor if you have had an allergic reaction to this medicine, other antibiotics, other medicines, foods, dyes or preservatives.
  • Pregnancy: If you are pregnant or trying to get pregnant, tell us about it.
  • Breastfeeding: If you are a mother who is breastfeeding your child, inform your doctor about this as well.

How should I use the medicine?

It is very important to follow the instructions exactly when using this medicine.

  • How to take: Swallow this tablet with a full glass of water. Do not break, crush, or chew the tablet. Swallow it whole.
  • Timing: This is the most important thing. This medicine should be taken on an empty stomach . Simply put, it should be taken at least one hour before or two hours after a meal. Do not take it with food.
  • Take it on time: Take the medicine at the prescribed time and at the prescribed intervals as prescribed by your doctor. Do not take it too often or skip doses.
  • Complete the course: Even if you feel better, be sure to finish all of the medication prescribed by your doctor for the full number of days. Do not skip doses or stop taking the medication. Doing so may cause the infection to return.

If you are giving this medicine to children, you should talk to a pediatrician about it. Special care may be needed.

What if I take too much medicine? (Overdosage)

If you think you have taken more medicine than you think, immediately call the National Poisons Information Centre at the Colombo National Hospital . Or go to the Emergency Treatment Unit (ETU) of the nearest hospital.

Important note: This medicine has been prescribed for you only. Never share this medicine with anyone else.

What to do if you miss a dose of medicine?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Never take a double dose to make up for a missed dose.

Other drugs that may interact with this medicine (Drug Interactions)

Some medications can interact with lefamulin and cause problems. So, tell your doctor about all the medications you take, including vitamins and herbal remedies.

Drug type Description
Do not take this medicine with any other medicine.
Cisapride A medicine for stomach problems.
Dronedarone A medication for heart rhythm disorders.
Pimozide A medicine for mental illness.
Thioridazine A medicine for mental illness.
Other drugs that may interact with this medicine (inform your doctor)
Alprazolam, Midazolam Medications for anxiety or insomnia.
Birth control pills Medicines used for family planning.
Diltiazem, Verapamil For high blood pressure or heart disease.
Simvastatin To reduce blood cholesterol.
Drugs that prolong the QT interval Other medications that can cause heart rhythm abnormalities.

This list is not complete, so it's best to tell your doctor about all the medications you take.

Things to keep in mind when taking medication

  • If your symptoms do not improve, or even worsen, tell your doctor.
  • Birth control: This medication may make birth control pills less effective. Therefore, talk to your doctor about using another form of birth control (such as condoms) while taking this medication and for 2 days after stopping the medication.
  • Pregnancy: Do not become pregnant while taking this medicine. Avoid becoming pregnant for at least 2 days after taking the last dose of the medicine. If you accidentally become pregnant, tell your doctor immediately.

Special attention for diarrhea: If you have diarrhea for more than 2 days, or if your diarrhea is severe and watery, do not self-medicate with over-the-counter medication. Talk to your doctor immediately.

Side effects that may occur due to medication

Like any medicine, lefamulin can cause some side effects. Some are serious, while others are common.

Side effect Description
Serious side effects that should be reported to the doctor immediately
Allergic Reactions Skin rash, hives, swelling of the face, lips, or tongue.
Severe diarrhea If you have bloody or watery diarrhea.
Changes in heart rate Chest pain, dizziness, fast or irregular heartbeat, fainting, difficulty breathing.
Symptoms of liver damage Dark yellow or brown urine, yellowing of the eyes or skin, pain in the upper right part of the stomach, loss of appetite, nausea, and feeling lethargic.
Side effects that are usually not serious, but should be reported to the doctor if they persist
Normal diarrhea Flatulence.
Headache Headache.
Nausea, vomiting Nausea and vomiting.
Insomnia Difficulty sleeping at night.

This list does not include all possible side effects. If you experience anything unusual, please contact your doctor for advice.

How do you store your medicine?

  • Keep away from children.
  • Store at room temperature (between 15 and 30 degrees Celsius).
  • Throw away expired medicine.

Take-Home Message

  • Lefamulin is an antibiotic used to treat bacterial infections. It does not work for viral infections such as colds and flu.
  • This medicine should always be taken on an empty stomach (one hour before or two hours after a meal).
  • Take the entire dose of medicine prescribed by the doctor for the prescribed number of days. Do not stop halfway.
  • Be sure to tell your doctor about all other medications you are taking and any other medical conditions you may have.
  • If you experience any serious side effects, such as severe diarrhea, allergic reactions, or changes in heart rate, seek medical advice immediately.

Lefamulin, antibiotic, Xenleta, bacterial infection, side effects, medication

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