Sometimes we can suddenly have a big fit, or we feel very scared and anxious, like before a major operation, right? Maybe a doctor has told you or someone you know about a medicine called `Lorazepam`. Today we are going to talk about this medicine, which is often given as an injection, to help in such times. There is nothing to be afraid of, let's understand everything simply.
What is Lorazepam? What does it do?
Simply put, Lorazepam is a drug that calms your nervous system down and reduces its activity. It belongs to a class of drugs called ``Benzodiazepines.'' You may be familiar with it under the brand name ``Ativan.''
Now look, this is mainly used in two situations:
1. Control seizures: If the seizures keep coming, or if the seizures are difficult to stop, doctors prescribe this medication.
2. Reduce Anxiety: This is used to reduce anxiety and stress, especially before surgery. It can sometimes be given before other medical tests.
This medicine works by affecting the activity of certain chemicals in the brain (to be precise, ``Neurotransmitters'') and slowing down the nervous system. That's why things like anxiety and fits are controlled. Do you understand?
What are the things I need to tell the doctor before using this medicine?
This is very important . Before giving you Lorazepam, it is essential that your doctor is well aware of your health condition. Because, people with certain diseases need to be very careful when giving this medicine, or it may not be suitable for them.
If you have any of these things, it's definitely a good idea to tell your doctor .
- Glaucoma condition: If you have glaucoma, a condition that causes increased pressure in the eyes, you should disclose it.
- If you have ever been addicted to drugs or alcohol: If you have ever used drugs or been addicted to alcohol, it is very important to tell your doctor about it, as the effects of these things may change with this medicine.
- Kidney disease: If your kidneys are not working properly, this medicine may affect the way it is excreted from your body. So if you have any kidney problems, tell your doctor.
- Liver disease: If the liver function is low, that will also affect the duration of this medicine in the body. So that should be mentioned as well.
- Lung or breathing problems: If you have a lung disease like asthma or any other breathing problem, tell your doctor, as this medicine can sometimes make it a little difficult to breathe.
- Mental illness: If you are suffering from other mental illnesses (e.g. depression), inform your doctor about that as well.
- Myasthenia Gravis: This is a disease that causes muscle weakness. Lorazepam should be used with caution in people with this disease.
- Parkinson's Disease: If you have this disease, tell us about it too.
- Suicidal thoughts or attempts: If you or someone in your family has ever had suicidal thoughts or attempted suicide, it is important to tell them . This medicine can sometimes make such thoughts worse.
- If you have an allergy to Lorazepam or other medicines, foods, dyes, or preservatives: Tell your doctor if you have had an allergic reaction to this medicine in the past, or if you are allergic to anything else.
- If you are pregnant or trying to get pregnant: This is very important. Your doctor should decide whether to give this medicine during pregnancy.
- If you are a breastfeeding mother (Breast-feeding): This medicine can pass to your baby through breast milk. Therefore, if you are breastfeeding, you should also mention that.
Remember, it's for your own safety to tell the doctor without hiding these things.
How do you use this medicine?
Lorazepam is not a medication that you can usually take home. It is given as an injection . It is either injected into a muscle or into a vein . It is given in a hospital or clinic under medical supervision.
Special care should be taken when giving this medicine to young children . Your doctor will explain this to you.
What to do if you take too much? (Overdosage)
Since this is given in a hospital, there is no need to worry about an overdose. However, if you think you may have overdosed, you should immediately contact a poison control center or emergency room .
Important: This medicine is for you only. Never share this medicine with anyone else.
What if I miss a dose?
Since this medication is given under the supervision of a doctor, missing a dose is not relevant.
Are there any other medications that should not be used with Lorazepam, or that I should be careful with?
Yes, this is also a very important point. If you are using other medications, it is imperative to tell your doctor about it. Because some medications can cause adverse effects (interactions) when combined with Lorazepam.
Never take Lorazepam with these medications:
- Some narcotic medications for cough
- Sodium oxybate
Lorazepam can interact with the following medications, so be sure to tell your doctor if you are taking them:
- Alcohol: Taking this medication with alcohol can increase drowsiness, dizziness, and difficulty breathing.
- Antihistamines for allergies, coughs, and colds: Taking these can also increase drowsiness.
- Certain medications for anxiety or sleep
- Some medications for depression: For example, medications like `Amitriptyline`, `Fluoxetine`, `Sertraline`.
- Some medications given for fits: For example, medications like `Carbamazepine`, `Phenobarbital`, `Phenytoin`, `Primidone`.
- General anesthetics: Examples include `Lidocaine`, `Pramoxine`, `Tetracaine`.
- MAOI medications: Examples include `Carbex`, `Eldepryl`, `Marplan`, `Nardil`, and `Parnate`.
- Medications that relax muscles for surgery
- Narcotic medications for pain
- Phenothiazines: Examples include Chlorpromazine, Mesoridazine, Prochlorperazine, and Thioridazine.
This list may not include all medications. Therefore, tell your doctor about all medications you take (including vitamins, herbal remedies, and supplements), and if you smoke, drink alcohol, or use other drugs. Some things can interact with your medication.
What should I be careful about when taking this medicine?
When taking Lorazepam, it's a good idea to pay attention to changes in your body.
- If your symptoms (e.g., fits, restlessness) do not improve, or if they seem to get worse , tell your doctor immediately.
- You may feel drowsy or dizzy . Do not drive, operate machinery, or do anything else that requires alertness until you know exactly how this medicine affects you.
- Don't stand up or sit down suddenly. This will reduce the chance of dizziness and falling, especially if you are elderly.
- Do not use alcohol. Alcohol can change the effects of this medicine and may increase side effects.
- If you are taking other medicines that make you sleepy (for example, some cough medicines, allergy medicines), you may become more sleepy. So tell your doctor about all the medicines you are taking. Take only the amount of medicine your doctor tells you to take. Never take more medicine than your doctor tells you to take.
- If you have difficulty breathing or feel unusually drowsy , call emergency services immediately.
What are the possible side effects?
Like any medicine, Lorazepam can cause some side effects. However, not everyone gets them. Only some people get them.
If you experience any of these side effects, tell your doctor as soon as possible:
- Allergic reactions: skin rash, itching, hives, swelling of the face, lips, tongue, or throat. If this happens, seek immediate medical attention.
- Central nervous system depression (CNS depression): Slow or shallow breathing, difficulty breathing, fainting, dizziness, confusion, difficulty staying awake.
- Thoughts of suicide or harming yourself: worsening of mood, increased depression. If you experience any of these, tell your doctor immediately.
These side effects are usually not dangerous, but if they persist or become bothersome, tell your doctor:
- Dizziness
- Drowsiness
- Headache
- Nausea
- Vomiting
This list may not include all side effects. If you notice anything unusual, talk to your doctor about it.
Where should I keep my medication?
This is not something you should worry about. Because, you are not allowed to take the Lorazepam injection home . It is only given to you in a hospital or clinic . So you don't have to worry about keeping the medicine.
Finally, things to remember (Take-Home Message)
Okay, so we've talked a lot about Lorazepam, haven't we? In short, it's an injectable medication that's used for fits and major anxiety.
- The most important thing is to tell the doctor every detail about your health condition (especially the illnesses we discussed earlier, other medications you are taking, and allergies).
- This medicine is only given under the supervision of a doctor.
- Be careful as it can cause drowsiness and dizziness. Do not drive or drink alcohol.
- If you notice anything unusual or a new side effect, tell your doctor immediately.
Don't be afraid, the doctors are using this medicine to help you. If you have any questions or if there is anything you don't understand, ask the doctor or pharmacist.
` Lorazepam, Ativan, Benzodiazepines, Seizure treatment, Anxiety medication, Injection side effects, Drug interactions


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