What you need to know about steroid injections (Methylprednisolone)

What you need to know about steroid injections (Methylprednisolone)

You may remember that sometimes when you have a severe allergy, a joint ache, or a severe asthma attack, your doctor will prescribe you a special injection. Many people are a little afraid of these "steroid" injections. But in fact, if used correctly, these are very important drugs that can help save lives. Today we are talking about one such powerful drug, the methylprednisolone injection.

Simply put, what is Methylprednisolone?

Methylprednisolone is a drug that belongs to the group of drugs called "Steroids". Imagine that our body naturally produces a hormone called "Cortisol". This hormone is what gives our body the strength to cope with things like stress, illness, and injury. So, Methylprednisolone is a powerful synthetic drug that is similar to the action of this cortisol hormone.

This has two main functions:

1. Reducing inflammation in the body: Imagine that one of your joints is swollen, red, and painful. That means there is inflammation there. This medicine controls that inflammation.

2. Controlling the unwanted activity of the immune system: Sometimes our own defense system, that is, the immune system, becomes unnecessarily active and starts damaging our own body. An example is diseases like arthritis. This medicine controls that unwanted activity.

Therefore, this injection is used to treat a number of diseases, such as asthma, severe allergies, arthritis, and inflammatory bowel diseases.

Things you should definitely tell your doctor before taking this medicine:

This is very important . Before giving you this injection, it is essential that your doctor knows your complete health history. This medicine may interact with certain medical conditions. See the table below.

If you have these conditions... Why is it important to tell the doctor?
Diabetes Steroid medications can increase blood sugar levels, so you may need to adjust the dosage of your diabetes medication.
High blood pressure This medicine may further increase blood pressure.
Heart disease There is a small chance that heart conditions will worsen.
An infectious condition (e.g., chickenpox, herpes) Because steroids weaken the immune system, existing infections can worsen.
Stomach or intestinal ulcers/problems This medicine may slightly increase the risk of stomach ulcers.
Liver disease, thyroid problems, glaucoma If these conditions are present, the effectiveness of the medication may change.
If you are pregnant, trying to get pregnant, or are a breastfeeding mother The doctor should be especially careful about administering this medication in such cases.
If you have allergies to other medications, foods, or substances This is important to know if you are allergic to this medicine or any of its ingredients.

The most important thing is to give your doctor a complete list of all medications you are taking (including vitamins and herbal remedies) and your medical history.

How do you use this medicine?

This is not a medicine you can take home and inject. Methylprednisolone injection is given into your joint, muscle, or other tissue by a doctor or trained nurse in a hospital or clinic . So you don't have to worry about missing a dose.

If you suspect that you have accidentally overdosed on this medicine, immediately call the National Poisons Information Centre at the Colombo National Hospital . Or go to the Emergency Treatment Unit (ETU) of the nearest hospital.

Other drugs that may interact with this medicine (Drug Interactions)

Some medications can cause problems when taken with methylprednisolone, so it is very important to tell your doctor about all the medications you are taking.

  • Medications that should never be taken together: Some live virus vaccines and medications like Mifepristone should not be taken together.
  • Other medications that may cause problems: Painkillers (NSAIDs - e.g. Ibuprofen), aspirin, some diabetes medications, antifungals (e.g. Ketoconazole), the blood thinner Warfarin, some antibiotics, and birth control pills can interact with this medication.

Your doctor will review your medication list and make any necessary changes.

Things to be careful about while taking the medicine

Be aware of symptoms.

If your symptoms do not improve or worsen, tell your doctor . Never stop taking steroids suddenly without your doctor's advice. Doing so may cause a serious reaction.

Be careful of infections.

While taking this medicine, your immunity will be slightly reduced, so you are more likely to catch diseases.

  • Stay away from people who have illnesses like chickenpox and measles.
  • If you develop any symptoms such as fever, cough, chills, or body aches, tell your doctor .
  • If you get a wound, take care of it if it doesn't heal quickly.

Other points

  • If you have diabetes, check your blood sugar levels regularly, as this medicine may increase your blood sugar levels.
  • If you experience any changes in your vision (such as blurred vision), tell your doctor immediately.
  • If you use this medicine for a long time , you may be at risk of developing osteoporosis. Talk to your doctor about this as well.

What are the possible side effects?

Like any medicine, methylprednisolone can cause side effects. Not everyone gets them, but it's important to be aware of them.

Type of side effect Symptoms
Side effects that should be reported to your doctor immediately
Severe allergic reactions Skin rash, itching, swelling of the face, lips, tongue, difficulty breathing.
Cushing's syndrome Fat deposits around the stomach, neck, and upper back, pink/purple streaks on the skin, and thin skin that bruises easily.
Increased blood sugar (Hyperglycemia) Excessive thirst, frequent urination, unusual tiredness, blurred vision.
Increased blood pressure Symptoms such as headache and dizziness.
Mental and behavioral changes Unnecessary anger, restlessness, mental confusion, depression, suicidal thoughts.
Stomach bleeding Black or tarry stools, vomiting of coffee grounds.
Swelling of the ankles, hands, or feet It can occur due to fluid retention in the body.
Things that are usually not serious, but should be reported to the doctor if they persist
Minor side effects Acne, increased appetite, weight gain, headaches, nausea, insomnia, general discomfort and fatigue.

Take-Home Message

  • Methylprednisolone is a powerful steroid medication that should only be used under the supervision of a doctor.
  • Before taking this medicine, tell your doctor clearly about all your medical conditions and all the medications you are taking .
  • Protect yourself from infections and take care of things like blood sugar levels and blood pressure while taking the medication.
  • If any severe side effects occur, seek medical advice immediately.
  • Never stop steroid treatment suddenly without your doctor's advice.

Methylprednisolone, steroid, steroid injection, Depo-Medrol, side effects, inflammation, allergies, asthma, diabetes

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