Sometimes your doctor will prescribe you a medication, one of which is methylprednisolone. Maybe it's for your arthritis, joint pain, or a severe allergy. Many people get scared when they hear the word 'steroid'. But if you use it correctly, according to your doctor's instructions, it is a very useful medication that can help control many conditions. So, let's talk about it in detail today.
What exactly is methylprednisolone?
Simply put, this is a drug that belongs to a class of drugs called steroids. It does several important things in our body.
- Reduces inflammation in the body: Inflammation, simply put, is swelling, redness, and pain in a part of the body. This medicine controls these conditions.
- Controls an overactive immune system: Our immune system is like an army that protects our body from diseases. But sometimes this army becomes overactive and starts attacking our own body cells. This medicine controls that overactivity.
- Acts as a natural hormone in the body: Our body has a hormone called cortisol. This is very important in controlling the body's response to things like stress and illness. Sometimes when the body's production of this hormone decreases, this medicine is given instead.
For these reasons, doctors recommend this medicine as a treatment for a number of diseases, including asthma, severe allergic reactions, arthritis, some skin diseases, and inflammatory bowel diseases.
Things you need to tell your doctor before taking medicine
It is very important that your doctor knows your complete health history before prescribing this medication to you. Be sure to tell them about any of the following conditions, especially if you have any:
- If you have Cushing's syndrome
- If you have eye diseases or vision problems
- If you have diabetes
- If you have glaucoma
- If you have heart disease
- If you have high blood pressure
- If you currently have any infection, including a viral infection like chickenpox or herpes
- If you have liver disease
- If you have any mental illness
- If you have a neurological disease called myasthenia gravis
- If you have a bone thinning disease such as osteoporosis
- If you have recently received a vaccine or are scheduled to receive one in the future
- If you have had seizures before
- If you have stomach or intestinal problems (e.g. ulcers)
- If you have a thyroid condition
- If you have an allergic reaction to methylprednisolone or any other medicine, food, or dye.
- If you are pregnant or expecting a baby
- If you are a breastfeeding mother
How should I use this medicine?
It is very important to follow your doctor's instructions exactly when using this medicine.
- Take these pills by mouth with a glass of water.
- It is best to take it after meals. This reduces the risk of stomach irritation and gastritis.
- If you only have to drink it once a day, drinking it in the morning is better suited to the body's natural hormonal activity.
- Do not drink more than the amount prescribed by your doctor.
Very important: Even if you feel better, do not stop taking this medicine suddenly without consulting your doctor. Doing so may cause a serious reaction. If you do stop taking the medicine, do so by gradually reducing the dose as your doctor tells you.
What if I take too much medicine?
If you think you have taken too much of this medicine, immediately call the National Poisons Information Centre at the Colombo National Hospital, or go to the Emergency Treatment Unit (ETU) of the nearest hospital.
What to do if you miss a dose of medication?
If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose (e.g., it is only a few hours away), skip the missed dose and take your next dose as usual. Never take a double dose to make up for a forgotten dose without first checking with your doctor. If in doubt, ask your doctor.
Other things that may interact with this medicine
Methylprednisolone can interact with other medications, so tell your doctor about all the medications you are taking (including vitamins and herbal remedies).
| Drug Interactions | |
|---|---|
| These should not be taken together. |
|
| Other medications that may cause problems |
|
What are the possible side effects of taking the medicine?
Like any medicine, methylprednisolone can cause side effects in some people. Some of these are serious, while others are common. It is important to be aware of these.
| Notify your doctor immediately! | |
|---|---|
| Side effect | Explanation |
| Allergic reactions | Skin rash, itching, swelling of the face, lips, tongue. |
| Cushing's syndrome | Fat deposits around the stomach, neck, and face, thinning skin, easy bruising, and pink/purple streaks on the skin. |
| Increased blood sugar (Hyperglycemia) | Excessive thirst, frequent urination, lethargy, blurred vision. |
| Increased blood pressure | Symptoms such as headache and dizziness. |
| Signs of infection | Fever, chills, cough, sore throat, non-healing wounds. |
| Mental changes | Anxiety, agitation, depression, suicidal thoughts. |
| Stomach bleeding | Black, tarry stools, vomit that looks like coffee grounds. |
| Swelling of ankles, hands, and feet | It can occur due to fluid retention in the body. |
| Side effects that are usually not serious, but should be reported to the doctor if they persist | |
|---|---|
| Acne | Headache |
| Increased appetite | Nausea |
| Insomnia | Weight gain |
Take-Home Message
- Methylprednisolone is a powerful medication that should be used only as directed by a doctor. Therefore, never use it based on the recommendations of others.
- Never stop taking your medication suddenly without consulting your doctor. It can be very dangerous.
- Be sure to tell your doctor about any other medications you are taking and any other illnesses you have.
- Protect yourself from infections while taking the medication, and monitor your blood sugar levels, especially if you have diabetes.
- If you notice any signs of a serious side effect (e.g., vomit that looks like coffee grounds, black stools), seek medical advice immediately.


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