Sometimes the pain we experience can be so severe that it cannot be controlled with ordinary painkillers. Imagine, for this kind of pain that comes after a major surgery, or due to another serious medical condition, doctors use a special painkiller. One such powerful painkiller injection is called Oliceridine. This is not a commonly prescribed medication, which is why it is very important to know exactly what it is.
What is this Oliceridine?
Simply put, Oliceridine is a very powerful painkiller . It belongs to a class of painkillers called opioids. This medicine works by blocking pain signals from reaching your brain. This means it reduces the sensation of pain.
This medication is usually only recommended when other painkillers are not enough to control the pain, or when the body cannot tolerate other painkillers. It is given as an injection into a vein, under medical supervision, in a hospital or clinic .
Things you need to tell your doctor before taking this medicine
Before giving you this medicine, your doctor will need to know your complete health history. This is because using this medicine with certain medical conditions can be risky. Therefore, if you have any of the conditions listed below, be sure to tell your doctor about it.
| Your health condition | Why should you inform the doctor? |
|---|---|
| Brain tumor or head injury | This medicine can increase pressure on the brain and make the condition more serious. |
| Drug or alcohol addiction | Opioids are a class of drugs that carry a risk of addiction. |
| Lung or breathing diseases such as asthma | This can slow breathing, which can increase breathing difficulties. |
| Liver disease | Because the liver processes medications, the effects of the medication may change in cases of liver disease. |
| Heart disease | Some heart conditions can be affected. |
| Seizures | The risk of seizures may increase. |
| Stomach or intestinal problems | It can aggravate conditions such as constipation. |
| If you are pregnant, trying to get pregnant, or are a breastfeeding mother | This medicine can affect the mother and the baby in the womb. |
| If you have allergies to other medications, foods, or substances | It is essential to inform this to prevent allergic reactions. |
What to do if you overdose?
Because this is given in a hospital, the medical staff is very careful about this. However, if you or someone you know thinks you have taken too much of this medicine, such as if your breathing is very slow or you are losing consciousness, it is an emergency.
Do not panic immediately and inform the medical staff. Usually, in such a situation, you can call the National Poison Information Center at the National Hospital , or you should immediately inform the hospital's Emergency Treatment Unit (ETU) .
Be aware of these things when taking medication.
Your condition will be monitored regularly by doctors and nurses while you are taking this medicine, but it is important for you to be aware of these things.
Take care of the pain.
You may need to take less of this medicine for a while to control your pain. This is called tolerance . This means your body is getting used to the medicine. This is not an addiction. Tolerance is normal when you take painkillers for a long time. If your pain does not go away, gets worse, or you have a new type of pain, tell your doctor.
Do not stop taking the medicine suddenly.
Once your body gets used to this medication, you may experience withdrawal symptoms if you stop taking it suddenly. Therefore, if your doctor feels the need to stop taking this medication, he or she will gradually reduce the dose and give your body time to adjust.
Drowsiness and dizziness
This medicine may make you feel very sleepy and dizzy. Therefore, do not drive or operate machinery until the effects of this medicine wear off. Especially if you are an elderly person, be careful when getting up from a sitting position or getting out of bed. Otherwise, you may feel dizzy and fall.
Constipation
A common side effect of opioid painkillers is constipation. This means that bowel movements become irregular and difficult. Try to have a bowel movement every two to three days if possible. If you have not had a bowel movement for more than three days, tell your doctor or nurse.
Dry mouth
Dry mouth is another side effect. This can be controlled by chewing sugar-free gum and drinking plenty of water.
What side effects can be expected?
Like any medicine, Oliceridine can cause side effects. Some are serious, while others are common.
| Nature of the side effect | Features to expect |
|---|---|
| Serious side effects that should be reported to the doctor immediately | |
| Allergic reactions | Skin rash, itching, swelling of the face, lips, tongue or throat. |
| Central nervous system depression (CNS depression) | Breathing that is very slow or shallow, difficulty breathing, excessive sleepiness, confusion. |
| Low blood pressure | Dizziness, blue eyes, feeling faint. |
| Low adrenal gland function | Nausea, vomiting, loss of appetite, unusual tiredness, dizziness. |
| Side effects that are usually not serious, but should be reported to the doctor if they persist | |
| Constipation | Difficulty passing stool. |
| Dizziness & Drowsiness | Feeling dizzy, constantly sleepy. |
| Dry mouth | Drooling in the mouth. |
| Headache, nausea, vomiting | These usually occur in the early stages and then subside. |
Can this medicine interact with other medications?
Yes, absolutely. Oliceridine is a drug that can interact with many other medications. Therefore, it is important to tell your doctor about all the prescription medications, vitamins, herbal remedies, and supplements you are taking. It can interact especially with the following classes of medications:
- Medication for anxiety or sleep
- Some medications for depression
- Medicines for allergies, coughs, and colds (Antihistamines)
- Medicines for fungal infections
- Some types of antibiotics
- Medicine for seizures
- Medicines given to relax muscles during surgery
- Other strong painkillers
Take-Home Message
- Oliceridine is a powerful intravenous painkiller that is only given in a hospital setting for very severe pain.
- It is imperative to inform your doctor about all your medical conditions and all other medications you are taking.
- Avoid activities that require alertness as this medication may cause drowsiness and dizziness. Constipation is common.
- If you notice any serious side effects, such as difficulty breathing or severe allergic reactions, notify medical staff immediately.
- Avoid stopping this medication suddenly for any reason without medical advice.
- This medicine is for you only. Never share it with anyone else.
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