Do you also have epilepsy, or what we usually call a seizure disorder? Or has a family member or friend had to undergo treatment for this condition? If so, your doctor may have prescribed you a pill called Perampanel. You may have many questions about this medication. "What will happen with this?", "What precautions should you take while using it?" Things like that. So, today we will talk about everything about this Perampanel medication, in simple language that you can understand.
What exactly is Perampanel?
Simply put, Perampanel is a medicine that is used to prevent and control seizures or fits caused by epilepsy. There are nerve cells in our brain. Sometimes a fit occurs because these nerve cells are unnecessarily and excessively stimulated. Perampanel works by calming the overactive nerve cells. Through this, the occurrence of fits is controlled. In our country, this medicine can be seen under the brand name `Fycompa`.
Things you need to tell your doctor before starting medication
Before you are given this medicine, it is extremely important to give your doctor a complete description of your health condition. Because that information will determine whether this medicine is suitable for you, and at what dosage. Don't forget to tell them about these things in particular:
- Mental health issues: If you or anyone in your family has or has had a mental illness such as depression, bipolar disorder, or if you have ever had thoughts of suicide, you should also tell them about it.
- Other illnesses: If you have liver disease or kidney disease.
- Alcohol and drugs: If you are a regular drinker or have an addiction to other drugs.
- Allergies: If you have an allergy to this Perampanel medicine or any other medicine, food, or dye.
- Pregnancy and breastfeeding: If you are pregnant, trying to become pregnant, or breastfeeding, it is imperative that you inform your doctor before starting this medication.
How exactly do I use this medicine?
Swallow this tablet with a glass of water. Take the medicine at the prescribed time, as directed by your doctor. You can take it before or after meals. However, if you experience stomach upset, it is better to take it with food.
The most important thing is, do not stop taking this medication suddenly for any reason without your doctor's advice. Doing so may increase the frequency of your fits or make your condition worse.
Usually, when starting this type of medication, it can take a few weeks or months to find a stable dose that suits your body. During that time, the doctor will gradually change the dose. Therefore, it is very important to follow the doctor's instructions.
What to do if you miss a dose of medication?
If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Never take a double dose.
What if you take too much medicine? (Overdose)
If you think you have accidentally taken more than the prescribed dose of this medicine, call the National Poisons Information Centre at the Colombo National Hospital immediately. Or go to the Emergency Department (ETU) of the nearest hospital. Do not take this lightly.
Other things that may interact with Perampanel
Perampanel is a medication that can interact with some other medications and substances. Therefore, it is important to tell your doctor about all the medications you are taking (including vitamins and herbal remedies). The table below shows some of the things that may interact with Perampanel.
| Drug/substance type | Things to consider |
|---|---|
| Alcohol | Side effects such as dizziness and drowsiness can be greatly increased. Avoid alcohol completely while taking this medication. |
| Other antiepileptic drugs | Medicines such as Carbamazepine, Phenytoin, and Topiramate can affect the action of Perampanel. |
| Medications for depression and anxiety | When taken with medications such as Amitriptyline, Diazepam, and Lorazepam, drowsiness and decreased attention may occur. |
| Birth control pills | Birth control pills containing levonorgestrel may be less effective, so talk to your doctor about using another form of birth control, such as condoms. |
| Other medications | Antifungals (Ketoconazole), some painkillers (Opioids), and traditional medicines such as St. John's Wort can also cause problems. |
Things to be especially careful about when taking medication
- Driving and operating machinery: This medicine may make you feel sleepy, dizzy, and have problems with balance (coordination) . Therefore, avoid driving or operating dangerous machinery until you know exactly how this medicine affects you.
- Serious skin reactions: Although rare, serious skin reactions may occur within weeks or months of starting this medicine. Seek immediate medical attention if you have symptoms such as fever, body aches, red or purple skin rash, blistering, or peeling skin.
- Mental health changes: This is very important. If you experience sudden changes in your behavior, mood (e.g., irritability, restlessness), increased depression, or suicidal thoughts while taking this medication, tell your doctor or a family member right away.
- Medical ID: Carrying a medical ID (bracelet or card) that lists your condition and medications can be very useful in an emergency.
What are the possible side effects?
Like any medicine, Perampanel can cause side effects. Some are serious, while others are common. It's important to be aware of these.
| Serious side effects that should be reported to the doctor immediately | |
|---|---|
| |
| Side effects that are usually not dangerous, but should be reported to the doctor if they persist | |
|
How do you store and dispose of medication?
Keep this medicine at room temperature (20-25 degrees Celsius) in a safe place out of the reach of children and pets . Protect it from theft as it can be abused. This medicine has been prescribed for you only. Do not share it with others.
It is important to properly dispose of expired or no longer needed medications. Check the directions on the medication label or package. If you are unsure, ask your doctor. If it is appropriate to throw the pills in the trash, remove them from the container, mix them with something like used coffee grounds, soil, or cat litter, and place them in a tightly sealed bag and throw them in the trash.
Take-Home Message
- Perampanel is a medication that controls seizures. Always take the dose and time prescribed by your doctor.
- Do not stop taking the medication suddenly for any reason without medical advice.
- Tell your doctor about all other medications you are taking (including birth control pills).
- Be aware of dangerous side effects, such as severe skin reactions or mood changes. If you notice any of these, seek medical advice immediately.
- Avoid drinking alcohol completely while taking this medication. Avoid driving until you know how the medication affects you.
- Keep the medicine in a safe place out of the reach of children and pets.
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