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Prescribed Selexipag injection for lung blood pressure? Here is everything you need to know in plain English.

Dr. Priya Sammani (MBBS)

Medically reviewed by Dr. Priya Sammani (MBBS) — Updated on Oct 21, 2026 · 7 min read

Prescribed Selexipag injection for lung blood pressure? Here is everything you need to know in plain English.
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Has your doctor or a doctor recently prescribed an injection called Selexipag for you or a loved one? Hearing about a new medical treatment can feel overwhelming and confusing. It is completely normal to have many questions swirling around in your head.

Please do not worry or feel stressed about this. We are going to break down everything you need to know about this medicine in a very simple, easy-to-understand way. Let us walk through how it works, what to expect, and how to stay safe.

Key Takeaways at a Glance

  • Selexipag is a specialized medicine given through a vein to treat high blood pressure in your lungs.
  • It helps relax your blood vessels so your heart can pump blood through your body with less effort.
  • Always share your complete medical history and current list of medicines with your doctor before starting.
  • Never share this medicine with anyone else, as it is strictly prescribed for your unique condition.
  • Contact your doctor right away if you notice severe allergic signs like swelling, rash, or trouble breathing.
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What Kind of Medicine Is Selexipag?

Put simply, Selexipag is a specialized medicine used to treat a condition called pulmonary arterial hypertension, or PAH for short. Let us explain what this long medical term actually means for your body.

PAH happens when the blood vessels inside your lungs develop unusually high blood pressure. When these vessels tighten up, your heart has to work much harder to push blood through your lungs and out to the rest of your body.

Over time, this extra strain makes your heart tired. Selexipag helps your body in a few very important ways:

  • It gently relaxes the tight blood vessels located inside your lungs.
  • It lowers the dangerous pressure built up inside those specific vessels.
  • It helps your heart pump blood smoothly without needing to work so hard.

As a result of this treatment, breathing becomes much easier for you. You will also find it simpler to handle your daily activities with more energy and less fatigue.

Things You Must Tell Your Doctor Before Taking This Medicine

Before you start receiving Selexipag, you must sit down and have an honest chat with your medical team. Your safety is the top priority, so you should never hide any health details from your doctor.

Be sure to let your doctor know if any of the following situations apply to you:

  • You currently have any liver disease or liver function problems.
  • You have been diagnosed with pulmonary veno-occlusive disease, known as PVOD.
  • You have ever had a bad allergic reaction to Selexipag, dyes, preservatives, or other medicines.
  • You are currently pregnant, planning to become pregnant, or trying to start a family.
  • You are breastfeeding or planning to breastfeed your baby.

Your doctor will carefully review these facts to decide if this specific medicine is safe and right for your health needs.

How Is This Injection Given and What Happens in an Emergency?

You cannot use this medicine at home by yourself. Selexipag is given directly into a vein as an intravenous injection. Trained medical professionals will give you this treatment safely inside a hospital or specialized clinic.

Important Note: This medicine is prescribed exclusively for your specific health condition. Never share your treatment with anyone else under any circumstances.

What Happens If You Receive Too Much Medicine?

Because doctors manage your dose inside a clinical setting, an accidental overdose is very rare. However, if you ever feel that you received too much medicine, tell your medical team right away.

If you are at home and experience a medical emergency, call 911 in the US or 999 in the UK right away. You can also contact your local poison control center or visit the nearest emergency department right away.

Are There Other Medicines That Do Not Mix Well With Selexipag?

Yes, there are certain medicines that can interact poorly with Selexipag. Because of this, you must share a complete list of everything you take. This includes prescription drugs, over-the-counter pills, vitamins, herbal supplements, and traditional remedies.

Let us look at common medicine interactions in the table below:

Interaction Category Example Medicines
Do Not Take Together Gemfibrozil
Use With Extreme Caution Clopidogrel, Deferasirox, Rifampin, Teriflunomide

Always remember that this list is not complete. If you smoke tobacco or drink alcohol, be sure to mention those habits to your doctor as well.

What Kinds of Side Effects Might You Experience?

Just like most medical treatments, Selexipag can cause unwanted side effects in some people. Keep in mind that not every patient experiences these reactions.

Side Effect Type Description & What to Do
Severe Allergic Reactions Skin rash, itching, hives, or swelling of your face, lips, tongue, or throat. Report right away.
Common Mild Side Effects Diarrhea, headaches, muscle pain, nausea, vomiting, or soreness at the injection site. Tell your doctor if these persist.

If you notice any unusual symptoms that are not listed here, do not hesitate to discuss them with your doctor during your next visit.

When to Seek Emergency Help

Call 911 (US/Canada) or 999 (UK) or go to the nearest emergency room right away if you experience sudden chest pain, severe trouble breathing, fainting, or signs of a severe allergic reaction like facial swelling and hives.

💡 Take-Home Message

  • Selexipag is a specialized intravenous treatment given in a hospital to manage high blood pressure in your lungs.
  • Before starting, tell your doctor about all existing health conditions, especially liver issues and current medicines.
  • Seek medical help right away if you develop serious allergy signs like facial swelling or skin rashes.
  • This medicine is meant solely for you and must never be shared with other people.
  • Always talk openly with your doctor if you have any questions or worries about your treatment plan.
❓ FAQ

Frequently Asked Medical Questions (FAQ)

Evidence-based clinical answers to common patient questions

Can I take Selexipag injection at home by myself?

No, you cannot take this medicine at home. It must be given directly into a vein by trained medical professionals in a hospital or clinic setting to ensure your safety.

What is the main purpose of Selexipag?

Selexipag is used to treat pulmonary arterial hypertension. It relaxes the blood vessels in your lungs so your heart can pump blood more easily and reduce breathlessness.

What should I do if I miss an appointment for my injection?

If you miss a scheduled treatment session, contact your clinic or doctor right away to reschedule. Do not try to double up doses on your own.

Are there foods I should avoid while taking this medicine?

Most patients do not need specific dietary restrictions, but you should always talk to your doctor about your regular diet, alcohol intake, and any herbal supplements.

How do I know if I am having a bad allergic reaction?

Signs of a severe allergic reaction include skin rashes, hives, itching, and swelling of your face, lips, tongue, or throat. Seek emergency medical care right away.

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Verified Scientific & Medical References (PubMed / WHO)

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⚠️ Important: Medical articles and information on Nirogi Lanka are strictly for educational and awareness purposes and do not substitute professional medical advice, diagnosis, or treatment. Always consult a qualified physician for any medical concerns.