Menopause, the time when menstruation stops, can bring various physical discomforts to a woman. The most common of these is sudden sweating and hot flashes. This condition can be so distressing for some that they are unable to perform their daily activities. So, today we are talking about a special medicine that doctors prescribe to control these symptoms. That is a type of hormone pill called Synthetic Conjugated Estrogens.
What exactly is this medicine called estrogen?
Simply put, this is a synthetic medicine that is similar to the hormone estrogen that is naturally produced in the female body. During menopause, the body's estrogen levels decrease. This medicine works by restoring the declining hormone levels to some extent and reducing the discomfort caused by it, especially hot flashes . We also call this Hormone Replacement Therapy (HRT) .
In addition to this main reason, your doctor may also prescribe this medication for some other medical conditions.
Things you need to tell your doctor before taking this medicine
Before you start taking this medicine, it is very important to inform your doctor about your complete health history. This medicine may not be suitable for people with certain medical conditions. Be sure to tell your doctor if you have any of the following conditions:
Cancer and its associated risks
- If you have or have ever had cancer of the breast, cervix, endometrium, ovaries, liver, or uterus.
- If someone in the family, especially a mother or sister, has had breast cancer.
Issues related to the heart, blood vessels, and blood clots
- If you have high blood pressure.
- If you have heart disease or have recently had a heart attack.
- If you have had a previous stroke.
- If you have blood vessel disease, or blood clots in the legs or lungs.
- If the cholesterol level in the blood is high.
Other health conditions
- If you have unusual vaginal bleeding for no known reason.
- If you have diabetes.
- If you have a liver or kidney disease.
- If you have gallbladder disease.
- If you have uterine diseases such as endometriosis or fibroids .
- Migraine, that is, if you have a migraine .
- If the calcium level in the blood is high.
- If you have mental illnesses such as depression.
- If you have dementia or are at risk for it.
- If you are a smoker (this is very important).
- If you are trying to get pregnant, are pregnant, or are a breastfeeding mother.
- If you have allergies to this estrogen pill or any other medicine, food, or dye.
How should I use the medicine?
It is very important to take this medicine exactly as prescribed by the doctor, in the correct dosage.
- Swallow this pill with a glass of water.
- Get into the habit of taking your medication at the same time every day. That way, you won't forget and it'll be easier to keep your body's hormone levels consistent.
- Do not take more than the doctor prescribed, or take it more frequently.
- Always read the patient package insert carefully when you take your medicine.
- If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Never take two doses at the same time.
Warning: This medicine has been prescribed for you only. Do not give this medicine to anyone else who has the same symptoms as you.
Overdosage
If you accidentally take too much of this medicine, immediately call the National Poisons Information Centre at the Colombo National Hospital . Or go to the Emergency Department (ETU) of the nearest hospital.
Be careful of these things when taking medicine.
It is very important to constantly monitor your health while using this medicine.
- Regular medical checkups: Go for regular medical checkups as prescribed by your doctor. Talk to your doctor about whether and how often you should have a mammogram, as well as a breast exam, pelvic exam, and Pap smear.
- Avoid smoking: This is very important. If you smoke while taking this medication, your risk of blood clots and stroke increases significantly. This risk is especially high if you are over 35 years of age .
- Water retention: This medicine can sometimes cause water retention, swelling in the hands, feet, or ankles. It can also increase blood pressure. Tell your doctor if you experience any of these changes.
- Thickening of the uterine lining: When estrogen-only pills are taken for a long time, there is a risk that the lining of the uterus (endometrium) may thicken excessively and eventually turn cancerous (endometrial hyperplasia). To prevent this, unless your uterus has been removed by surgery (hysterectomy), your doctor may prescribe another hormone called progestin along with your estrogen pills. Your doctor will explain this to you in more detail.
- Eye discomfort: The medication may cause dry eyes and blurred vision. If you wear contact lenses, you may experience some discomfort. Lubricating eye drops may be used if necessary. If the problem persists, see your doctor.
- Before surgery: If you are going to have any surgery, talk to your doctor beforehand and ask if you need to temporarily stop taking this medication.
Possible side effects of the medicine
Like any medicine, this one can cause some side effects. The table below clearly shows them.
| Side effect | Description and what to do |
|---|---|
| Serious side effects that require immediate reporting to your doctor or going to the hospital | |
| Allergic reactions | Skin rash, itching, swelling of the face, lips or tongue. |
| Chest pain, difficulty breathing | This could be a sign of a heart attack or a blood clot in the lungs. |
| Symptoms of a stroke | Numbness on one side of the face, arm, or leg, weakness, difficulty speaking, confusion, difficulty walking, dizziness. |
| Symptoms of a blood clot | Pain, swelling, redness, and warmth in the leg. |
| Liver problems | Yellowing of the eyes or skin, dark urine, pale stools, pain in the upper right side of the stomach, nausea. |
| Other serious symptoms | Unusual vaginal bleeding, lumps or changes in the breasts, discharge from the breasts, severe headaches, changes in vision. |
| Side effects that are usually not serious, but should be reported to your doctor if they persist: | |
| Minor inconveniences | Hair loss, increased hunger or thirst, frequent urination, vaginal infections (itching, unusual discharge), feeling unusually tired. |
Other things that may interact with this medicine
You should also tell your doctor about any other medications, herbal products, or supplements you are taking. Some medications can interact with this estrogen medication. In particular, medications such as aromatase inhibitors for cancer should not be taken with this medication. Also, some medications for epilepsy, fungal infections, some antibiotics, and even grapefruit juice can affect the way this medication works.
Take-Home Message
- This medication is a hormonal treatment for the discomforts of menopause. It should only be used under the supervision of a doctor.
- Before starting the medication, tell your doctor about all your medical conditions and all other medications you are taking.
- Avoid smoking completely while taking this medication. It greatly increases the risk of blood clots and stroke.
- Never skip the regular breast and vaginal exams your doctor prescribes.
- If you notice anything like unusual vaginal bleeding, chest pain, leg swelling, or signs of a stroke, seek medical advice immediately.
- This medicine is for you only. Never share it with others.


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