Did the doctor prescribe medicine for your blood pressure? You must have felt a little scared and curious when you saw that pill with two names. What exactly is this? Is it okay to take these together? You must have many questions in your mind. Don't worry, today we are talking about just such a medicine. It is a combination of two drugs called Trandolapril and Verapamil.
What exactly is this medicine?
Simply put, this is a medicine that is given to control your high blood pressure . However, it contains two types of drugs combined.
1. Trandolapril: This belongs to a class of drugs called ACE inhibitors . Think of the blood vessels in your body as pipes that carry water. If these pipes become a little narrowed, more pressure is needed to move the water, right? That's how blood pressure is. What this ACE inhibitor does is relax the blood vessels. Then the blood can move more easily, and the pressure decreases.
2. Verapamil: This belongs to a class of drugs called calcium channel blockers . It works by relaxing the heart and blood vessel walls. This means it helps to lower blood pressure by controlling the heart rate and relaxing the blood vessels.
When these two types come together, they work in different ways and help you control your blood pressure.
Things you should tell your doctor before taking this medicine
The more complete your doctor has of you, the safer you can be treated. Therefore, if you have any of the following conditions, be sure to tell your doctor before starting this medication.
| Status | Description |
|---|---|
| Pregnancy | If you are pregnant, trying to get pregnant, or breastfeeding. (This is very important) |
| Allergies | If you have previously had an allergy to this type of medication, other medications, foods, or insect stings. |
| Heart disease | Other heart conditions, such as irregular or slow heartbeats, and low blood pressure. |
| Kidney or liver disease | If you have any kidney or liver disease. |
| Immune system diseases | Diseases such as lupus, scleroderma, or bone marrow diseases. |
| Pre-existing swelling | If you have swelling of the tongue, face, or lips, difficulty breathing, difficulty swallowing, or hoarseness of voice. |
| Special eating patterns | If you are following a special diet, such as a low-salt diet. |
How should I use this medicine?
- Take this medicine exactly as prescribed by your doctor, at the prescribed time. It is usually best to take it at the same time every day.
- Take this medicine with food .
- Do not stop taking the medication for any reason unless your doctor tells you to.
- Talk to your doctor about using this medicine in children, as special care may be required.
What to do if you take too much medicine?
If you think you have taken more than the prescribed dose, go to the nearest hospital Emergency Department (ETU) immediately . Or call the National Poisons Information Centre at the Colombo National Hospital for advice.
Important: This medicine has been prescribed for you only. Never share this medicine with anyone else, even if they have the same symptoms as you. It can be dangerous.
What if I miss a dose of medication?
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Never take two doses at the same time.
Other medications that may interact with this medicine
It is very important to tell your doctor about all the medications you are taking, including vitamins, herbs, and supplements. Some medications can interact with this medicine and cause dangerous conditions.
| Medications that should never be taken with these drugs | |
|---|---|
| - cisapride | - disopyramide |
| - dofetilide | - flibanserin |
| - lomitapide | - sacubitril; valsartan |
| - tranylcypromine | |
| Other medications that may interact (medical advice required) | |
| - Some medications for diabetes and cholesterol | - Painkillers (NSAIDs - e.g. ibuprofen) |
| - Diuretics | - Potassium supplements or tablets |
| - Some antibiotics used to treat infections (e.g. clarithromycin) | - Lithium, cimetidine, a St. John's Wort |
This list is not complete, so tell your doctor about everything you take.
Things to be careful about when taking medicine
- Check your blood pressure: See your doctor regularly and share your progress. If you measure your blood pressure at home, talk to your doctor about the readings.
- Dizziness and drowsiness: This medicine may make you feel a little dizzy and drowsy. Therefore, stay away from dangerous activities such as driving or operating machinery until you know how this medicine affects you. Be careful when getting up from a sitting or standing position suddenly.
- Pregnancy: > Special notice for women: If you are planning to become pregnant or suspect you are pregnant, tell your doctor immediately. This medicine can cause serious harm to an unborn baby.
- Vomiting and diarrhea: Tell your doctor if you have excessive vomiting, diarrhea, or excessive sweating. It can be dangerous to take this medicine if you lose too much water from your body.
- Cough, cold: Do not take over-the-counter medications for cough, cold, or pain while taking this medicine. Some medications can increase your blood pressure. Ask your doctor before taking anything.
- Teeth and Gums: Some people may experience gum swelling due to this medicine. So brush your teeth thoroughly every day. If you feel your gums are swollen or red, see a dentist.
Possible side effects of the medicine
Like any medication, this one can have side effects. Not everyone gets them. But it's important to be aware of them.
| Serious side effects that should be reported to the doctor immediately | |
|---|---|
| Allergic reactions | Skin rash, itching, swelling of the hands, feet, face, lips, tongue or throat. |
| Difficulty breathing | Difficulty breathing or swallowing, throat tightness. |
| Changes in heart rate | Irregular, rapid heartbeat, chest pain. |
| Persistent dry cough | A dry, annoying cough that has been going on for quite some time. |
| Other features | Decreased urine output, stomach pain, swelling of the legs and ankles, skin blisters or sores. |
| Usually not serious (but tell your doctor if it persists) | |
| Headache | Dizziness or drowsiness |
| Facial flushing | Decreased sexual desire or activity |
If you experience any other unusual symptoms not mentioned in this list, talk to your doctor about them as well.
How should I store the medicine?
- Keep out of reach of children and pets.
- Store at room temperature (between 20-25 degrees Celsius).
- Throw away expired medications.
Take-Home Message
- Trandolapril and Verapamil are a combination of two medications used to treat high blood pressure.
- Before starting this medication, tell your doctor about all your medical conditions and all medications you are taking.
- Avoid taking this medicine if you are pregnant, trying to become pregnant, or breastfeeding. Tell your doctor immediately.
- Avoid risky activities as dizziness and drowsiness may occur while taking the medication.
- If you experience severe allergy symptoms such as swelling of the throat, face, or difficulty breathing, go to a hospital immediately.
- Do not stop taking the medication or change the dosage without your doctor's advice.
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