Ua lohe anei ʻoe i kēia ʻano puʻupuʻu e ulu ana i loko o nā ovaries? (Granulosa Cell Tumor) E kamaʻilio kākou e pili ana!

ʻAʻole paha ʻoe i lohe i kēia inoa ma mua - ʻo Granulosa Cell Tumor kahi ʻano puʻupuʻu kakaikahi e hiki ke ulu i loko o nā ovaries o nā wahine. Akā, mai makaʻu i kou lohe ʻana i ka inoa, ʻae? E kamaʻilio maʻalahi mākou e pili ana i kēia, i hiki iā ʻoe ke hoʻomaopopo. No ka mea, he mea waiwai nui ka ʻike e pili ana i kekahi mea.

He aha ka Granulosa Cell Tumor? E hoʻomaopopo maʻalahi kākou!

I ka ʻōlelo maʻalahi, ʻo kēia `(Granulosa Cell Tumor)` he puʻupuʻu kūikawā (puʻupuʻu) e ulu ana i loko o nā ovaries o kā mākou wahine . ʻO nā ovaries, e like me kou ʻike, he ʻano koʻikoʻi loa ia i loko o ko mākou kino e hana ana i nā hua, a me nā hormones wahine e like me `(Estrogen)` a me `(Progesterone). ʻO kēia ʻano puʻupuʻu, e pololei, no ka māhele o `(sex cord-stromal tumor)`. Ke ulu kēia puʻupuʻu, piʻi pinepine ka pae o `(Estrogen)` i loko o ke kino . ʻOiai hiki ke ulu kēia i kēlā me kēia makahiki, ʻike pinepine ʻia ma kahi o 50 mau makahiki.

Ma hea e hoʻokumu ʻia ai kēia mau puʻupuʻu?

Hoʻomohala ʻia nā ʻōpū cell Granulosa (GCT) i loko o nā ovaries . ʻO nā ovaries kekahi ʻāpana o ka ʻōnaehana hānau wahine. Ma waho aʻe o ka hana ʻana i nā hua (ova), hana pū nā ovaries i nā hormones hānau estrogen a me progesterone.

Pehea ka maʻamau o kēia mau mea?

He mea kākaʻikahi loa kēia, i kapa ʻia ʻo "Granulosa Cell Tumors". Hana lākou ma kahi o 5% o nā ʻōpū ovarian mua. No laila, e like me kāu e ʻike ai, ʻaʻole kēia he mea maʻamau.

He maʻi kanesa anei kēia? A i ʻole he mau puʻupuʻu wale nō?

ʻO ka nīnau nui loa no nā poʻe he nui, inā he maʻi kanesa weliweli kēia a he puʻupuʻu wale nō paha. ʻO ka ʻoiaʻiʻo, ʻo kēia mau puʻupuʻu cell granulosa he mau maʻi ʻino paha, a he kanesa paha .

Akā, aia ka nūhou maikaʻi ma ʻaneʻi. ʻO kēia mau ʻano puʻupuʻu (GCT) he lohi pinepine ka ulu ʻana . ʻO ia hoʻi, ʻaʻole lākou e laha koke. No laila, hiki i nā kauka ke ʻike mua iā lākou, a laila ʻoi aku ka kiʻekiʻe o ka loaʻa ʻana o nā hopena maikaʻi mai ka mālama ʻana.

Aia kekahi ʻokoʻa ma waena o ka Granulosa Cell Tumor i nā pākeke a me nā ʻōpio?

ʻAe, aia kahi ʻokoʻa iki ma aneʻi. ʻIke pinepine ʻia kēia mau puʻupuʻu i nā wahine ʻelemakule. ʻO ka ʻoiaʻiʻo, 95% o nā GCT āpau i ʻike ʻia aia i loko o nā wahine ʻelemakule i ulu maikaʻi .

Eia nō naʻe, he mea kākaʻikahi, inā ulu kēia puʻupuʻu i loko o kekahi kanaka ma lalo o 30 makahiki, ua kapa ʻia ʻo ia he juvenile granulosa cell tumor (JGCT) . ʻO kēia ʻano puʻupuʻu e ulu ana i loko o ka poʻe ʻōpio, inā ua pālahalaha ma waho o ka ovary, i kekahi manawa ʻoi aku ka nui o ka hiki ke hoʻi hou i loko o kekahi mau makahiki ma mua o ke ʻano e ulu ana i loko o ka poʻe ʻelemakule., a hiki nō hoʻi ke hana me ka huhū iki.

No ke aha e hana ʻia ai kēia mau puʻupuʻu cell granulosa? He aha ke kumu?

ʻO kēia ka pilikia i loaʻa i nā kānaka he nui. ʻO ka ʻoiaʻiʻo, ʻaʻole maopopo loa i nā loea lapaʻau ke kumu maoli o kēia . Eia naʻe, ʻo ka mea a lākou i ʻike ai, he nui ka poʻe me kēia mau puʻupuʻu i loaʻa kahi loli, a i ʻole mutation, i loko o kahi gene i kapa ʻia ʻo ``(FOXL2)``. ʻO ka maʻamau, kōkua kēia gene ``(FOXL2)`` i nā cell granulosa e ulu pono a olakino. No laila, inā he loli i loko o kēia gene, ua manaʻo ʻia ʻo ia kekahi o nā kumu e ulu ai kēia mau puʻupuʻu.

He aha nā hōʻailona o kahi Granulosa Cell Tumor?

ʻO ka hōʻailona nui i ʻike ʻia ma kēia, ʻo ia ka piʻi ʻana o ka nui o ka hormone estrogen i loko o ke kino .

• No ke kaikamahine ʻōpiopio , hiki i kēia estrogen keu ke kumu iā ia e hele i ka wā ʻōpio i ka wā ʻōpiopio . ʻO ke ʻano kēia e ulu paha kona mau umauma ma mua o ka makahiki maʻamau a ulu ka lauoho ma nā wahi pilikino.
• ʻO ka hapa nui o nā wahine makua e ʻike i nā hōʻailona e like me:
• He hōʻailona koʻikoʻi loa ke kahe koko ʻana o ka ʻōpū maʻamau (AUB) a i ʻole ke kahe koko ma hope o ka menopause .
• Ka piʻi ʻana o ka ʻōpū (manaʻo piha) .
• Ka hoʻopau ʻana o ka menstruation i ke ʻano kūpono ʻole a i ʻole ka pau ʻana o ka menstruation no kekahi manawa.
• ʻEha umauma, palupalu (nā umauma palupalu a ʻeha paha) .

I kekahi manawa, hiki i kēia puʻupuʻu ke hōʻeha i ka ʻōpū inā pohā wale nō . Akā, ʻaʻole ia e hana i nā kānaka a pau.

He aha nā pilikia e hiki ke kū mai ma muli o kēia puʻupuʻu?

Inā ʻaʻole mālama pono ʻia kēia puʻupuʻu cell granulosa, hiki iā ia ke hoʻonui i ka pilikia o nā pilikia olakino ʻē aʻe. No laila he mea nui e ʻike koke a mālama iā ia. ʻO kekahi o nā pilikia nui e hiki ke hana ʻia:

• ʻO ka hyperplasia Endometrial : Hiki i kēia ke lilo i mea mua i ka maʻi ʻaʻai uterine.
• Ka maʻi ʻaʻai o ka ʻōpū .
• Ka maʻi ʻaʻai umauma .
• Ka paʻakikī i ka hānau keiki ʻana (Infertility) .

Pehea e ʻike ai nā kauka i kēia `(Granulosa Cell Tumor)`?

ʻO ka maʻamau, hoʻohana nā kauka i nā ʻano hana kiʻi like ʻole e ʻike ai i nā ʻōpū cell granulosa. Pono paha ʻoe e loaʻa nā hoʻokolohua e like me kēia:

• ʻO kahi scan CT .
• ʻO kahi scan MRI .
• ʻO ka ultrasound transvaginal : ʻAe kēia i nā ovaries e ʻike maopopo ʻia.

Eia kekahi, hiki i kāu kauka ke kauoha i nā hoʻāʻo koko . ʻO ke kikoʻī, e ʻimi lākou i kahi mea i kapa ʻia ʻo nā māka tumor . ʻO Inhibin kahi māka kūikawā i hana ʻia e kēia mau tumors cell granulosa a hiki ke loaʻa i loko o ke koko. Hiki iā lākou ke kauoha i kekahi mau hoʻāʻo koko e kāpae i nā kūlana ʻē aʻe.

Pehea e mālama ʻia ai nā ʻōpū cell granulosa?

ʻO ke ʻoki kino ka lāʻau mua a nui hoʻi no kēia . Hoʻāʻo ke kauka ʻoki kino e wehe i ka nui o ka puʻupuʻu e like me ka hiki, me ka mālama pono ʻole e hōʻino i nā ʻiʻo olakino.

• Inā ʻaʻole ʻoe makemake hou e loaʻa nā keiki, a inā ua hala ʻoe i ka makahiki hānau keiki, hiki i kāu kauka ke ʻōlelo aku e wehe i kāu mau ovaries (oophorectomy) a me kou uterus paha (hysterectomy) . I kekahi mau hihia, pono ka wehe ʻana i nā ovaries e wehe i ka GCT holoʻokoʻa.

ʻO ka mea aʻe, hoʻoholo nā kauka i ka mamao o ka laha ʻana o ka puʻupuʻu, a i ʻole ke ʻano o ka "stage" o ka puʻupuʻu . Penei lākou e hoʻoholo ai inā ua laha ka maʻi ʻaʻai a ʻaʻole paha.

• ʻO ke ʻano o ka GCT ma ka pae 1 ʻaʻole i pālahalaha ka puʻupuʻu ma waho o nā ovaries.
• ʻO ke kahua 2 a 4 GCTs ke ʻano ua pālahalaha ka puʻupuʻu (metastasized) i nā ʻāpana ʻē aʻe o ke kino.

E noʻonoʻo, ʻo ka mea maikaʻi loa, ʻo 9 o kēlā me kēia 10 GCT i loaʻa i loko o ka ovary . No kēia ʻano puʻupuʻu, ʻōlelo pinepine ʻia ke ʻoki ʻana, a ʻo ia wale nō paha ka lāʻau lapaʻau.

Eia nō naʻe, ma muli o ka nui o ka puʻupuʻu a me kāu mau kumu pilikia no ka hoʻi hou ʻana, hiki ke hāʻawi ʻia nā lāʻau lapaʻau hou aʻe e pale aku i ka hoʻi hou ʻana o ka puʻupuʻu. Hiki i kāu kauka ke ʻōlelo i kēia mau mea:

• Kemoterapia
• Hoʻōla lāʻau hormone
• Hoʻōla radiation

Aia kekahi ala e pale aku ai i kēia puʻupuʻu cell granulosa mai ka hoʻokumu ʻana?

ʻAʻohe ala maopopo e pale aku ai i kēia mai ka hana ʻana . Eia nō naʻe, ʻo ke ola ʻana i kahi nohona olakino holoʻokoʻa a me ka hōʻemi ʻana i kou pilikia o nā maʻi maʻi hiki ke kōkua i kekahi ʻano. ʻO ia hoʻi:

• Ka mālama ʻana i kahi kaumaha olakino e kūpono i ke ʻano o kou kino, ke kāne, a me ka makahiki.
• E hōʻole loa i ka puhipaka .
• ʻAi i ka meaʻai momona (nā mea kanu, nā huaʻai, a me nā greens).
• He mea nui ka hoʻoikaika kino mau no ke olakino o ka puʻuwai a me ka ikaika o ka iwi.
• Ka palena ʻana i ka inu ʻana i ka waiʻona a me ka caffeine .
• Ka mālama ʻana i ke kaumaha ma o nā hana e like me ka noʻonoʻo ʻana a me ka yoga.
• E hiamoe maikaʻi ma ka liʻiliʻi he ʻehiku a ʻewalu hola i ka pō.

Pehea e hōʻemi ai i ka pilikia o nā pilikia mai kahi `(Granulosa Cell Tumor)`?

ʻO ka mea nui loa, ʻo ia ke ʻike koke i ke kauka inā loaʻa iā ʻoe kekahi mau hōʻailona e pili ana i ka `(GCT)` . ʻOi loa aku, inā he kahe koko kūpono ʻole kou, ʻeha umauma, palupalu, a kahe koko paha ma hope o ka menopause, pono ʻoe e ʻimi i ke aʻo lapaʻau . ʻO ka `(GCT)` ka mea maʻamau e holomua loa ke mālama ʻia i ka wā mua.

Hiki ke ho'ōla ʻia nā ʻōpū cell granulosa?

ʻAe, hiki ke ho'ōla ʻia . ʻOi aku hoʻi me ke ʻoki ʻana, ʻoi aku ka kiʻekiʻe o ka manawa e ho'ōla ʻia ai inā e wehe koke ʻia kēia mau puʻupuʻu .

Eia nō naʻe, inā loaʻa i ke kauka, ʻaʻole paha e ho'ōla i ka GCT inā ua pālahalaha mua ia i nā ʻāpana ʻē aʻe o ke kino. ʻO ia ke kumu e ʻōlelo mau ai mākou inā loaʻa iā ʻoe nā hōʻailona o ka GCT, e ʻike koke i ke kauka .

He aha ka mea e manaʻo ai ma hope o ka mālama ʻana o GCT?

Ma hope o ka wehe ʻia ʻana o ka puʻupuʻu, pono ʻoe e ʻike pinepine i kāu kauka no kekahi mau makahiki no ka nānā ʻana . ʻO kēia no ka mea hiki i nā puʻupuʻu ke hoʻi hou mai i kekahi manawa i nā makahiki ma hope. E nānā pinepine kāu kauka e ʻike inā ua hoʻi mai ka puʻupuʻu. Hiki i kēia ke komo pū me:

• Nā hoʻokolokolo Pelvic .
• Nā hoʻāʻo koko e nānā i nā hōʻailona o ka hoʻi hou ʻana o ka maʻi kanesa.
• Nā hoʻāʻo scan .

He aha ka nānā ʻana no nā ʻōpū cell granulosa?

ʻO ka nānā ʻana no kahi GCT e pili ana i ka holomua o ka puʻupuʻu (kahua) i ka wā i ʻike ʻia ai ʻoe . Inā ʻike kāu kauka i kahi GCT ma mua o ka laha ʻana (metastasizes) i nā ʻāpana ʻē aʻe o ke kino, maikaʻi ka nānā ʻana .

He aha hou aʻe kaʻu e nīnau aku ai i kaʻu kauka?

Inā makemake ʻoe e ʻike hou aku e pili ana i kēia, hiki iā ʻoe ke nīnau i kāu kauka i nā nīnau e like me kēia:

• He aha ke kumu kūpono loa o koʻu mau hōʻailona?
• He aha nā hoʻokolohua e pono iaʻu e hana e hōʻoia inā loaʻa iaʻu kahi Granulosa Cell Tumor?
• He aha nā koho lapaʻau e loaʻa iaʻu?
• He aha ka manawa kūpono e hoʻi hou mai ai kēia `(GCT)` ma hope o ka mālama ʻana?
• He aha koʻu manaʻo ma hope o ka wehe ʻana i kahi puʻupuʻu cell granulosa?

ʻO nā mea nui e pono ai ʻoe e hoʻomanaʻo mai kēia ʻatikala (Leka Lawe-Home)

ʻAe, no laila, mai nā mea a mākou i kamaʻilio ai, eia nā mea nui loa e pono ai ʻoe e hoʻomanaʻo:

• He ʻōkō laha ʻole ka maʻi granulosa cell, he ʻōkō maikaʻi ʻole ia e ulu ana i loko o nā ovaries .
• I ka manawa pinepine ma muli o kēia mau meaKe piʻi nei ka nui o ka hormone estrogen i loko o ke kino.
• No laila, hiki ke ʻike ʻia nā hōʻailona e like me ke kahe koko ʻana o ka ʻōpū ma ke ʻano ʻē, nā pōʻaiapuni menstrual kūpono ʻole, a me ka ʻōpū nui .
• ʻO ke ʻano nui o ka lāʻau lapaʻau, ʻo ia ka wehe ʻana i ka puʻupuʻu ma ke ʻoki ʻana .
• ʻO ka mea nui loa, inā e ʻike mua ʻia kēia mau mea, ʻoi aku ka kiʻekiʻe o ka manawa e ho'ōla hou ai .
• No laila, inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona, ​​​​mai hopohopo a hoʻopaneʻe paha, akā e ʻike koke i ke kauka no ka ʻōlelo aʻo .

Manaʻolana wau he mea pono kēia ʻike nou. E ola kino!

ʻO ka puʻupuʻu cell Granulosa, ka maʻi ʻaʻai ovarian, estrogen, olakino wahine, ke kahe koko ʻē, nā hōʻailona o ka maʻi ʻaʻai, ke ʻoki kino