Ua nāwaliwali anei nā pale o kou kino? E aʻo kākou e pili ana i ka agranulocytosis.

Loaʻa pinepine iā ʻoe ke anu a me ka maʻi palū a maʻi loa ʻoe? I kekahi manawa, hiki i kahi maʻi liʻiliʻi ke lilo i mea koʻikoʻi a lōʻihi ka manawa e hoʻōla ai? ʻO ke kumu nui o kēia paha he nāwaliwali o ka ʻōnaehana pale o kou kino, ʻo ia hoʻi, ka pūʻali koa e pale mai iā mākou mai nā maʻi. I kēia lā, ke kamaʻilio nei mākou e pili ana i kahi kūlana i hiki ke kānalua ʻia i ia mau manawa, kahi mea weliweli iki paha, akā hiki ke mālama ʻia.

I ka ʻōlelo maʻalahi, he aha ka Agranulocytosis?

ʻO ka Agranulocytosis (puana ʻia: "a-gra-nu-lo-cy-to-sis") he kūlana hoʻoweliweli i ke ola kahi e emi nui ai ka helu o nā neutrophils, kahi ʻano keʻokeʻo koko, i loko o ko kākou koko.

E noʻonoʻo ʻoe ua like ko kākou kino me kahi ʻāina. A laila ʻo nā hunaola koko keʻokeʻo ka pūʻali koa e pale ana i kēlā ʻāina. Aia nā pūʻali koa like ʻole i loko o kēia pūʻali koa. I waena o lākou , ʻo nā neutrophils kahi hui commando kūikawā e hele e hoʻouka i nā germs i ka wā e ʻike ai lākou iā lākou . No laila, i ka wā e emi nui ai ka helu o kēia mau commandos, hiki i kahi germ liʻiliʻi mai waho ke hoʻouka maʻalahi i ko kākou kino a hoʻomaʻi iā kākou.

Hiki i kēia kūlana ke hoʻolilo iā ʻoe i mea maʻalahi i nā maʻi koʻikoʻi, ʻoiai mai nā germs i hōʻeha ʻole mai iā mākou.

No laila he aha ka ʻokoʻa ma waena o Neutropenia a me Agranulocytosis?

Ua lohe paha ʻoe i ka huaʻōlelo neutropenia. ʻOiai ua like ke kani ʻana o kēia mau mea ʻelua, aia kahi ʻokoʻa iki.

• ʻO Neutropenia: Kekahi ʻano i emi ai ka nui o nā neutrophils ma mua o ka maʻamau.
• ʻO Agranulocytosis: ʻO kēia ke ʻano koʻikoʻi a weliweli loa o ka neutropenia.

I ka ʻōlelo maʻalahi, ke hāʻule haʻahaʻa loa nā pae neutrophil, kapa mākou ia he Agranulocytosis.

He aha nā kumu o kēia kūlana?

Hiki ke loaʻa ka Agranulocytosis i ʻelua mau ala nui.

1. ʻO ka Agranulocytosis hoʻoilina: Hoʻokumu ʻia kēia e kahi kīnā i loko o nā genes e hana ana i nā neutrophils. He mea kākaʻikahi loa kēia a ʻoi aku ka maʻamau i nā pēpē ʻōpio a me nā keiki.

2. ʻO ka Agranulocytosis i loaʻa: ʻO kēia ke ʻano maʻamau. Hiki ke loaʻa kekahi mau kumu no kēia. Akā ma kahi o 70% o nā hihia, he hopena ʻaoʻao ia o kekahi mau lāʻau lapaʻau a mākou e lawe ai. ʻOi aku ka maʻamau o kēia ʻano i waena o nā pākeke.

ʻO nā kumu nui o ka agranulocytosis ma hope

• Kekahi mau lāʻau lapaʻau: Hiki ke hana ʻia kēia ʻano e nā lāʻau lapaʻau e like me kekahi mau antibiotics, nā lāʻau lapaʻau no nā maʻi noʻonoʻo (e like me clozapine), a me nā lāʻau lapaʻau no nā maʻi thyroid (e like me methimazole).
• Chemotherapy: Ke hoʻopau ʻia nā hunaola kanesa, hiki ke hōʻino ʻia nā neutrophils, ʻo ia hoʻi nā hunaola olakino e māhele wikiwiki ana.
• Nā maʻi Autoimmune: ʻO kēia ka wā e hana hewa ai ka ʻōnaehana pale ponoʻī o ko mākou kino a hoʻouka i kāna mau hunaola olakino ponoʻī. ʻO nā hiʻohiʻona e like me nā maʻi e like me Lupus a me Rheumatoid Arthritis.
• Nā Maʻi ʻIwi: ʻO ka iwi ka hale hana e hana i kā mākou mau hunaola koko āpau. No laila, ʻo nā maʻi e hoʻopilikia nei i kēia hale hana, e like me nā maʻi kanesa e like me ka leukemia a i ʻole ka anemia aplastic, hiki ke hoʻopilikia i ka hana ʻana o nā neutrophil.
• Kekahi mau maʻi: Hiki ke hana ʻia kēia ʻano e nā maʻi koʻikoʻi e like me ka malaria a me ka maʻi puʻupuʻu.
• Nā hemahema meaʻai: Aia pū kēia pilikia me nā hemahema lōʻihi o nā meaʻai e like me ka huaora B12 a me ka folate.
• Nā kemika ʻawahia: Ka ʻai ʻana i nā kemika ʻawahia e like me ke kēpau a i ʻole ka mercury.

He aha nā hōʻailona o ka agranulocytosis?

Ma muli o ka helu haʻahaʻa o nā neutrophils, ʻo nā hōʻailona mua o kēia maʻi, ʻo ia nā hōʻailona o kahi maʻi . Hiki ke ʻike koke ʻia kēia mau mea a ulu mālie paha.

ʻO nā hiʻohiʻona nui i ʻike ʻia penei:

• Ke anu loa nei, ka haʻalulu, a me ke kuni .
• Hoʻonui ʻia ka helu o ka puʻuwai a me ka hanu ʻana.
• Ka manaʻo o ka luhi a me ka nāwaliwali o ke kino i loaʻa ʻole ma mua .
• ʻĀʻī ʻeha, pehu a kahe ke koko o nā ʻāʻī.
• Ke paʻakikī i ka ale ʻana ma muli o nā ʻeha o ka waha a me ka puʻu .
• Ka hāʻule koke ʻana o ke koko (hypotension) e alakaʻi ai i ka manaʻo o ka maʻi ʻūlū a me ka poniuniu.

Pehea e ʻike ai ke kauka i kēia maʻi?

Inā loaʻa iā ʻoe kekahi o nā hōʻailona i helu ʻia ma luna, ʻoiai inā loaʻa iā ʻoe nā maʻi pinepine, e nānā ke kauka iā ʻoe. ʻO ka hoʻāʻo koʻikoʻi e ʻike ai inā loaʻa iā ʻoe kēia ʻano maʻi, ʻo ia ka helu koko piha (CBC) . I kekahi manawa kapa mākou i kēia he helu koko piha (FBC).

Ana kēia hoʻāʻo i ka helu pololei o nā neutrophils i loko o kou koko. Inā emi ka helu neutrophil ma mua o 100 no ka microliter, ua ʻike ʻia he Agranulocytosis.

Eia kekahi, hiki i ke kauka ke kauoha i nā hoʻokolohua hou aʻe e ʻike ai i ke kumu.

• Biopsy ʻAoʻao Iwi: Hana ʻia kēia hoʻāʻo e ʻike inā he pilikia i loko o ka ʻaoʻao iwi, ka hale hana e hana ana i nā hunaola koko.
• Hoʻāʻo Genetic: Inā he kānalua he maʻi hānau kēia, hiki ke kuhikuhi ʻia ʻoe no kēia hoʻāʻo.

He aha nā lāʻau lapaʻau no ka agranulocytosis?

ʻOiai he kūlana weliweli kēia, ʻo ka nūhou maikaʻi, aia nā lāʻau lapaʻau kūpono no ia. Aia ka lāʻau lapaʻau i ke kumu o ke kūlana.

• Ke Hoʻōki ʻana i ka Lāʻau Lapaʻau Kumu: Inā ʻo ke kumu o kēia kūlana he lāʻau lapaʻau āu e lawe nei, ʻo ka mea mua a koʻikoʻi loa e hana ai, ʻo ia ke hoʻōki i ka lawe ʻana i kēlā lāʻau lapaʻau. Eia naʻe, mai hoʻōki i ka lawe ʻana i kāu lāʻau lapaʻau iā ʻoe iho. E kamaʻilio me kāu kauka a hahai i kāna mau ʻōlelo aʻoaʻo e hana pēlā me ka palekana.

• Nā lāʻau lapaʻau antibiotics: Inā loaʻa iā ʻoe kahi maʻi i loko o kou kino, e kuhikuhi kāu kauka i nā lāʻau lapaʻau ikaika e hakakā ai.

• Nā inikini G-CSF: Ua kapa ʻia kēia mau mea ʻo Granulocyte Colony-Stimulating Factor (G-CSF). Hoʻoulu kēia mau inikini i ka iwi iwi a kōkua iā ia e hana i nā hunaola neutrophil me ka wikiwiki.

• Nā Immunosuppressants: Inā he maʻi autoimmune ke kumu, hiki ke hāʻawi ʻia nā lāʻau lapaʻau e like me ka prednisone e hōʻoluʻolu i ka ʻōnaehana pale overactive.

• Hoʻoili iwi iwi: Inā ʻaʻole holomua nā lāʻau ʻē aʻe, hiki ke hana ʻia kahi hoʻoili iwi iwi mai kahi kanaka olakino ma ke ʻano he koho hope loa.

Pehea e hiki ai iaʻu ke pale iaʻu iho mai nā maʻi i ka wā o ka mālama ʻana?

He mea nui loa ia e pale aku i nā maʻi i ka wā e mālama ai i kekahi me kēia maʻi.

• E holoi mau i kou mau lima me ke kopa.
• E ho'ēmi i ka hele ʻana i nā wahi i piha i nā kānaka i ka hiki.
• E ʻaʻahu i ka pale maka i ka wā e hele ai i waho.
• E ʻai wale i ka meaʻai i moʻa maikaʻi ʻia a maʻemaʻe hoʻi.

Hiki ke ho'ōla piha ʻia mai kēia maʻi?

ʻAe, i ka hapa nui o ka manawa hiki. Aia ka manawa ho'ōla ma muli o ke kumu.

Inā he lāʻau lapaʻau ke kumu, hoʻi pinepine ka helu neutrophil i ka maʻamau i loko o 1 a 3 mau pule ma hope o ka hoʻōki ʻana i ka lāʻau.

Inā ʻike ʻia a mālama ʻia i ka wā mua, hiki ke kāohi loa ʻia kēia ʻano. Eia nō naʻe, inā ʻaʻole mālama ʻia, hiki iā ia ke alakaʻi i nā maʻi koʻikoʻi a me nā kūlana hoʻoweliweli ola e like me ka sepsis . ʻO ka poʻe ma luna o 65 mau makahiki a me ka poʻe me nā maʻi puʻuwai, puʻupaʻa, a i ʻole nā ​​​​maʻi māmā ʻē aʻe e ʻoi aku ka nui o ka pilikia o nā pilikia.