Ke hoʻomaka kekahi ʻelemakule i loko o ko mākou hale, ʻo ia hoʻi ko mākou makuahine, makuakāne, kupuna wahine a kupuna kāne paha, e hoʻopoina iki i nā mea, a ke nīnau pinepine lākou i ka mea like, e hopohopo iki ana ko mākou naʻau, ʻeā? ʻO ka nīnau "ʻO kēia anei ka hoʻomaka ʻana o ka maʻi Alzheimer?" e hopohopo ai mākou. ʻOiaʻiʻo, ke lohe mākou i ka maʻi Alzheimer, ʻo ka mea e hiki mai ana i ko mākou manaʻo he kūlana kaumaha kahi e nalowale mālie ai ko mākou hoʻomanaʻo, ʻaʻole hiki ke hana i nā hana maʻamau, a poina hope iā mākou. He ʻoiaʻiʻo kēlā. Akā, ua ʻike anei ʻoe he nui nā ʻano nui o kēia maʻi, ma muli o ke ʻano o kona ulu ʻana, ʻo ia hoʻi, ka makahiki e hoʻomaka ai ka maʻi a me nā kumu? E kamaʻilio wale kākou e pili ana i kēia i kēia lā.
ʻOiai ke ʻokoʻa o nā ʻano o ka maʻi, ua like nō nā hōʻailona maʻamau.
ʻO ka mea mua, e hoʻomaopopo kākou i kēia. Me ka nānā ʻole i ke ʻano o ka maʻi Alzheimer, ua like loa nā hōʻailona i ʻike ʻia e ka hapa nui o nā maʻi i ka hala ʻana o ka manawa.
- Poho ka hoʻomanaʻo: Ka poina ʻana i nā mea, ʻoiai nā mea i hala koke aku nei.
- Huikau: Huikau e pili ana i nā mea e like me ka manawa, kahi, a me nā lā.
- Paʻakikī e hana i nā hana maʻamau: Paʻakikī e hana i nā hana maʻalahi e like me ka hana ʻana i ke kī a i ʻole ke komo ʻana i nā lole na ʻoe iho.
- Paʻakikī i ka hoʻoholo ʻana: Manaʻo ua nalowale, ʻaʻole hiki ke hana i kahi hoʻoholo maʻalahi.
ʻO ke kumu nui o kēia mau mea a pau, ʻo ia ka hōʻiliʻili ʻana o kahi ʻano protein i kapa ʻia ʻo 'amyloid beta peptides' i loko o nā ʻaʻalolo o ko kākou lolo. I ka ʻōlelo maʻalahi, ua like kēia me kahi ʻano "ʻōpala" e hōʻiliʻili ana i loko o ka lolo. ʻO ka maʻamau, hoʻopau ko kākou lolo i kēia ʻano mea pono ʻole. Akā i ka maʻi Alzheimer, ʻaʻole hana pono kēia kaʻina hana. A laila hōʻiliʻili kēia mau protein a hana i nā plaques a me nā hihia i loko o ka lolo. Ma muli o kēia, ua pau ke kahe o ka ʻike ma waena o nā ʻaʻalolo o ka lolo, a make mālie nā ʻaʻalolo. Me ka nānā ʻole i ke ʻano o ka maʻi, he mea maʻamau kēia kaʻina hana.
ʻO nā ʻano nui ʻelua o ka maʻi Alzheimer
Ma muli o ka makahiki o ka hoʻomaka ʻana, hoʻokaʻawale mākou iā ia i ʻelua ʻano nui. E nānā i ka papa ma lalo nei e hoʻomaopopo i nā ʻokoʻa ma waena o kēia mau ʻano ʻelua.
| Hiʻona | ʻO ka maʻi Alzheimer i ka wā mua | ʻO ka maʻi Alzheimer i ka wā lohi |
|---|---|---|
| Ka makahiki o ka hoʻomaka ʻana o ka maʻi | Ma lalo o 65 mau makahiki. ʻO ka maʻamau i ko lākou mau makahiki 40-50. | 65 mau makahiki a ʻoi paha. |
| Ka maʻamau | He mea kākaʻikahi loa, ʻike ʻia ma lalo o 5% o nā maʻi āpau. | ʻO kēia ke ʻano maʻamau. |
| Ka hiki ke hoʻoili i nā hanauna | He pinepine kahi loulou hoʻoilina ikaika. | Hiki iā ia ke ulu inā loaʻa i kekahi o ka ʻohana a ʻaʻole paha. ʻAʻole i ʻike ʻia ke ʻano kikoʻī. |
| Nā loli o ka lolo | Hiki ke ʻike ʻia nā palaki a me nā hiʻohiʻona hou aʻe i loko o ka lolo. Nui ka emi ʻana o ka lolo. | Inā paha e loli ka lolo, he mea liʻiliʻi paha ia. |
| Nā hiʻohiʻona ʻē aʻe | Hiki ke ʻike ʻia ka ʻoniʻoni/ʻūlū koke ʻana o nā ʻiʻo (myoclonus) . | ʻO ka nalowale o ka hoʻomanaʻo ke kumu nui o ka hōʻailona. |
ʻO ka maʻi Alzheimer i ka wā mua
He mea kupanaha paha kēia. Akā ʻae, hiki i kekahi poʻe ke loaʻa i ka maʻi Alzheimer i ka wā ʻōpiopio o 40 a 50 paha mau makahiki. He maʻi laha ʻole kēia. ʻO ke kumu nui o ia mea he mau kīnā genetic . Ma ke ʻano kikoʻī, ua ʻike ʻia ua loaʻa kēia maʻi i nā hemahema i nā chromosomes 1, 14, a me 21, nona ka ʻike genetic i loko o ko mākou kino. Eia kekahi, ʻoi aku ka nui o ka pilikia o ka poʻe me Down syndrome i ka loaʻa ʻana o kēia ʻano maʻi Alzheimer.
ʻO ka maʻi Alzheimer i ka wā lohi
ʻO kēia ke ʻano maʻamau o ka maʻi Alzheimer a kākou a pau i ʻike ai. Hoʻomaka ka ʻike ʻia ʻana o nā hōʻailona ma hope o ka piha ʻana o 65 mau makahiki. I kekahi manawa hiki ke holo i loko o nā ʻohana. ʻO ia hoʻi, inā loaʻa i kahi makuahine, hiki i kāna keiki ke pilikia. Akā, he gene kikoʻī, e like me ke ʻano e ulu ana i ka wā ʻōpiopio,ʻAʻole i ʻike ʻia ke kumu kikoʻī o kēia maʻi. No laila, ke noiʻi nei nā kauka a me nā ʻepekema i ke kumu e loaʻa ai i kekahi poʻe a ʻaʻole kekahi.
He aha ka maʻi Alzheimer Familial (FAD)?
Aia kekahi mea e huikau ai ka poʻe he nui ma ʻaneʻi. ʻO "Ua loaʻa i kekahi o ka ʻohana" a me "Familial Autism Spectrum Disorder (FAD)" he ʻelua mau mea like ʻole.
ʻO ka Maʻi Alzheimer ʻOhana (FAD) kahi kūlana i maopopo loa i nā kauka he 100% ke kumu o nā kumu hoʻoilina. I mea e ʻike ʻia ai me ia, pono i ʻelua mau hanauna o ka ʻohana (no ka laʻana, he kupuna wahine a me kahi makuahine) ke loaʻa i ka maʻi. He mea kākaʻikahi loa ia, ʻaʻole i hiki i ka 1% o nā maʻi Alzheimer āpau. ʻO ka hapa nui o ka poʻe i loaʻa iā Alzheimer i ka wā ʻōpiopio he ʻano FAD kēia.
Inā ʻoe a i ʻole kekahi o kou ʻohana e loaʻa ana i nā pilikia hoʻomanaʻo, mai manaʻo wale, "He mea kahiko wale nō kēia" a i ʻole "he moʻolelo ʻohana wale nō." He maʻi hiki ke mālama ʻia. No laila, ʻo ka mea maikaʻi loa e hana ai, ʻo ia ke ʻike koke i kāu kauka a loaʻa kahi hōʻailona kūpono.
Leka Lawe-Home
- Hiki i ka maʻi Alzheimer ke loaʻa i nā ʻano like ʻole. Hoʻokumu nui ʻia kēia hoʻokaʻawale ʻana ma muli o ka makahiki i hoʻomaka ai ka maʻi (hoʻomaka mua a me ka hoʻomaka hope).
- He mea kākaʻikahi loa ke ʻano hoʻomaka mua, ka mea e ulu ana i nā poʻe ma lalo o 65 mau makahiki. He pilina hoʻoilina ikaika kona.
- ʻAʻole i loaʻa kahi kumu genetic kikoʻī no ke ʻano hoʻomaka lohi a mākou e ʻike pinepine ai, ka mea e ulu ana ma hope o 65 mau makahiki.
- Mai manaʻo ʻoe e loaʻa pū ana iā ʻoe ka maʻi Alzheimer no ka mea he maʻi ko kekahi o kou ʻohana. Akā, he mea nui e makaʻala i ka pilikia.
- I ke ʻano o kekahi pilikia e pili ana i ka hoʻomanaʻo, he kōkua nui ka ʻimi koke ʻana i ka ʻōlelo aʻo lapaʻau ma mua o ka hoʻowahāwahā ʻana iā ia no ka mea maʻi a me ka ʻohana.
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