ʻO ke kanaka e noho ana me ka maʻi Parkinson i kekahi manawa e nalowale koke ke kaohi o ko lākou neʻe ʻana o ke kino, lilo ko lākou kino i ʻoʻoleʻa , a hoʻomaka lākou e haʻalulu. Kāhea mākou i kēia he hanana 'off'. Me he mea lā ua 'pani ʻia' kahi kuapo. No laila i kēia lā e kamaʻilio mākou e pili ana i kahi lāʻau lapaʻau kūikawā i hoʻohana ʻia e hāʻawi i ka hōʻoluʻolu wikiwiki i nā manawa e like me kēia. ʻO ia kahi papa sublingual i kapa ʻia ʻo apomorphine.
He aha kēia ʻApomorphine?
I ka ʻōlelo maʻalahi, he lāʻau lapaʻau kēia i hāʻawi ʻia e kāohi i nā hōʻailona o ka maʻi Parkinson. Kōkua kahi kemika i kapa ʻia ʻo dopamine i ka hoʻokele ʻana i ka neʻe ʻana a me ka hoʻonohonoho ʻana i loko o ko kākou lolo. E noʻonoʻo i kēia dopamine ma ke ʻano he ʻelele e kāohi ana i nā neʻe ʻana o ko kākou kino. I ka maʻi Parkinson, emi ka nui o kēia ʻelele i loko o ka lolo. ʻO ia ka manawa e ʻike ʻia ai nā hōʻailona e like me ka haʻalulu a me ka ʻoʻoleʻa .
No laila, ʻo ka hana a kēia lāʻau lapaʻau, ʻo Apomorphine, e like me ka ʻelele dopamine i hoʻopau ʻia a kōkua i ka lolo e hoʻouna hou i nā leka me ke kūpono. ʻO ka hopena, ua emi koke nā hōʻailona o Parkinson a ua ʻoluʻolu iki ke kino.
Aia nō hoʻi kēia lāʻau lapaʻau ma lalo o ka inoa inoa ʻo KYNMOBI. Eia nō naʻe, no ka mea hiki ke hoʻohana ʻia no nā mea ʻē aʻe, ʻoi aku ka maikaʻi o ke kamaʻilio ʻana me kāu kauka e pili ana i nā hopohopo āu e loaʻa ai.
Nā mea e pono ai ʻoe e haʻi i kāu kauka ma mua o ka lawe ʻana i kēia lāʻau lapaʻau
He mea nui loa i kāu kauka ke ʻike i kāu mōʻaukala olakino piha ma mua o ke kau ʻana i kēia lāʻau. E hōʻoia e haʻi i kāu kauka inā loaʻa iā ʻoe kekahi o nā kūlana i helu ʻia ma lalo nei.
- Inā loaʻa iā ʻoe ka poniuniu pinepine a i ʻole ka māʻule ʻana: Hiki i kēia lāʻau lapaʻau ke hoʻohaʻahaʻa i ke koko. No laila, inā loaʻa iā ʻoe kēia pilikia, he mea nui e haʻi aku.
- Maʻi puʻuwai: Inā loaʻa iā ʻoe ka maʻi puʻuwai, ʻoiai nā puʻuwai puʻuwai kūpono ʻole.
- Ke koko haʻahaʻa: Inā haʻahaʻa kou koko.
- Inā ua loaʻa iā ʻoe kahi hahau.
- Maʻi puʻupaʻa a i ʻole ke akepaʻa: Inā ʻaʻole hana pono kou mau puʻupaʻa a i ʻole ke akepaʻa.
- Nā maʻi o ka māmā: Nā pilikia hanu e like me ka hānō.
- Nā pilikia olakino noʻonoʻo: Nā kūlana e like me ke kaumaha.
- Inā ʻike ʻoe i ka hiamoe hiki ʻole ke kāohi i ke ao.
- Inā he mea inu pinepine ʻoe.
- Inā ʻoe e hāpai ana a i ʻole e hoʻāʻo ana e hāpai.
- Inā he makuahine ʻoe e hānai waiū ana.
- Inā he mau maʻi ʻē aʻe kāu: E haʻi i kāu kauka inā he mau maʻi ʻē aʻe kāu i ka apomorphine, sulfites, nā lāʻau lapaʻau ʻē aʻe, nā meaʻai, nā mea mālama, a i ʻole nā mea hoʻoluʻu.
He mea nui loa ia no kou palekana ponoʻī e haʻi i ke kauka me ka hūnā ʻole i kēia ʻike.
Pehea pololei ʻoe e hoʻohana ai i kēia lāʻau lapaʻau?
He maʻalahi loa ke ʻano e hoʻohana ai i kēia, akā pono e hana pono ʻia.
1. E lawe i ka manawa kūpono: E hoʻohana i kēia i ka wā e loaʻa ai iā ʻoe kahi hanana 'off', e like me ka ʻōlelo a kāu kauka iā ʻoe.
2. Wehe mai loko mai o ka ʻeke: E mālama i ka lāʻau lapaʻau i loko o ka ʻeke pepa kini a hiki i kou mākaukau e lawe.
3. Pono nā lima e maloʻo: E hōʻoia i ka maloʻo o kou mau lima ma mua o ka lawelawe ʻana i ka lāʻau. Hiki ke heheʻe inā ʻoe e hoʻopā me nā lima pulu.
4. E kau i ke kiʻiʻoniʻoni ma lalo o kou alelo: E kau i ke kiʻiʻoniʻoni ma lalo o kou alelo a e ʻae iā ia e heheʻe a komo i loko o kou kino.
5. Mai nau, uhaʻi, a wili paha: Mai nau, uhaʻi, a wili paha i kēia lāʻau lapaʻau i loko o kou waha. Pono ia e hoʻoheheʻe ʻia ma lalo o kou alelo.
Mai ho'ōki koke i ka lawe ʻana i kēia lāʻau lapaʻau me ka ʻole o ke kūkākūkā ʻana me kāu kauka. Hiki i kēia ke hana i nā hopena ʻaoʻao koʻikoʻi a hiki ke hoʻonui i kou kūlana.
He aha ka mea e hana ai inā ʻoe e lawe i ka overdose?
Inā manaʻo ʻoe ua lawe nui ʻoe i kēia lāʻau lapaʻau, mai hopohopo. E hele koke i ka Halemai Pilikia (ETU) kokoke loa . A i ʻole, e kelepona i ke Kikowaena ʻIke ʻAi ʻona Lahui ma ka Halemai Lahui ʻo Colombo .
He aha inā e hala wau i kahi lāʻau?
ʻAʻole kēia he lāʻau lapaʻau e lawe ʻia i ka manawa like i kēlā me kēia lā. Hoʻohana wale ʻia ia i nā wā 'off' episodes, i ka wā e piʻi koke ai nā hōʻailona o Parkinson. No laila, ʻaʻole pili ka 'missed a dose' ma ʻaneʻi. Eia nō naʻe, inā ʻoe e lawe i ka mahele mua i ka wā 'off' episode a ʻaʻole i hoʻomaikaʻi kāu mau hōʻailona, mai lawe i ka lua o ka mahele i kēlā manawa. E kamaʻilio me kāu kauka e pili ana i kēia.
Nā lāʻau lapaʻau ʻē aʻe e launa pū me kēia lāʻau lapaʻau
He ʻāpana koʻikoʻi loa kēia. Hiki i kekahi mau lāʻau lapaʻau ke hana i nā hopena weliweli ke lawe ʻia me Apomorphine.
| Mai lawe pū me ia i kēia lāʻau lapaʻau! | |
|---|---|
| ʻO Cisapride | Pimozide |
| ʻO Dronedarone | ʻO Thioridazine |
| ʻO Ketoconazole | ʻO Levoketoconazole |
| ʻO kekahi mau lāʻau lapaʻau no ka luaʻi ʻana a me ka nausea (e.g., dolasetron, granisetron, ondansetron, palonosetron) | |
| E akahele loa i ka wā e hoʻohana ai i kēia mau mea me | |
|---|---|
| ʻAila | Nā lāʻau hiamoe |
| ʻO kekahi mau lāʻau lapaʻau no ke kaumaha (e like me ka amitriptyline) | Mea hoʻomaha ʻiʻo |
| ʻO kekahi mau opioids no ka ʻeha a i ʻole ke kuni | ʻO ka nitroglycerin |
| ʻO kekahi mau lāʻau lapaʻau no nā maʻi allergies (Antihistamine) | Nā lāʻau lapaʻau e like me Haloperidol a me Metoclopramide |
ʻAʻole i piha kēia papa inoa, no laila e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei (me nā huaora, nā lāʻau lapaʻau kuʻuna, nā lāʻau lapaʻau lāʻau, a me nā mea hoʻohui lāʻau) .
Nā mea e makaʻala ai i ka wā e lawe ai i kēia lāʻau lapaʻau
- Ka luaʻi a me ka luaʻi: Hiki i kēia lāʻau lapaʻau ke hoʻoulu i ka luaʻi a me ka luaʻi. I kekahi manawa hiki ke koʻikoʻi loa. E kuhikuhi kāu kauka i kahi lāʻau lapaʻau ʻokoʻa no kēia. Mai lawe i nā lāʻau lapaʻau anti-nausea ma luna o ke kūʻai aku. ʻAʻole kūpono nā lāʻau lapaʻau anti-nausea āpau me kēia lāʻau.
- Hiamoe koke:He mea nui loa kēia. Ke lawe ʻoe i kēia lāʻau lapaʻau, hiki iā ʻoe ke hiamoe koke me ka ʻole o ka ʻōlelo aʻo. E noʻonoʻo ʻoe e hoʻokele ana i kahi kaʻa, e ʻai ana, a e kamaʻilio ana paha me kekahi a hiamoe ʻoe me ka ʻike ʻole. He mea weliweli loa kēia. No laila , mai hoʻokele a hoʻohana paha i nā mīkini a hiki i kou ʻike ʻana i ke ʻano o ka hopena o kēia lāʻau lapaʻau iā ʻoe. Inā loaʻa iā ʻoe kēia, e haʻi koke i kāu kauka.
- ʻAila: ʻO ka lawe ʻana i kēia lāʻau lapaʻau me ka waiʻona e hoʻonui nui i ka pilikia o ka poniuniu, ka nāwaliwali, a me ka hiamoe koke.
- Nitroglycerin: Inā ʻoe e lawe ana i ka nitroglycerin ma ke ʻano sublingual no kahi maʻi puʻuwai, ʻo ka lawe pū ʻana i kēia mau lāʻau ʻelua hiki ke hoʻohaʻahaʻa i ke koko. No laila, inā pono ʻoe e lawe i ka nitroglycerin, e moe mua . A laila e lawe i ka lāʻau. E noho moe no 45 mau minuke ma hope o ka lawe ʻana i ka lāʻau.
He aha nā hopena ʻaoʻao e hiki ke ʻike ʻia?
E like me nā lāʻau lapaʻau āpau, hiki i kēia ke loaʻa nā hopena ʻaoʻao. He koʻikoʻi kekahi, he mea maʻamau kekahi.
| Nā hopena ʻaoʻao koʻikoʻi e pono e hōʻike koke ʻia i ke kauka | |
|---|---|
| Nā hopena alerika | ʻŌhūhū ʻili, maneʻo, pehu o ka maka, nā lehelehe, ke alelo, nā maka, paʻakikī i ka hanu ʻana a i ʻole ke ale ʻana. |
| Hiamoe koke | Ka hiamoe ʻana i ke ao me ka ʻole o ka ʻōlelo aʻo . |
| Ke koko haʻahaʻa | Pōʻino nui, maule, ʻike pōwehiwehi. |
| Nā loli i ka helu o ka puʻuwai | Manaʻo e like me ka wikiwiki o kou puʻuwai a i ʻole ke kuʻi ʻano ʻole, ʻeha ka umauma, paʻakikī ka hanu ʻana. |
| Nā loli noʻonoʻo | ʻIke a lohe paha i nā mea i ʻike ʻole ʻia (hallucinations), nā loli maʻamau ʻole i ke ʻano. |
| Nā impulses hiki ʻole ke kāohi ʻia | Nā makemake kaohi ʻole e komo i nā hana e like me ka piliwaiwai, ka ʻai nui ʻana, ka moekolohe, a me ka hoʻolilo kālā pono ʻole. |
| ʻAʻai koko hemolytic | Manaʻo luhi loa, poniuniu, pilikia ka hanu ʻana, mimi ʻeleʻele, melemele o ka ʻili a i ʻole nā maka. |
| Nā hopena ʻaoʻao i ʻike pinepine ʻia, akā pono e hōʻike ʻia i ke kauka inā hoʻomau lākou | |
| Pōʻino | Hiamoe |
| ʻEha poʻo | Ka luaʻi a me ka luaʻi |
| Ma kahi o ka lāʻau lapaʻau, ʻo ia hoʻi, ma lalo o ke alelo, aia ka ʻeha, ka mumū, a i ʻole ka ʻehaʻeha. | |
Pehea e mālama ai i ka lāʻau lapaʻau?
- E mālama ʻia mai nā keiki a me nā holoholona. He mea nui loa kēia.
- E mālama ma ka mahana o ka lumi (ma waena o 20-25 kekelē Celsius).
- E mālama i ka lāʻau lapaʻau i loko o ka ʻeke foil a hiki i ka wā e hoʻohana ai.
- E hoʻolei aku i ka lāʻau lapaʻau i pau ka lā.
E nīnau i kāu kauka pehea e hoʻolei palekana ai i nā lāʻau lapaʻau i hoʻohana ʻole ʻia a i pau paha.
Leka Lawe-Home
- He papa sublingual ʻo Apomorphine e hāʻawi ana i ka kaohi wikiwiki ʻana i nā hōʻailona i nā wā 'off' o ka maʻi Parkinson.
- Ma mua o ka hoʻohana ʻana i kēia lāʻau lapaʻau, e haʻi i kāu kauka e pili ana i kou mau kūlana olakino a me nā lāʻau lapaʻau ʻē aʻe āu e lawe nei.
- Hiki paha iā ʻoe ke hiamoe me ka ʻike ʻole i ka wā e lawe ana i kēia lāʻau lapaʻau. No laila, e pale i nā hana e pono ai ka makaʻala, e like me ka hoʻokele kaʻa ʻana, a hiki i kou ʻike ʻana i ka hopena o kēia lāʻau lapaʻau i kou kino.
- I mea e hōʻemi ai i ka poniuniu a me ka māʻule ʻana, e ala pinepine i luna i ka wā e noho ana a moe paha.
- E makaʻala i nā hopena ʻaoʻao koʻikoʻi (e like me nā maʻi allergies, nā loli o ka puʻuwai, nā loli noʻonoʻo) e pono ai ke kōkua koke ʻia e ke kauka.
- Nou wale nō kēia lāʻau lapaʻau. Mai kaʻana like me nā poʻe ʻē aʻe.
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