Ke manaʻo nei ʻoe i kekahi manawa i ka luhi maʻamau, piʻi ke kaumaha me ke kumu ʻole, a i ʻole hopohopo nui a kaumaha? ʻOiai ke manaʻo pinepine nei mākou he mau mea maʻamau kēia, nā mea e hana ʻia ma muli o nā pilikia o kēlā me kēia lā, aia paha kekahi mau loli i loko o ka 'hormone stress' i kapa ʻia ʻo cortisol i loko o ko mākou kino ma hope o kēia. No laila, inā ʻike kāu kauka i kēia mau hōʻailona, e paipai paha ʻo ia e hana i kēia hoʻāʻo cortisol. I kēia lā, e kamaʻilio kākou e pili ana i ke ʻano o kēia hoʻāʻo cortisol, no ke aha i hana ʻia ai, a me nā mea hiki iā ia ke haʻi iā ʻoe.
ʻO ka mea mua, he aha ka cortisol?
I ka ʻōlelo maʻalahi, he hormone koʻikoʻi ka cortisol i loko o ko kākou kino. Hana ʻia ia e ʻelua mau kelepa liʻiliʻi ma luna o ko kākou mau puʻupaʻa, ʻo ia hoʻi nā kelepa adrenal. Ua ʻike mākou a pau i kēia ʻo ka 'hormone stress'. E noʻonoʻo, i ka wā e kū ai mākou i kahi pōʻino koke, kaomi, a makaʻu paha, ʻo ia ka hormone cortisol e hāʻawi i ko mākou kino i ka ikaika a me ka hoʻomākaukau e pono ai e kū i mua.
Akā, ʻaʻole i pau ka hana a cortisol ma laila. He nui kāna mau hana koʻikoʻi ʻē aʻe.
- Ke kāohi nei i ke koko.
- Kōkua i ka mālama ʻana i nā pae kō koko.
- ʻO ka metabolism o ko kākou kino, ʻo ia ke kaʻina hana e wāwahi ʻia ai ka meaʻai a kākou e ʻai ai i nā kalapona, nā protein, a me nā momona a hoʻololi ʻia i ikehu, kōkua ia.
- Ke kāohi nei i ka mumū i loko o ke kino.
- Ke kaohi nei i kā mākou pōʻaiapuni hiamoe-ala.
ʻIke ʻoe? ʻAʻole wale ka Cortisol e pili ana i ke kaumaha, he mea ia e pono ai no nā mea he nui i loko o ko kākou kino e hana pono ai.
He aha nā hōʻailona o ke kiʻekiʻe o ka cortisol?
Inā kiʻekiʻe loa kou pae cortisol, he hōʻailona paha ia o kahi maʻi i kapa ʻia ʻo Cushing's syndrome . Eia kekahi o nā hōʻailona āu e ʻike ai.
| Hōʻailona | Wehewehena |
|---|---|
| Piʻi koke ke kaumaha | Ka hōʻiliʻili ʻana o ka momona, ʻoiai ma ka ʻōpū, ka umauma, a me ka maka. |
| Maka poepoe | Pehu a poepoe ka maka. |
| He puʻu momona ma ke kua o ka ʻāʻī | Hoʻokumu ʻia ka puʻu momona e ka hōʻiliʻili ʻana o ka momona ma waena o nā poʻohiwi ma hope o ka ʻāʻī. |
| Nā loli ʻili | Ka lahilahi o ka ʻili, ka maʻalahi o ka palapū, a me ke ʻano o nā māka ʻōniʻoniʻo poni ma nā wahi e like me ka ʻōpū a me nā ʻūhā. |
| Ke koko kiʻekiʻe a me ka maʻi diabetes | Hoʻonui ʻia ke koko a me nā pae kō koko. |
| Nā hiʻohiʻona ʻē aʻe | Ka nāwaliwali o nā ʻiʻo, ka nāwaliwali o ka iwi, ke kaumaha, ka hopohopo, a me nā pōʻaiapuni menstrual ʻano ʻole i nā wahine. |
He aha nā kumu o ka hoʻonui ʻia o ka cortisol?
- Nā lāʻau steroid: Ke lawe nei i nā lāʻau steroid he nui e like me dexamethasone a i ʻole prednisolone no ka manawa lōʻihi no nā maʻi ʻē aʻe (e like me ka hānō, ka rheumatoid arthritis).
- ʻO ka puʻupuʻu pituitary gland: He puʻupuʻu i loko o ka pituitary gland, aia ma ke kumu o ko mākou lolo a ua like ia me ka master gland e kaohi ana i nā glands hormonal ʻē aʻe i loko o ke kino.
- ʻO ka puʻupuʻu kelepa adrenal: He puʻupuʻu a i ʻole ka ulu ʻana maʻamau ʻole i loko o ke kelepa ponoʻī, ka mea e hana ai i ka cortisol.
He aha ka mea e hana ai inā hāʻule nā pae cortisol?
Inā lilo nā pae cortisol i haʻahaʻa loa, hiki iā ia ke lilo i hōʻailona o kahi maʻi i kapa ʻia ʻo ka maʻi ʻo Addison . Eia nā hōʻailona.
- Luhi mau
- Pōʻino
- Ka emi ʻana o ke kaumaha
- Ke koko haʻahaʻa
- ʻO ke kala ʻeleʻele a ʻeleʻele paha o ka ʻili ma nā wahi
He aha nā kumu o ka cortisol haʻahaʻa?
- ʻO ka maʻi ʻo Addison: ʻO kēia ka manawa e hoʻouka ai ka ʻōnaehana pale o ko mākou kino ponoʻī a luku i kā mākou mau kelepa adrenal me ke kumu ʻole.
- Ka pōʻino o ke kelepa adrenal: Ka pōʻino o kēia mau kelepa ma muli o kahi maʻi a i ʻole kekahi kumu ʻē aʻe.
- ʻO ka hana ʻino ʻana o ke kelepa pituitary: Ke hana pono ʻole ka 'haku', ʻaʻole loaʻa i nā kelepa adrenal ka hōʻailona e hana i ka cortisol.
- Ke hoʻōki koke ʻana i nā steroids: He mea nui loa kēia. Inā ua lōʻihi kou lawe ʻana i nā steroids no kahi maʻi, hiki i ka hoʻōki koke ʻana iā lākou ke hoʻohaʻahaʻa i kāu mau pae cortisol. E hoʻōki mau i ka lawe ʻana i ka lāʻau lapaʻau ma lalo o ka nānā ʻana a kāu kauka, e hoʻēmi mālie ana i ka nui.
He aha nā ʻano hoʻāʻo cortisol i loaʻa?
Inā kauoha kāu kauka i kahi hoʻāʻo e nānā i kāu mau pae cortisol, aia ʻekolu mau ala nui e hana ai.
1. Hoʻāʻo Koko: ʻO kēia ke ʻano maʻamau. ʻOiai ke ʻokoʻa nei nā pae cortisol i ke ao holoʻokoʻa (kiʻekiʻe loa i ke kakahiaka, haʻahaʻa loa i ka pō), e noi paha kāu kauka iā ʻoe e lawe i ʻelua mau hāpana koko, ʻo kekahi ma kahi o 8 am a ʻo kekahi ma kahi o 4 pm. E kōkua kēia iā ʻoe e ʻike i ke ʻano o kāu mau pae cortisol i kēlā mau manawa.
2. Hoʻāʻo ʻana i ka lawai: Hana pinepine ʻia kēia i ka pō ma mua o ka hiamoe ʻana, ma waena o ka hola 11 a me ka hola 12 o ke aumoe. ʻO kēia no ka mea ʻo ka pae cortisol o ke kanaka olakino e pono ke haʻahaʻa loa i kēlā manawa. Inā kiʻekiʻe mau nā pae cortisol i kēlā manawa, he kumu kūpono ia e kānalua ai i kahi maʻi e like me ka Cushing's syndrome. E hāʻawi kāu kauka iā ʻoe i kahi pahu kūikawā no kēia.
3. Hoʻāʻo Mimi: I kekahi manawa e noi paha kāu kauka iā ʻoe e hōʻiliʻili i kāu mimi āpau i loko o 24 mau hola a hoʻāʻo iā ia. Ua kapa ʻia kēia he "hoʻāʻo mimi 24 hola." ʻOiai hiki ke lilo i mea hoʻoluhi iki, hāʻawi kēia ʻano hana iā ʻoe i ka manaʻo maikaʻi loa o ka nui o ka "cortisol manuahi" a kou kino e hana ai i ka lā a pau.
Pono e hana mau ʻia ka wehewehe ʻana i ka hopena o ka hoʻāʻo cortisol me kāu kauka. Mai hoʻokumu i kāu mau hoʻoholo ma ka ʻike i loaʻa ma ka pūnaewele wale nō.
Nā hoʻokolohua kūikawā ʻē aʻe i hana ʻia me kēia hoʻokolohua
I kekahi manawa, no ka ʻike ʻana i ke kumu pololei o nā pae cortisol haʻahaʻa a kiʻekiʻe paha, hiki i kāu kauka ke kuhikuhi i kekahi mau hoʻokolohua kūikawā hou aʻe.
- Hoʻāʻo Hoʻoulu ACTH: Hoʻāʻo kēia i ke ʻano o ka pane ʻana o kāu mau kelepa adrenal i ke 'kauoha' (ka hormone `ACTH`) mai kāu kelepa pituitary. Ua like ia me kahi luna e nānā ana inā hana kahi limahana i ka mea kūpono ke noi ʻia e hana i kekahi mea. Hana kūikawā ʻia kēia e ʻike i ke kumu o nā pae cortisol haʻahaʻa.
- Hoʻāʻo Hoʻopau Dexamethasone:Ua like kēia me kekahi ʻaoʻao o kēlā hoʻāʻo. Nānā ia inā ua kāohi ʻia nā pae cortisol kiʻekiʻe i loko o ke kino ma ka hāʻawi ʻana i kahi liʻiliʻi o ka lāʻau steroid i kapa ʻia ʻo "(dexamethasone)". Kōkua kēia i ka ʻike ʻana inā loaʻa iā ʻoe ka Cushing's syndrome a inā paha i hoʻokumu ʻia e kahi puʻupuʻu ma ka pituitary gland a i ʻole ma kahi ʻē aʻe.
Inā manaʻo kāu kauka i kahi mea e like me ka puʻupuʻu, hiki iā ia ke kuhikuhi iā ʻoe no kahi CT scan a i ʻole MRI scan.
Nā kumu ʻē aʻe e hiki ai i nā hopena ke ʻano ʻē
He mau maʻi kakaikahi ka maʻi Cushing a me ka maʻi Addison. Aia kekahi mau kumu maʻamau o nā pae cortisol maʻamau ʻole.
- Kaumaha nui
- Hoʻoikaika kino nui
- Hāpai keiki
- Momona
- ʻO kekahi mau lāʻau lapaʻau, e like me nā pila hoʻomalu hānau
No laila, mai makaʻu i ka loli koke o ka hopena. E noʻonoʻo kāu kauka i kēia mau mea a pau a haʻi iā ʻoe i ke kumu maoli.
Leka Lawe-Home
- ʻAʻole wale ʻo Cortisol ka 'hormone stress' o ko mākou kino, akā he hormone koʻikoʻi hoʻi e kaohi i ke koko, nā pae kō, a me ka metabolism.
- ʻOkoʻa nā pae Cortisol ma muli o ka manawa o ke ao. ʻOi aku ke kiʻekiʻe i ke kakahiaka a haʻahaʻa i ka pō.
- Hiki i nā pae cortisol kiʻekiʻe loa ke lilo i hōʻailona o ka maʻi Cushing. Hiki i nā pae haʻahaʻa loa ke lilo i hōʻailona o ka maʻi Addison.
- ʻO ke kaumaha, ka hoʻoikaika kino, ka hāpai ʻana, a me kekahi mau lāʻau lapaʻau hiki ke hana i nā loli i nā pae cortisol.
- Inā pono ʻoe e lawe i kahi hoʻāʻo cortisol, e kūkākūkā mau i nā hopena me kāu kauka. E hāʻawi ʻo ia iā ʻoe i ke alakaʻi maikaʻi loa.
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