Ua noʻonoʻo paha ʻoe pehea e hele ai ka ʻike i mua a i hope i loko o ko kākou lolo? Ua like ia me kahi hui o nā ʻelele liʻiliʻi e hana pū ana e hana i kahi hana kupaianaha. Kāhea mākou i kēia mau ʻelele he mau neurotransmitters. I kekahi manawa, ma muli o kekahi mau kūlana olakino, hiki i kēia hoʻololi leka ke lilo i mea huikau iki. ʻO ia ka manawa e kōkua mai ai kekahi mau lāʻau lapaʻau iā mākou. I kēia lā e kamaʻilio mākou e pili ana i kekahi ʻano o nā lāʻau lapaʻau, i kapa ʻia ʻo dopamine antagonists.
I ka ʻōlelo maʻalahi, he aha kēia mau mea kū'ē i ka dopamine?
I mea e hoʻomaopopo ai i kēia, pono mua kākou e ʻike i ke ʻano o ka dopamine. He neurotransmitter koʻikoʻi loa ka Dopamine i loko o ko kākou lolo. Kōkua ia i ka hoʻomalu ʻana i nā mea he nui, me ko kākou mau manaʻo, nā manaʻo, a me nā neʻe ʻana.
I kēia manawa, e noʻonoʻo ʻoe he mau 'loka' liʻiliʻi ko ko kākou mau pūnaewele lolo. Kāhea mākou i kēia mau mea he 'nā mea loaʻa'. Ua like ka dopamine messenger me he 'kī' lā. Ke komo kēia kī i loko o kēlā laka (mea loaʻa), e 'hoʻāla' ʻia kēlā pūnaewele, ʻo ia hoʻi, hoʻomaka ia e hana i kāna hana.
ʻAe, he aha ka hana a kahi lāʻau i kapa ʻia he 'dopamine antagonist'? Ua like kēia lāʻau me kahi 'kī hoʻopunipuni' hiki iā ʻoe ke hoʻokomo i loko o kēlā laka, akā ʻaʻole hiki iā ʻoe ke wehe i ka laka. ʻO ia hoʻi, hele kēia lāʻau i loko o ka laka `(receptor)` e pono ai ka dopamine e hoʻonohonoho, a `(ālai)` ia.
I mea e maʻalahi ai, e noʻonoʻo i kahi noho ma kahi pāʻina me kahi kāleka e ʻōlelo ana 'Reserved' ma luna. ʻAʻohe mea e noho ana ma laila, akā ʻaʻole hiki iā ʻoe ke noho ma laila, ʻeā? Pēlā ka hana a kēia lāʻau. Mālama ia i ka dopamine receptor i ka hana ʻole, e pale ana i ka dopamine maoli mai ke komo ʻana mai a hoʻāla iā ia.
Ma muli o kona kaohi ʻana i ka hoʻāla ʻana o kekahi mau hunaola lolo ma kēia ʻano, he mea pono loa kēia lāʻau lapaʻau i ka kaohi ʻana i kekahi mau maʻi noʻonoʻo a me nā hōʻailona ʻē aʻe.
He aha nā kūlana e hoʻohana ʻia ai kēia lāʻau lapaʻau?
Hiki ke hoʻokaʻawale ʻia nā lāʻau lapaʻau antagonist Dopamine i ʻelua mau māhele nui, akā aia kekahi mau hihia kahi e hana ai kekahi mau lāʻau lapaʻau ma nā māhele ʻelua.
1. Nā lāʻau lapaʻau antipsychotic: Nā lāʻau i hoʻohana ʻia e mālama i ka psychosis a me nā kūlana pili.
2. Nā lāʻau hoʻēmi i ka luaʻi: Nā lāʻau lapaʻau i hāʻawi ʻia e hoʻōki i ka nausea a me ka luaʻi ʻana.
E nānā kākou i nā maʻi nui i mālama ʻia me kēia mau lāʻau lapaʻau.
| Māhele lāʻau lapaʻau | Nā kūlana i mālama ʻia |
|---|---|
| Nā lāʻau lapaʻau antipsychotic |
|
| Nā lāʻau antiemetic |
|
He aha nā ʻano lāʻau lapaʻau e pili ana i kēia mau māhele?
Nui nā ʻano lāʻau lapaʻau e hāʻule ana i loko o kēia mau māhele. ʻO ka maʻamau, ua māhele ʻia nā lāʻau antipsychotic no ka maʻi noʻonoʻo i ʻelua "hanauna." ʻO ia hoʻi, nā lāʻau lapaʻau kahiko i ʻike mua ʻia (hanauna mua) a me nā lāʻau lapaʻau hou i ʻike ʻia ma hope, me nā hopena ʻaoʻao liʻiliʻi (hanauna ʻelua).
Nā lāʻau lapaʻau hanauna mua (Maʻamau)
Eia kekahi o nā lāʻau lapaʻau kahiko. ʻO kekahi o lākou:
- ʻO Chlorpromazine
- ʻO Haloperidol (Haldol®)
- ʻO ka Fluphenazine
- ʻO ka Perphenazine
- ʻO ka Prochlorperazine
Nā lāʻau lapaʻau hanauna ʻelua (Atypical)
He mau lāʻau lapaʻau hou kēia.
- ʻOlanzapine (Zyprexa®)
- ʻO Risperidone (Risperdal®)
- ʻO Quetiapine (Seroquel®)
- ʻAripiprazole (Abilify®)
- ʻO Clozapine (Clozaril®)
Nā lāʻau antiemetic no ka nausea a me ka luaʻi
Ua ʻike paha ʻoe i kekahi o kēia mau lāʻau lapaʻau i helu ʻia ma luna nei ma ka papa inoa o nā maʻi noʻonoʻo. ʻO ke kumu, hiki iā lākou ke hana i kēia mau mea ʻelua.
- ʻO ka Metoclopramide (Reglan®)
- ʻO ka Prochlorperazine
- ʻOlanzapine
- ʻO Haloperidol
- ʻO `Domperidone` (ʻAʻole i loaʻa nui kēia lāʻau lapaʻau ma Sri Lanka, a hiki ke loaʻa me ka ʻae kūikawā wale nō)
Mea nui: He mau laʻana wale nō kēia. ʻAʻole paha i kuhikuhi kāu kauka i ka lāʻau lapaʻau ma kēia papa inoa. Mai hoʻohana i ka lāʻau lapaʻau a haʻi, e hoʻōki i ka lawe ʻana, a i ʻole e hoʻololi i ka nui me ka ʻole o ka ʻōlelo aʻoaʻo a kāu kauka.
He aha nā pono o kēia mau lāʻau lapaʻau?
He papa lāʻau lapaʻau pono loa nā mea hoʻopilikia Dopamine.
No ka maʻi noʻonoʻo:
No kekahi kanaka me ke ʻano e like me ka psychosis, hiki i kēia lāʻau lapaʻau ke hoʻōla i ke ola . Hiki iā ia ke hōʻemi i ka pilikia o ka poʻe me kēia mau kūlana e hōʻeha iā lākou iho a i ʻole e hana ʻino ʻia e kekahi poʻe ʻē aʻe. Hiki iā ia ke hāʻawi iā lākou i kahi manawa kūpono e ola ai i kahi ola maʻamau, hana, a hauʻoli me ko lākou mau ʻohana.
No ka nausea a me ka luaʻi ʻana:
No mākou, he mea hoʻopilikia wale nō paha ka luaʻi ʻana e nalowale ana ma hope o kekahi manawa. Akā e noʻonoʻo e pili ana i kahi maʻi kanesa. ʻO ka nausea a me ka luaʻi a lākou e ʻike ai i ka wā chemotherapy he koʻikoʻi loa ia a hiki ke hoʻoweliweli i ke ola. I nā manawa e like me kēia, ke hana ʻole nā lāʻau lapaʻau ʻē aʻe, hiki i kēia mau lāʻau antagonist dopamine ke lawe mai iā lākou i ka hōʻoluʻolu nui.
Aia kekahi mau hopena ʻaoʻao a i ʻole nā pilikia?
ʻAe, e like me nā lāʻau lapaʻau ʻē aʻe, hiki i kēia mau lāʻau lapaʻau ke loaʻa nā hopena ʻaoʻao. Akā, ʻaʻole i loaʻa i nā kānaka a pau kēia mau hopena ʻaoʻao a pau. Aia ia i nā mea he nui, e like me ka lāʻau lapaʻau āu e lawe ai, ka nui o ka lāʻau, a me ke ʻano o kou kino. ʻO ka mea nui loa, ʻaʻole ʻoe e makaʻu i kēia a kamaʻilio ākea me kāu kauka.
| Ka hopena ʻaoʻao hiki ke loaʻa | He wehewehe maʻalahi |
|---|---|
| Hoʻomaha | He mea maʻamau kēia i nā wā mua o ka lawe ʻana i ka lāʻau. E emi ana kēia i ka wā e maʻa ai ke kino i ka lāʻau. |
| Nā Maʻi Neʻe | - ʻAkatisia:Ke hoʻomaha ʻole o ka hiki ʻole ke noho ma kahi hoʻokahi, ka manaʻo o ka pono e neʻe mau a puni. - Dystonia: ʻūmiʻi koke nā ʻiʻo, ka ʻūmiʻi ʻana (e.g., ka neʻe ʻana o ka ʻāʻī i kekahi ʻaoʻao). - Tardive Dyskinesia: Nā neʻe ʻana o ka maka, ka waha, a i ʻole ke alelo i hiki ke hana me ka hoʻohana lōʻihi ʻana i ka lāʻau lapaʻau. |
| ʻO ke koko haʻahaʻa Orthostatic | Manaʻo ʻoe ua poniuniu a ʻālohilohi paha ke kū koke ʻoe mai ka noho ʻana a i ʻole ka moe ʻana. Hana ʻia kēia e ka emi koke ʻana o ke koko. |
| Nā Hoʻololi Hormonal | ʻO ka hoʻonui ʻia ʻana o ka hormone prolactin hiki ke hoʻōki i nā wāhine i kā lākou mau pōʻaiapuni menstrual a loaʻa kahi wai e like me ka waiū mai ko lākou mau umauma i ka wā ʻaʻole lākou e hānai waiū. |
| ʻO ka maʻi ʻino Neuroleptic | He kūlana laha ʻole kēia akā he mea hoʻoweliweli paha i ke ola. Inā loaʻa koke nā hōʻailona e like me ke kuni nui, ka ʻoʻoleʻa o nā ʻiʻo, a me ka nalowale o ka ʻike, pono ʻoe e hele koke i ka Emergency Treatment Unit (ETU) o ka haukapila. |
E haʻi aku kāu kauka iā ʻoe i nā mea hou aʻe e pili ana i kēia mau hopena ʻaoʻao a e aʻo iā ʻoe i ka mea hiki iā ʻoe ke hana e hōʻemi iā lākou.
ʻO kekahi mau nīnau ʻē aʻe paha āu e loaʻa ai
Pehea ka lōʻihi e pono ai iaʻu e lawe i kēia lāʻau lapaʻau?
Aia nō ia i ke kūlana āu e mālama ʻia nei. ʻO kekahi mau lāʻau lapaʻau, e like me nā lāʻau anti-nausea, lawe wale ʻia ke pono. Akā, pono paha e lawe ʻia nā lāʻau lapaʻau no ka maʻi noʻonoʻo no nā makahiki, a i ʻole no ke koena o kou ola. Na kāu kauka e hoʻoholo pololei i ka lōʻihi o kou lawe ʻana iā lākou.
Hiki iaʻu ke hana a hoʻokele paha i ka wā e lawe ana i kēia lāʻau lapaʻau?
He nīnau koʻikoʻi loa kēia. Hiki i kekahi o kēia mau lāʻau lapaʻau ke hoʻoulu i ka hiamoe nui a i ʻole ka luhi . No laila, pono ʻoe e nīnau i kāu kauka inā palekana ke hoʻokele a hoʻohana paha i nā mīkini i ka wā e lawe ana i kēia mau lāʻau lapaʻau. E hāʻawi ʻo ia iā ʻoe i ka ʻōlelo aʻoaʻo maikaʻi loa.
He papa lāʻau koʻikoʻi loa nā mea hoʻopilikia Dopamine i kōkua i ka hoʻomaikaʻi ʻana i ke ola o nā miliona. ʻOiai he mau hopena ʻaoʻao ko lākou, inā mālama pono ʻia ma lalo o ke alakaʻi a ke kauka, ʻoi aku ka nui o nā pono ma mua o lākou.
Leka Lawe-Home
- ʻO nā lāʻau lapaʻau i kapa ʻia ʻo dopamine antagonists e ālai i nā mea loaʻa i loko o ka lolo e loaʻa ana nā leka dopamine.
- Hoʻohana nui ʻia kēia mau mea e mālama i nā maʻi noʻonoʻo e like me ka psychosis a me ka nausea/luaʻi nui.
- ʻOiai he mau lāʻau lapaʻau maikaʻi loa kēia, hiki iā lākou ke hana i nā hopena ʻaoʻao e like me ka hiamoe a me nā pilikia neʻe.
- Mai hoʻomaka, hoʻōki, a hoʻololi paha i ka nui o kēia lāʻau lapaʻau me ka ʻole o ke aʻo a kāu kauka.
- Inā loaʻa iā ʻoe kekahi ʻano ʻoluʻolu ʻole i ka wā e hoʻohana ai i ka lāʻau lapaʻau, mai makaʻu e haʻi aku i kāu kauka.
💬 Comments (0)
ʻAʻohe manaʻo i kau ʻia. Hoʻohui i kāu manaʻo ma ʻaneʻi no ka manawa mua.
Hoʻohui i kāu manaʻo