Ua ʻike anei ʻoe i kēia puʻupuʻu (Granulosa Cell Tumor) e hana ʻia ana i loko o nā ovaries?

ʻAʻole paha ʻoe i lohe i kēia inoa ʻo 'Granulosa Cell Tumor'. He ʻano puʻupuʻu laha ʻole kēia e ulu ana i loko o nā ovaries. Akā he mea nui loa ia e ʻike e pili ana i ia mea, no ka mea hiki iā ia ke hoʻopilikia i kekahi o nā hormones i loko o ko mākou kino, ʻoi aku hoʻi i ke olakino o nā wahine. E kamaʻilio kākou e pili ana i kēia me nā kikoʻī.

He aha ka Granulosa Cell Tumor?

I ka ʻōlelo maʻalahi, he puʻupuʻu kūikawā kēia e ulu ana i loko o nā ovaries. Ua kapa ʻia e nā kauka ʻo "Sex Cord-Stromal Tumor". Ulu kēia mau puʻupuʻu i loko o nā ʻiʻo e hoʻopuni ana i nā ovaries. Hiki i kēia mau puʻupuʻu ke hana i ke kino e hana i ka nui o ka hormone wahine "(Estrogen)". ʻIke pinepine ʻia ia ma kahi o 50 mau makahiki, akā hiki ke ulu i kēlā me kēia makahiki.

Ma hea e hoʻokumu ʻia ai kēia mau puʻupuʻu?

Hoʻomohala pololei kēia `(Granulosa Cell Tumor)` i loko o nā ovaries. E like me kou ʻike, he ʻāpana koʻikoʻi loa nā ovaries o ka ʻōnaehana hānau wahine. Ma waho aʻe o ka hana ʻana i nā hua manu, hana pū nā ovaries i nā hormones hānau ʻelua `(Ova)` a me `(Estrogen)` a me `(Progesterone)`.

Pehea ka maʻamau o kēia mau mea?

Ua kapa ʻia kēia mau mea he "Granulosa Cell Tumors" a ʻaʻole lākou i maʻamau loa. He 5% wale nō lākou o nā "Primary Ovarian Tumors". He haʻahaʻa loa kēlā pakeneka.

He ʻino a he benign paha kēia mau puʻupuʻu?

ʻO ka hapa nui o ka manawa, ua manaʻo ʻia kēia mau puʻupuʻu, i kapa ʻia ʻo "Granulosa Cell Tumors", he mau maʻi ʻino. Akā ʻo ka nūhou maikaʻi, ulu lohi pinepine lākou. ʻO ia ke kumu e hiki ai i nā kauka ke ʻike iā lākou i ka wā mua. A laila maikaʻi loa nā hopena o ka lāʻau.

He aha ka ʻokoʻa ma waena o ka Granulosa Cell Tumor i nā pākeke a me nā ʻōpio?

ʻIke pinepine ʻia kēia mau puʻupuʻu i nā wāhine ʻelemakule. ʻO ka ʻoiaʻiʻo, 95% o nā hihia i hōʻike ʻia i nā wāhine ʻelemakule i ulu maikaʻi. Eia naʻe, inā ulu ia i loko o kekahi ma lalo o 30 makahiki, kapa mākou ia he "Juvenile GCT". Hiki i kēia "Juvenile GCT" ke hana hou i kahi wikiwiki iki ma mua o ka ulu ʻana i loko o kahi pākeke. Eia kekahi, inā ua pālahalaha ia ma waho o ka ovary a ʻike ʻia ma hope, hiki ke ʻoi aku ka koʻikoʻi.

No ke aha e ulu ai kēia (Granulosa Cell Tumor)? He aha ke kumu?

ʻAʻole i ʻike pono nā kauka i ke kumu o nā Granulosa Cell Tumors. Eia nō naʻe, ʻo ka hapa nui o ka poʻe me kēia mau tumors he mutation i loko o kahi gene i kapa ʻia ʻo ka gene FOXL2. ʻO kēia gene FOXL2 ka mea maʻamau e kōkua i nā cell granulosa e ulu pono.

He aha nā hōʻailona? Pehea ʻoe i ʻike ai?

Inā loaʻa kēia puʻupuʻu, ʻo ka hōʻailona nui ka piʻi ʻana o nā pae estrogen i loko o ke kino.

• No kahi kaikamahine liʻiliʻi, hiki i kēia ke kumu iā ia e hiki ai i ka wā ʻōpio.
• Hiki i nā wahine ʻelemakule ke loaʻa nā hōʻailona e like me:
• ʻO ke kahe koko ʻana o ka ʻōpū maʻamau ʻole (AUB) a i ʻole ke kahe koko ma hope o ka menopause.
• Piʻi a hoʻonui ʻia ka ʻāpana ʻōpū.
• Lilo nā pōʻaiapuni menstrual i mea ʻano ʻē a i ʻole e pau loa.
• ʻEha a me ka paʻa o ka umauma.
• I kekahi manawa, inā haki ka puʻupuʻu, hiki ke hōʻeha i ka ʻōpū.

He aha nā pilikia e hiki mai ana inā ʻaʻole mālama ʻia?

Inā ʻaʻole e mālama ʻia kēia `(Granulosa Cell Tumor)` i ka manawa kūpono, e piʻi aʻe paha ka pilikia o ka loaʻa ʻana o nā pilikia olakino ʻē aʻe. Eia kekahi laʻana:

• ʻO ka hyperplasia Endometrial kahi mānoanoa kūpono ʻole o ka paia o loko o ka ʻōpū.
• Ka maʻi ʻaʻai o ka ʻōpū.
• Ka maʻi ʻaʻai umauma.
• Ka paʻakikī i ka hānau keiki ʻana (Infertility).

Pehea ʻoe e ʻike ai i kēia?

Hoʻohana pinepine nā kauka i nā ʻano hana kiʻi like ʻole e ʻike ai i kahi Granulosa Cell Tumor. Pono paha ʻoe e loaʻa nā hoʻokolohua e like me kēia:

• He scan CT.
• He MRI.
• ʻO kahi hoʻokolokolo ultrasound i hana ʻia ma o ka vagina (Transvaginal ultrasound).

Eia kekahi, hiki i kāu kauka ke kauoha i nā hoʻāʻo koko. ʻO ke kikoʻī, e ʻimi lākou i kahi mea i kapa ʻia ʻo "Tumor Markers." ʻO "Inhibin" kahi ʻano "Tumor Marker" i hana ʻia e kēia "Granulosa Cell Tumor". Pono paha kekahi mau hoʻāʻo koko e hōʻoia ʻaʻohe mau maʻi ʻē aʻe.

Pehea e mālama ʻia ai?

ʻO ke ʻoki kino ka lāʻau mua no kēia "Granulosa Cell Tumor". Hoʻāʻo ke kauka ʻoki kino e wehe i ka nui o ka puʻupuʻu e like me ka hiki me ka mālama ʻana i nā ʻiʻo olakino.

Inā ʻaʻole ʻoe e hoʻolālā e loaʻa nā keiki hou aʻe, a inā ua hala ʻoe i ka makahiki hānau keiki, hiki i kāu kauka ke paipai i ka oophorectomy (ka wehe ʻana i nā ovaries) a i ʻole ka hysterectomy (ka wehe ʻana i ka uterus me nā ovaries). Pono paha ka oophorectomy e wehe loa i ka GCT.

Hoʻokaʻawale nā ​​kauka i kēia "Granulosa Cell Tumor" e like me kona wahi a inā ua pālahalaha, me ka hoʻohana ʻana i kahi kaʻina hana i kapa ʻia ʻo "Staging." Penei lākou e hoʻoholo ai inā ua pālahalaha ke kanesa a ʻaʻole paha.

• ʻO nā GCT o ka Papa 1 nā mea i pālahalaha ʻole ma mua o nā ovaries.
• ʻO ka pae 2 a 4 GCT nā mea i pālahalaha (metastasized) i nā ʻāpana ʻē aʻe o ke kino.

E noʻonoʻo i kēia: 9 o 10 o kēia mau GCT i loaʻa wale i loko o ka ovary. ʻO ka maʻamau, ʻōlelo ʻia ke ʻoki ʻana no kēia ʻano puʻupuʻu, a i kekahi manawa ua lawa paha kēlā wale nō.

Eia nō naʻe, ma muli o ka nui o ka puʻupuʻu a me kāu mau kumu pilikia no ka hoʻi hou ʻana, loaʻa paha nā lāʻau lapaʻau ʻē aʻe e kōkua i ka pale ʻana i ka puʻupuʻu mai ka hoʻi hou ʻana mai. Hiki i kāu kauka ke kuhikuhi i nā mea e like me:

• Kemoterapi.
• Ka lāʻau lapaʻau hormone.
• Hoʻōla radiation.

Aia kekahi ala e pale aku ai i kēia (Granulosa Cell Tumor) mai ka ulu ʻana?

ʻAʻohe hōʻoia e hiki iā ʻoe ke pale aku i ka ulu ʻana o kahi Granulosa Cell Tumor. Eia nō naʻe, hiki iā ʻoe ke kōkua ma ka lawe ʻana i kahi nohona olakino holoʻokoʻa a me ka hōʻemi ʻana i kou pilikia o ka loaʻa ʻana o nā maʻi maʻi :

• Ka mālama ʻana i kahi kaumaha olakino e kūpono i ke ʻano o kou kino, ke kāne, a me ka makahiki.
• Ke pale ʻana i ka puhipaka.
• Ka ʻai ʻana i ka meaʻai momona.
• Hoʻoikaika kino mau no ke olakino o ka naʻau a me ka iwi.
• Ka palena ʻana i ka waiʻona a me ka caffeine.
• Ke hoʻohana nei i nā ʻano hana olakino e like me ka "Mindfulness" a i ʻole "Meditation" e hoʻokele ai i ke kaumaha.
• E hiamoe maikaʻi ana i ʻehiku a ʻewalu hola i ka pō.

Pehea e hōʻemi ai i ka pilikia o nā pilikia?

Inā loaʻa iā ʻoe kekahi mau hōʻailona e hōʻike ana he GCT paha kāu, e ʻike koke i ke kauka. Inā loaʻa iā ʻoe ke kahe koko kūpono ʻole, ʻeha umauma, a i ʻole ke kahe koko ma hope o ka menopause, e ʻike pono i ke kauka. ʻOi aku ka maikaʻi o nā hopena o nā GCT ke mālama ʻia i ka wā mua.

Hiki ke ho'ōla loa ʻia ka Granulosa Cell Tumor?

ʻAe. Hiki ke ho'ōla ʻia nā GCT me ke ʻoki ʻana, ʻoiai inā e wehe mua ʻia.

Eia nō naʻe, inā ʻike ʻia ma hope o kona laha ʻana i nā ʻāpana ʻē aʻe o ke kino, haʻahaʻa ka manawa e hoʻōla ai. No laila, inā loaʻa iā ʻoe nā hōʻailona o ka GCT, e ʻike koke i ke kauka.

He aha kāu e manaʻo ai ma hope o ka lāʻau lapaʻau?

Ma hope o ka wehe ʻia ʻana o ka puʻupuʻu, pono ʻoe e ʻike pinepine i kāu kauka no ka nānā ʻana no kekahi mau makahiki. ʻO kēia no ka mea hiki i kēia mau puʻupuʻu ke hoʻi hou mai ma hope o nā makahiki he nui. E hana kāu kauka i kēia mau mea e nānā ai inā ua hoʻi mai ka puʻupuʻu:

• Nā hoʻokolokolo Pelvic.
• Nā hoʻāʻo koko e nānā i nā māka e hiki ke hoʻi mai ke kanesa.
• Nā hoʻāʻo kiʻi.

He aha ka manaʻo no ka ho'ōla hou ʻana?

ʻO ka nānā ʻana no kahi GCT e pili ana i ke kahua o ka maʻi i ka wā i ʻike ʻia ai. Inā ʻike ʻia kahi GCT ma mua o kona laha ʻana (metastasized) i nā ʻāpana ʻē aʻe o ke kino, ʻoi aku ka maikaʻi o ka nānā ʻana.

He aha hou aʻe kaʻu e nīnau aku ai i ke kauka?

Hiki iā ʻoe ke nīnau i kāu kauka i nā nīnau e like me kēia:

• He aha ke kumu kūpono loa o kēia mau hōʻailona?
• He aha nā hoʻokolohua e pono ai iaʻu e hana e ʻike ai inā he `(Granulosa Cell Tumor)` koʻu?
• He aha nā koho lapaʻau e loaʻa ana?
• He aha ka manawa kūpono e hoʻi mai ai kahi GCT ma hope o ka mālama ʻana?
• He aha ka wānana no ka ho'ōla ʻana ma hope o ka wehe ʻia ʻana o kahi `(Granulosa Cell Tumor)`?

ʻO ka mea hope loa, kekahi mau mea e hoʻomanaʻo ai (Leka Lawe-Home)

ʻAe, eia kekahi mau mea e hoʻomanaʻo ai i ka hōʻuluʻulu manaʻo e pili ana i ka `(Granulosa Cell Tumor)` a mākou i kamaʻilio ai:

• He ʻano puʻupuʻu laha ʻole kēia, lohi pinepine ka ulu ʻana e hana ana a puni nā ovaries.
• Hiki i kēia ke hana i ka hana nui ʻana o ka hormone "(Estrogen)," hiki ke hana i nā hōʻailona e like me ke kahe koko kūpono ʻole a me nā pōʻaiapuni menstrual kūpono ʻole.
• ʻO ke ʻano lapaʻau nui, ʻo ia ka wehe ʻana i ka puʻupuʻu me ke ʻoki kino.
• Inā aia kahi pilikia o ka hoʻi hou ʻana mai o ka puʻupuʻu, hiki i ke kauka ke ʻōlelo aku i ka chemotherapy, hormone therapy, a i ʻole radiation therapy.
• Inā ʻike mua ʻia kahi GCT, maikaʻi loa ka manawa e ho'ōla ai. No laila, inā loaʻa iā ʻoe nā hōʻailona, ​​e ʻike koke i ke kauka.

ʻO ka puʻupuʻu cell Granulosa, ka maʻi ʻaʻai ovarian, estrogen, olakino wahine, nā hōʻailona o ka maʻi ʻaʻai, ke ʻoki kino, nā pilikia hormonal