Ua lohe paha ʻoe i ka inoa ʻo Hydroxychloroquine ma ka nūhou i ka wā o ke ahulau COVID. Akā, he lāʻau kahiko loa ia i hoʻohana ʻia mai ka makahiki 1940. I nā lā mua, ua hoʻohana nā kauka iā ia e mālama i ka malaria. I kēia lā, hoʻohana pinepine ʻia ia no nā maʻi ʻē aʻe. I kēia lā, e kamaʻilio mākou e pili ana i ke ʻano o ka hoʻohana ʻia ʻana o kēia lāʻau, nā hopena ʻaoʻao e hiki ai ke hana, a me nā mea e makaʻala ai i ka wā e hoʻohana ai.
He kūpono maoli anei kēia lāʻau lapaʻau no Covid-19?
He nīnau kēia a ka poʻe he nui. I ka ʻōlelo maʻalahi, ʻaʻole . ʻAʻole ʻōlelo ka World Health Organization (WHO) i ka hydroxychloroquine no ka pale ʻana a i ʻole ka mālama ʻana i ka COVID-19. Ua hoʻoholo lākou i kēia ma hope o ka noiʻi nui ʻana.
E noʻonoʻo wale, ua ʻike ʻia he 6 mau noiʻi o nā tausani o ka poʻe me ka ʻole o COVID-19 ʻaʻohe hopena o ka lāʻau lapaʻau i ka pale ʻana iā lākou mai ka loaʻa ʻana o COVID, ka hoʻokomo ʻia ʻana i ka haukapila, a i ʻole ka make ʻana. A ua ʻike ʻia he 30 mau noiʻi o nā maʻi COVID-19 he 10,000 a ʻoi aku ʻaʻole i hōʻemi ka lāʻau lapaʻau i ka pono no nā mīkini hanu a i ʻole ka pilikia o ka make. ʻO ia ke kumu i ʻōlelo ʻole ʻia ai i kēia manawa no COVID-19.
No laila he aha ke ʻano o nā maʻi e hoʻohana ʻia ai kēia lāʻau lapaʻau?
ʻO ka Hydroxychloroquine ka mea i hoʻohana nui ʻia i kēia lā no nā maʻi autoimmune. I kēia manawa ke noʻonoʻo nei paha ʻoe i ke ʻano o ia mea.
I ka ʻōlelo maʻalahi, ʻo ia ka manawa e hoʻouka hewa ai ka ʻōnaehana pale ponoʻī o ko kākou kino, ʻo ia hoʻi ka ʻōnaehana pale maʻi, i ko kākou mau hunaola a me nā ʻiʻo olakino. ʻO kēia ke kumu o ka pehu ʻana a me ka hōʻino ʻana i nā hono, nā ʻiʻo, a i kekahi manawa nā ʻōpū o loko.
Hiki i kāu kauka ke kuhikuhi i kēia lāʻau lapaʻau nāu inā loaʻa iā ʻoe kekahi o kēia mau kūlana:
- ʻO ka ʻāʻī rheumatoid
- ʻO ka lupus erythematosus ʻōnaehana (SLE)
- ʻO ka ʻāʻī idiopathic ʻōpio
- ʻO ka maʻi Antiphospholipid
- ʻO ka maʻi Sjogren mua
ʻAʻole maopopo i nā loea pehea e hana ai kēia lāʻau lapaʻau, akā manaʻo lākou e hoʻololi ia i ke ʻano o ka hōʻailona ʻana o nā pūnaewele pale kino kekahi i kekahi. Hiki paha iā ia ke hoʻopau i kekahi o nā kaʻina hana e hoʻoulu ai i ka mumū.
He aha nā hopena ʻaoʻao e hiki ke loaʻa mai kēia lāʻau lapaʻau?
E like me nā lāʻau lapaʻau āpau, hiki i ka hydroxychloroquine ke hana i nā hopena ʻaoʻao. ʻOiai ʻaʻole loaʻa i nā kānaka a pau, he akahai kekahi mau hopena ʻaoʻao a nalo i ka hala ʻana o ka manawa.
| Nā hopena ʻaoʻao maʻamau | |
|---|---|
| Ka luaʻi | Ka luaʻi ʻana |
| Ka maʻi pākī | ʻEha ʻōpū |
| Manaʻo: No ka hōʻemi ʻana i kēia mau hopena ʻaoʻao, he mea kōkua paha ka lawe ʻana i kēia lāʻau lapaʻau me ka ʻai . | |
Eia kekahi, hiki ke loaʻa nā hōʻailona ʻē aʻe:
- ʻO ka ʻāʻī a i ʻole ka ʻulaʻula ma ka ʻili
- ʻEleʻele a ʻōniʻoniʻo paha o ka ʻili
- Nā loli o ka lauoho (e.g., loli o ke kala)
- Nāwaliwali o nā ʻiʻo
- Nā loli o ke ʻano
- Ke kani nei i nā pepeiao
Nā hopena ʻaoʻao koʻikoʻi e makaʻala
He mea koʻikoʻi iki kēia, no laila he mea nui loa ka makaʻala i kēia.
Nā hopena ma ka puʻuwai
Hiki i ka Hydroxychloroquine ke hoʻololi i ka puʻuwai. He ʻoiaʻiʻo loa kēia inā ʻoe e lawe pū me kekahi mau lāʻau lapaʻau ʻē aʻe, e like me azithromycin . Hiki i kēia ke hoʻololi i ka hana uila o ka puʻuwai. ʻO ke kikoʻī, hiki iā ia ke hoʻoulu i ka wikiwiki o ka puʻuwai (ventricular tachycardia) a i ʻole kahi loli weliweli i ka puʻuwai (lōʻihi o ka QT interval).
Ka pōʻino o ka maka
He mea nui loa kēia. ʻOiai he mea kakaikahi, hiki i ka hydroxychloroquine ke hōʻino i ka retina o ka maka.
Mai poina e hiki i kēia lāʻau lapaʻau ke hōʻino i kou mau maka. I kekahi mau hihia, hiki iā ʻoe ke nalowale loa kou ʻike.
Ua hoʻonui ʻia kēia pilikia i nā poʻe e like me:
- No nā poʻe ma luna o 60 mau makahiki
- No ka poʻe e lawe ana i nā lāʻau kiʻekiʻe o ka lāʻau no nā makahiki he 5 a ʻoi
- No ka poʻe me nā maʻi puʻupaʻa a i ʻole ke akepaʻa koʻikoʻi
- No ka poʻe i loaʻa mua i nā maʻi maka a retina paha
No laila, inā ʻoe e hoʻohana i kēia lāʻau lapaʻau no ka manawa lōʻihi, he mea nui e nānā pinepine ʻia kou mau maka e kahi ophthalmologist.E haʻi aku kāu kauka iā ʻoe e nānā i kou mau maka i hoʻokahi manawa i ka makahiki a i ʻole ma ka liʻiliʻi hoʻokahi manawa i kēlā me kēia 5 mau makahiki.
Nā hopena koʻikoʻi ʻē aʻe
- Nā maʻi o ka ʻōnaehana koko: ʻAʻole pinepine ka loaʻa ʻana o ka anemia, ʻoiai i ka poʻe me nā maʻi koko e like me ka hemahema o ka G6PD a i ʻole ka porphyria.
- Nā pilikia puʻupaʻa
- Ka hōʻino a i ʻole ka hana pono ʻole o ke akepaʻa
Nā Hana like ʻana o nā Lāʻau Lapaʻau
Hiki i ka Hydroxychloroquine ke launa pū me kekahi mau lāʻau lapaʻau. Hiki iā ia ke hoʻololi i ke ʻano o kā lākou hana a hoʻonui paha i ka pilikia o nā hopena ʻaoʻao. No laila he mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau, nā huaora, a i ʻole nā mea hoʻohui āu e lawe nei.
| ʻAno lāʻau lapaʻau | Nā mea e noʻonoʻo ai |
|---|---|
| Nā lāʻau lapaʻau ʻaʻole pono e lawe pū ʻia | ʻO Cisapride, Dronedarone, Pimozide, Thioridazine |
| Nā lāʻau lapaʻau e hiki ai ke hoʻoulu i nā hopena ʻaoʻao | ʻO Digoxin, insulin a i ʻole nā lāʻau lapaʻau maʻi diabetes ʻē aʻe, Mefloquine, nā lāʻau epilepsy, Methotrexate, Cyclosporine |
| Nā lāʻau lapaʻau e hiki ai ke hana i nā hopena ʻaoʻao ʻē aʻe | Praziquantel, Antacids, Kaolin, Cimetidine, Ampicillin |
Inā ʻoe e lawe ana i ka tamoxifen no ka maʻi ʻaʻai umauma, e kamaʻilio pū me kāu kauka e pili ana i kēlā. ʻAʻole paha kūpono ke lawe pū ʻana i kēia mau lāʻau ʻelua no nā mahina ʻeono a ʻoi.
ʻO wai ka mea hiki ke lawe i kēia lāʻau lapaʻau? ʻO wai ka mea hiki ʻole?
Palekana ka Hydroxychloroquine no ka hapa nui o nā pākeke a me nā keiki. Na kāu kauka e hoʻoholo i ka nui kūpono ma muli o ke kaumaha o kou kino.
ʻOiai ua hōʻike ʻia e ka noiʻi he palekana kēia lāʻau lapaʻau e lawe i ka wā hāpai a hānai waiū paha,E kamaʻilio pono me kāu kauka e pili ana i kekahi lāʻau lapaʻau āu e lawe ai.
Inā loaʻa iā ʻoe ka psoriasis , he maʻi ʻili, e makaʻala i kēlā no ka mea hiki i kēia lāʻau lapaʻau ke hoʻonui i kou mau hōʻailona.
ʻO wai ka mea pono ʻole e lawe i kēia lāʻau lapaʻau?
Inā he maʻi ʻoe i nā lāʻau lapaʻau ʻē aʻe i loaʻa nā pūhui 4-aminoquinoline, e like me chloroquine, ʻaʻole pono ʻoe e lawe i ka hydroxychloroquine.
Inā ʻike ʻoe i nā hōʻailona o kahi hopena maʻi, e hele koke i ka keʻena pilikia o ka haukapila kokoke loa (ETU). ʻO ia mau hōʻailona:
- Ka pehu ʻana o ka puʻu, ka waha, a i ʻole ka maka
- ʻŌhūhū ʻili a pehu paha
- ʻO ka maneʻo nui
Leka Lawe-Home
- He lāʻau lapaʻau ka Hydroxychloroquine i hoʻohana nui ʻia e mālama i nā maʻi autoimmune e like me ka rheumatoid arthritis a me ka lupus. ʻAʻole ia e ʻōlelo ʻia no COVID-19.
- Hiki i kēia lāʻau lapaʻau ke hoʻoulu i nā hopena ʻaoʻao koʻikoʻi i ka puʻuwai a ʻoi aku hoʻi i nā maka.
- Inā ʻoe e lawe ana i kēia lāʻau lapaʻau no ka manawa lōʻihi, he mea nui e hana i nā hoʻokolohua maka mau e like me ka ʻōlelo a kāu kauka.
- E haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei.
- Mai hoʻomaka a hoʻōki paha i ka lawe ʻana i kēia lāʻau me ka ʻole o ke aʻo ʻana a ke kauka.
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