E aʻo kākou e pili ana i ka Non-Hodgkin Lymphoma. Mai makaʻu, e kamaʻilio kākou!

Ua ʻike anei ʻoe i kahi puʻupuʻu liʻiliʻi ma kou ʻāʻī a i ʻole kou ʻāʻī? ʻO ka hapa nui o ka manawa, he mea maʻamau kēia, akā i kekahi manawa hiki iā lākou ke lilo i hōʻailona o kahi maʻi e like me ka lymphoma. I kēia lā ke kamaʻilio nei mākou e pili ana i kekahi ʻano maʻi kanesa, ʻo Non-Hodgkin Lymphoma. Mai makaʻu ke lohe ʻoe i kēia inoa. E hoʻomaopopo kākou i nā mea āpau e pili ana i kēia me ka maʻalahi a me ka maopopo.

I ka ʻōlelo maʻalahi, he aha ka lymphoma non-Hodgkin (NHL)?

ʻO ka Non-Hodgkin Lymphoma (NHL) kahi hui o nā maʻi ʻaʻai koko e ulu ana i loko o kā mākou ʻōnaehana lymphatic . I kēia manawa ke noʻonoʻo nei paha ʻoe i ke ʻano o ka ʻōnaehana lymphatic. He ʻāpana nui ia o ka ʻōnaehana pale o ko mākou kino. E like me ka pūʻali koa pale o ko mākou ʻāina, pale kēia ʻōnaehana iā mākou ma ke kaua ʻana i nā germs e hoʻoulu ai i nā maʻi.

Aia nā pūnaewele koa kūikawā e like me nā pūnaewele i loko o kēia ʻōnaehana lymphatic. Kāhea mākou iā lākou he mau lymphocytes . He ʻano kēia o nā pūnaewele koko keʻokeʻo. Ke loli nā genes o kēia mau pūnaewele lymphocyte, ʻo ia hoʻi, he mutation, hoʻomaka kēlā mau pūnaewele e māhele a hoʻonui me ke kāohi ʻole. ʻO ia ke kanesa e ulu ana ma kēia ʻano, kapa mākou iā ia he non-Hodgkin lymphoma.

Hoʻākoakoa pinepine kēia mau pūnaewele ʻano ʻē i loko o ko mākou mau lymph nodes a hana i nā puʻupuʻu . Hiki iā lākou ke laha i nā ʻōpū ʻē aʻe i loko o ka ʻōnaehana lymphatic, e like me ko mākou spleen.

Akā e hoʻomanaʻo i kēia: Me nā lāʻau lapaʻau holomua o kēia wā, ʻoi aku ka lōʻihi o ke ola o ka poʻe me ka lymphoma non-Hodgkin ma mua o ka wā ma mua. I kekahi manawa hiki i ka lāʻau lapaʻau ke ho'ōla loa i ka maʻi. I nā manawa ʻē aʻe, ʻo ka pahuhopu o ka lāʻau lapaʻau ka mālama ʻana i ka maʻi i ka wā hiki, me ka ʻole o nā hōʻailona.

Aia kekahi mau ʻano o kēia mau NHL?

ʻAe, aia ma mua o 70 mau ʻano nui o kēia maʻi. Akā ua māhele nui ʻia lākou e like me ke ʻano o ke kele lymphocyte i hoʻopilikia ʻia.

• ʻO ka lymphoma B-cell: Kū mai kēia mau mea mai kahi ʻano lymphocyte i kapa ʻia ʻo nā cell B. ʻO kēia mau cell B nā mea e hana i nā antibodies e hakakā i nā germs ke komo lākou i loko o ko mākou kino. Ma kahi o 85% o nā maʻi NHL no kēia māhele.
• lymphoma T-cell: Kū mai kēia mau mea mai kahi ʻano lymphocyte i kapa ʻia ʻo T cell. Ke kaua pololei nei kēia mau cell T i nā germs a kōkua pū i nā cell B.

Eia kekahi, hoʻokaʻawale pū nā kauka i kēia mau ʻano lymphoma e like me ka wikiwiki o ko lākou laha ʻana.

• Hoʻouka kaua: Hiki i kēia ʻano ke laha koke i loko o ke kino, no laila pono ia e mālama koʻikoʻi.
• Palaualelo: Lohi loa kēia ʻano . I kekahi manawa, ʻaʻole pono ka lāʻau lapaʻau i nā pae mua.

He aha nā hōʻailona o kēia maʻi?

ʻO ka hōʻailona maʻamau o kēia maʻi he pehu ʻeha ʻole a puʻupuʻu paha ma ka ʻāʻī, ka ʻāʻī lima, a i ʻole ka ʻūhā. Ua kapa ʻia kēia mau mea he mau lymph node pehu. Akā e hoʻomanaʻo, ʻaʻole ʻo ke kanesa wale nō ke kumu o nā lymph node pehu. Hiki ke hana kēia me ke anu a i ʻole ka maʻi flu.

Ma waho aʻe o kēlā, hiki ke ʻokoʻa nā hōʻailona ma muli o kahi i loaʻa ai nā hunaola kanesa. E nānā pono kākou i kēlā ma ka papa ma lalo.

He aha nā hōʻailona o ka maʻi B?

I ka wā e ʻike ai i ka lymphoma, ʻimi nā kauka i ʻekolu mau hōʻailona kikoʻī i kapa ʻia ʻo "nā hōʻailona B." Eia kēia:

1. Ke kuni me ke kumu ʻole

2. Ka hou nui ʻana i ka pō

3. Ka emi ʻana o ke kaumaha me ke kumu ʻole

Inā paha e loaʻa ana kēia mau hōʻailona a i ʻole e hiki ke kōkua i ka ʻike ʻana i ke ʻano o ka lymphoma āu e loaʻa ai a hoʻoholo i ka lāʻau maikaʻi loa.

He aha nā kumu pilikia no ka hoʻomohala ʻana i kēia maʻi?

ʻAʻole i ʻike ʻia ke kumu kikoʻī o ka lymphoma non-Hodgkin. Eia nō naʻe, ua ʻike ʻia kekahi mau mea e hoʻonui ai i ka likelika, a i ʻole ka pilikia, o ka hoʻomohala ʻana i kēia maʻi.

Pehea e ʻike ai i ka maʻi? (Diagnosis)

Ke hele ʻoe e ʻike i ke kauka, e hahai ʻo ia i kekahi mau ʻanuʻu e ʻike pono ai i ka maʻi.

• Hoʻokolohua kino: ʻO ka mea mua, e nīnau ke kauka iā ʻoe e pili ana i kāu mau hōʻailona a nānā i kou kino no nā hōʻailona e like me nā kīʻaha lymph pehu.
• Nā hoʻāʻo koko: ʻO nā hoʻāʻo e like me ka helu koko piha (CBC) hāʻawi i kahi manaʻo o kou olakino holoʻokoʻa.
• Nā hoʻāʻo kiʻi: Hiki i nā hoʻokolohua e like me CT scans, MRI scans, a me PET scans ke nānā i nā hunaola kanesa i loko o ke kino.
• Biopsy: ʻO kēia wale nō ke ala e hōʻoia ai i ka maʻi 100% o ka manawa. Pili kēia i ka lawe ʻana i kahi ʻāpana liʻiliʻi o ka ʻiʻo mai kahi lymph node pehu a i ʻole kahi a nānā iā ia ma lalo o kahi microscope. ʻO kēia wale nō ke ala e ʻike pono ai inā aia nā cell lymphoma a ʻaʻole paha.
• Immunophenotyping: He hoʻāʻo kūikawā kēia e nānā ana i nā pūnaewele i lawe ʻia mai kahi biopsy e kōkua i ka ʻike pololei i ke ʻano o ka NHL.

Nā pae o ka maʻi

Ma hope o nā hoʻokolohua, e hoʻoholo ke kauka i ke kahua o kou maʻi. He mea nui loa kēia no ka hoʻolālā ʻana i ka mālama ʻana.

He aha nā lāʻau lapaʻau?

ʻO ke ʻano o ka lāʻau lapaʻau āu e pono ai ma muli o nā kumu he nui, me ke ʻano o ka NHL āu, ke kahua o ka maʻi, a me kou olakino holoʻokoʻa.

• Nānā pono: Inā he ʻano palaualelo kou a ʻaʻohe ou hōʻailona, ​​​​hiki i kāu kauka ke hoʻoholo e nānā i kou holomua me ka ʻole o ka lāʻau lapaʻau. Maanei, e nānā mau ʻia ʻoe a hoʻomaka wale ʻia ka lāʻau lapaʻau inā loaʻa nā hōʻailona.
• Kemoterapi: ʻO kēia ke ʻano lapaʻau i hoʻohana nui ʻia. Pili ia i ka hāʻawi ʻana i nā lāʻau lapaʻau i ke kino e pepehi ai i nā hunaola kanesa.
• Lapaʻau i kuhikuhi ʻia: Kuhi kēia mau lāʻau a hoʻouka i kahi nāwaliwali kikoʻī i nā hunaola kanesa. ʻO ka lāʻau lapaʻau antibody monoclonal kekahi o ia ʻano lāʻau.
• Immunotherapy: Pili kēia i ka hoʻoulu ʻana i kāu ʻōnaehana pale ponoʻī e luku i nā hunaola maʻi kanesa. ʻO ka CAR T-cell therapy kekahi o ia ʻano lapaʻau holomua.
• Lapaʻau radiation: Pili kēia i ka hoʻohana ʻana i nā kukuna ikehu kiʻekiʻe (e like me nā kukuna X) e luku i nā hunaola kanesa.
• Hoʻoili ʻana i nā pūnaewele kumu: Hana pinepine ʻia kēia inā ʻaʻole i holo pono nā lāʻau ʻē aʻe. Pili kēia i ka hāʻawi ʻana i ka chemotherapy nui e pepehi i nā pūnaewele kanesa, a laila e hoʻokomo i nā pūnaewele kumu olakino i loko o ke kino.

Pehea e ola ai me ka maʻi?

I ke noho ʻana me NHL, aia kekahi mau mea hiki iā ʻoe ke hana e mālama iā ʻoe iho.

• E ʻai i ka meaʻai momona a maikaʻi. He ikehu ka meaʻai. Hiki i ka ʻai pono ke kōkua i ka mālama ʻana i ka ikehu o kou kino.
• E hoʻomaha nui e like me ka hiki. Hiki i ka lāʻau lapaʻau ke hoʻoluhi iā ʻoe. Kōkua ka hoʻomaha i kou kino e hoʻihoʻi i kona ikaika.
• E kāohi i ke kaumaha.ʻAʻole maʻalahi ka noho ʻana me ka maʻi kanesa. E kamaʻilio me kāu kauka, ʻohana, a i ʻole he hoaaloha hilinaʻi e pili ana i kou mau makaʻu a me nā kānalua.
• Hoʻoikaika kino. E noi i kāu kauka no kahi hana hoʻoikaika kino māmā e kūpono iā ʻoe.
• E aʻo e pili ana i ka mālama palliative. E pili ana kēia i ke kōkua ʻana e maʻalahi ke ola ma ka hōʻemi ʻana i ka ʻeha o ka mea maʻi, ka ʻoluʻolu ʻole, a me ke kaumaha, me ka nānā ʻole i ke kahua o ka maʻi.

Āhea wau e ʻike ai i ke kauka?

Inā ʻoe e mālama ʻia ana a ʻoi aʻe ka ʻino o kāu mau hōʻailona a i ʻole e ʻike ʻia nā hōʻailona hou , e hoʻomaopopo koke i kāu kauka. Ke pau ka mālama ʻana, e hōʻoia e hele i kāu mau manawa i hoʻonohonoho ʻia ma ke keʻena lapaʻau.

Āhea ʻoe e hele ai i ka Emergency Treatment Unit (ETU)?

Inā loaʻa iā ʻoe nā hōʻailona koʻikoʻi, no ka laʻana, ka paʻakikī nui o ka hanu ʻana a i ʻole ke kahe koko nui, e hele koke i ka ʻOihana Pilikia (ETU) o ka haukapila kokoke loa.