Nā mea āpau e pili ana i nā lāʻau lapaʻau no ka maʻi Parkinson: E kamaʻilio maʻalahi kākou

Aia kekahi o kou ʻohana, ʻo kou makuakāne paha, kou makuahine paha, a i ʻole kekahi āu i ʻike ai, e loaʻa ana i ka maʻi ʻo Parkinson? Ua kaumaha loa paha ʻoe i ka ʻike ʻana i ko lākou mau lima e haʻalulu ana, ko lākou paʻakikī i ka hele ʻana, ko lākou kino e ʻoʻoleʻa ana, a me ko lākou helehelena e nalowale ana i ka manaʻo. ʻAʻole maʻalahi ke ola me kēia maʻi. Akā ʻo ka mea maikaʻi loa, me ka ʻepekema lapaʻau holomua o kēia wā, me ka lāʻau lapaʻau kūpono, hiki iā ʻoe ke kāohi i kēia mau hōʻailona i kahi nui a ola i kahi ola maikaʻi. No laila i kēia lā, e kamaʻilio maʻalahi a me ke aloha e pili ana i nā lāʻau lapaʻau i hāʻawi ʻia no ka maʻi ʻo Parkinson.

ʻO ka mea mua, e nānā kākou, he aha ka maʻi ʻo Parkinson?

E hoʻomaopopo maʻalahi kākou i kēia. He maʻi ʻo Parkinson e pili ana i ko kākou ʻōnaehana nerve. ʻOi aku hoʻi, ko kākou lolo. He ʻano holomua ia e ʻoi aʻe ka ʻino i ka hala ʻana o ka manawa . Aia kahi wahi o ko kākou lolo i kapa ʻia ʻo 'substantia nigra' e kaohi ana i ka neʻe ʻana. Ua hōʻino ʻia nā hunaola nerve ma kēia wahi a make mālie.

Hoʻopuka kēia mau ʻaʻalolo i kahi ʻelele kemika koʻikoʻi loa, he `neurotransmitter`, no ko mākou kino. ʻO dopamine kona inoa. He mea nui kēia dopamine no ka neʻe ʻana o ko mākou kino e maʻalahi a kāohi ʻia. No laila, ke luku ʻia kēlā mau ʻaʻalolo, emi ka pae o ka dopamine i loko o ka lolo. ʻO ia ke kumu e ʻike ʻia ai nā hōʻailona e like me ka haʻalulu, ka paʻakikī i ka hele wāwae, a me ka ʻoʻoleʻa i ka maʻi o Parkinson.

Nā lāʻau lapaʻau nui no ka maʻi o Parkinson

I ka mālama ʻana i ka maʻi o Parkinson, hoʻohana pinepine nā kauka i ka hui pū ʻana o kekahi mau lāʻau lapaʻau, ma mua o hoʻokahi lāʻau lapaʻau. ʻOkoʻa kēia ma muli o nā hōʻailona o ke kanaka, ka makahiki, a me ke kahua o ka maʻi. E nānā kākou i nā ʻano lāʻau lapaʻau nui.

1. ʻO Levodopa a me Carbidopa

ʻO kēia ka lāʻau lapaʻau nui a maikaʻi loa no ka maʻi o Parkinson. Ua kapa ʻia hoʻi ʻo ia ke kūlana gula.

• ʻO Levodopa: Ke komo kēia lāʻau lapaʻau i loko o ko mākou kino, komo ia i loko o ka lolo a lilo i dopamine. ʻO ia hoʻi, hoʻihoʻi kēia lāʻau lapaʻau i ka nui o ka dopamine i hoʻopau ʻia i loko o ka lolo.
• Carbidopa: Akā aia kahi pilikia. Inā lawe mākou i ka levodopa wale nō, ua luku ʻia ka hapa nui e nā enzymes i loko o ko mākou kino ma mua o ka hiki ʻana i ka lolo. No ka hoʻōki ʻana i kēia, hāʻawi pū ʻia kahi lāʻau i kapa ʻia ʻo carbidopa me ka levodopa. ʻAe ʻo Carbidopa i ka nui o ka levodopa e hiki i ka lolo me ka palekana. Eia kekahi, kōkua ʻo carbidopa i ka hōʻemi ʻana i nā hopena ʻaoʻao o ka lawe ʻana i ka levodopa wale nō, e like me ka nausea a me ka luaʻi.

ʻO kēia hui pū ʻana o nā lāʻau lapaʻau e hana pinepine maikaʻi loa no nā hōʻailona o ka bradykinesia, ka ʻoʻoleʻa, a me ka haʻalulu.

2. Nā Agonists Dopamine

Ua like kēia ʻano lāʻau lapaʻau me kahi mea hana keaka. ʻO ia hoʻi, ʻaʻole ia he dopamine maoli. Akā, hele ia i ka lolo a hana e like me ka dopamine. Hoʻoulu ia i nā mea loaʻa dopamine i loko o ka lolo, e hāʻawi ana i ka lolo i ka manaʻo aia ka dopamine ma laila.

Hoʻomaopopo pinepine ʻia kēia mau lāʻau lapaʻau i nā pae mua o ka maʻi, ʻoi aku hoʻi i nā poʻe maʻi ʻōpio. Hiki iā lākou ke kōkua i kekahi manawa e hoʻolōʻihi i ka pono o ka levodopa.

• ʻO Pramipexole (Mirapex®)
• ʻO Ropinirole (Requip®)
• ʻO Rotigotine (Neupro®)

3. Nā mea pale ʻenzyme

Mai makaʻu ʻoe ke lohe ʻoe i kēia inoa. He mea maʻalahi loa ia. Ua ʻōlelo mākou ma mua he mau enzymes i loko o ko mākou kino e wāwahi ana i ka dopamine. ʻO ka hana a kēia mau lāʻau lapaʻau, ʻo ia ke hoʻōki i ka hana o kēlā mau enzymes. A laila, ʻaʻole e luku ʻia ka dopamine i loko o ka lolo no ka manawa lōʻihi.

ʻElua ʻano nui o kēia mau mea:

• Nā mea pale MAO-B: Ke ālai nei kēia i ka hana o `MAO-B`, kahi enzyme nui e wāwahi i ka dopamine i loko o ka lolo. Nā laʻana: `Selegiline`, `Rasagiline`.
• Nā mea pale COMT: Ke kāohi nei kēia i ka enzyme `COMT` e wāwahi ana i ka dopamine, i hana ʻia mai ka levodopa. Ma muli o kēia, ʻoi aku ka lōʻihi o ka hopena o ka levodopa. Nā laʻana: `Entacapone`, `Opicapone`.

4. ʻAmantadine

Hiki i kekahi mau maʻi e lawe ana i nā lāʻau lapaʻau e like me levodopa no ka manawa lōʻihi ke hoʻomohala i nā neʻe ʻana me ka makemake ʻole a me ka wikiwiki (dyskinesia). Hoʻohana nui ʻia ʻo Amantadine e mālama i kēia mau kūlana. ʻO ka mea kupanaha, ua hoʻomohala mua ʻia ʻo ia ma ke ʻano he lāʻau antiviral. Akā ua ʻike ʻia ma hope e kōkua pū i nā hōʻailona o Parkinson.

5. Nā lāʻau lapaʻau Anticholinergic

Kōkua nui kēia lāʻau lapaʻau i ka haʻalulu a me ka paʻakikī.Kaohi. Ke emi ka dopamine i loko o ko kākou lolo, piʻi ka hopena o kekahi 'neurotransmitter' ʻē aʻe i kapa ʻia ʻo acetylcholine. Ke ālai nei kēia mau lāʻau i ka hopena o kēlā acetylcholine. Nā laʻana: 'Benztropine', 'Trihexyphenidyl'.

Nā lāʻau lapaʻau no nā hōʻailona ʻē aʻe i pili ʻole i ka neʻe ʻana

ʻAʻole wale ka maʻi o Parkinson e hoʻopilikia i ka neʻe ʻana. Hiki iā ia ke hana i nā pilikia ʻē aʻe, e like me ka paʻa ʻana o ka ʻōpū, nā pilikia hiamoe, ke kaumaha, a me ka hana pono ʻole o ka moekolohe. E kuhikuhi kāu kauka i ka lāʻau lapaʻau no kēlā me kēia o kēia.

E aʻo pū kākou e pili ana i nā hopena ʻaoʻao o kēia mau lāʻau lapaʻau.

E like me nā lāʻau lapaʻau a pau, hiki i nā lāʻau lapaʻau o Parkinson ke loaʻa nā hopena ʻaoʻao. He mea nui e ʻike mua i kēia mau mea. Eia naʻe, ʻaʻole i loaʻa i nā kānaka a pau kēia mau hopena ʻaoʻao. Eia kekahi, nalowale kekahi o kēia mau mea i ka hoʻomau ʻia ʻana o ka hoʻohana ʻana i ka lāʻau lapaʻau.

ʻAʻole lawa ka lāʻau lapaʻau? He aha hou aʻe e hiki ke hana ʻia?

ʻO ka lāʻau lapaʻau kekahi hapa wale nō o ke kaua. Inā ʻoe e hana i kekahi mau mea ʻē aʻe me ka lāʻau lapaʻau, hiki iā ʻoe ke kaohi maikaʻi i kāu mau hōʻailona a noho hauʻoli.

Hoʻōla kino

He mea kēia e hana ai. Aia nā papahana hoʻōla kino no nā maʻi o Parkinson. E kōkua kēia iā ʻoe,

• Hiki iā ʻoe ke hoʻomaikaʻi i ke kaulike a me ka hele ʻana o kou kino.
• Hiki iā ia ke hoʻonui i ke kūpaʻa o ke kino.
• He kōkua nui ia i ka mālama ʻana i kahi ola hana.

Hoʻoikaika kino

ʻO ka hoʻoikaika kino ke ala maikaʻi loa e mālama ai i ka maʻi Parkinson. ʻO ka hoʻoikaika kino wale nō ka mea i hōʻoia ʻia e ka ʻepekema e hoʻolohi i ka holomua o ka maʻi. ʻOi aku ka maikaʻi o ka hana ʻana ma ka liʻiliʻi he 150 mau minuke o ka hoʻoikaika kino cardiovascular i kēlā me kēia pule. He mea kōkua nui nā mea e like me ke kaʻa paikikala, ka mokomoko, a me ka hoʻoikaika kino me ke mele.

Ka mālama ʻana i ke olakino noʻonoʻo

I ka wā e noho ana me kahi maʻi lōʻihi e like me Parkinson, he mea maʻamau ka manaʻo kaumaha, hopohopo, a me ka hopohopo. No laila, inā ʻoe e manaʻo nei i kēia ʻano, he mea nui e hilahila ʻole iā ia a e ʻimi i ke kōkua mai kahi loea olakino noʻonoʻo, e like me ke kauka noʻonoʻo .

Āhea ʻoe e ʻike hou ai i kāu kauka?

I ka wā e hoʻohana ai i ka lāʻau lapaʻau o Parkinson, he mea nui e ʻike pinepine i kāu kauka e nānā inā e hana ana ka lāʻau lapaʻau a inā paha ua ulu mai nā hōʻailona hou. E hōʻoia e ʻike i kāu kauka ma ia mau hihia.

• Inā loaʻa iā ʻoe nā hopena ʻaoʻao ʻaʻole hiki iā ʻoe ke ʻae .
• Inā ʻaʻole e hoʻomaikaʻi a ʻoi aku paha ka ʻino o kāu mau hōʻailona .
• Inā makemake ʻoe e hoʻōki i kāu lāʻau lapaʻau . (Mai hana hoʻokahi i kēia hoʻoholo!)